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Items: 1 to 50 of 55

1.

Parkin-mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes.

Koyano F, Yamano K, Kosako H, Kimura Y, Kimura M, Fujiki Y, Tanaka K, Matsuda N.

EMBO Rep. 2019 Oct 10:e47728. doi: 10.15252/embr.201947728. [Epub ahead of print]

2.

Structural Basis of Mitochondrial Scaffolds by Prohibitin Complexes: Insight into a Role of the Coiled-Coil Region.

Yoshinaka T, Kosako H, Yoshizumi T, Furukawa R, Hirano Y, Kuge O, Tamada T, Koshiba T.

iScience. 2019 Sep 27;19:1065-1078. doi: 10.1016/j.isci.2019.08.056. Epub 2019 Sep 3.

3.

Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL.

Koyano F, Yamano K, Kosako H, Tanaka K, Matsuda N.

J Biol Chem. 2019 Jun 28;294(26):10300-10314. doi: 10.1074/jbc.RA118.006302. Epub 2019 May 20.

4.

Activation of unliganded FGF receptor by extracellular phosphate potentiates proteolytic protection of FGF23 by its O-glycosylation.

Takashi Y, Kosako H, Sawatsubashi S, Kinoshita Y, Ito N, Tsoumpra MK, Nangaku M, Abe M, Matsuhisa M, Kato S, Matsumoto T, Fukumoto S.

Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11418-11427. doi: 10.1073/pnas.1815166116. Epub 2019 May 16.

5.

[Cytomegalovirus meningoencephalitis in a diffuse large B-cell lymphoma patient undergoing salvage chemotherapy].

Yoshida K, Kosako H, Yamashita Y, Kobata H, Oiwa T, Hosoi H, Murata S, Mushino T, Nishikawa A, Araoka H, Sonoki T, Tamura S.

Rinsho Ketsueki. 2019;60(2):124-129. doi: 10.11406/rinketsu.60.124. Japanese.

PMID:
30842379
6.

Phosphorylation-mediated activation of mouse Xkr8 scramblase for phosphatidylserine exposure.

Sakuragi T, Kosako H, Nagata S.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):2907-2912. doi: 10.1073/pnas.1820499116. Epub 2019 Feb 4.

7.

Phosphoproteomic identification and functional characterization of protein kinase substrates by 2D-DIGE and Phos-tag PAGE.

Motani K, Kosako H.

Biochim Biophys Acta Proteins Proteom. 2019 Jan;1867(1):57-61. doi: 10.1016/j.bbapap.2018.06.002. Epub 2018 Jun 5. Review.

PMID:
29883688
8.

Baicalein disturbs the morphological plasticity and motility of breast adenocarcinoma cells depending on the tumor microenvironment.

Terabayashi T, Hanada K, Motani K, Kosako H, Yamaoka M, Kimura T, Ishizaki T.

Genes Cells. 2018 Jun;23(6):466-479. doi: 10.1111/gtc.12584. Epub 2018 Apr 7.

9.

Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D.

Motani K, Kosako H.

J Biol Chem. 2018 May 18;293(20):7717-7726. doi: 10.1074/jbc.RA118.002175. Epub 2018 Apr 4.

10.

The autophagy receptor ALLO-1 and the IKKE-1 kinase control clearance of paternal mitochondria in Caenorhabditis elegans.

Sato M, Sato K, Tomura K, Kosako H, Sato K.

Nat Cell Biol. 2018 Jan;20(1):81-91. doi: 10.1038/s41556-017-0008-9. Epub 2017 Dec 18.

PMID:
29255173
11.

Global Identification of ERK Substrates by Phosphoproteomics Based on IMAC and 2D-DIGE.

Kosako H, Motani K.

Methods Mol Biol. 2017;1487:137-149.

PMID:
27924564
12.

Protein kinase D regulates positive selection of CD4+ thymocytes through phosphorylation of SHP-1.

Ishikawa E, Kosako H, Yasuda T, Ohmuraya M, Araki K, Kurosaki T, Saito T, Yamasaki S.

Nat Commun. 2016 Sep 27;7:12756. doi: 10.1038/ncomms12756.

13.

PKA Regulates PINK1 Stability and Parkin Recruitment to Damaged Mitochondria through Phosphorylation of MIC60.

Akabane S, Uno M, Tani N, Shimazaki S, Ebara N, Kato H, Kosako H, Oka T.

Mol Cell. 2016 May 5;62(3):371-384. doi: 10.1016/j.molcel.2016.03.037.

14.

Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.

Shindo Y, Iwamoto K, Mouri K, Hibino K, Tomita M, Kosako H, Sako Y, Takahashi K.

Nat Commun. 2016 Jan 20;7:10485. doi: 10.1038/ncomms10485.

15.

[Proteomic analyses reveal regulation of the nuclear pore complex by post-translational modifications].

Kosako H.

Seikagaku. 2015 Feb;87(1):49-55. Review. Japanese. No abstract available.

PMID:
26571555
16.

Phosphorylated ubiquitin chain is the genuine Parkin receptor.

Okatsu K, Koyano F, Kimura M, Kosako H, Saeki Y, Tanaka K, Matsuda N.

