Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 51

1.

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes.

Grünvogel O, Colasanti O, Lee JY, Klöss V, Belouzard S, Reustle A, Esser-Nobis K, Hesebeck-Brinckmann J, Mutz P, Hoffmann K, Mehrabi A, Koschny R, Vondran FWR, Gotthardt D, Schnitzler P, Neumann-Haefelin C, Thimme R, Binder M, Bartenschlager R, Dubuisson J, Dalpke AH, Lohmann V.

Gastroenterology. 2018 Jun;154(8):2237-2251.e16. doi: 10.1053/j.gastro.2018.03.020. Epub 2018 Mar 11.

2.

Hyalinosis cutis et mucosae: eine klinische Fallvorstellung mit besonderer Berücksichtigung von Schleimhautveränderungen.

Epple A, Hoxha E, Schneiderbauer R, Jappel A, Koschny R, Enk A, Haenssle HA.

J Dtsch Dermatol Ges. 2018 Feb;16(2):210-212. doi: 10.1111/ddg.13416_g. No abstract available.

PMID:
29418097
3.

HBV Bypasses the Innate Immune Response and Does Not Protect HCV From Antiviral Activity of Interferon.

Mutz P, Metz P, Lempp FA, Bender S, Qu B, Schöneweis K, Seitz S, Tu T, Restuccia A, Frankish J, Dächert C, Schusser B, Koschny R, Polychronidis G, Schemmer P, Hoffmann K, Baumert TF, Binder M, Urban S, Bartenschlager R.

Gastroenterology. 2018 May;154(6):1791-1804.e22. doi: 10.1053/j.gastro.2018.01.044. Epub 2018 Feb 1.

4.

Hyalinosis cutis et mucosae: A clinical investigation with special regard to mucosal changes.

Epple A, Hoxha E, Schneiderbauer R, Jappel A, Koschny R, Enk A, Haenssle HA.

J Dtsch Dermatol Ges. 2018 Feb;16(2):211-213. doi: 10.1111/ddg.13416. Epub 2018 Jan 16. No abstract available.

PMID:
29337435
5.

Extracorporeal life support and digoxin-specific Fab fragments for successful management of Taxus baccata intoxication with low output and ventricular arrhythmia.

Farag M, Badowski D, Koschny R, Skopp G, Brcic A, Szabo GB.

Am J Emerg Med. 2017 Dec;35(12):1987.e3-1987.e7. doi: 10.1016/j.ajem.2017.09.031. Epub 2017 Sep 18.

PMID:
28941873
6.

Sorafenib in Patients with Hepatocellular Carcinoma-Results of the Observational INSIGHT Study.

Ganten TM, Stauber RE, Schott E, Malfertheiner P, Buder R, Galle PR, Göhler T, Walther M, Koschny R, Gerken G.

Clin Cancer Res. 2017 Oct 1;23(19):5720-5728. doi: 10.1158/1078-0432.CCR-16-0919. Epub 2017 Jul 11.

PMID:
28698202
7.

Pancreatic Atrophy in Hepatocellular Carcinoma Patients Receiving Long-Term Treatment with Sorafenib.

Ganten MK, Schuessler M, Bruckner T, Ganten TM, Koschny R.

Oncology. 2015;89(2):88-94. doi: 10.1159/000377681. Epub 2015 Apr 2.

PMID:
25871578
8.

Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis.

von Karstedt S, Conti A, Nobis M, Montinaro A, Hartwig T, Lemke J, Legler K, Annewanter F, Campbell AD, Taraborrelli L, Grosse-Wilde A, Coy JF, El-Bahrawy MA, Bergmann F, Koschny R, Werner J, Ganten TM, Schweiger T, Hoetzenecker K, Kenessey I, Hegedüs B, Bergmann M, Hauser C, Egberts JH, Becker T, Röcken C, Kalthoff H, Trauzold A, Anderson KI, Sansom OJ, Walczak H.

Cancer Cell. 2015 Apr 13;27(4):561-73. doi: 10.1016/j.ccell.2015.02.014. Epub 2015 Apr 2.

