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Items: 1 to 50 of 68

1.

Changing climate both increases and decreases European river floods.

Blöschl G, Hall J, Viglione A, Perdigão RAP, Parajka J, Merz B, Lun D, Arheimer B, Aronica GT, Bilibashi A, Boháč M, Bonacci O, Borga M, Čanjevac I, Castellarin A, Chirico GB, Claps P, Frolova N, Ganora D, Gorbachova L, Gül A, Hannaford J, Harrigan S, Kireeva M, Kiss A, Kjeldsen TR, Kohnová S, Koskela JJ, Ledvinka O, Macdonald N, Mavrova-Guirguinova M, Mediero L, Merz R, Molnar P, Montanari A, Murphy C, Osuch M, Ovcharuk V, Radevski I, Salinas JL, Sauquet E, Šraj M, Szolgay J, Volpi E, Wilson D, Zaimi K, Živković N.

Nature. 2019 Sep;573(7772):108-111. doi: 10.1038/s41586-019-1495-6. Epub 2019 Aug 28.

PMID:
31462777
2.

Geographic Variation and Bias in the Polygenic Scores of Complex Diseases and Traits in Finland.

Kerminen S, Martin AR, Koskela J, Ruotsalainen SE, Havulinna AS, Surakka I, Palotie A, Perola M, Salomaa V, Daly MJ, Ripatti S, Pirinen M.

Am J Hum Genet. 2019 Jun 6;104(6):1169-1181. doi: 10.1016/j.ajhg.2019.05.001. Epub 2019 May 30.

PMID:
31155286
3.

Correction: Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS, Beaugerie L, Seksik P, Cosnes J, Schreiber S, Bokemeyer B, Bethge J; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; T2D-GENES Consortium, Heap G, Ahmad T, Plagnol V, Segal AW, Targan S, Turner D, Saavalainen P, Farkkila M, Kontula K, Palotie A, Brant SR, Duerr RH, Silverberg MS, Rioux JD, Weersma RK, Franke A, Jostins L, Anderson CA, Barrett JC, MacArthur DG, Jalas C, Sokol H, Xavier RJ, Pulver A, Cho JH, McGovern DPB, Daly MJ.

PLoS Genet. 2019 May 30;15(5):e1008190. doi: 10.1371/journal.pgen.1008190. eCollection 2019 May.

4.

Robust model selection between population growth and multiple merger coalescents.

Koskela J, Wilke Berenguer M.

Math Biosci. 2019 May;311:1-12. doi: 10.1016/j.mbs.2019.03.004. Epub 2019 Mar 6.

PMID:
30851276
5.

Atherogenic index of plasma is related to arterial stiffness but not to blood pressure in normotensive and never-treated hypertensive subjects.

Choudhary MK, Eräranta A, Koskela J, Tikkakoski AJ, Nevalainen PI, Kähönen M, Mustonen J, Pörsti I.

Blood Press. 2019 Jun;28(3):157-167. doi: 10.1080/08037051.2019.1583060. Epub 2019 Mar 1.

PMID:
30821503
6.

Association of Genetic Variants in NUDT15 With Thiopurine-Induced Myelosuppression in Patients With Inflammatory Bowel Disease.

Walker GJ, Harrison JW, Heap GA, Voskuil MD, Andersen V, Anderson CA, Ananthakrishnan AN, Barrett JC, Beaugerie L, Bewshea CM, Cole AT, Cummings FR, Daly MJ, Ellul P, Fedorak RN, Festen EAM, Florin TH, Gaya DR, Halfvarson J, Hart AL, Heerasing NM, Hendy P, Irving PM, Jones SE, Koskela J, Lindsay JO, Mansfield JC, McGovern D, Parkes M, Pollok RCG, Ramakrishnan S, Rampton DS, Rivas MA, Russell RK, Schultz M, Sebastian S, Seksik P, Singh A, So K, Sokol H, Subramaniam K, Todd A, Annese V, Weersma RK, Xavier R, Ward R, Weedon MN, Goodhand JR, Kennedy NA, Ahmad T; IBD Pharmacogenetics Study Group.

