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1.

Effect of zonisamide on parkinsonism in patients with dementia with Lewy bodies: A phase 3 randomized clinical trial.

Murata M, Odawara T, Hasegawa K, Kajiwara R, Takeuchi H, Tagawa M, Kosaka K.

Parkinsonism Relat Disord. 2019 Dec 12. pii: S1353-8020(19)30524-3. doi: 10.1016/j.parkreldis.2019.12.005. [Epub ahead of print]

2.

Prevention of venous reflux with full utilization of venoplasty in lymphaticovenular anastomosis.

Akita S, Yamaji Y, Tokumoto H, Maei H, Tezuka T, Ogata H, Kosaka K, Kubota Y, Kuriyama M, Mitsukawa N.

J Plast Reconstr Aesthet Surg. 2019 Nov 8. pii: S1748-6815(19)30488-7. doi: 10.1016/j.bjps.2019.10.020. [Epub ahead of print]

PMID:
31786137
3.

Prospective observational study on the safety of an original fiducial marker insertion for radiotherapy in gynecological cancer by a simple method.

Sekii S, Tsujino K, Kubota H, Yamaguchi S, Kosaka K, Miyazaki S, Sulaiman NS, Matsumoto Y, Ota Y, Soejima T, Sasaki R.

J Radiat Res. 2019 Nov 22;60(6):844-848. doi: 10.1093/jrr/rrz070.

4.

Heterogeneity of tyrosine hydroxylase expressing neurons in the main olfactory bulb of the mouse.

Kosaka T, Pignatelli A, Kosaka K.

Neurosci Res. 2019 Oct 17. pii: S0168-0102(19)30471-7. doi: 10.1016/j.neures.2019.10.004. [Epub ahead of print]

PMID:
31629793
5.

Adipose-Derived Stem Cells and Ceiling Culture-Derived Preadipocytes Cultured from Subcutaneous Fat Tissue Differ in Their Epigenetic Characteristics and Osteogenic Potential.

Sasahara Y, Kubota Y, Kosaka K, Adachi N, Yamaji Y, Nagano H, Akita S, Kuroda M, Tanaka T, Bujo H, Mitsukawa N.

Plast Reconstr Surg. 2019 Sep;144(3):644-655. doi: 10.1097/PRS.0000000000005913.

PMID:
31461020
6.

Adipose-Derived Stem Cells (ASCs) and Ceiling Culture-Derived Preadipocytes (ccdPAs) Cultured from Subcutaneous Fat Tissue Differ in their Epigenetic Characteristics and Osteogenic Potential.

Sasahara Y, Kubota Y, Kosaka K, Adachi N, Yamaji Y, Nagano H, Akita S, Kuroda M, Tanaka T, Bujo H, Mitsukawa N.

Plast Reconstr Surg. 2019 Jun 6. doi: 10.1097/PRS.0000000000005913. [Epub ahead of print]

PMID:
31181041
7.

Disseminated zoster in an adult patient with extensive burns: a case report.

Kubota Y, Kosaka K, Hokazono T, Yamaji Y, Tezuka T, Akita S, Kuriyama M, Mitsukawa N.

Virol J. 2019 May 23;16(1):68. doi: 10.1186/s12985-019-1179-8.

8.

Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.

Mimura J, Inose-Maruyama A, Taniuchi S, Kosaka K, Yoshida H, Yamazaki H, Kasai S, Harada N, Kaufman RJ, Oyadomari S, Itoh K.

Int J Mol Sci. 2019 Apr 5;20(7). pii: E1706. doi: 10.3390/ijms20071706.

9.

Formation of N-nitrosodimethylamine by chloramination of anthropogenic nitrogenous compounds with dimethylamine monitored by Japanese water authorities.

Hinneh KDC, El Hanafi A, He K, Kosaka K, Echigo S, Asada Y, Itoh S.

J Hazard Mater. 2019 Apr 5;367:620-628. doi: 10.1016/j.jhazmat.2018.12.102. Epub 2018 Dec 27.

PMID:
30654279
10.

High-fat diet accelerates extreme obesity with hyperphagia in female heterozygous Mecp2-null mice.

Fukuhara S, Nakajima H, Sugimoto S, Kodo K, Shigehara K, Morimoto H, Tsuma Y, Moroto M, Mori J, Kosaka K, Morimoto M, Hosoi H.

PLoS One. 2019 Jan 4;14(1):e0210184. doi: 10.1371/journal.pone.0210184. eCollection 2019.