9.

[Gastrointestinal stromal tumours (GIST)--development in pathology, surgery and medical therapy. Developed during the 10th German GIST-meeting, Göttingen].

Agaimy A, Bauer S, Beham A, Bertolini J, Haller F, Koschny R, Maier J, Montemurro M, Perez D, Schaefer IM, Schildhaus HU, Wurst C, Cameron S.

Z Gastroenterol. 2015 Mar;53(3):235-43. doi: 10.1055/s-0034-1385711. Epub 2015 Mar 16. German.

PMID:
25775172
10.

WHO grade related expression of TRAIL-receptors and apoptosis regulators in meningioma.

Koschny R, Krupp W, Xu LX, Mueller WC, Bauer M, Sinn P, Keller M, Koschny T, Walczak H, Bruckner T, Ganten TM, Holland H.

Pathol Res Pract. 2015 Feb;211(2):109-16. doi: 10.1016/j.prp.2014.11.002. Epub 2014 Nov 13.

PMID:
25481563
11.

Three gangliogliomas: results of GTG-banding, SKY, genome-wide high resolution SNP-array, gene expression and review of the literature.

Xu LX, Holland H, Kirsten H, Ahnert P, Krupp W, Bauer M, Schober R, Mueller W, Fritzsch D, Meixensberger J, Koschny R.

Neuropathology. 2015 Apr;35(2):148-57. doi: 10.1111/neup.12176. Epub 2014 Nov 6. Review.

PMID:
25376146
12.

Bortezomib sensitizes primary meningioma cells to TRAIL-induced apoptosis by enhancing formation of the death-inducing signaling complex.

Koschny R, Boehm C, Sprick MR, Haas TL, Holland H, Xu LX, Krupp W, Mueller WC, Bauer M, Koschny T, Keller M, Sinn P, Meixensberger J, Walczak H, Ganten TM.

J Neuropathol Exp Neurol. 2014 Nov;73(11):1034-46. doi: 10.1097/NEN.0000000000000129.

PMID:
25289891
13.

Extracorporeal life support and plasmapheresis in a case of severe polyintoxication.

Koschny R, Lutz M, Seckinger J, Schwenger V, Stremmel W, Eisenbach C.

J Emerg Med. 2014 Nov;47(5):527-31. doi: 10.1016/j.jemermed.2014.04.044. Epub 2014 Sep 12.

PMID:
25220022
14.

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E.

Cancer Discov. 2014 Jun;4(6):730-43. doi: 10.1158/2159-8290.CD-13-0782. Epub 2014 Mar 31.

15.

Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection.

Brost S, Zimmermann A, Koschny R, Sykora J, Stremmel W, Schirmacher P, Walczak H, Ganten TM.

Pathol Res Pract. 2014 Feb;210(2):83-91. doi: 10.1016/j.prp.2013.10.005. Epub 2013 Nov 7.

PMID:
24268735
16.

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma.

Koschny R, Brost S, Hinz U, Sykora J, Batke EM, Singer S, Breuhahn K, Stremmel W, Walczak H, Schemmer P, Schirmacher P, Ganten TM.

BMC Cancer. 2013 Nov 9;13:532. doi: 10.1186/1471-2407-13-532.

17.

Development of miliary tuberculosis under infliximab in a patient with spondyloarthritis and suspected Crohn's disease.

Koschny R, Junghanss T, Mischnik A, Karner M, Kreuter M, Roth W, Stremmel W, Merle U.

Z Gastroenterol. 2013 Oct;51(10):1177-83. doi: 10.1055/s-0033-1350372. Epub 2013 Oct 11.

PMID:
24122379
18.

Sorafenib treatment is save and may affect survival of recurrent hepatocellular carcinoma after liver transplantation.

Pfeiffenberger J, Koschny R, Hoffmann K, Mehrabi A, Schmitz A, Radeleff B, Stremmel W, Schemmer P, Ganten TM.

Langenbecks Arch Surg. 2013 Dec;398(8):1123-8. doi: 10.1007/s00423-013-1114-1. Epub 2013 Oct 4.

