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Items: 1 to 50 of 70

1.

Multiple chronic conditions: Implications for cognition - Findings from the Wisconsin Registry for Alzheimer's Prevention (WRAP).

Bratzke LC, Carlson BA, Moon C, Brown RL, Koscik RL, Johnson SC.

Appl Nurs Res. 2018 Aug;42:56-61. doi: 10.1016/j.apnr.2018.06.004. Epub 2018 Jun 18.

PMID:
30029715
2.

The recency ratio as predictor of early MCI.

Bruno D, Koscik RL, Woodard JL, Pomara N, Johnson SC.

Int Psychogeriatr. 2018 Apr 18:1-6. doi: 10.1017/S1041610218000467. [Epub ahead of print]

PMID:
29667564
3.

Moderate intensity physical activity associates with CSF biomarkers in a cohort at risk for Alzheimer's disease.

Law LL, Rol RN, Schultz SA, Dougherty RJ, Edwards DF, Koscik RL, Gallagher CL, Carlsson CM, Bendlin BB, Zetterberg H, Blennow K, Asthana S, Sager MA, Hermann BP, Johnson SC, Cook DB, Okonkwo OC.

Alzheimers Dement (Amst). 2018 Feb 6;10:188-195. doi: 10.1016/j.dadm.2018.01.001. eCollection 2018.

4.

Age-accelerated cognitive decline in asymptomatic adults with CSF β-amyloid.

Clark LR, Berman SE, Norton D, Koscik RL, Jonaitis E, Blennow K, Bendlin BB, Asthana S, Johnson SC, Zetterberg H, Carlsson CM.

Neurology. 2018 Apr 10;90(15):e1306-e1315. doi: 10.1212/WNL.0000000000005291. Epub 2018 Mar 9.

PMID:
29523644
5.

Cognitive decline in the middle-aged after surgery and anaesthesia: results from the Wisconsin Registry for Alzheimer's Prevention cohort.

Bratzke LC, Koscik RL, Schenning KJ, Clark LR, Sager MA, Johnson SC, Hermann BP, Hogan KJ.

Anaesthesia. 2018 May;73(5):549-555. doi: 10.1111/anae.14216. Epub 2018 Feb 21.

PMID:
29468634
6.

The effect of rare variants in TREM2 and PLD3 on longitudinal cognitive function in the Wisconsin Registry for Alzheimer's Prevention.

Engelman CD, Darst BF, Bilgel M, Vasiljevic E, Koscik RL, Jedynak BM, Johnson SC.

Neurobiol Aging. 2018 Jun;66:177.e1-177.e5. doi: 10.1016/j.neurobiolaging.2017.12.025. Epub 2017 Dec 29.

PMID:
29395285
7.

Declines in Connected Language Are Associated with Very Early Mild Cognitive Impairment: Results from the Wisconsin Registry for Alzheimer's Prevention.

Mueller KD, Koscik RL, Hermann BP, Johnson SC, Turkstra LS.

Front Aging Neurosci. 2018 Jan 9;9:437. doi: 10.3389/fnagi.2017.00437. eCollection 2017.

8.

The Wisconsin Registry for Alzheimer's Prevention: A review of findings and current directions.

Johnson SC, Koscik RL, Jonaitis EM, Clark LR, Mueller KD, Berman SE, Bendlin BB, Engelman CD, Okonkwo OC, Hogan KJ, Asthana S, Carlsson CM, Hermann BP, Sager MA.

Alzheimers Dement (Amst). 2017 Dec 8;10:130-142. doi: 10.1016/j.dadm.2017.11.007. eCollection 2018. Review.

9.

Social support and verbal interaction are differentially associated with cognitive function in midlife and older age.

Zuelsdorff ML, Koscik RL, Okonkwo OC, Peppard PE, Hermann BP, Sager MA, Johnson SC, Engelman CD.

Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2017 Dec 15:1-17. doi: 10.1080/13825585.2017.1414769. [Epub ahead of print]

PMID:
29241403
10.

The Latent Structure and Test-Retest Stability of Connected Language Measures in the Wisconsin Registry for Alzheimer's Prevention (WRAP).

Mueller KD, Koscik RL, Clark LR, Hermann BP, Johnson SC, Turkstra LS.

Arch Clin Neuropsychol. 2017 Nov 24:1-13. doi: 10.1093/arclin/acx116. [Epub ahead of print]

PMID:
29186313
11.

Cognitive Variability Predicts Incident Alzheimer's Disease and Mild Cognitive Impairment Comparable to a Cerebrospinal Fluid Biomarker.

