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Items: 1 to 50 of 148

1.

Randomized phase II trial of neoadjuvant everolimus in patients with high-risk localized prostate cancer.

Koshkin VS, Mir MC, Barata P, Gul A, Gupta R, Stephenson AJ, Kaouk J, Berglund R, Magi-Galluzzi C, Klein EA, Dreicer R, Garcia JA.

Invest New Drugs. 2019 Jun;37(3):559-566. doi: 10.1007/s10637-019-00778-4. Epub 2019 Apr 30.

PMID:
31037562
2.

Cytometry of Reaction Rate Constant: Measuring Reaction Rate Constant in Individual Cells To Facilitate Robust and Accurate Analysis of Cell-Population Heterogeneity.

Koshkin V, Kochmann S, Sorupanathan A, Peng C, Ailles LE, Liu G, Krylov SN.

Anal Chem. 2019 Mar 19;91(6):4186-4194. doi: 10.1021/acs.analchem.9b00388. Epub 2019 Mar 4.

PMID:
30829484
3.

Apalutamide in the treatment of castrate-resistant prostate cancer: evidence from clinical trials.

Koshkin VS, Small EJ.

Ther Adv Urol. 2018 Nov 11;10(12):445-454. doi: 10.1177/1756287218811450. eCollection 2018 Dec. Review.

4.

Transcriptomic and Protein Analysis of Small-cell Bladder Cancer (SCBC) Identifies Prognostic Biomarkers and DLL3 as a Relevant Therapeutic Target.

Koshkin VS, Garcia JA, Reynolds J, Elson P, Magi-Galluzzi C, McKenney JK, Isse K, Bishop E, Saunders LR, Balyimez A, Rashid S, Hu M, Stephenson AJ, Fergany AF, Lee BH, Haber GP, Dowlati A, Gilligan T, Ornstein MC, Rini BI, Abazeed ME, Mian OY, Grivas P.

Clin Cancer Res. 2019 Jan 1;25(1):210-221. doi: 10.1158/1078-0432.CCR-18-1278. Epub 2018 Oct 16.

5.

Effect of Switching Systemic Treatment After Stereotactic Radiosurgery for Oligoprogressive, Metastatic Renal Cell Carcinoma.

Barata PC, Mendiratta P, Kotecha R, Gopalakrishnan D, Juloori A, Chao ST, Koshkin V, Ornstein M, Gilligan TD, Wood LS, Rini BI, Angelov L, Garcia JA.

Clin Genitourin Cancer. 2018 Oct;16(5):413-419.e1. doi: 10.1016/j.clgc.2018.07.018. Epub 2018 Aug 17.

PMID:
30172552
6.

Perioperative chemotherapy for muscle-invasive bladder cancer: the importance of multidisciplinary management for evidence-based practice and transformative research.

Koshkin VS, Grivas P.

Transl Androl Urol. 2018 Jun;7(3):504-507. doi: 10.21037/tau.2018.06.03. No abstract available.

7.

HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer.

Alyamani M, Emamekhoo H, Park S, Taylor J, Almassi N, Upadhyay S, Tyler A, Berk MP, Hu B, Hwang TH, Figg WD, Peer CJ, Chien C, Koshkin VS, Mendiratta P, Grivas P, Rini B, Garcia J, Auchus RJ, Sharifi N.

J Clin Invest. 2018 Aug 1;128(8):3333-3340. doi: 10.1172/JCI98319. Epub 2018 Jun 25.

8.

Immune checkpoint inhibitors in urothelial cancer: recent updates and future outlook.

Gopalakrishnan D, Koshkin VS, Ornstein MC, Papatsoris A, Grivas P.

Ther Clin Risk Manag. 2018 Jun 5;14:1019-1040. doi: 10.2147/TCRM.S158753. eCollection 2018. Review.

9.

Treatment selection for men with metastatic prostate cancer who progress on upfront chemo-hormonal therapy.

