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Items: 37

1.

Prolonged survival in a patient with a cervical spine H3K27M-mutant diffuse midline glioma.

Peters K, Pratt D, Koschmann C, Leung D.

BMJ Case Rep. 2019 Oct 17;12(10). pii: e231424. doi: 10.1136/bcr-2019-231424.

PMID:
31628092
2.

Recurrent non-canonical histone H3 mutations in spinal cord diffuse gliomas.

Sloan EA, Cooney T, Oberheim Bush NA, Buerki R, Taylor J, Clarke JL, Torkildson J, Kline C, Reddy A, Mueller S, Banerjee A, Butowski N, Chang S, Mummaneni PV, Chou D, Tan L, Theodosopoulos P, McDermott M, Berger M, Raffel C, Gupta N, Sun PP, Li Y, Shah V, Cha S, Braunstein S, Raleigh DR, Samuel D, Scharnhorst D, Fata C, Guo H, Moes G, Kim JYH, Koschmann C, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Phillips JJ, Tihan T, Bollen AW, Perry A, Solomon DA.

Acta Neuropathol. 2019 Nov;138(5):877-881. doi: 10.1007/s00401-019-02072-2. Epub 2019 Sep 12. No abstract available.

PMID:
31515627
3.

Successful treatment of a TSC2-mutant glioblastoma with everolimus.

Zureick AH, McFadden KA, Mody R, Koschmann C.

BMJ Case Rep. 2019 May 31;12(5). pii: e227734. doi: 10.1136/bcr-2018-227734.

PMID:
31154346
4.

Integrating subgroups with mixed-type endpoints in early phase oncology trials.

Zhao L, Koschmann C.

Stat Methods Med Res. 2019 Apr 4:962280219840050. doi: 10.1177/0962280219840050. [Epub ahead of print]

PMID:
30945609
5.

Pediatric craniopharyngioma in association with familial adenomatous polyposis.

Dahl NA, Pratt D, Camelo-Piragua S, Kumar-Sinha C, Mody RJ, Septer S, Hankinson TC, Chinnaiyan AM, Koschmann C, Hoffman L.

Fam Cancer. 2019 Jul;18(3):327-330. doi: 10.1007/s10689-019-00126-8.

PMID:
30919136
6.

Multiplatform Molecular Profiling: A Precision Medicine Victory Built on Cytotoxic Chemotherapy.

Cantor E, Koschmann C.

Cancer J. 2019 Mar/Apr;25(2):80. doi: 10.1097/PPO.0000000000000359. No abstract available.

PMID:
30896527
7.

Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations.

Miklja Z, Pasternak A, Stallard S, Nicolaides T, Kline-Nunnally C, Cole B, Beroukhim R, Bandopadhayay P, Chi S, Ramkissoon SH, Mullan B, Bruzek AK, Gauthier A, Garcia T, Atchison C, Marini B, Fouladi M, Parsons DW, Leary S, Mueller S, Ligon KL, Koschmann C.

Neuro Oncol. 2019 Feb 26. pii: noz022. doi: 10.1093/neuonc/noz022. [Epub ahead of print]

PMID:
30805642
8.

IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response.

Núñez FJ, Mendez FM, Kadiyala P, Alghamri MS, Savelieff MG, Garcia-Fabiani MB, Haase S, Koschmann C, Calinescu AA, Kamran N, Saxena M, Patel R, Carney S, Guo MZ, Edwards M, Ljungman M, Qin T, Sartor MA, Tagett R, Venneti S, Brosnan-Cashman J, Meeker A, Gorbunova V, Zhao L, Kremer DM, Zhang L, Lyssiotis CA, Jones L, Herting CJ, Ross JL, Hambardzumyan D, Hervey-Jumper S, Figueroa ME, Lowenstein PR, Castro MG.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaaq1427. doi: 10.1126/scitranslmed.aaq1427.

9.

Erratum: Author Correction: Identification and targeting of an FGFR fusion in a pediatric thalamic "central oligodendroglioma".

Linzey JR, Marini B, McFadden K, Lorenzana A, Mody R, Robertson PL, Koschmann C.