Gleason CE, Norton D, Anderson ED, Wahoske M, Washington DT, Umucu E, Koscik RL, Dowling NM, Johnson SC, Carlsson CM, Asthana S; Alzheimer’s Disease Neuroimaging Initiative.

J Alzheimers Dis. 2018;61(1):79-89. doi: 10.3233/JAD-170498.

PMID:
29125485
12.

Vascular, inflammatory, and metabolic factors associated with cognition in aging persons with chronic epilepsy.

Hermann BP, Sager MA, Koscik RL, Young K, Nakamura K.

Epilepsia. 2017 Nov;58(11):e152-e156. doi: 10.1111/epi.13891. Epub 2017 Sep 4.

PMID:
28872189
13.

Use of the Quick Dementia Rating System (QDRS) as an Initial Screening Measure in a Longitudinal Cohort at Risk for Alzheimer's Disease.

Berman SE, Koscik RL, Clark LR, Mueller KD, Bluder L, Galvin JE, Johnson SC.

J Alzheimers Dis Rep. 2017;1(1):9-13. doi: 10.3233/ADR-170004. Epub 2017 Apr 28.

14.

Temporal Order of Alzheimer's Disease-Related Cognitive Marker Changes in BLSA and WRAP Longitudinal Studies.

Bilgel M, Koscik RL, An Y, Prince JL, Resnick SM, Johnson SC, Jedynak BM.

J Alzheimers Dis. 2017;59(4):1335-1347. doi: 10.3233/JAD-170448.

15.

Longitudinal Assessment of Self- and Informant-Subjective Cognitive Complaints in a Sample of Healthy Late-Middle Aged Adults Enriched with a Family History of Alzheimer's Disease.

Nicholas CR, Dowling NM, Racine AM, Clark LR, Berman SE, Koscik RL, Asthana S, Hermann B, Sager MA, Johnson SC.

J Int Neuropsychol Soc. 2017 Sep;23(8):617-626. doi: 10.1017/S1355617717000509. Epub 2017 Jul 11.

PMID:
28693655
16.

Poor sleep is associated with CSF biomarkers of amyloid pathology in cognitively normal adults.

Sprecher KE, Koscik RL, Carlsson CM, Zetterberg H, Blennow K, Okonkwo OC, Sager MA, Asthana S, Johnson SC, Benca RM, Bendlin BB.

Neurology. 2017 Aug 1;89(5):445-453. doi: 10.1212/WNL.0000000000004171. Epub 2017 Jul 5.

17.

Association of longitudinal white matter degeneration and cerebrospinal fluid biomarkers of neurodegeneration, inflammation and Alzheimer's disease in late-middle-aged adults.

Racine AM, Merluzzi AP, Adluru N, Norton D, Koscik RL, Clark LR, Berman SE, Nicholas CR, Asthana S, Alexander AL, Blennow K, Zetterberg H, Kim WH, Singh V, Carlsson CM, Bendlin BB, Johnson SC.

Brain Imaging Behav. 2017 Jun 9. doi: 10.1007/s11682-017-9732-9. [Epub ahead of print]

PMID:
28600739
18.

Reliability of a Novel Social Activity Questionnaire: Perceived Social Support and Verbal Interaction in the Wisconsin Registry for Alzheimer's Prevention.

Zuelsdorff ML, Koscik RL, Okonkwo OC, Peppard PE, Hermann BP, Sager MA, Johnson SC, Engelman CD.

J Aging Health. 2018 Feb;30(2):305-320. doi: 10.1177/0898264316674812. Epub 2016 Oct 24.

19.

Family history and TOMM40 '523 interactive associations with memory in middle-aged and Alzheimer's disease cohorts.

Willette AA, Webb JL, Lutz MW, Bendlin BB, Wennberg AM, Oh JM, Roses A, Koscik RL, Hermann BP, Dowling NM, Asthana S, Johnson SC; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement. 2017 Nov;13(11):1217-1225. doi: 10.1016/j.jalz.2017.03.009. Epub 2017 May 23.

PMID:
28549947
20.

BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer's Prevention.

Boots EA, Schultz SA, Clark LR, Racine AM, Darst BF, Koscik RL, Carlsson CM, Gallagher CL, Hogan KJ, Bendlin BB, Asthana S, Sager MA, Hermann BP, Christian BT, Dubal DB, Engelman CD, Johnson SC, Okonkwo OC.

Neurology. 2017 May 30;88(22):2098-2106. doi: 10.1212/WNL.0000000000003980. Epub 2017 May 3.