J Cell Biol. 2015 Apr 13;209(1):111-28. doi: 10.1083/jcb.201410050. Epub 2015 Apr 6.

17.

Ubiquitin is phosphorylated by PINK1 to activate parkin.

Koyano F, Okatsu K, Kosako H, Tamura Y, Go E, Kimura M, Kimura Y, Tsuchiya H, Yoshihara H, Hirokawa T, Endo T, Fon EA, Trempe JF, Saeki Y, Tanaka K, Matsuda N.

Nature. 2014 Jun 5;510(7503):162-6. doi: 10.1038/nature13392. Epub 2014 Jun 4.

PMID:
24784582
18.

Epithelial protein lost in neoplasm modulates platelet-derived growth factor-mediated adhesion and motility of mesangial cells.

Tsurumi H, Harita Y, Kurihara H, Kosako H, Hayashi K, Matsunaga A, Kajiho Y, Kanda S, Miura K, Sekine T, Oka A, Ishizuka K, Horita S, Hattori M, Hattori S, Igarashi T.

Kidney Int. 2014 Sep;86(3):548-57. doi: 10.1038/ki.2014.85. Epub 2014 Apr 2.

19.

Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.

Iguchi M, Kujuro Y, Okatsu K, Koyano F, Kosako H, Kimura M, Suzuki N, Uchiyama S, Tanaka K, Matsuda N.

J Biol Chem. 2013 Jul 26;288(30):22019-32. doi: 10.1074/jbc.M113.467530. Epub 2013 Jun 10.

20.

GRK6 deficiency in mice causes autoimmune disease due to impaired apoptotic cell clearance.

Nakaya M, Tajima M, Kosako H, Nakaya T, Hashimoto A, Watari K, Nishihara H, Ohba M, Komiya S, Tani N, Nishida M, Taniguchi H, Sato Y, Matsumoto M, Tsuda M, Kuroda M, Inoue K, Kurose H.

Nat Commun. 2013;4:1532. doi: 10.1038/ncomms2540.

21.

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria.

Okatsu K, Oka T, Iguchi M, Imamura K, Kosako H, Tani N, Kimura M, Go E, Koyano F, Funayama M, Shiba-Fukushima K, Sato S, Shimizu H, Fukunaga Y, Taniguchi H, Komatsu M, Hattori N, Mihara K, Tanaka K, Matsuda N.

Nat Commun. 2012;3:1016. doi: 10.1038/ncomms2016.

22.

[Global analysis of protein kinase substrates using phosphoproteomic techniques].

Kosako H.

Seikagaku. 2011 Dec;83(12):1122-7. Review. Japanese. No abstract available.

PMID:
22352043
23.

Quantitative phosphoproteomics strategies for understanding protein kinase-mediated signal transduction pathways.

Kosako H, Nagano K.

Expert Rev Proteomics. 2011 Feb;8(1):81-94. doi: 10.1586/epr.10.104. Review.

PMID:
21329429
24.

Phosphorylation of nucleoporins: signal transduction-mediated regulation of their interaction with nuclear transport receptors.

Kosako H, Imamoto N.

Nucleus. 2010 Jul-Aug;1(4):309-13. doi: 10.4161/nucl.1.4.11744. Epub 2010 Mar 3.

25.

Phosphoproteomics reveals new ERK MAP kinase targets and links ERK to nucleoporin-mediated nuclear transport.

Kosako H, Yamaguchi N, Aranami C, Ushiyama M, Kose S, Imamoto N, Taniguchi H, Nishida E, Hattori S.

Nat Struct Mol Biol. 2009 Oct;16(10):1026-35. doi: 10.1038/nsmb.1656. Epub 2009 Sep 20.

PMID:
19767751
26.

Phosphorylation of Nephrin Triggers Ca2+ Signaling by Recruitment and Activation of Phospholipase C-{gamma}1.

Harita Y, Kurihara H, Kosako H, Tezuka T, Sekine T, Igarashi T, Ohsawa I, Ohta S, Hattori S.

J Biol Chem. 2009 Mar 27;284(13):8951-62. doi: 10.1074/jbc.M806851200. Epub 2009 Jan 29.

27.

Identification of protein kinase substrates by proteomic approaches.

Hattori S, Iida N, Kosako H.

Expert Rev Proteomics. 2008 Jun;5(3):497-505. doi: 10.1586/14789450.5.3.497. Review.

PMID:
18532915
28.

Neph1, a component of the kidney slit diaphragm, is tyrosine-phosphorylated by the Src family tyrosine kinase and modulates intracellular signaling by binding to Grb2.

Harita Y, Kurihara H, Kosako H, Tezuka T, Sekine T, Igarashi T, Hattori S.

J Biol Chem. 2008 Apr 4;283(14):9177-86. doi: 10.1074/jbc.M707247200. Epub 2008 Feb 7.

30.

Global analysis of dynamic changes in lipid raft proteins during T-cell activation.

Kobayashi M, Katagiri T, Kosako H, Iida N, Hattori S.

Electrophoresis. 2007 Jun;28(12):2035-43.

PMID:
17486660
31.