Barata P, Emamekhoo H, Mendiratta P, Koshkin V, Tyler A, Ornstein M, Rini BI, Gilligan T, Kyriakopoulos C, Garcia JA.

Prostate. 2018 Sep;78(13):1035-1041. doi: 10.1002/pros.23663. Epub 2018 Jun 7.

PMID:
29882332
10.

Emerging Role of Immunotherapy in Advanced Urothelial Carcinoma.

Koshkin VS, Grivas P.

Curr Oncol Rep. 2018 Apr 11;20(6):48. doi: 10.1007/s11912-018-0693-y. Review.

PMID:
29644490
11.

Atezolizumab in Metastatic Urothelial Carcinoma Outside Clinical Trials: Focus on Efficacy, Safety, and Response to Subsequent Therapies.

Barata PC, Gopalakrishnan D, Koshkin VS, Mendiratta P, Karafa M, Allman K, Martin A, Beach J, Profusek P, Tyler A, Wood L, Ornstein M, Gilligan T, Rini BI, Garcia JA, Grivas P.

Target Oncol. 2018 Jun;13(3):353-361. doi: 10.1007/s11523-018-0561-6.

PMID:
29623487
12.

Feasibility of Cisplatin-Based Neoadjuvant Chemotherapy in Muscle-Invasive Bladder Cancer Patients With Diminished Renal Function.

Koshkin VS, Barata PC, Rybicki LA, Zahoor H, Almassi N, Redden AM, Fergany AF, Kaouk J, Haber GP, Stephenson AJ, Ornstein MC, Gilligan T, Garcia JA, Rini BI, Grivas P.

Clin Genitourin Cancer. 2018 Aug;16(4):e879-e892. doi: 10.1016/j.clgc.2018.02.002. Epub 2018 Feb 22.

PMID:
29576445
13.

Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma.

Koshkin VS, Barata PC, Zhang T, George DJ, Atkins MB, Kelly WJ, Vogelzang NJ, Pal SK, Hsu J, Appleman LJ, Ornstein MC, Gilligan T, Grivas P, Garcia JA, Rini BI.

J Immunother Cancer. 2018 Jan 29;6(1):9. doi: 10.1186/s40425-018-0319-9.

14.

Patient Characteristics, Treatment Patterns and Prognostic Factors in Squamous Cell Bladder Cancer.

Zahoor H, Elson P, Stephenson A, Haber GP, Kaouk J, Fergany A, Lee B, Koshkin V, Ornstein M, Gilligan T, Garcia JA, Rini B, Grivas P.

Clin Genitourin Cancer. 2018 Apr;16(2):e437-e442. doi: 10.1016/j.clgc.2017.10.005. Epub 2017 Oct 17.

PMID:
29154041
15.

Next-generation sequencing (NGS) of cell-free circulating tumor DNA and tumor tissue in patients with advanced urothelial cancer: a pilot assessment of concordance.

Barata PC, Koshkin VS, Funchain P, Sohal D, Pritchard A, Klek S, Adamowicz T, Gopalakrishnan D, Garcia J, Rini B, Grivas P.

Ann Oncol. 2017 Oct 1;28(10):2458-2463. doi: 10.1093/annonc/mdx405.

16.

Lack of Effectiveness of Postchemotherapy Lymphadenectomy in Bladder Cancer Patients with Clinical Evidence of Metastatic Pelvic or Retroperitoneal Lymph Nodes Only: A Propensity Score-based Analysis.

Necchi A, Mariani L, Lo Vullo S, Yu EY, Woods ME, Wong YN, Harshman LC, Alva A, Sternberg CN, Bamias A, Grivas P, Koshkin VS, Roghmann F, Dobruch J, Eigl BJ, Nappi L, Milowsky MI, Niegisch G, Pal SK, De Giorgi U, Recine F, Vaishampayan U, Berthold DD, Bowles DW, Baniel J, Theodore C, Ladoire S, Srinivas S, Agarwal N, Crabb S, Sridhar S, Golshayan AR, Ohlmann C, Xylinas E, Powles T, Rosenberg JE, Bellmunt J, van Rhijn B, Galsky MD, Hendricksen K; Young Academic Urologists-Urothelial Carcinoma Group-European Association of Urology and the Retrospective International Study of Invasive/Advanced Cancer of the Urothelium group.

