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Items: 1 to 50 of 147

1.

Exploring the microbiota of upper respiratory tract during the development of pneumonia in a mouse model.

Morinaga Y, Take Y, Sasaki D, Ota K, Kaku N, Uno N, Sakamoto K, Kosai K, Miyazaki T, Hasegawa H, Izumikawa K, Mukae H, Yanagihara K.

PLoS One. 2019 Sep 27;14(9):e0222589. doi: 10.1371/journal.pone.0222589. eCollection 2019.

2.

A survivin-responsive, conditionally replicating adenovirus induces potent cytocidal effects in adult T-cell leukemia/lymphoma.

Suzuki S, Kofune H, Uozumi K, Yoshimitsu M, Arima N, Ishitsuka K, Ueno SI, Kosai KI.

BMC Cancer. 2019 May 29;19(1):516. doi: 10.1186/s12885-019-5730-1.

3.

Efficacy and safety of cefditoren pivoxil for exacerbations of chronic obstructive pulmonary disease: A prospective multicenter interventional study.

Miyazaki T, Fukushima K, Hashiguchi K, Inoue Y, Mihara T, Sawai T, Suyama N, Kobayashi T, Kondo A, Fukuda Y, Harada Y, Sasaki E, Kaku N, Ide S, Takazono T, Saijo T, Kosai K, Morinaga Y, Nakamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H.

J Infect Chemother. 2019 Sep;25(9):702-707. doi: 10.1016/j.jiac.2019.03.018. Epub 2019 Apr 11.

4.

Detection of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae using the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay.

Kawamoto Y, Kosai K, Yamakawa H, Kaku N, Uno N, Morinaga Y, Hasegawa H, Yanagihara K.

J Microbiol Methods. 2019 May;160:154-156. doi: 10.1016/j.mimet.2019.03.019. Epub 2019 Mar 20.

PMID:
30904555
5.

Molecular epidemiology of Clostridioides difficile and risk factors for the detection of toxin gene-positive strains.

Okada Y, Kaku N, Kosai K, Uno N, Morinaga Y, Hasegawa H, Yanagihara K.

J Infect Chemother. 2019 Apr;25(4):262-266. doi: 10.1016/j.jiac.2018.12.004. Epub 2019 Jan 12.

PMID:
30642771
6.

Molecular and epidemiological analysis of IMP-1 metallo-β-lactamase-producing Klebsiella pneumoniae in a tertiary care hospital in Japan.

Yamakawa H, Kosai K, Akamatsu N, Matsuda J, Kaku N, Uno N, Morinaga Y, Hasegawa H, Tsubouchi T, Kaneko Y, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

J Infect Chemother. 2019 Apr;25(4):240-246. doi: 10.1016/j.jiac.2018.11.012. Epub 2019 Jan 2.

PMID:
30611637
7.

Risk Factors for Acquisition of Fluoroquinolone or Aminoglycoside Resistance in Addition to Carbapenem Resistance in Pseudomonas aeruginosa.

Kosai K, Kaku N, Uno N, Saijo T, Morinaga Y, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Open Microbiol J. 2018 Sep 28;12:321-322. doi: 10.2174/1874285801812010321. eCollection 2018. No abstract available.

8.

Primary Oral Mucormycosis Due to Rhizopus microsporus after Allogeneic Stem Cell Transplantation.

Sakamoto H, Itonaga H, Sawayama Y, Taguchi J, Saijo T, Kuwatsuka S, Hashisako M, Kinoshita N, Oishi M, Doi H, Kosai K, Nishimoto K, Tanaka K, Yanagihara K, Mukae H, Izumikawa K, Miyazaki Y.

Intern Med. 2018;57(17):2567-2571. doi: 10.2169/internalmedicine.0474-17. Epub 2018 Sep 1.

9.

Performance evaluation of the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay for the detection of IMP metallo-β-lactamase activity in Enterobacteriaceae.

Kawamoto Y, Kosai K, Yamakawa H, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Diagn Microbiol Infect Dis. 2018 Dec;92(4):275-278. doi: 10.1016/j.diagmicrobio.2018.06.018. Epub 2018 Jun 27.

PMID:
30041842
10.

Evaluation of FilmArray respiratory panel multiplex polymerase chain reaction assay for detection of pathogens in adult outpatients with acute respiratory tract infection.

Kaku N, Hashiguchi K, Iwanaga Y, Akamatsu N, Matsuda J, Kosai K, Uno N, Morinaga Y, Kitazaki T, Hasegawa H, Miyazaki T, Fukuda M, Izumikawa K, Mukae H, Yanagihara K.