JAMA. 2019 Feb 26;321(8):773-785. doi: 10.1001/jama.2019.0709. Erratum in: JAMA. 2019 Apr 23;321(16):1636.

7.

Severe mood disorders and schizophrenia in the adult offspring of antenatally depressed mothers in the Northern Finland 1966 Birth Cohort: Relationship to parental severe mental disorder.

Taka-Eilola Nèe Riekki T, Veijola J, Murray GK, Koskela J, Mäki P.

J Affect Disord. 2019 Apr 15;249:63-72. doi: 10.1016/j.jad.2019.02.011. Epub 2019 Feb 6.

PMID:
30759404
8.

Cat ownership in childhood and development of schizophrenia.

Palomäki J, Koskela J, Suvisaari J, Yolken R, Torrey F, Veijola J.

Schizophr Res. 2019 Apr;206:444-445. doi: 10.1016/j.schres.2018.12.020. Epub 2018 Dec 29. No abstract available.

PMID:
30598399
9.

Changes in short term river flow regulation and hydropeaking in Nordic rivers.

Ashraf FB, Haghighi AT, Riml J, Alfredsen K, Koskela JJ, Kløve B, Marttila H.

Sci Rep. 2018 Nov 22;8(1):17232. doi: 10.1038/s41598-018-35406-3.

10.

LDL cholesterol is associated with systemic vascular resistance and wave reflection in subjects naive to cardiovascular drugs.

Choudhary MK, Eräranta A, Tikkakoski AJ, Koskela J, Hautaniemi EJ, Kähönen M, Mustonen J, Pörsti I.

Blood Press. 2019 Feb;28(1):4-14. doi: 10.1080/08037051.2018.1521263. Epub 2018 Oct 29.

PMID:
30369274
11.

Hierarchical Cascading Algorithm for 2-D FEM Simulation of Finite SAW Devices.

Koskela J, Plessky V, Willemsen B, Turner P, Hammond B, Fenzi N.

IEEE Trans Ultrason Ferroelectr Freq Control. 2018 Oct;65(10):1933-1942. doi: 10.1109/TUFFC.2018.2852603. Epub 2018 Jul 2.

PMID:
29994395
12.

Multi-locus data distinguishes between population growth and multiple merger coalescents.

Koskela J.

Stat Appl Genet Mol Biol. 2018 Jun 13;17(3). pii: /j/sagmb.2018.17.issue-3/sagmb-2017-0011/sagmb-2017-0011.xml. doi: 10.1515/sagmb-2017-0011.

PMID:
29897888
13.

Insights into the genetic epidemiology of Crohn's and rare diseases in the Ashkenazi Jewish population.

Rivas MA, Avila BE, Koskela J, Huang H, Stevens C, Pirinen M, Haritunians T, Neale BM, Kurki M, Ganna A, Graham D, Glaser B, Peter I, Atzmon G, Barzilai N, Levine AP, Schiff E, Pontikos N, Weisburd B, Lek M, Karczewski KJ, Bloom J, Minikel EV, Petersen BS, Beaugerie L, Seksik P, Cosnes J, Schreiber S, Bokemeyer B, Bethge J; International IBD Genetics Consortium; NIDDK IBD Genetics Consortium; T2D-GENES Consortium, Heap G, Ahmad T, Plagnol V, Segal AW, Targan S, Turner D, Saavalainen P, Farkkila M, Kontula K, Palotie A, Brant SR, Duerr RH, Silverberg MS, Rioux JD, Weersma RK, Franke A, Jostins L, Anderson CA, Barrett JC, MacArthur DG, Jalas C, Sokol H, Xavier RJ, Pulver A, Cho JH, McGovern DPB, Daly MJ.

PLoS Genet. 2018 May 24;14(5):e1007329. doi: 10.1371/journal.pgen.1007329. eCollection 2018 May. Erratum in: PLoS Genet. 2019 May 30;15(5):e1008190.

14.

The effect of mechanical dry coating with magnesium stearate on flowability and compactibility of plastically deforming microcrystalline cellulose powders.