Eur Urol Focus. 2019 Mar;5(2):242-249. doi: 10.1016/j.euf.2017.05.006. Epub 2017 Jun 3.

17.

[Efficacy of walking training in patients with obliterating atherosclerosis of lower limb arteries].

Koshkin VM, Nastavsheva OD, Kalashov PB.

Angiol Sosud Khir. 2017;23(2):25-31. Russian.

PMID:
28594793
18.

Cancer vaccines at the age of immune checkpoint inhibitors: reasonable approach as combination therapy in advanced urothelial carcinoma?

Grivas P, Koshkin VS, Pal SK.

Ann Oncol. 2017 Apr 1;28(4):680-682. doi: 10.1093/annonc/mdx063. No abstract available.

19.

Assessment of Imaging Modalities and Response Metrics in Ewing Sarcoma: Correlation With Survival.

Koshkin VS, Bolejack V, Schwartz LH, Wahl RL, Chugh R, Reinke DK, Zhao B, O JH, Patel SR, Schuetze SM, Baker LH.

J Clin Oncol. 2016 Oct 20;34(30):3680-3685. doi: 10.1200/JCO.2016.68.1858.

20.

Preservation of the 3D Phenotype Upon Dispersal of Cultured Cell Spheroids Into Monolayer Cultures.

Koshkin V, Ailles LE, Liu G, Krylov SN.

J Cell Biochem. 2017 Jan;118(1):154-162. doi: 10.1002/jcb.25621. Epub 2016 Jun 21.

PMID:
27283126
21.

Emerging therapeutics in refractory renal cell carcinoma.

Koshkin VS, Rini BI.

Expert Opin Pharmacother. 2016 Jun;17(9):1225-32. doi: 10.1080/14656566.2016.1182987. Epub 2016 May 23. Review.

PMID:
27112171
22.

Metabolic Suppression of a Drug-Resistant Subpopulation in Cancer Spheroid Cells.

Koshkin V, Ailles LE, Liu G, Krylov SN.

J Cell Biochem. 2016 Jan;117(1):59-65. doi: 10.1002/jcb.25247.

PMID:
26054050
23.

[Detection of genetic determinants that define the difference of near-isogenic Triticum aestivum L. Lines in photoperiodic sensitivity].

Kiseleva AA, Eggi EE, Koshkin VA, Sitnikov MN, Roder M, Salina EA, Potokina EK.

Genetika. 2014 Jul;50(7):802-13. Russian.

PMID:
25720138
24.

[Peculiarities of atherosclerotic lesions of lower limb arteries in patients with type 2 diabetes mellitus].

Koshkina IV, Nastavsheva OD, Sukhorukov EA, Koshkin VM.

Angiol Sosud Khir. 2014;20(3):24-8. Russian.

PMID:
25267221
25.

[Comparative assessment of antiaggregant efficacy of acetylsalicylic acid and clopidogrel in peripheral atherosclerosis].

Kuznetsov MR, Sergeeva NA, Koshkin VM, Boldin BV, Rodionov SV, Virganskiĭ AO, Kosykh IV, Lisenkov OP, Kuznetsova VF.

Angiol Sosud Khir. 2014;20(1):8-14. Russian.

PMID:
24722015
26.

Kinetics of MDR transport in tumor-initiating cells.

Koshkin V, Yang BB, Krylov SN.

PLoS One. 2013 Nov 1;8(11):e79222. doi: 10.1371/journal.pone.0079222. eCollection 2013.

27.