J Infect Chemother. 2018 Sep;24(9):734-738. doi: 10.1016/j.jiac.2018.05.006. Epub 2018 Jun 9.

PMID:
29895452
11.

Plasmid-Mediated AmpC β-Lactamase and Underestimation of Extended-Spectrum β-Lactamase in Cefepime-Susceptible Elevated-Ceftazidime-MIC Enterobacteriaceae Isolates.

Nishimura F, Morinaga Y, Akamatsu N, Matsuda J, Kaku N, Takeda K, Uno N, Kosai K, Hasegawa H, Yanagihara K.

Jpn J Infect Dis. 2018 Jul 24;71(4):281-285. doi: 10.7883/yoken.JJID.2017.469. Epub 2018 Apr 27.

12.

In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions.

Murata M, Kosai K, Yamauchi S, Sasaki D, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Antimicrob Agents Chemother. 2018 Mar 27;62(4). pii: e01971-17. doi: 10.1128/AAC.01971-17. Print 2018 Apr.

13.

M1 and M2 Monocytes in Rheumatoid Arthritis: A Contribution of Imbalance of M1/M2 Monocytes to Osteoclastogenesis.

Fukui S, Iwamoto N, Takatani A, Igawa T, Shimizu T, Umeda M, Nishino A, Horai Y, Hirai Y, Koga T, Kawashiri SY, Tamai M, Ichinose K, Nakamura H, Origuchi T, Masuyama R, Kosai K, Yanagihara K, Kawakami A.

Front Immunol. 2018 Jan 8;8:1958. doi: 10.3389/fimmu.2017.01958. eCollection 2017.

14.

Susceptibility of Clostridium species isolated in Japan to fidaxomicin and its major metabolite OP-1118.

Yanagihara K, Akamatsu N, Matsuda J, Kaku N, Katsumata K, Kosai K.

J Infect Chemother. 2018 Jun;24(6):492-495. doi: 10.1016/j.jiac.2017.12.006. Epub 2018 Jan 17.

15.

Performance evaluation of BD Phoenix™, an automated microbiology system, for the screening of IMP-producing Enterobacteriaceae.

Yamakawa H, Kosai K, Kawamoto Y, Akamatsu N, Matsuda J, Kaku N, Uno N, Morinaga Y, Hasegawa H, Yanagihara K.

J Microbiol Methods. 2018 Feb;145:47-49. doi: 10.1016/j.mimet.2017.12.006. Epub 2017 Dec 16.

PMID:
29258740
16.

A Novel Construction of Lentiviral Vectors for Eliminating Tumorigenic Cells from Pluripotent Stem Cells.

Ide K, Mitsui K, Irie R, Matsushita Y, Ijichi N, Toyodome S, Kosai KI.

Stem Cells. 2018 Feb;36(2):230-239. doi: 10.1002/stem.2725. Epub 2017 Nov 8.

17.

Pathogenesis of Lethal Aspiration Pneumonia in Mecp2-null Mouse Model for Rett Syndrome.

Kida H, Takahashi T, Nakamura Y, Kinoshita T, Hara M, Okamoto M, Okayama S, Nakamura K, Kosai KI, Taniwaki T, Yamashita Y, Matsuishi T.

Sci Rep. 2017 Sep 20;7(1):12032. doi: 10.1038/s41598-017-12293-8.

18.

Fluoroquinolone resistance in extended-spectrum β-lactamase-producing Klebsiella pneumoniae in a Japanese tertiary hospital: silent shifting to CTX-M-15-producing K. pneumoniae.

Higashino M, Murata M, Morinaga Y, Akamatsu N, Matsuda J, Takeda K, Kaku N, Kosai K, Uno N, Hasegawa H, Yanagihara K.

J Med Microbiol. 2017 Oct;66(10):1476-1482. doi: 10.1099/jmm.0.000577. Epub 2017 Sep 12.

PMID:
28893357
19.

Strong influence of human leukocyte antigen-DP variants on response to hepatitis B vaccine in a Japanese population.

Okada Y, Uno N, Sato S, Mori S, Sasaki D, Kaku N, Kosai K, Morinaga Y, Hasegawa H, Yanagihara K.

Vaccine. 2017 Oct 9;35(42):5662-5665. doi: 10.1016/j.vaccine.2017.08.045. Epub 2017 Sep 4.

PMID:
28882445
20.