11.

TDRKH is a candidate gene for an autosomal dominant distal hereditary motor neuropathy.

Miura S, Kosaka K, Nomura T, Nagata S, Shimojo T, Morikawa T, Fujioka R, Harada M, Taniwaki T, Shibata H.

Eur J Med Genet. 2019 Dec;62(12):103594. doi: 10.1016/j.ejmg.2018.11.028. Epub 2018 Nov 30.

PMID:
30503856
12.

Inversely designed, 3D-printed personalized template-guided interstitial brachytherapy for vaginal tumors.

Sekii S, Tsujino K, Kosaka K, Yamaguchi S, Kubota H, Matsumoto Y, Ota Y, Sasaki R, Soejima T.

J Contemp Brachytherapy. 2018 Oct;10(5):470-477. doi: 10.5114/jcb.2018.78832. Epub 2018 Oct 9.

13.

Bicytopenia in Primary Lung Melanoma Treated with Nivolumab.

Takahashi A, Kubo A, Mizuno S, Kasai K, Asai N, Yonezawa T, Kosaka K, Nishimura M, Tanaka H, Yokoe N, Tsuzuki T, Takami A, Yamaguchi E.

Intern Med. 2019 Mar 15;58(6):827-831. doi: 10.2169/internalmedicine.1011-18. Epub 2018 Nov 19.

14.

Identification of a variant associated with early-onset diabetes in the intron of the insulin gene with exome sequencing.

Matsuno S, Furuta H, Kosaka K, Doi A, Yorifuji T, Fukuda T, Senmaru T, Uraki S, Matsutani N, Furuta M, Mishima H, Iwakura H, Nishi M, Yoshiura K, Fukui M, Akamizu T.

J Diabetes Investig. 2019 Jul;10(4):947-950. doi: 10.1111/jdi.12974. Epub 2018 Dec 5.

15.

Spinocerebellar ataxia 27 with a novel nonsense variant (Lys177X) in FGF14.

Miura S, Kosaka K, Fujioka R, Uchiyama Y, Shimojo T, Morikawa T, Irie A, Taniwaki T, Shibata H.

Eur J Med Genet. 2019 Mar;62(3):172-176. doi: 10.1016/j.ejmg.2018.07.005. Epub 2018 Jul 11.

PMID:
30017992
16.

123I-MIBG myocardial scintigraphy for the diagnosis of DLB: a multicentre 3-year follow-up study.

Komatsu J, Samuraki M, Nakajima K, Arai H, Arai H, Arai T, Asada T, Fujishiro H, Hanyu H, Iizuka O, Iseki E, Kashihara K, Kosaka K, Maruno H, Mizukami K, Mizuno Y, Mori E, Nakamura H, Nakano S, Nakashima K, Nishio Y, Orimo S, Takahashi A, Taki J, Tokuda T, Urakami K, Utsumi K, Wada K, Washimi Y, Yamashina S, Yamasaki J, Yoshita M, Yamada M.

J Neurol Neurosurg Psychiatry. 2018 Nov;89(11):1167-1173. doi: 10.1136/jnnp-2017-317398. Epub 2018 May 31.

PMID:
29853532
17.

Adenovirus-mediated transfer of HPV 16 E6/E7 antisense RNA combined with cisplatin inhibits cellular growth and induces apoptosis in HPV-positive head and neck cancer cells.

Kojima Y, Otsuki N, Kubo M, Kitamoto J, Takata E, Saito H, Kosaka K, Morishita N, Uehara N, Shirakawa T, Nibu KI.

Cancer Gene Ther. 2018 Oct;25(9-10):274-283. doi: 10.1038/s41417-018-0024-3. Epub 2018 May 24.

PMID:
29795305
18.

Food polyphenols targeting peptidyl prolyl cis/trans isomerase Pin1.

Hidaka M, Kosaka K, Tsushima S, Uchida C, Takahashi K, Takahashi N, Tsubuki M, Hara Y, Uchida T.

Biochem Biophys Res Commun. 2018 May 15;499(3):681-687. doi: 10.1016/j.bbrc.2018.03.212. Epub 2018 Apr 3.

PMID:
29608894
19.

Removal of haloacetamides and their precursors at water purification plants applying ozone/biological activated carbon treatment.

Kosaka K, Iwatani A, Takeichi Y, Yoshikawa Y, Ohkubo K, Akiba M.

Chemosphere. 2018 May;198:68-74. doi: 10.1016/j.chemosphere.2018.01.093. Epub 2018 Feb 1.