Koskela J, Morton DAV, Stewart PJ, Juppo AM, Lakio S.

Int J Pharm. 2018 Feb 15;537(1-2):64-72. doi: 10.1016/j.ijpharm.2017.11.068. Epub 2017 Dec 1.

PMID:
29198809
15.

Voluntary liquorice ingestion increases blood pressure via increased volume load, elevated peripheral arterial resistance, and decreased aortic compliance.

Hautaniemi EJ, Tahvanainen AM, Koskela JK, Tikkakoski AJ, Kähönen M, Uitto M, Sipilä K, Niemelä O, Mustonen J, Pörsti IH.

Sci Rep. 2017 Sep 8;7(1):10947. doi: 10.1038/s41598-017-11468-7.

16.

Changing climate shifts timing of European floods.

Blöschl G, Hall J, Parajka J, Perdigão RAP, Merz B, Arheimer B, Aronica GT, Bilibashi A, Bonacci O, Borga M, Čanjevac I, Castellarin A, Chirico GB, Claps P, Fiala K, Frolova N, Gorbachova L, Gül A, Hannaford J, Harrigan S, Kireeva M, Kiss A, Kjeldsen TR, Kohnová S, Koskela JJ, Ledvinka O, Macdonald N, Mavrova-Guirguinova M, Mediero L, Merz R, Molnar P, Montanari A, Murphy C, Osuch M, Ovcharuk V, Radevski I, Rogger M, Salinas JL, Sauquet E, Šraj M, Szolgay J, Viglione A, Volpi E, Wilson D, Zaimi K, Živković N.

Science. 2017 Aug 11;357(6351):588-590. doi: 10.1126/science.aan2506.

PMID:
28798129
17.

Haemodynamic Influences of Bisoprolol in Hypertensive Middle-Aged Men: A Double-Blind, Randomized, Placebo-Controlled Cross-Over Study.

Suojanen L, Haring A, Tikkakoski A, Koskela JK, Tahvanainen AM, Huhtala H, Kähönen M, Sipilä K, Eräranta A, Mustonen JT, Kivistö K, Pörsti IH.

Basic Clin Pharmacol Toxicol. 2017 Aug;121(2):130-137. doi: 10.1111/bcpt.12771. Epub 2017 May 3.

18.

Thermal sensitivity of growth indicates heritable variation in 1-year-old rainbow trout (Oncorhynchus mykiss).

Janhunen M, Koskela J, Ninh NH, Vehviläinen H, Koskinen H, Nousiainen A, Thỏa NP.

Genet Sel Evol. 2016 Nov 29;48(1):94.

19.

Characterization of sputum biomarkers for asthma-COPD overlap syndrome.

Gao J, Iwamoto H, Koskela J, Alenius H, Hattori N, Kohno N, Laitinen T, Mazur W, Pulkkinen V.

Int J Chron Obstruct Pulmon Dis. 2016 Sep 30;11:2457-2465. eCollection 2016. Erratum in: Int J Chron Obstruct Pulmon Dis. 2017 Apr 18;12 :1191.

20.

Capturing neutral and adaptive genetic diversity for conservation in a highly structured tree species.

Rodríguez-Quilón I, Santos-Del-Blanco L, Serra-Varela MJ, Koskela J, González-Martínez SC, Alía R.

Ecol Appl. 2016 Oct;26(7):2254-2266. doi: 10.1002/eap.1361. Epub 2016 Sep 21.

PMID:
27755736
21.

The effect of prenatal smoking exposure on daily smoking among teenage offspring.

Niemelä S, Räisänen A, Koskela J, Taanila A, Miettunen J, Ramsay H, Veijola J.

Addiction. 2017 Jan;112(1):134-143. doi: 10.1111/add.13533. Epub 2016 Sep 21.

PMID:
27444807
22.

Increased Cardiac Workload in the Upright Posture in Men: Noninvasive Hemodynamics in Men Versus Women.

Kangas P, Tahvanainen A, Tikkakoski A, Koskela J, Uitto M, Viik J, Kähönen M, Kööbi T, Mustonen J, Pörsti I.