Performance evaluation of the Verigene®Clostridium difficile nucleic acid test, an automated multiplex molecular testing system for detection of C. difficile toxin.

Kosai K, Iwanaga Y, Akamatsu N, Okada Y, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

J Infect Chemother. 2017 Oct;23(10):674-677. doi: 10.1016/j.jiac.2017.07.002. Epub 2017 Jul 24.

PMID:
28751156
21.

Tedizolid inhibits MUC5AC production induced by methicillin-resistant Staphylococcus aureus in human airway epithelial cells.

Takeda K, Kaku N, Morinaga Y, Kosai K, Uno N, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

J Infect Chemother. 2017 Sep;23(9):598-603. doi: 10.1016/j.jiac.2017.04.015. Epub 2017 Jul 17.

PMID:
28729052
22.

Risk Factors for Acquisition of Fluoroquinolone or Aminoglycoside Resistance in Addition to Carbapenem Resistance in Pseudomonas Aeruginosa.

Kosai K, Kaku N, Uno N, Saijo T, Morinaga Y, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Open Microbiol J. 2017 May 31;11:92-97. doi: 10.2174/1874285801711010092. eCollection 2017.

23.

Efficacy and Pharmacokinetics of the Combination of OP0595 and Cefepime in a Mouse Model of Pneumonia Caused by Extended-Spectrum-Beta-Lactamase-Producing Klebsiella pneumoniae.

Kaku N, Kosai K, Takeda K, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Antimicrob Agents Chemother. 2017 Jun 27;61(7). pii: e00828-17. doi: 10.1128/AAC.00828-17. Print 2017 Jul.

24.

Viral Vector-Based Innovative Approaches to Directly Abolishing Tumorigenic Pluripotent Stem Cells for Safer Regenerative Medicine.

Mitsui K, Ide K, Takahashi T, Kosai KI.

Mol Ther Methods Clin Dev. 2017 Mar 18;5:51-58. doi: 10.1016/j.omtm.2017.03.002. eCollection 2017 Jun 16. Review.

25.

Efficacy and pharmacokinetics of ME1100, a novel optimized formulation of arbekacin for inhalation, compared with amikacin in a murine model of ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

Kaku N, Morinaga Y, Takeda K, Kosai K, Uno N, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

J Antimicrob Chemother. 2017 Apr 1;72(4):1123-1128. doi: 10.1093/jac/dkw517.

PMID:
27999047
26.

TNF-α inhibits the growth of Legionella pneumophila in airway epithelial cells by inducing apoptosis.

Kawamoto Y, Morinaga Y, Kimura Y, Kaku N, Kosai K, Uno N, Hasegawa H, Yanagihara K.

J Infect Chemother. 2017 Jan;23(1):51-55. doi: 10.1016/j.jiac.2016.09.010. Epub 2016 Nov 17.

PMID:
27865699
27.

Heparin-binding epidermal growth factor-like growth factor and hepatocyte growth factor inhibit cholestatic liver injury in mice through different mechanisms.

Sakamoto K, Khai NC, Wang Y, Irie R, Takamatsu H, Matsufuji H, Kosai KI.

Int J Mol Med. 2016 Dec;38(6):1673-1682. doi: 10.3892/ijmm.2016.2784. Epub 2016 Oct 20.

28.

Simultaneous screening for JAK2 and calreticulin gene mutations in myeloproliferative neoplasms with high resolution melting.

Matsumoto N, Mori S, Hasegawa H, Sasaki D, Mori H, Tsuruda K, Imanishi D, Imaizumi Y, Hata T, Kaku N, Kosai K, Uno N, Miyazaki Y, Yanagihara K.

Clin Chim Acta. 2016 Nov 1;462:166-173. doi: 10.1016/j.cca.2016.09.023. Epub 2016 Sep 29.

29.

[Ebola Virus Disease (Ebola Hemorrhagic Fever)].

Yanagihara K, Sasaki D, Akamatsu N, Kaku N, Kosai K.

Rinsho Byori. 2016 Sep;64(9):1025-1032. Review. Japanese.

PMID:
30609455
30.

Premedication with Clarithromycin Is Effective against Secondary Bacterial Pneumonia during Influenza Virus Infection in a Pulmonary Emphysema Mouse Model.

Harada T, Ishimatsu Y, Hara A, Morita T, Nakashima S, Kakugawa T, Sakamoto N, Kosai K, Izumikawa K, Yanagihara K, Mukae H, Kohno S.