PMID:
29421762
20.

Adjunct zonisamide to levodopa for DLB parkinsonism: A randomized double-blind phase 2 study.

Murata M, Odawara T, Hasegawa K, Iiyama S, Nakamura M, Tagawa M, Kosaka K.

Neurology. 2018 Feb 20;90(8):e664-e672. doi: 10.1212/WNL.0000000000005010. Epub 2018 Jan 24.

21.
22.

Arterial stiffness in junior high school students: Longitudinal observations.

Fujiwara H, Nakajima H, Inoue F, Kosaka K, Asano H, Yoshii K.

Pediatr Int. 2018 Feb;60(2):127-135. doi: 10.1111/ped.13475.

PMID:
29230906
23.

Clinical significance of serum anti-GM-CSF autoantibody levels in autoimmune pulmonary alveolar proteinosis.

Nishimura M, Yamaguchi E, Takahashi A, Asai N, Katsuda E, Ohta T, Ohtsuka Y, Kosaka K, Matsubara A, Tanaka H, Yokoe N, Kubo A, Konno S, Baba K.

Biomark Med. 2018 Feb;12(2):151-159. doi: 10.2217/bmm-2017-0362. Epub 2017 Dec 5.

PMID:
29202602
24.

Interstitial Lung Disease after Pleurodesis for Malignant Pleural Effusion.

Yokoe N, Katsuda E, Kosaka K, Hamanaka R, Matsubara A, Nishimura M, Tanaka H, Asai N, Takahashi A, Kawamura T, Ishiguchi T, Yamaguchi E, Kubo A.

Intern Med. 2017;56(14):1791-1797. doi: 10.2169/internalmedicine.56.7464. Epub 2017 Jul 15.

25.

A novel missense variant (Gln220Arg) of GNB4 encoding guanine nucleotide-binding protein, subunit beta-4 in a Japanese family with autosomal dominant motor and sensory neuropathy.

Miura S, Morikawa T, Fujioka R, Noda K, Kosaka K, Taniwaki T, Shibata H.

Eur J Med Genet. 2017 Sep;60(9):474-478. doi: 10.1016/j.ejmg.2017.06.006. Epub 2017 Jun 19.

PMID:
28642160
26.

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium.

McKeith IG, Boeve BF, Dickson DW, Halliday G, Taylor JP, Weintraub D, Aarsland D, Galvin J, Attems J, Ballard CG, Bayston A, Beach TG, Blanc F, Bohnen N, Bonanni L, Bras J, Brundin P, Burn D, Chen-Plotkin A, Duda JE, El-Agnaf O, Feldman H, Ferman TJ, Ffytche D, Fujishiro H, Galasko D, Goldman JG, Gomperts SN, Graff-Radford NR, Honig LS, Iranzo A, Kantarci K, Kaufer D, Kukull W, Lee VMY, Leverenz JB, Lewis S, Lippa C, Lunde A, Masellis M, Masliah E, McLean P, Mollenhauer B, Montine TJ, Moreno E, Mori E, Murray M, O'Brien JT, Orimo S, Postuma RB, Ramaswamy S, Ross OA, Salmon DP, Singleton A, Taylor A, Thomas A, Tiraboschi P, Toledo JB, Trojanowski JQ, Tsuang D, Walker Z, Yamada M, Kosaka K.

Neurology. 2017 Jul 4;89(1):88-100. doi: 10.1212/WNL.0000000000004058. Epub 2017 Jun 7. Review.

27.

Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice.

Kodo K, Sugimoto S, Nakajima H, Mori J, Itoh I, Fukuhara S, Shigehara K, Nishikawa T, Kosaka K, Hosoi H.

PLoS One. 2017 Mar 13;12(3):e0173661. doi: 10.1371/journal.pone.0173661. eCollection 2017.

28.

Calcium-binding protein, secretagogin, characterizes novel groups of interneurons in the rat striatum.

Kosaka T, Yasuda S, Kosaka K.

Neurosci Res. 2017 Jun;119:53-60. doi: 10.1016/j.neures.2017.01.004. Epub 2017 Feb 11.

PMID:
28193530
29.

123I-metaiodobenzylguanidine myocardial scintigraphy with early images alone is useful for the differential diagnosis of dementia with Lewy bodies.

Manabe Y, Inui Y, Toyama H, Kosaka K.

Psychiatry Res Neuroimaging. 2017 Mar 30;261:75-79. doi: 10.1016/j.pscychresns.2016.12.011. Epub 2017 Jan 20.