PMID:
24091908
19.

Comprehensive high-resolution genomic profiling and cytogenetics of two pediatric and one adult medulloblastoma.

Holland H, Xu LX, Ahnert P, Kirsten H, Koschny R, Bauer M, Schober R, Meixensberger J, Krupp W.

Pathol Res Pract. 2013 Sep;209(9):541-7. doi: 10.1016/j.prp.2013.06.001. Epub 2013 Jul 4.

PMID:
23896263
20.

Fatal course of a suicidal intoxication with hydrochloric Acid.

Koschny R, Herceg M, Stremmel W, Eisenbach C.

Case Rep Gastroenterol. 2013 Jan;7(1):89-96. doi: 10.1159/000350189. Epub 2013 Mar 7.

21.

Diarrhea is a positive outcome predictor for sorafenib treatment of advanced hepatocellular carcinoma.

Koschny R, Gotthardt D, Koehler C, Jaeger D, Stremmel W, Ganten TM.

Oncology. 2013;84(1):6-13. doi: 10.1159/000342425. Epub 2012 Oct 13.

PMID:
23075905
22.

Loss of endothelial thrombomodulin predicts response to steroid therapy and survival in acute intestinal graft-versus-host disease.

Andrulis M, Dietrich S, Longerich T, Koschny R, Burian M, Schmitt-Gräf A, Schirmacher P, Ho AD, Dreger P, Luft T.

Haematologica. 2012 Nov;97(11):1674-7. doi: 10.3324/haematol.2011.061051. Epub 2012 Jun 11.

23.

Detection of novel genomic aberrations in anaplastic astrocytomas by GTG-banding, SKY, locus-specific FISH, and high density SNP-array.

Holland H, Ahnert P, Koschny R, Kirsten H, Bauer M, Schober R, Meixensberger J, Fritzsch D, Krupp W.

Pathol Res Pract. 2012 Jun 15;208(6):325-30. doi: 10.1016/j.prp.2012.03.010. Epub 2012 May 8.

PMID:
22575435
24.

High resolution genomic profiling and classical cytogenetics in a group of benign and atypical meningiomas.

Holland H, Mocker K, Ahnert P, Kirsten H, Hantmann H, Koschny R, Bauer M, Schober R, Scholz M, Meixensberger J, Krupp W.

Cancer Genet. 2011 Oct;204(10):541-9. doi: 10.1016/j.cancergen.2011.10.007.

PMID:
22137484
25.

Pulmonary, rhino-orbital and cutaneous mucormycosis caused by Rhizomucor pusillus in an immunocompromised patient.

Hadaschik E, Koschny R, Willinger B, Hallscheidt P, Enk A, Hartschuh W.

Clin Exp Dermatol. 2012 Jun;37(4):355-7. doi: 10.1111/j.1365-2230.2011.04235.x. Epub 2011 Nov 21.

PMID:
22103628
26.

Intracranial hemangiopericytoma: Case study with cytogenetics and genome wide SNP-A analysis.

Holland H, Livrea M, Ahnert P, Koschny R, Kirsten H, Meixensberger J, Bauer M, Schober R, Fritzsch D, Krupp W.

Pathol Res Pract. 2011 May 15;207(5):310-6. doi: 10.1016/j.prp.2010.12.010. Epub 2011 Feb 9.

PMID:
21306833
27.

hERG K+ channel-associated cardiac effects of the antidepressant drug desipramine.

Staudacher I, Wang L, Wan X, Obers S, Wenzel W, Tristram F, Koschny R, Staudacher K, Kisselbach J, Koelsch P, Schweizer PA, Katus HA, Ficker E, Thomas D.

Naunyn Schmiedebergs Arch Pharmacol. 2011 Feb;383(2):119-39. doi: 10.1007/s00210-010-0583-9. Epub 2010 Dec 1.

PMID:
21120454
28.

Multiple meningioma with different grades of malignancy: case report with genetic analysis applying single-nucleotide polymorphism array and classical cytogenetics.