NPJ Precis Oncol. 2018 Apr 25;2:12. doi: 10.1038/s41698-018-0054-1. eCollection 2018.

10.

CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response.

Stallard S, Savelieff MG, Wierzbicki K, Mullan B, Miklja Z, Bruzek A, Garcia T, Siada R, Anderson B, Singer BH, Hashizume R, Carcaboso AM, McMurray KQ, Heth J, Muraszko K, Robertson PL, Mody R, Venneti S, Garton H, Koschmann C.

Acta Neuropathol Commun. 2018 Aug 15;6(1):80. doi: 10.1186/s40478-018-0580-7. No abstract available.

11.

Medulloblastoma therapy generates risk of a poorly-prognostic H3 wild-type subgroup of diffuse intrinsic pontine glioma: a report from the International DIPG Registry.

Gits HC, Anderson M, Stallard S, Pratt D, Zon B, Howell C, Kumar-Sinha C, Vats P, Kasaian K, Polan D, Matuszak M, Spratt DE, Leonard M, Qin T, Zhao L, Leach J, Chaney B, Escorza NY, Hendershot J, Jones B, Fuller C, Leary S, Bartels U, Bouffet E, Yock TI, Robertson P, Mody R, Venneti S, Chinnaiyan AM, Fouladi M, Gottardo NG, Koschmann C.

Acta Neuropathol Commun. 2018 Jul 26;6(1):67. doi: 10.1186/s40478-018-0570-9.

12.

Multi-focal sequencing of a diffuse intrinsic pontine glioma establishes PTEN loss as an early event.

Koschmann C, Farooqui Z, Kasaian K, Cao X, Zamler D, Stallard S, Venneti S, Hervey-Jumper S, Garton H, Muraszko K, Franchi L, Robertson PL, Leonard M, Opipari V, Castro MG, Lowenstein PR, Chinnaiyan A, Mody R.

NPJ Precis Oncol. 2017 Sep 14;1(1):32. doi: 10.1038/s41698-017-0033-y. eCollection 2017.

13.

Identification and targeting of an FGFR fusion in a pediatric thalamic "central oligodendroglioma".

Linzey JR, Marini B, McFadden K, Lorenzana A, Mody R, Robertson PL, Koschmann C.

NPJ Precis Oncol. 2017 Sep 7;1(1):29. doi: 10.1038/s41698-017-0036-8. eCollection 2017. Erratum in: NPJ Precis Oncol. 2018 Apr 25;2:12.

14.

Molecular ablation of tumor blood vessels inhibits therapeutic effects of radiation and bevacizumab.

Yadav VN, Altshuler D, Kadiyala P, Zamler D, Comba A, Appelman H, Dunn P, Koschmann C, Castro MG, Löwenstein PR.

Neuro Oncol. 2018 Sep 3;20(10):1356-1367. doi: 10.1093/neuonc/noy055.

15.

BRAF activating mutations involving the β3-αC loop in V600E-negative anaplastic pleomorphic xanthoastrocytoma.

Pratt D, Camelo-Piragua S, McFadden K, Leung D, Mody R, Chinnaiyan A, Koschmann C, Venneti S.

Acta Neuropathol Commun. 2018 Mar 15;6(1):24. doi: 10.1186/s40478-018-0525-1. No abstract available.

16.

Circumscribed/non-diffuse histology confers a better prognosis in H3K27M-mutant gliomas.

Pratt D, Natarajan SK, Banda A, Giannini C, Vats P, Koschmann C, Mody R, Chinnaiyan A, Venneti S.

Acta Neuropathol. 2018 Feb;135(2):299-301. doi: 10.1007/s00401-018-1805-3. Epub 2018 Jan 4. No abstract available.

17.

Development of the CNS TAP tool for the selection of precision medicine therapies in neuro-oncology.

Linzey JR, Marini BL, Pasternak A, Smith C, Miklja Z, Zhao L, Kumar-Sinha C, Paul A, Harris N, Robertson PL, Hoffman LM, Chinnaiyan A, Mody R, Koschmann C.