PMID:
28152401
30.

Asp73-dependent and -independent regulation of the affinity of ligands for human histamine H1 receptors by Na.

Hishinuma S, Kosaka K, Akatsu C, Uesawa Y, Fukui H, Shoji M.

Biochem Pharmacol. 2017 Mar 15;128:46-54. doi: 10.1016/j.bcp.2016.12.021. Epub 2016 Dec 29.

PMID:
28040476
31.

Formation of 2,6-dichloro-1,4-benzoquinone from aromatic compounds after chlorination.

Kosaka K, Nakai T, Hishida Y, Asami M, Ohkubo K, Akiba M.

Water Res. 2017 Mar 1;110:48-55. doi: 10.1016/j.watres.2016.12.005. Epub 2016 Dec 7.

PMID:
27984805
32.

Therapeutic advantage of pro-electrophilic drugs to activate the Nrf2/ARE pathway in Alzheimer's disease models.

Lipton SA, Rezaie T, Nutter A, Lopez KM, Parker J, Kosaka K, Satoh T, McKercher SR, Masliah E, Nakanishi N.

Cell Death Dis. 2016 Dec 1;7(12):e2499. doi: 10.1038/cddis.2016.389.

33.

FUT2 non-secretor status is associated with Type 1 diabetes susceptibility in Japanese children.

Ihara K, Fukano C, Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S, Sugihara S; Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT).

Diabet Med. 2017 Apr;34(4):586-589. doi: 10.1111/dme.13288. Epub 2016 Dec 15.

PMID:
27859559
34.

The ATS/ERS/JRS/ALAT statement "IPF by HRCT" could predict acute exacerbation of interstitial lung disease in non-small cell lung cancer.

Asai N, Katsuda E, Hamanaka R, Kosaka K, Matsubara A, Nishimura M, Tanaka H, Yokoe N, Takahashi A, Yamaguchi E, Kubo A.

Tumori. 2017 Jan 21;103(1):60-65. doi: 10.5301/tj.5000574. Epub 2016 Oct 22.

PMID:
27791236
35.

Response to 'Challenging the concept of diffuse neurofibrillary tangles with calcification (Kosaka-Shibayama disease)'.

Kosaka K.

Psychiatry Clin Neurosci. 2017 Jan;71(1):70-71. doi: 10.1111/pcn.12471. Epub 2016 Dec 29. No abstract available.

36.

Occurrence and formation of haloacetamides from chlorination at water purification plants across Japan.

Kosaka K, Ohkubo K, Akiba M.

Water Res. 2016 Dec 1;106:470-476. doi: 10.1016/j.watres.2016.10.029. Epub 2016 Oct 13.

PMID:
27770723
37.

Polaprezinc protects normal intestinal epithelium against exposure to ionizing radiation in mice.

Odawara S, Doi H, Shikata T, Kitajima K, Suzuki H, Niwa Y, Kosaka K, Tarutani K, Tsujimura T, Kamikonya N, Hirota S.

Mol Clin Oncol. 2016 Oct;5(4):377-381. Epub 2016 Aug 8.

38.

CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells.

Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E.

Sci Rep. 2016 Sep 23;6:34188. doi: 10.1038/srep34188.

39.

Pretreatment Cognitive Profile Likely to Benefit from Donepezil Treatment in Dementia with Lewy Bodies: Pooled Analyses of Two Randomized Controlled Trials.

Mori E, Ikeda M, Nakagawa M, Miyagishi H, Kosaka K.

Dement Geriatr Cogn Disord. 2016;42(1-2):58-68. doi: 10.1159/000447586. Epub 2016 Aug 19.

40.

Accumulated α-synuclein affects the progression of GM2 gangliosidoses.

Suzuki K, Yamaguchi A, Yamanaka S, Kanzaki S, Kawashima M, Togo T, Katsuse O, Koumitsu N, Aoki N, Iseki E, Kosaka K, Yamaguchi K, Hashimoto M, Aoki I, Hirayasu Y.

Exp Neurol. 2016 Oct;284(Pt A):38-49. doi: 10.1016/j.expneurol.2016.07.011. Epub 2016 Jul 21.

PMID:
27453479
41.

Similarity of symptoms between transient epileptic amnesia and Lewy body disease.

Ukai K, Fujishiro H, Watanabe M, Kosaka K, Ozaki N.

Psychogeriatrics. 2017 Mar;17(2):120-125. doi: 10.1111/psyg.12199. Epub 2016 Jun 30.