Mocker K, Holland H, Ahnert P, Schober R, Bauer M, Kirsten H, Koschny R, Meixensberger J, Krupp W.

Pathol Res Pract. 2011 Jan 15;207(1):67-72. doi: 10.1016/j.prp.2010.09.001.

PMID:
20926204
29.

WHO grade-specific comparative genomic hybridization pattern of astrocytoma - a meta-analysis.

Holland H, Koschny T, Ahnert P, Meixensberger J, Koschny R.

Pathol Res Pract. 2010 Oct 15;206(10):663-8. doi: 10.1016/j.prp.2010.04.002. Epub 2010 Jun 1.

PMID:
20570053
30.

Multiple mechanisms of hERG liability: K+ current inhibition, disruption of protein trafficking, and apoptosis induced by amoxapine.

Obers S, Staudacher I, Ficker E, Dennis A, Koschny R, Erdal H, Bloehs R, Kisselbach J, Karle CA, Schweizer PA, Katus HA, Thomas D.

Naunyn Schmiedebergs Arch Pharmacol. 2010 May;381(5):385-400. doi: 10.1007/s00210-010-0496-7. Epub 2010 Mar 13.

PMID:
20229012
31.

Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction.

Haas TL, Emmerich CH, Gerlach B, Schmukle AC, Cordier SM, Rieser E, Feltham R, Vince J, Warnken U, Wenger T, Koschny R, Komander D, Silke J, Walczak H.

Mol Cell. 2009 Dec 11;36(5):831-44. doi: 10.1016/j.molcel.2009.10.013.

32.

Beyond Milan criteria--chances and risks of expanding transplantation criteria for HCC patients with liver cirrhosis.

Koschny R, Schmidt J, Ganten TM.

Clin Transplant. 2009 Dec;23 Suppl 21:49-60. doi: 10.1111/j.1399-0012.2009.01110.x. Review.

PMID:
19930317
33.

Differential expression of the TRAIL/TRAIL-receptor system in patients with inflammatory bowel disease.

Brost S, Koschny R, Sykora J, Stremmel W, Lasitschka F, Walczak H, Ganten TM.

Pathol Res Pract. 2010 Jan 15;206(1):43-50. doi: 10.1016/j.prp.2009.09.005. Epub 2009 Dec 1.

PMID:
19954896
34.

Bortezomib sensitizes primary human esthesioneuroblastoma cells to TRAIL-induced apoptosis.

Koschny R, Holland H, Sykora J, Erdal H, Krupp W, Bauer M, Bockmuehl U, Ahnert P, Meixensberger J, Stremmel W, Walczak H, Ganten TM.

J Neurooncol. 2010 Apr;97(2):171-85. doi: 10.1007/s11060-009-0010-6. Epub 2009 Sep 20.

PMID:
19768634
35.

TRAIL and other TRAIL receptor agonists as novel cancer therapeutics.

Falschlehner C, Ganten TM, Koschny R, Schaefer U, Walczak H.

Adv Exp Med Biol. 2009;647:195-206. doi: 10.1007/978-0-387-89520-8_14. Review.

PMID:
19760076
36.

Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer.

Ganten TM, Sykora J, Koschny R, Batke E, Aulmann S, Mansmann U, Stremmel W, Sinn HP, Walczak H.

J Mol Med (Berl). 2009 Oct;87(10):995-1007. doi: 10.1007/s00109-009-0510-z. Epub 2009 Aug 13.

PMID:
19680616
37.

Assessment of neuropsychological parameters and quality of life to evaluate outcome in patients with surgically treated supratentorial meningiomas.

Krupp W, Klein C, Koschny R, Holland H, Seifert V, Meixensberger J.

Neurosurgery. 2009 Jan;64(1):40-7; discussion 47. doi: 10.1227/01.NEU.0000336330.75381.39.

PMID:
19145155
38.

Genome-wide genetic characterization of an atypical meningioma by single-nucleotide polymorphism array-based mapping and classical cytogenetics.

Krupp W, Holland H, Koschny R, Bauer M, Schober R, Kirsten H, Livrea M, Meixensberger J, Ahnert P.