Single-cell-kinetics approach to discover functionally distinct subpopulations within phenotypically uniform populations of cells.

Koshkin V, Krylov SN.

Anal Chem. 2013 Mar 5;85(5):2578-81. doi: 10.1021/ac400151v. Epub 2013 Feb 12.

PMID:
23394374
28.

Correlation between multi-drug resistance-associated membrane transport in clonal cancer cells and the cell cycle phase.

Koshkin V, Krylov SN.

PLoS One. 2012;7(7):e41368. doi: 10.1371/journal.pone.0041368. Epub 2012 Jul 25.

29.

CAD-associated reader error in CT colonography.

Koshkin VS, Hinshaw JL, Wroblewski K, Dachman AH.

Acad Radiol. 2012 Jul;19(7):801-10. doi: 10.1016/j.acra.2012.03.008. Epub 2012 Apr 24.

PMID:
22537502
30.

Mechanistic studies on the application of DNA aptamers as inhibitors of 2-oxoglutarate-dependent oxygenases.

Krylova SM, Koshkin V, Bagg E, Schofield CJ, Krylov SN.

J Med Chem. 2012 Apr 12;55(7):3546-52. doi: 10.1021/jm300243h. Epub 2012 Apr 3.

31.

Beta-cell uncoupling protein 2 regulates reactive oxygen species production, which influences both insulin and glucagon secretion.

Robson-Doucette CA, Sultan S, Allister EM, Wikstrom JD, Koshkin V, Bhattacharjee A, Prentice KJ, Sereda SB, Shirihai OS, Wheeler MB.

Diabetes. 2011 Nov;60(11):2710-9. doi: 10.2337/db11-0132. Epub 2011 Oct 7.

32.

[Role of low-dose acetylsalicylic acid in comprehensive postoperative treatment of patients with lower-limb chronic arterial insufficiency].

Kuznetsov MR, Rodionov SV, Koshkin VM, Virganskiĭ AO, Golosnitskiĭ PIu, Tepliakov SA, Kosykh IV, Ostapchuk NA, Lisenkov OP, Chernikov VP.

Angiol Sosud Khir. 2011;17(2):23-9. Russian.

PMID:
21983458
33.

Single-cell-kinetics approach to compare multidrug resistance-associated membrane transport in subpopulations of cells.

Koshkin V, Krylov SN.

Anal Chem. 2011 Aug 15;83(16):6132-4. doi: 10.1021/ac201690t. Epub 2011 Jul 22.

PMID:
21770449
34.

Beta cell-specific Znt8 deletion in mice causes marked defects in insulin processing, crystallisation and secretion.

Wijesekara N, Dai FF, Hardy AB, Giglou PR, Bhattacharjee A, Koshkin V, Chimienti F, Gaisano HY, Rutter GA, Wheeler MB.

Diabetologia. 2010 Aug;53(8):1656-68. doi: 10.1007/s00125-010-1733-9. Epub 2010 Apr 28.

35.
36.

Molecular and metabolic evidence for mitochondrial defects associated with beta-cell dysfunction in a mouse model of type 2 diabetes.

Lu H, Koshkin V, Allister EM, Gyulkhandanyan AV, Wheeler MB.

Diabetes. 2010 Feb;59(2):448-59. doi: 10.2337/db09-0129. Epub 2009 Nov 10.

37.

Insulin storage and glucose homeostasis in mice null for the granule zinc transporter ZnT8 and studies of the type 2 diabetes-associated variants.

Nicolson TJ, Bellomo EA, Wijesekara N, Loder MK, Baldwin JM, Gyulkhandanyan AV, Koshkin V, Tarasov AI, Carzaniga R, Kronenberger K, Taneja TK, da Silva Xavier G, Libert S, Froguel P, Scharfmann R, Stetsyuk V, Ravassard P, Parker H, Gribble FM, Reimann F, Sladek R, Hughes SJ, Johnson PR, Masseboeuf M, Burcelin R, Baldwin SA, Liu M, Lara-Lemus R, Arvan P, Schuit FC, Wheeler MB, Chimienti F, Rutter GA.