J Am Heart Assoc. 2016 Jun 21;5(6). pii: e002883. doi: 10.1161/JAHA.115.002883.

23.

Central wave reflection is associated with peripheral arterial resistance in addition to arterial stiffness in subjects without antihypertensive medication.

Wilenius M, Tikkakoski AJ, Tahvanainen AM, Haring A, Koskela J, Huhtala H, Kähönen M, Kööbi T, Mustonen JT, Pörsti IH.

BMC Cardiovasc Disord. 2016 Jun 7;16:131. doi: 10.1186/s12872-016-0303-6.

24.

The type of the functional cardiovascular response to upright posture is associated with arterial stiffness: a cross-sectional study in 470 volunteers.

Tahvanainen AM, Tikkakoski AJ, Koskela JK, Nordhausen K, Viitala JM, Leskinen MH, Kähönen MA, Kööbi T, Uitto MT, Viik J, Mustonen JT, Pörsti IH.

BMC Cardiovasc Disord. 2016 May 23;16:101. doi: 10.1186/s12872-016-0281-8.

25.

High intensity focused ultrasound induced in vivo large volume hyperthermia under 3D MRI temperature control.

Tillander M, Hokland S, Koskela J, Dam H, Andersen NP, Pedersen M, Tanderup K, Ylihautala M, Köhler M.

Med Phys. 2016 Mar;43(3):1539-49. doi: 10.1118/1.4942378.

PMID:
26936737
26.

Individual FEV1 Trajectories Can Be Identified from a COPD Cohort.

Koskela J, Katajisto M, Kallio A, Kilpeläinen M, Lindqvist A, Laitinen T.

COPD. 2016 Aug;13(4):425-30. doi: 10.3109/15412555.2015.1043423. Epub 2016 Jan 25.

PMID:
26807738
27.

Physical activity in COPD patients decreases short-acting bronchodilator use and the number of exacerbations.

Katajisto M, Koskela J, Lindqvist A, Kilpeläinen M, Laitinen T.

Respir Med. 2015 Oct;109(10):1320-5. doi: 10.1016/j.rmed.2015.08.001. Epub 2015 Aug 6.

28.

Intercostal high intensity focused ultrasound for liver ablation: The influence of beam shaping on sonication efficacy and near-field risks.

de Greef M, Schubert G, Wijlemans JW, Koskela J, Bartels LW, Moonen CT, Ries M.

Med Phys. 2015 Aug;42(8):4685-97. doi: 10.1118/1.4925056.

PMID:
26233196
29.

Alcohol Abuse Increases Rebleeding Risk and Mortality in Patients with Non-variceal Upper Gastrointestinal Bleeding.

Kärkkäinen JM, Miilunpohja S, Rantanen T, Koskela JM, Jyrkkä J, Hartikainen J, Paajanen H.

Dig Dis Sci. 2015 Dec;60(12):3707-15. doi: 10.1007/s10620-015-3806-6. Epub 2015 Jul 16.

PMID:
26177705
30.

Lower glomerular filtration rate is associated with higher systemic vascular resistance in patients without prevalent kidney disease.

Vääräniemi K, Koskela J, Tahvanainen A, Tikkakoski A, Wilenius M, Kähönen M, Kööbi T, Niemelä O, Mustonen J, Pörsti I.

J Clin Hypertens (Greenwich). 2014 Oct;16(10):722-8. doi: 10.1111/jch.12405. Epub 2014 Sep 17.

31.

Stochastic ray tracing for simulation of high intensity focal ultrasound therapy.

Koskela J, Vahala E, de Greef M, Lafitte LP, Ries M.

J Acoust Soc Am. 2014 Sep;136(3):1430. doi: 10.1121/1.4892768.

PMID:
25190416
32.

Daily liquorice consumption for two weeks increases augmentation index and central systolic and diastolic blood pressure.

Leskinen MH, Hautaniemi EJ, Tahvanainen AM, Koskela JK, Päällysaho M, Tikkakoski AJ, Kähönen M, Kööbi T, Niemelä O, Mustonen J, Pörsti IH.