Cancer Genet Cytogenet. 2008 Jul 15;184(2):87-93. doi: 10.1016/j.cancergencyto.2008.03.015.

PMID:
18617056
39.

Doxazosin induces apoptosis of cells expressing hERG K+ channels.

Thomas D, Bloehs R, Koschny R, Ficker E, Sykora J, Kiehn J, Schlömer K, Gierten J, Kathöfer S, Zitron E, Scholz EP, Kiesecker C, Katus HA, Karle CA.

Eur J Pharmacol. 2008 Jan 28;579(1-3):98-103. Epub 2007 Dec 4.

40.

Cytogenetic and molecular biological characterization of an adult medulloblastoma.

Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Schober R, Kirsten H, Ganten TM, Ahnert P.

Cancer Genet Cytogenet. 2007 Oct 15;178(2):104-13.

PMID:
17954265
41.

Bortezomib sensitizes primary human astrocytoma cells of WHO grades I to IV for tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis.

Koschny R, Holland H, Sykora J, Haas TL, Sprick MR, Ganten TM, Krupp W, Bauer M, Ahnert P, Meixensberger J, Walczak H.

Clin Cancer Res. 2007 Jun 1;13(11):3403-12.

42.

The promise of TRAIL--potential and risks of a novel anticancer therapy.

Koschny R, Walczak H, Ganten TM.

J Mol Med (Berl). 2007 Sep;85(9):923-35. Epub 2007 Apr 17. Review.

PMID:
17437073
43.

TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer-specific apoptosis within a therapeutic window.

Koschny R, Ganten TM, Sykora J, Haas TL, Sprick MR, Kolb A, Stremmel W, Walczak H.

Hepatology. 2007 Mar;45(3):649-58.

PMID:
17326159
44.

Comprehensive cytogenetic characterization of an esthesioneuroblastoma.

Holland H, Koschny R, Krupp W, Meixensberger J, Bauer M, Kirsten H, Ahnert P.

Cancer Genet Cytogenet. 2007 Mar;173(2):89-96.

PMID:
17321323
45.

Helicobacter pylori-induced apoptosis in T cells is mediated by the mitochondrial pathway independent of death receptors.

Ganten TM, Aravena E, Sykora J, Koschny R, Mohr J, Rudi J, Stremmel W, Walczak H.

Eur J Clin Invest. 2007 Feb;37(2):117-25.

PMID:
17217377
46.

Preclinical differentiation between apparently safe and potentially hepatotoxic applications of TRAIL either alone or in combination with chemotherapeutic drugs.

Ganten TM, Koschny R, Sykora J, Schulze-Bergkamen H, Büchler P, Haas TL, Schader MB, Untergasser A, Stremmel W, Walczak H.

Clin Cancer Res. 2006 Apr 15;12(8):2640-6.

47.

Comparative genomic hybridization pattern of non-anaplastic and anaplastic oligodendrogliomas--a meta-analysis.

Koschny R, Holland H, Koschny T, Vitzthum HE.

Pathol Res Pract. 2006;202(1):23-30. Epub 2005 Dec 13.

PMID:
16356658
48.

Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL.

Ganten TM, Koschny R, Haas TL, Sykora J, Li-Weber M, Herzer K, Walczak H.

Hepatology. 2005 Sep;42(3):588-97.

PMID:
16037944
49.

Transforming growth factor beta can mediate apoptosis via the expression of TRAIL in human hepatoma cells.

Herzer K, Ganten TM, Schulze-Bergkamen H, Grosse-Wilde A, Koschny R, Krammer PH, Walczak H.

Hepatology. 2005 Jul;42(1):183-92.

PMID:
15962328
50.

Gain of chromosome 7 detected by comparative genomic hybridization accumulates with age in patients with glioblastoma multiforme.

Zuber MA, Koschny R, Koschny T, Froster UG.

Cancer Genet Cytogenet. 2002 Jul 1;136(1):92-4. No abstract available.

PMID:
12165461

Supplemental Content

Loading ...
Support Center