J Pharmacol Exp Ther. 2016 Sep;358(3):457-63. doi: 10.1124/jpet.116.233932. Epub 2016 Jul 11.

PMID:
27489022
31.

[Diagnostic Utilities of an Automated and Standardized DNA Quantification during Cytomegalovirus Monitoring].

Mori S, Morinaga Y, Nishimura F, Murata M, Umihata S, Sasaki D, Kaku N, Kosai K, Uno N, Taguchi J, Hasegawa H, Miyazaki Y, Yanagihara K.

Rinsho Byori. 2016 Aug;64(8):881-886. Japanese.

PMID:
30609324
32.

Efficient elimination of pancreatic cancer stem cells by hedgehog/GLI inhibitor GANT61 in combination with mTOR inhibition.

Miyazaki Y, Matsubara S, Ding Q, Tsukasa K, Yoshimitsu M, Kosai K, Takao S.

Mol Cancer. 2016 Jun 27;15(1):49. doi: 10.1186/s12943-016-0534-2.

33.

Clinical application of a ligation-independent pathway of multiplex ligation-dependent probe amplification for the determination of quinolone susceptibility of Streptococcus pneumoniae.

Uno N, Araki N, Kaku N, Kosai K, Hasegawa H, Yanagihara K.

J Microbiol Methods. 2016 Sep;128:13-15. doi: 10.1016/j.mimet.2016.06.024. Epub 2016 Jun 23.

PMID:
27343683
34.

The effect of tooth brushing, irrigation, and topical tetracycline administration on the reduction of oral bacteria in mechanically ventilated patients: a preliminary study.

Hayashida S, Funahara M, Sekino M, Yamaguchi N, Kosai K, Yanamoto S, Yanagihara K, Umeda M.

BMC Oral Health. 2016 Jun 7;16(1):67. doi: 10.1186/s12903-016-0224-x.

35.

Antimicrobial and immunomodulatory effects of tedizolid against methicillin-resistant Staphylococcus aureus in a murine model of hematogenous pulmonary infection.

Kaku N, Morinaga Y, Takeda K, Kosai K, Uno N, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K.

Int J Med Microbiol. 2016 Sep;306(6):421-8. doi: 10.1016/j.ijmm.2016.05.010. Epub 2016 May 19.

PMID:
27259840
36.

Induction of apoptosis by HBI-8000 in adult T-cell leukemia/lymphoma is associated with activation of Bim and NLRP3.

Hasegawa H, Bissonnette RP, Gillings M, Sasaki D, Taniguchi H, Kitanosono H, Tsuruda K, Kosai K, Uno N, Morinaga Y, Imaizumi Y, Miyazaki Y, Yanagihara K.

Cancer Sci. 2016 Aug;107(8):1124-33. doi: 10.1111/cas.12971. Epub 2016 Jun 22.

37.

Pulmonary Nocardiosis Caused by Nocardia concava with a Literature Review.

Hirayama T, Takazono T, Horai Y, Tashiro M, Saijo T, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Izumikawa K, Yanagihara K, Kawakami A, Kohno S.

Intern Med. 2016;55(9):1213-7. doi: 10.2169/internalmedicine.55.6228. Epub 2016 May 1.

38.

The Rapid Induction of Carbapenem-Resistance in an Aeromonas dhakensis Blood Isolate.

Murata M, Morinaga Y, Akamatsu N, Matsuda J, Uno N, Kosai K, Hasegawa H, Okada M, Moriuchi H, Yanagihara K.

Jpn J Infect Dis. 2016 Sep 21;69(5):439-41. doi: 10.7883/yoken.JJID.2015.098. Epub 2016 Jan 8.

39.

Intravenous Administration of Endothelial Colony-Forming Cells Overexpressing Integrin β1 Augments Angiogenesis in Ischemic Legs.

Goto K, Takemura G, Takahashi T, Okada H, Kanamori H, Kawamura I, Watanabe T, Morishita K, Tsujimoto A, Miyazaki N, Ushikoshi H, Kawasaki M, Mikami A, Kosai K, Minatoguchi S.

Stem Cells Transl Med. 2016 Feb;5(2):218-26. doi: 10.5966/sctm.2015-0096. Epub 2015 Dec 23.

40.

Antimicrobial susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus in a Japanese secondary care facility.

Kimura Y, Morinaga Y, Akamatsu N, Matsuda J, Yamaryo T, Kawakami K, Matsuo H, Kosai K, Uno N, Hasegawa H, Yanagihara K.