Diabetes. 2009 Sep;58(9):2070-83. doi: 10.2337/db09-0551. Epub 2009 Jun 19.

38.

[Peculiarities of peripheral haemodynamics in patients with varicose disease of lower-limb veins complicated by trophic ulcers].

Koshkin VM, Karalkin AV, Nastavsheva OD, Bogdanets LI, Girina MB, Siniakov KI.

Angiol Sosud Khir. 2008;14(2):79-83. Russian.

PMID:
19156055
39.

[Prediction of remote results after surgical management of patients presenting with atherosclerosis obliterans of the lower-limb arteries].

Kuznetsov MR, Boldin BV, Koshkin VM, Rodionov SV, Turkin PIu, Khaitov MR, Vorontsov VM, Pinegin BV.

Angiol Sosud Khir. 2008;14(1):106-12. Russian.

PMID:
19156038
40.

UCP2 is highly expressed in pancreatic alpha-cells and influences secretion and survival.

Diao J, Allister EM, Koshkin V, Lee SC, Bhattacharjee A, Tang C, Giacca A, Chan CB, Wheeler MB.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):12057-62. doi: 10.1073/pnas.0710434105. Epub 2008 Aug 13.

41.

Limited mitochondrial permeabilization is an early manifestation of palmitate-induced lipotoxicity in pancreatic beta-cells.

Koshkin V, Dai FF, Robson-Doucette CA, Chan CB, Wheeler MB.

J Biol Chem. 2008 Mar 21;283(12):7936-48. Epub 2007 Dec 26.

42.

[Functional flowmetry in determining the indications for reconstructive surgical interventions on the major arteries of the pelvis and lower limbs].

Kuznetsov MR, Koshkin VM, Rodionov SV, Virganskiĭ AO, Moskalenko EP, Golosnitskiĭ PY, Dobrianskiĭ MV.

Angiol Sosud Khir. 2006;12(4):127-32. Russian.

PMID:
17679966
43.

[Antioxidant and metabolic therapy of lower limb chronic obliterative arterial disease].

Koshkin VM, Murav'ev SV, Dadova LV, Kalashov PB.

Angiol Sosud Khir. 2006;12(3):29-32. Review. Russian.

PMID:
17641611
44.

alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells.

Targonsky ED, Dai F, Koshkin V, Karaman GT, Gyulkhandanyan AV, Zhang Y, Chan CB, Wheeler MB.

Diabetologia. 2006 Jul;49(7):1587-98. Epub 2006 May 13.

PMID:
16752177
45.
46.

Caspase-mediated cell death predominates following engraftment of neural progenitor cells into traumatically injured rat brain.

Bakshi A, Keck CA, Koshkin VS, LeBold DG, Siman R, Snyder EY, McIntosh TK.

Brain Res. 2005 Dec 14;1065(1-2):8-19. Epub 2005 Nov 23.

PMID:
16309635
47.

[Conservative treatment of lower limb chronic obliterative atherosclerosis: strategy and tactics].

Koshkin VM, Stoĭko IuM.

Angiol Sosud Khir. 2005;11(1):132-5. Russian.

PMID:
16034335
48.

[Preoperative care of microcirculatory vessels in patients with lower limb arteriosclerosis obliterans].

Kuznetsov MR, Koshkin VM, Karalkin AV, Boldin BV, Rodionov SV, Sergeeva NA, Petukhov EB, Golosnitskiĭ PIu.

Angiol Sosud Khir. 2005;11(1):19-24. Russian.

PMID:
16034319
49.
50.

[Morphological characterization of arteriovenous shunts in the lower limbs].

Zimin VR, Charyeva IG, Pylaev AS, Koshkin VM.

Angiol Sosud Khir. 2004;10(4):31-3. Russian.

PMID:
15627132

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