PLoS One. 2014 Aug 25;9(8):e105607. doi: 10.1371/journal.pone.0105607. eCollection 2014.

33.

Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD.

Koskela J, Kilpeläinen M, Kupiainen H, Mazur W, Sintonen H, Boezen M, Lindqvist A, Postma D, Laitinen T.

BMC Pulm Med. 2014 Jun 19;14:102. doi: 10.1186/1471-2466-14-102.

34.

Light-fuelled transport of large dendrimers and proteins.

Koskela JE, Liljeström V, Lim J, Simanek EE, Ras RH, Priimagi A, Kostiainen MA.

J Am Chem Soc. 2014 May 14;136(19):6850-3. doi: 10.1021/ja502623m. Epub 2014 May 6.

PMID:
24785836
35.

Longitudinal HRQoL shows divergent trends and identifies constant decliners in asthma and COPD.

Koskela J, Kupiainen H, Kilpeläinen M, Lindqvist A, Sintonen H, Pitkäniemi J, Laitinen T.

Respir Med. 2014 Mar;108(3):463-71. doi: 10.1016/j.rmed.2013.12.001. Epub 2013 Dec 20.

36.

Vulnerability of dynamic genetic conservation units of forest trees in Europe to climate change.

Schueler S, Falk W, Koskela J, Lefèvre F, Bozzano M, Hubert J, Kraigher H, Longauer R, Olrik DC.

Glob Chang Biol. 2014 May;20(5):1498-511. doi: 10.1111/gcb.12476. Epub 2014 Apr 5.

PMID:
24273066
37.

Association of resting heart rate with cardiovascular function: a cross-sectional study in 522 Finnish subjects.

Koskela JK, Tahvanainen A, Haring A, Tikkakoski AJ, Ilveskoski E, Viitala J, Leskinen MH, Lehtimäki T, Kähönen MA, Kööbi T, Niemelä O, Mustonen JT, Pörsti IH.

BMC Cardiovasc Disord. 2013 Nov 15;13:102. doi: 10.1186/1471-2261-13-102.

38.

Response initiation in young adults at risk for psychosis in the Northern Finland 1986 Birth Cohort.

Mukkala S, Ilonen T, Koskela J, Nordström T, Loukkola J, Miettunen J, Barnett JH, Murray GK, Jones PB, Heinimaa M, Jääskeläinen E, Mäki P, Moilanen I, Veijola J.

Cogn Neuropsychiatry. 2014;19(3):226-40. doi: 10.1080/13546805.2013.840569. Epub 2013 Oct 16.

PMID:
24131203
39.

Differences in plasma and sputum biomarkers between COPD and COPD-asthma overlap.

Iwamoto H, Gao J, Koskela J, Kinnula V, Kobayashi H, Laitinen T, Mazur W.

Eur Respir J. 2014 Feb;43(2):421-9. doi: 10.1183/09031936.00024313. Epub 2013 Jun 21.

40.

Hemodynamic alterations in hypertensive patients at rest and during passive head-up tilt.

Tikkakoski AJ, Tahvanainen AM, Leskinen MH, Koskela JK, Haring A, Viitala J, Kähönen MA, Kööbi T, Niemelä O, Mustonen JT, Pörsti IH.

J Hypertens. 2013 May;31(5):906-15. doi: 10.1097/HJH.0b013e32835ed605.

PMID:
23412427
41.

Dynamic conservation of forest genetic resources in 33 European countries.

Lefèvre F, Koskela J, Hubert J, Kraigher H, Longauer R, Olrik DC, Schüler S, Bozzano M, Alizoti P, Bakys R, Baldwin C, Ballian D, Black-Samuelsson S, Bednarova D, Bordács S, Collin E, de Cuyper B, de Vries SM, Eysteinsson T, Frýdl J, Haverkamp M, Ivankovic M, Konrad H, Koziol C, Maaten T, Notivol Paino E, Oztürk H, Pandeva ID, Parnuta G, Pilipovič A, Postolache D, Ryan C, Steffenrem A, Varela MC, Vessella F, Volosyanchuk RT, Westergren M, Wolter F, Yrjänä L, Zariŋa I.