J Infect Chemother. 2016 Jan;22(1):14-8. doi: 10.1016/j.jiac.2015.08.011. Epub 2015 Nov 24.

PMID:
26617349
41.

The risk factors for developing of chronic pulmonary aspergillosis in nontuberculous mycobacteria patients and clinical characteristics and outcomes in chronic pulmonary aspergillosis patients coinfected with nontuberculous mycobacteria.

Takeda K, Imamura Y, Takazono T, Yoshida M, Ide S, Hirano K, Tashiro M, Saijo T, Kosai K, Morinaga Y, Nakamura S, Kurihara S, Tsukamoto M, Miyazaki T, Tashiro T, Kohno S, Yanagihara K, Izumikawa K.

Med Mycol. 2016 Feb;54(2):120-7. doi: 10.1093/mmy/myv093. Epub 2015 Nov 3.

PMID:
26531100
42.

Conditionally replicating adenovirus prevents pluripotent stem cell-derived teratoma by specifically eliminating undifferentiated cells.

Mitsui K, Ide K, Takayama A, Wada T, Irie R, Kosai K.

Mol Ther Methods Clin Dev. 2015 Aug 12;2:15026. doi: 10.1038/mtm.2015.26. eCollection 2015.

43.

Efficacy of topical antibiotic administration on the inhibition of perioperative oral bacterial growth in oral cancer patients: a preliminary study.

Funahara M, Hayashida S, Sakamoto Y, Yanamoto S, Kosai K, Yanagihara K, Umeda M.

Int J Oral Maxillofac Surg. 2015 Oct;44(10):1225-30. doi: 10.1016/j.ijom.2015.06.002. Epub 2015 Jun 26.

PMID:
26119366
44.

Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias.

Hara M, Takahashi T, Mitsumasu C, Igata S, Takano M, Minami T, Yasukawa H, Okayama S, Nakamura K, Okabe Y, Tanaka E, Takemura G, Kosai K, Yamashita Y, Matsuishi T.

Sci Rep. 2015 Jun 15;5:11204. doi: 10.1038/srep11204.

45.

Three cases of concurrent infection with Mycobacterium tuberculosis and Cryptococcus neoformans.

Kakeya H, Izumikawa K, Yamada K, Obata Y, Nishino T, Takazono T, Kosai K, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Tashiro T, Kohno S.

Intern Med. 2014;53(15):1685-92. Epub 2014 Aug 1.

46.

Importance of functional assessment in the management of community-acquired and healthcare-associated pneumonia.

Kosai K, Izumikawa K, Imamura Y, Tanaka H, Tsukamoto M, Kurihara S, Takazono T, Morinaga Y, Nakamura S, Miyazaki T, Yanagihara K, Tashiro T, Kohno S.

Intern Med. 2014;53(15):1613-20. Epub 2014 Aug 1.

47.

Concurrent subcutaneous candidal abscesses and pulmonary cryptococcosis in a patient with diabetes mellitus and a history of corticosteroid therapy.

Kakeya H, Izumikawa K, Yamada K, Narita Y, Nishino T, Obata Y, Takazono T, Kurihara S, Kosai K, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Takenaka M, Tashiro T, Kohno S.

Intern Med. 2014;53(12):1385-90. Epub 2014 Jun 15.

48.

Efficacy of combination therapy with oseltamivir phosphate and azithromycin for influenza: a multicenter, open-label, randomized study.

Kakeya H, Seki M, Izumikawa K, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Tashiro T, Kohno S.

PLoS One. 2014 Mar 14;9(3):e91293. doi: 10.1371/journal.pone.0091293. eCollection 2014.

49.

Intramuscular injection of adenoviral hepatocyte growth factor at a distal site ameliorates dextran sodium sulfate-induced colitis in mice.

Yuge K, Takahashi T, Khai NC, Goto K, Fujiwara T, Fujiwara H, Kosai K.

Int J Mol Med. 2014 May;33(5):1064-74. doi: 10.3892/ijmm.2014.1686. Epub 2014 Mar 6.

50.

Pathogenesis and clinical features of chronic pulmonary aspergillosis - is it possible to distinguish CNPA and CCPA clinically?

Izumikawa K, Tashiro T, Tashiro M, Takazono T, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Kakeya H, Hayashi T, Yanagihara K, Nagayasu T, Kohno S.

J Infect Chemother. 2014 Mar;20(3):208-12. doi: 10.1016/j.jiac.2013.10.016. Epub 2013 Dec 11.

PMID:
24477329

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