21.

Positive affect predicts cerebral glucose metabolism in late middle-aged adults.

Nicholas CR, Hoscheidt SM, Clark LR, Racine AM, Berman SE, Koscik RL, Maritza Dowling N, Asthana S, Christian BT, Sager MA, Johnson SC.

Soc Cogn Affect Neurosci. 2017 Jun 1;12(6):993-1000. doi: 10.1093/scan/nsx027.

22.

Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD.

Schultz SA, Boots EA, Darst BF, Zetterberg H, Blennow K, Edwards DF, Koscik RL, Carlsson CM, Gallagher CL, Bendlin BB, Asthana S, Sager MA, Hogan KJ, Hermann BP, Cook DB, Johnson SC, Engelman CD, Okonkwo OC.

Neurology. 2017 Apr 25;88(17):1650-1658. doi: 10.1212/WNL.0000000000003862. Epub 2017 Mar 24.

23.

Relationships between cardiorespiratory fitness, hippocampal volume, and episodic memory in a population at risk for Alzheimer's disease.

Dougherty RJ, Schultz SA, Boots EA, Ellingson LD, Meyer JD, Van Riper S, Stegner AJ, Edwards DF, Oh JM, Einerson J, Korcarz CE, Koscik RL, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, Asthana S, Hermann BP, Sager MA, Stein JH, Johnson SC, Okonkwo OC, Cook DB.

Brain Behav. 2017 Feb 17;7(3):e00625. doi: 10.1002/brb3.625. eCollection 2017 Mar.

24.

Chronotropic Response and Cognitive Function in a Cohort at Risk for Alzheimer's Disease.

Law LL, Schultz SA, Boots EA, Einerson JA, Dougherty RJ, Oh JM, Korcarz CE, Edwards DF, Koscik RL, Dowling NM, Gallagher CL, Bendlin BB, Carlsson CM, Asthana S, Hermann BP, Sager MA, Johnson SC, Cook DB, Stein JH, Okonkwo OC.

J Alzheimers Dis. 2017;56(1):351-359. doi: 10.3233/JAD-160642.

25.

Intraindividual Cognitive Variability in Middle Age Predicts Cognitive Impairment 8-10 Years Later: Results from the Wisconsin Registry for Alzheimer's Prevention.

Koscik RL, Berman SE, Clark LR, Mueller KD, Okonkwo OC, Gleason CE, Hermann BP, Sager MA, Johnson SC.

J Int Neuropsychol Soc. 2016 Nov;22(10):1016-1025.

26.

Connected Language in Late Middle-Aged Adults at Risk for Alzheimer's Disease.

Mueller KD, Koscik RL, Turkstra LS, Riedeman SK, LaRue A, Clark LR, Hermann B, Sager MA, Johnson SC.

J Alzheimers Dis. 2016 Oct 18;54(4):1539-1550.

27.

Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer's Disease.

Racine AM, Clark LR, Berman SE, Koscik RL, Mueller KD, Norton D, Nicholas CR, Blennow K, Zetterberg H, Jedynak B, Bilgel M, Carlsson CM, Christian BT, Asthana S, Johnson SC.

J Alzheimers Dis. 2016 Oct 18;54(4):1395-1408.

28.

Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer's Disease.

Darst BF, Koscik RL, Racine AM, Oh JM, Krause RA, Carlsson CM, Zetterberg H, Blennow K, Christian BT, Bendlin BB, Okonkwo OC, Hogan KJ, Hermann BP, Sager MA, Asthana S, Johnson SC, Engelman CD.

J Alzheimers Dis. 2017;55(2):473-484.

29.

Cognitive variability-A marker for incident MCI and AD: An analysis for the Alzheimer's Disease Neuroimaging Initiative.

Anderson ED, Wahoske M, Huber M, Norton D, Li Z, Koscik RL, Umucu E, Johnson SC, Jones J, Asthana S, Gleason CE; Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement (Amst). 2016 May 26;4:47-55. doi: 10.1016/j.dadm.2016.05.003. eCollection 2016.

30.

Meeting physical activity recommendations may be protective against temporal lobe atrophy in older adults at risk for Alzheimer's disease.

Dougherty RJ, Ellingson LD, Schultz SA, Boots EA, Meyer JD, Lindheimer JB, Van Riper S, Stegner AJ, Edwards DF, Oh JM, Koscik RL, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, Asthana S, Hermann BP, Sager MA, Johnson SC, Okonkwo OC, Cook DB.