Purification of phosphoproteins by immobilized metal affinity chromatography and its application to phosphoproteome analysis.

Machida M, Kosako H, Shirakabe K, Kobayashi M, Ushiyama M, Inagawa J, Hirano J, Nakano T, Bando Y, Nishida E, Hattori S.

FEBS J. 2007 Mar;274(6):1576-87.

32.

Proteomic identification of Bcl2-associated athanogene 2 as a novel MAPK-activated protein kinase 2 substrate.

Ueda K, Kosako H, Fukui Y, Hattori S.

J Biol Chem. 2004 Oct 1;279(40):41815-21. Epub 2004 Jul 22.

33.

Transcription factor expression and Notch-dependent regulation of neural progenitors in the adult rat spinal cord.

Yamamoto S, Nagao M, Sugimori M, Kosako H, Nakatomi H, Yamamoto N, Takebayashi H, Nabeshima Y, Kitamura T, Weinmaster G, Nakamura K, Nakafuku M.

J Neurosci. 2001 Dec 15;21(24):9814-23.

34.

Combinatorial roles of olig2 and neurogenin2 in the coordinated induction of pan-neuronal and subtype-specific properties of motoneurons.

Mizuguchi R, Sugimori M, Takebayashi H, Kosako H, Nagao M, Yoshida S, Nabeshima Y, Shimamura K, Nakafuku M.

Neuron. 2001 Sep 13;31(5):757-71.

35.
36.
37.

Regulation of intermediate filament organization during cytokinesis: possible roles of Rho-associated kinase.

Goto H, Kosako H, Inagaki M.

Microsc Res Tech. 2000 Apr 15;49(2):173-82. Review.

PMID:
10816257
38.

Distribution of Rho-kinase in the bovine brain.

Hashimoto R, Nakamura Y, Kosako H, Amano M, Kaibuchi K, Inagaki M, Takeda M.

Biochem Biophys Res Commun. 1999 Sep 24;263(2):575-9.

PMID:
10491334
39.

Identification of a novel phosphorylation site on histone H3 coupled with mitotic chromosome condensation.

Goto H, Tomono Y, Ajiro K, Kosako H, Fujita M, Sakurai M, Okawa K, Iwamatsu A, Okigaki T, Takahashi T, Inagaki M.

J Biol Chem. 1999 Sep 3;274(36):25543-9.

40.

Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: cleavage furrow-specific phosphorylation of intermediate filaments.

Kosako H, Goto H, Yanagida M, Matsuzawa K, Fujita M, Tomono Y, Okigaki T, Odai H, Kaibuchi K, Inagaki M.

Oncogene. 1999 Apr 29;18(17):2783-8.

41.

Possible regulation of intermediate filament proteins by Rho-binding kinases.

Matsuzawa K, Kosako H, Azuma I, Inagaki N, Inagaki M.

Subcell Biochem. 1998;31:423-35. Review. No abstract available.

PMID:
9932501
42.

Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis.

Goto H, Kosako H, Tanabe K, Yanagida M, Sakurai M, Amano M, Kaibuchi K, Inagaki M.

J Biol Chem. 1998 May 8;273(19):11728-36.

43.

Domain-specific phosphorylation of vimentin and glial fibrillary acidic protein by PKN.

Matsuzawa K, Kosako H, Inagaki N, Shibata H, Mukai H, Ono Y, Amano M, Kaibuchi K, Matsuura Y, Azuma I, Inagaki M.

Biochem Biophys Res Commun. 1997 May 29;234(3):621-5.

PMID:
9175763
44.

Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase.

Kosako H, Amano M, Yanagida M, Tanabe K, Nishi Y, Kaibuchi K, Inagaki M.

J Biol Chem. 1997 Apr 18;272(16):10333-6.

45.

Isolation and characterization of neutralizing single-chain antibodies against Xenopus mitogen-activated protein kinase kinase from phage display libraries.

Kosako H, Akamatsu Y, Tsurushita N, Lee KK, Gotoh Y, Nishida E.

Biochemistry. 1996 Oct 8;35(40):13212-21.

PMID:
8855960
46.

Analysis of the Ras p21/mitogen-activated protein kinase signaling in vitro and in Xenopus oocytes.

Fukuda M, Gotoh Y, Kosako H, Hattori S, Nishida E.

J Biol Chem. 1994 Dec 30;269(52):33097-101.

47.

Mitogen-activated protein kinase kinase is required for the mos-induced metaphase arrest.

Kosako H, Gotoh Y, Nishida E.

J Biol Chem. 1994 Nov 11;269(45):28354-8.

48.

Characterization of recombinant Xenopus MAP kinase kinases mutated at potential phosphorylation sites.

Gotoh Y, Matsuda S, Takenaka K, Hattori S, Iwamatsu A, Ishikawa M, Kosako H, Nishida E.

Oncogene. 1994 Jul;9(7):1891-8.

PMID:
8208535
49.
50.

Regulation and function of the MAP kinase cascade in Xenopus oocytes.

Kosako H, Gotoh Y, Nishida E.

J Cell Sci Suppl. 1994;18:115-9. Review.

PMID:
7883786

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