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Items: 8

1.

Novel Lysine-Based Thioureas as Mechanism-Based Inhibitors of Sirtuin 2 (SIRT2) with Anticancer Activity in a Colorectal Cancer Murine Model.

Farooqi AS, Hong JY, Cao J, Lu X, Price IR, Zhao Q, Kosciuk T, Yang M, Bai JJ, Lin H.

J Med Chem. 2019 Apr 25;62(8):4131-4141. doi: 10.1021/acs.jmedchem.9b00191. Epub 2019 Apr 15.

PMID:
30986062
2.

Updates on the epigenetic roles of sirtuins.

Kosciuk T, Wang M, Hong JY, Lin H.

Curr Opin Chem Biol. 2019 Aug;51:18-29. doi: 10.1016/j.cbpa.2019.01.023. Epub 2019 Mar 12. Review.

PMID:
30875552
3.

MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer.

Oudin MJ, Barbier L, Schäfer C, Kosciuk T, Miller MA, Han S, Jonas O, Lauffenburger DA, Gertler FB.

Mol Cancer Ther. 2017 Jan;16(1):143-155. doi: 10.1158/1535-7163.MCT-16-0413. Epub 2016 Nov 3.

4.

MenaINV mediates synergistic cross-talk between signaling pathways driving chemotaxis and haptotaxis.

Oudin MJ, Miller MA, Klazen JA, Kosciuk T, Lussiez A, Hughes SK, Tadros J, Bear JE, Lauffenburger DA, Gertler FB.

Mol Biol Cell. 2016 Oct 15;27(20):3085-3094. Epub 2016 Aug 24.

5.

Parallel In Vivo Assessment of Drug Phenotypes at Various Time Points during Systemic BRAF Inhibition Reveals Tumor Adaptation and Altered Treatment Vulnerabilities.

Jonas O, Oudin MJ, Kosciuk T, Whitman M, Gertler FB, Cima MJ, Flaherty KT, Langer R.

Clin Cancer Res. 2016 Dec 15;22(24):6031-6038. Epub 2016 Apr 18.

6.

Tumor Cell-Driven Extracellular Matrix Remodeling Drives Haptotaxis during Metastatic Progression.

Oudin MJ, Jonas O, Kosciuk T, Broye LC, Guido BC, Wyckoff J, Riquelme D, Lamar JM, Asokan SB, Whittaker C, Ma D, Langer R, Cima MJ, Wisinski KB, Hynes RO, Lauffenburger DA, Keely PJ, Bear JE, Gertler FB.

Cancer Discov. 2016 May;6(5):516-31. doi: 10.1158/2159-8290.CD-15-1183. Epub 2016 Jan 25.

7.

Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis.

Han XH, Jin YR, Tan L, Kosciuk T, Lee JS, Yoon JK.

Mol Cell Biol. 2014 Feb;34(4):752-64. doi: 10.1128/MCB.01285-13. Epub 2013 Dec 16.

8.

Influence of some anthropometric parameters on the risk of development of distal complications after mastectomy carried out because of breast carcinoma.

Kopanski Z, Wojewoda T, Wojewoda A, Schlegel-Zawadzka M, Wozniacka R, Suder A, Kosciuk T.

Am J Hum Biol. 2003 May-Jun;15(3):433-9.

PMID:
12704719

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