Alzheimers Dement (Amst). 2016 Apr 9;4:14-7. doi: 10.1016/j.dadm.2016.03.005. eCollection 2016.

31.

Biomarker clusters are differentially associated with longitudinal cognitive decline in late midlife.

Racine AM, Koscik RL, Berman SE, Nicholas CR, Clark LR, Okonkwo OC, Rowley HA, Asthana S, Bendlin BB, Blennow K, Zetterberg H, Gleason CE, Carlsson CM, Johnson SC.

Brain. 2016 Aug;139(Pt 8):2261-74. doi: 10.1093/brain/aww142. Epub 2016 Jun 20.

32.

Mild Cognitive Impairment in Late Middle Age in the Wisconsin Registry for Alzheimer's Prevention Study: Prevalence and Characteristics Using Robust and Standard Neuropsychological Normative Data.

Clark LR, Koscik RL, Nicholas CR, Okonkwo OC, Engelman CD, Bratzke LC, Hogan KJ, Mueller KD, Bendlin BB, Carlsson CM, Asthana S, Sager MA, Hermann BP, Johnson SC.

Arch Clin Neuropsychol. 2016 May 8. pii: acw024. [Epub ahead of print]

33.

Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation.

Racine AM, Koscik RL, Nicholas CR, Clark LR, Okonkwo OC, Oh JM, Hillmer AT, Murali D, Barnhart TE, Betthauser TJ, Gallagher CL, Rowley HA, Dowling NM, Asthana S, Bendlin BB, Blennow K, Zetterberg H, Carlsson CM, Christian BT, Johnson SC.

Alzheimers Dement (Amst). 2016;2:27-38.

34.

Beta-amyloid and cognitive decline in late middle age: Findings from the Wisconsin Registry for Alzheimer's Prevention study.

Clark LR, Racine AM, Koscik RL, Okonkwo OC, Engelman CD, Carlsson CM, Asthana S, Bendlin BB, Chappell R, Nicholas CR, Rowley HA, Oh JM, Hermann BP, Sager MA, Christian BT, Johnson SC.

Alzheimers Dement. 2016 Jul;12(7):805-14. doi: 10.1016/j.jalz.2015.12.009. Epub 2016 Jan 21.

35.

Cardiorespiratory Fitness Attenuates the Influence of Amyloid on Cognition.

Schultz SA, Boots EA, Almeida RP, Oh JM, Einerson J, Korcarz CE, Edwards DF, Koscik RL, Dowling MN, Gallagher CL, Bendlin BB, Christian BT, Zetterberg H, Blennow K, Carlsson CM, Asthana S, Hermann BP, Sager MA, Johnson SC, Stein JH, Okonkwo OC.

J Int Neuropsychol Soc. 2015 Nov;21(10):841-50. doi: 10.1017/S1355617715000843.

36.

Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease.

Willette AA, Bendlin BB, Starks EJ, Birdsill AC, Johnson SC, Christian BT, Okonkwo OC, La Rue A, Hermann BP, Koscik RL, Jonaitis EM, Sager MA, Asthana S.

JAMA Neurol. 2015 Sep;72(9):1013-20. doi: 10.1001/jamaneurol.2015.0613. Erratum in: JAMA Neurol. 2015 Dec;72(12):1537.

37.

Amyloid burden, cortical thickness, and cognitive function in the Wisconsin Registry for Alzheimer's Prevention.

Doherty BM, Schultz SA, Oh JM, Koscik RL, Dowling NM, Barnhart TE, Murali D, Gallagher CL, Carlsson CM, Bendlin BB, LaRue A, Hermann BP, Rowley HA, Asthana S, Sager MA, Christian BT, Johnson SC, Okonkwo OC.

Alzheimers Dement (Amst). 2015 Jun 1;1(2):160-169.

38.

Occupational Complexity and Cognitive Reserve in a Middle-Aged Cohort at Risk for Alzheimer's Disease.

Boots EA, Schultz SA, Almeida RP, Oh JM, Koscik RL, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, Asthana S, Sager MA, Hermann BP, Johnson SC, Okonkwo OC.

Arch Clin Neuropsychol. 2015 Nov;30(7):634-42. doi: 10.1093/arclin/acv041. Epub 2015 Jul 8.

39.

Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults.

Sprecher KE, Bendlin BB, Racine AM, Okonkwo OC, Christian BT, Koscik RL, Sager MA, Asthana S, Johnson SC, Benca RM.