42.

Variants associated with autoimmune Type 1 diabetes in Japanese children: implications for age-specific effects of cis-regulatory haplotypes at 17q12-q21.

Ayabe T, Fukami M, Ogata T, Kawamura T, Urakami T, Kikuchi N, Yokota I, Ihara K, Takemoto K, Mukai T, Nishii A, Kikuchi T, Mori T, Shimura N, Sasaki G, Kizu R, Takubo N, Soneda S, Fujisawa T, Takaya R, Kizaki Z, Kanzaki S, Hanaki K, Matsuura N, Kasahara Y, Kosaka K, Takahashi T, Minamitani K, Matsuo S, Mochizuki H, Kobayashi K, Koike A, Horikawa R, Teno S, Tsubouchi K, Mochizuki T, Igarashi Y, Amemiya S, Sugihara S; Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes (JSGIT).

Diabet Med. 2016 Dec;33(12):1717-1722. doi: 10.1111/dme.13175. Epub 2016 Jul 15.

PMID:
27352912
43.

Increased plasma donepezil concentration improves cognitive function in patients with dementia with Lewy bodies: An exploratory pharmacokinetic/pharmacodynamic analysis in a phase 3 randomized controlled trial.

Mori E, Ikeda M, Nakai K, Miyagishi H, Nakagawa M, Kosaka K.

J Neurol Sci. 2016 Jul 15;366:184-190. doi: 10.1016/j.jns.2016.05.001. Epub 2016 May 4.

44.

Human adipocytes from the subcutaneous superficial layer have greater adipogenic potential and lower PPAR-γ DNA methylation levels than deep layer adipocytes.

Kosaka K, Kubota Y, Adachi N, Akita S, Sasahara Y, Kira T, Kuroda M, Mitsukawa N, Bujo H, Satoh K.

Am J Physiol Cell Physiol. 2016 Aug 1;311(2):C322-9. doi: 10.1152/ajpcell.00301.2015. Epub 2016 Jun 1.

45.

A novel frameshift mutation of DDHD1 in a Japanese patient with autosomal recessive spastic paraplegia.

Miura S, Morikawa T, Fujioka R, Kosaka K, Yamada K, Hattori G, Motomura M, Taniwaki T, Shibata H.

Eur J Med Genet. 2016 Aug;59(8):413-6. doi: 10.1016/j.ejmg.2016.05.010. Epub 2016 May 20.

PMID:
27216551
46.

Stress Characterization of 4H-SiC Metal-Oxide-Semiconductor Field-Effect Transistor (MOSFET) using Raman Spectroscopy and the Finite Element Method.

Yoshikawa M, Kosaka K, Seki H, Kimoto T.

Appl Spectrosc. 2016 Jul;70(7):1209-13. doi: 10.1177/0003702816631311. Epub 2016 May 10.

PMID:
27165155
47.

Controlling the Direction of the Molecular Axis of Rod-Shaped Binuclear Ruthenium Complexes on Single-Walled Carbon Nanotubes.

Ozawa H, Kosaka K, Kita T, Yoshikawa K, Haga MA.

Chemistry. 2016 May 4;22(19):6575-82. doi: 10.1002/chem.201504678. Epub 2016 Mar 24.

PMID:
27010865
48.

[A Case of Locally Advanced Breast Cancer Treated with Modified Radical Mastectomy with Immediate Reconstruction Using a Tissue Expander after Endocrine Therapy].

Aomatsu N, Tei S, Haraoka G, Hosoi K, Fujii N, Tsujio G, Hiramatsu S, Wang E, Iwauchi T, Morimoto J, Nishii T, Kosaka K, Uchima Y, Takeuchi K.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1812-4. Japanese.

PMID:
26805181
49.

[Effectiveness of Intraoperative Histologic Assessment of Surgical Margins for Breast-Conserving Surgery].

Aomatsu N, Tei S, Hiramatsu S, Wang E, Iwauchi T, Morimoto J, Nishii T, Kosaka K, Uchima Y, Takeuchi K.

Gan To Kagaku Ryoho. 2015 Nov;42(12):1794-6. Japanese.

PMID:
26805175
50.

Review: Miglitol has potential as a therapeutic drug against obesity.

Sugimoto S, Nakajima H, Kosaka K, Hosoi H.

Nutr Metab (Lond). 2015 Dec 1;12:51. doi: 10.1186/s12986-015-0048-8. eCollection 2015. Review.

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