J Neurooncol. 2018 Mar;137(1):155-169. doi: 10.1007/s11060-017-2708-1. Epub 2017 Dec 12.

18.

Blood-brain barrier-adapted precision medicine therapy for pediatric brain tumors.

Marini BL, Benitez LL, Zureick AH, Salloum R, Gauthier AC, Brown J, Wu YM, Robinson DR, Kumar C, Lonigro R, Vats P, Cao X, Kasaian K, Anderson B, Mullan B, Chandler B, Linzey JR, Camelo-Piragua SI, Venneti S, McKeever PE, McFadden KA, Lieberman AP, Brown N, Shao L, Leonard MAS, Junck L, McKean E, Maher CO, Garton HJL, Muraszko KM, Hervey-Jumper S, Mulcahy-Levy JM, Green A, Hoffman LM, Dorris K, Vitanza NA, Wang J, Schwartz J, Lulla R, Smiley NP, Bornhorst M, Haas-Kogan DA, Robertson PL, Chinnaiyan AM, Mody R, Koschmann C.

Transl Res. 2017 Oct;188:27.e1-27.e14. doi: 10.1016/j.trsl.2017.08.001. Epub 2017 Aug 10.

19.

Clinical Application of Whole Genome Array Improves the Diagnosis of Pediatric Brain Tumors.

Shao L, Miller S, Koschmann C, Camelo-Piragua S.

Int J Surg Pathol. 2017 Dec;25(8):688-695. doi: 10.1177/1066896917727349. Epub 2017 Aug 27.

PMID:
28844173
20.

Integrating RNA sequencing into neuro-oncology practice.

Rogawski DS, Vitanza NA, Gauthier AC, Ramaswamy V, Koschmann C.

Transl Res. 2017 Nov;189:93-104. doi: 10.1016/j.trsl.2017.06.013. Epub 2017 Jul 8. Review.

21.

Loss of CDKN1C in a Recurrent Atypical Teratoid/Rhabdoid Tumor.

Tran D, Camelo-Piragua S, Gupta A, Gowans K, Robertson PL, Mody R, Koschmann C.

J Pediatr Hematol Oncol. 2017 Nov;39(8):e466-e469. doi: 10.1097/MPH.0000000000000873.

22.

Single vs. combination immunotherapeutic strategies for glioma.

Chandran M, Candolfi M, Shah D, Mineharu Y, Yadav VN, Koschmann C, Asad AS, Lowenstein PR, Castro MG.

Expert Opin Biol Ther. 2017 May;17(5):543-554. doi: 10.1080/14712598.2017.1305353. Epub 2017 Mar 20. Review.

23.

Mutated Chromatin Regulatory Factors as Tumor Drivers in Cancer.

Koschmann C, Nunez FJ, Mendez F, Brosnan-Cashman JA, Meeker AK, Lowenstein PR, Castro MG.

Cancer Res. 2017 Jan 15;77(2):227-233. doi: 10.1158/0008-5472.CAN-16-2301. Epub 2017 Jan 6. Review.

24.

Molecular characterization reveals NF1 deletions and FGFR1-activating mutations in a pediatric spinal oligodendroglioma.

Bruzek AK, Zureick AH, McKeever PE, Garton HJL, Robertson PL, Mody R, Koschmann CJ.

Pediatr Blood Cancer. 2017 Jun;64(6). doi: 10.1002/pbc.26346. Epub 2016 Nov 10.

25.

Brainstem Low-Grade Gliomas in Children-Excellent Outcomes With Multimodality Therapy.

Upadhyaya SA, Koschmann C, Muraszko K, Venneti S, Garton HJ, Hamstra DA, Maher CO, Betz BL, Brown NA, Wahl D, Weigelin HC, DuRoss KE, Leonard AS, Robertson PL.

J Child Neurol. 2017 Feb;32(2):194-203. doi: 10.1177/0883073816675547. Epub 2016 Nov 3.

26.

Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma.

Koschmann C, Zamler D, MacKay A, Robinson D, Wu YM, Doherty R, Marini B, Tran D, Garton H, Muraszko K, Robertson P, Leonard M, Zhao L, Bixby D, Peterson L, Camelo-Piragua S, Jones C, Mody R, Lowenstein PR, Castro MG.