Conserv Biol. 2013 Apr;27(2):373-84. doi: 10.1111/j.1523-1739.2012.01961.x. Epub 2012 Dec 12.

PMID:
23240629
42.

Dietary phosphate binding and loading alter kidney angiotensin-converting enzyme mRNA and protein content in 5/6 nephrectomized rats.

Eräranta A, Riutta A, Fan M, Koskela J, Tikkanen I, Lakkisto P, Niemelä O, Parkkinen J, Mustonen J, Pörsti I.

Am J Nephrol. 2012;35(5):401-8. doi: 10.1159/000337942. Epub 2012 Apr 19.

PMID:
22517117
43.

High intensity focused ultrasound with large aperture transducers: a MRI based focal point correction for tissue heterogeneity.

Mougenot C, Tillander M, Koskela J, Köhler MO, Moonen C, Ries M.

Med Phys. 2012 Apr;39(4):1936-45. doi: 10.1118/1.3693051.

PMID:
22482615
44.

Allelic variant of NOS1AP effects on cardiac alternans of repolarization during exercise testing.

Koskela J, Kähönen M, Nieminen T, Lehtinen R, Viik J, Nikus K, Niemelä K, Kööbi T, Tobin MD, Samani NJ, Turjanmaa V, Pörsti I, Lehtimäki T.

Scand J Clin Lab Invest. 2012 Apr;72(2):100-7. doi: 10.3109/00365513.2011.638725. Epub 2011 Dec 1.

PMID:
22133205
45.

Reduced systemic vascular resistance in healthy volunteers with presyncopal symptoms during a nitrate-stimulated tilt-table test.

Tahvanainen A, Koskela J, Leskinen M, Ilveskoski E, Nordhausen K, Kähönen M, Kööbi T, Mustonen J, Pörsti I.

Br J Clin Pharmacol. 2011 Jan;71(1):41-51. doi: 10.1111/j.1365-2125.2010.03794.x.

46.

Quality and production trait genetics of farmed European whitefish, Coregonus lavaretus.

Kause A, Quinton C, Airaksinen S, Ruohonen K, Koskela J.

J Anim Sci. 2011 Apr;89(4):959-71. doi: 10.2527/jas.2010-2981. Epub 2010 Nov 19.

PMID:
21097679
47.

Non-invasive measurement of the haemodynamic effects of inhaled salbutamol, intravenous L-arginine and sublingual nitroglycerin.

Tahvanainen A, Leskinen M, Koskela J, Ilveskoski E, Alanko J, Kähönen M, Kööbi T, Lehtimäki L, Moilanen E, Mustonen J, Pörsti I.

Br J Clin Pharmacol. 2009 Jul;68(1):23-33. doi: 10.1111/j.1365-2125.2009.03434.x.

48.

Ageing and cardiovascular responses to head-up tilt in healthy subjects.

Tahvanainen A, Leskinen M, Koskela J, Ilveskoski E, Nordhausen K, Oja H, Kähönen M, Kööbi T, Mustonen J, Pörsti I.

Atherosclerosis. 2009 Dec;207(2):445-51. doi: 10.1016/j.atherosclerosis.2009.06.001. Epub 2009 Jun 11.

PMID:
19580971
49.

Analysis of cardiovascular responses to passive head-up tilt using continuous pulse wave analysis and impedance cardiography.

Tahvanainen A, Koskela J, Tikkakoski A, Lahtela J, Leskinen M, Kähönen M, Nieminen T, Kööbi T, Mustonen J, Pörsti I.

Scand J Clin Lab Invest. 2009;69(1):128-37. doi: 10.1080/00365510802439098.

PMID:
18850486
50.

Genetic potential for the regulation of variability in body lipid and protein content of European whitefish (Coregonus lavaretus).

Kause A, Quinton CD, Ruohonen K, Koskela J.

Br J Nutr. 2009 May;101(10):1444-51. doi: 10.1017/S0007114508091265. Epub 2008 Oct 1.

PMID:
18826727

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