Neurobiol Aging. 2015 Sep;36(9):2568-76. doi: 10.1016/j.neurobiolaging.2015.05.004. Epub 2015 May 14.

40.

Verbal Fluency and Early Memory Decline: Results from the Wisconsin Registry for Alzheimer's Prevention.

Mueller KD, Koscik RL, LaRue A, Clark LR, Hermann B, Johnson SC, Sager MA.

Arch Clin Neuropsychol. 2015 Aug;30(5):448-57. doi: 10.1093/arclin/acv030. Epub 2015 May 29.

41.

Aging, Practice Effects, and Genetic Risk in the Wisconsin Registry for Alzheimer's Prevention.

Jonaitis EM, Koscik RL, La Rue A, Johnson SC, Hermann BP, Sager MA.

Clin Neuropsychol. 2015;29(4):426-41. doi: 10.1080/13854046.2015.1047407. Epub 2015 May 27.

42.

Subjective memory complaints, cortical thinning, and cognitive dysfunction in middle-aged adults at risk for AD.

Schultz SA, Oh JM, Koscik RL, Dowling NM, Gallagher CL, Carlsson CM, Bendlin BB, LaRue A, Hermann BP, Rowley HA, Asthana S, Sager MA, Johnson SC, Okonkwo OC.

Alzheimers Dement (Amst). 2015 Mar 1;1(1):33-40.

43.

Heritability of cognitive traits among siblings with a parental history of Alzheimer's disease.

Darst BF, Koscik RL, Hermann BP, La Rue A, Sager MA, Johnson SC, Engelman CD.

J Alzheimers Dis. 2015;45(4):1149-55. doi: 10.3233/JAD-142658.

44.

Long Term Outcomes of a Curriculum on Care for the Underserved.

Cox ED, Koscik RL, Behrmann AT, Young HN, Moreno MA, McIntosh GC, Kokotailo PK.

J Natl Med Assoc. 2015 Feb;107(1):17-25. doi: 10.1016/S0027-9684(15)30005-5. Epub 2015 Dec 2.

PMID:
27282524
45.

Cardiorespiratory fitness is associated with brain structure, cognition, and mood in a middle-aged cohort at risk for Alzheimer's disease.

Boots EA, Schultz SA, Oh JM, Larson J, Edwards D, Cook D, Koscik RL, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, LaRue A, Asthana S, Hermann BP, Sager MA, Johnson SC, Okonkwo OC.

Brain Imaging Behav. 2015 Sep;9(3):639-49. doi: 10.1007/s11682-014-9325-9.

46.

Insulin resistance predicts brain amyloid deposition in late middle-aged adults.

Willette AA, Johnson SC, Birdsill AC, Sager MA, Christian B, Baker LD, Craft S, Oh J, Statz E, Hermann BP, Jonaitis EM, Koscik RL, La Rue A, Asthana S, Bendlin BB.

Alzheimers Dement. 2015 May;11(5):504-510.e1. doi: 10.1016/j.jalz.2014.03.011. Epub 2014 Jul 17.

47.

Emergence of mild cognitive impairment in late middle-aged adults in the wisconsin registry for Alzheimer's prevention.

Koscik RL, La Rue A, Jonaitis EM, Okonkwo OC, Johnson SC, Bendlin BB, Hermann BP, Sager MA.

Dement Geriatr Cogn Disord. 2014;38(1-2):16-30. doi: 10.1159/000355682. Epub 2014 Feb 20.

48.

Investigation of triggering receptor expressed on myeloid cells 2 variant in the Wisconsin Registry for Alzheimer's Prevention.

Engelman CD, Koscik RL, Jonaitis EM, Hermann BP, La Rue A, Sager MA.

Neurobiol Aging. 2014 Jun;35(6):1252-4. doi: 10.1016/j.neurobiolaging.2013.11.013. Epub 2013 Nov 20.

49.

Cognitive activities and cognitive performance in middle-aged adults at risk for Alzheimer's disease.

Jonaitis E, La Rue A, Mueller KD, Koscik RL, Hermann B, Sager MA.

Psychol Aging. 2013 Dec;28(4):1004-14. doi: 10.1037/a0034838.

50.

Regional white matter hyperintensities: aging, Alzheimer's disease risk, and cognitive function.

Birdsill AC, Koscik RL, Jonaitis EM, Johnson SC, Okonkwo OC, Hermann BP, Larue A, Sager MA, Bendlin BB.

Neurobiol Aging. 2014 Apr;35(4):769-76. doi: 10.1016/j.neurobiolaging.2013.10.072. Epub 2013 Oct 10.

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