Oncotarget. 2016 Oct 4;7(40):65696-65706. doi: 10.18632/oncotarget.11602.

27.

Recent advances and future of immunotherapy for glioblastoma.

Kamran N, Calinescu A, Candolfi M, Chandran M, Mineharu Y, Asad AS, Koschmann C, Nunez FJ, Lowenstein PR, Castro MG.

Expert Opin Biol Ther. 2016 Oct;16(10):1245-64. doi: 10.1080/14712598.2016.1212012. Epub 2016 Jul 27. Review.

28.

ATRX mutations and glioblastoma: Impaired DNA damage repair, alternative lengthening of telomeres, and genetic instability.

Koschmann C, Lowenstein PR, Castro MG.

Mol Cell Oncol. 2016 Apr 27;3(3):e1167158. doi: 10.1080/23723556.2016.1167158. eCollection 2016 May.

29.

ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma.

Koschmann C, Calinescu AA, Nunez FJ, Mackay A, Fazal-Salom J, Thomas D, Mendez F, Kamran N, Dzaman M, Mulpuri L, Krasinkiewicz J, Doherty R, Lemons R, Brosnan-Cashman JA, Li Y, Roh S, Zhao L, Appelman H, Ferguson D, Gorbunova V, Meeker A, Jones C, Lowenstein PR, Castro MG.

Sci Transl Med. 2016 Mar 2;8(328):328ra28. doi: 10.1126/scitranslmed.aac8228.

30.

Survival After Relapse of Medulloblastoma.

Koschmann C, Bloom K, Upadhyaya S, Geyer JR, Leary SE.

J Pediatr Hematol Oncol. 2016 May;38(4):269-73. doi: 10.1097/MPH.0000000000000547.

PMID:
26907655
31.

Transposon mediated integration of plasmid DNA into the subventricular zone of neonatal mice to generate novel models of glioblastoma.

Calinescu AA, Núñez FJ, Koschmann C, Kolb BL, Lowenstein PR, Castro MG.

J Vis Exp. 2015 Feb 22;(96). doi: 10.3791/52443.

32.

Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic therapy.

Baker GJ, Yadav VN, Motsch S, Koschmann C, Calinescu AA, Mineharu Y, Camelo-Piragua SI, Orringer D, Bannykh S, Nichols WS, deCarvalho AC, Mikkelsen T, Castro MG, Lowenstein PR.

Neoplasia. 2014 Jul;16(7):543-61. doi: 10.1016/j.neo.2014.06.003.

33.

Adenoviral vector-mediated gene therapy for gliomas: coming of age.

Castro MG, Candolfi M, Wilson TJ, Calinescu A, Paran C, Kamran N, Koschmann C, Moreno-Ayala MA, Assi H, Lowenstein PR.

Expert Opin Biol Ther. 2014 Sep;14(9):1241-57. doi: 10.1517/14712598.2014.915307. Epub 2014 Apr 29. Review.

34.

Lentiviral-induced high-grade gliomas in rats: the effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H.

Lynes J, Wibowo M, Koschmann C, Baker GJ, Saxena V, Muhammad AK, Bondale N, Klein J, Assi H, Lieberman AP, Castro MG, Lowenstein PR.

Neurotherapeutics. 2014 Jul;11(3):623-35. doi: 10.1007/s13311-014-0269-y.

35.

No evidence of a trial effect in newly diagnosed pediatric acute lymphoblastic leukemia.

Koschmann C, Thomson B, Hawkins DS.

Arch Pediatr Adolesc Med. 2010 Mar;164(3):214-7. doi: 10.1001/archpediatrics.2009.282.

PMID:
20194252
36.

Multistate outbreak of Escherichia coli O157:H7 infection associated with consumption of packaged spinach, August-September 2006: the Wisconsin investigation.

Wendel AM, Johnson DH, Sharapov U, Grant J, Archer JR, Monson T, Koschmann C, Davis JP.

Clin Infect Dis. 2009 Apr 15;48(8):1079-86. doi: 10.1086/597399.

PMID:
19265476

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