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Items: 1 to 50 of 125

1.

Prediction of tissue - plasma partition coefficients using microsomal partitioning: Incorporation into physiologically-based pharmacokinetic models and steady state volume of distribution predictions.

Holt K, Ye M, Nagar S, Korzekwa KR.

Drug Metab Dispos. 2019 Jul 19. pii: dmd.119.087973. doi: 10.1124/dmd.119.087973. [Epub ahead of print]

2.

Impact of Lipid Partitioning on the Design, Analysis, and Interpretation of Microsomal Time-Dependent Inactivation.

Yadav J, Korzekwa K, Nagar S.

Drug Metab Dispos. 2019 Jul;47(7):732-742. doi: 10.1124/dmd.118.085969. Epub 2019 May 1.

PMID:
31043439
3.

Avoiding Irreversibility: Engineering Resonant Conversions of Quantum Resources.

Korzekwa K, Chubb CT, Tomamichel M.

Phys Rev Lett. 2019 Mar 22;122(11):110403. doi: 10.1103/PhysRevLett.122.110403.

PMID:
30951333
4.

Antimicrobial Resistance and Biofilm Formation in Enterococcus spp. Isolated from Humans and Turkeys in Poland.

Woźniak-Biel A, Bugla-Płoskońska G, Burdzy J, Korzekwa K, Ploch S, Wieliczko A.

Microb Drug Resist. 2019 Mar;25(2):277-286. doi: 10.1089/mdr.2018.0221. Epub 2019 Jan 30.

5.

Complex Signaling Networks Controlling Dynamic Molecular Changes in Pseudomonas aeruginosa Biofilm.

Guła G, Dorotkiewicz-Jach A, Korzekwa K, Valvano MA, Drulis-Kawa Z.

Curr Med Chem. 2019;26(11):1979-1993. doi: 10.2174/0929867325666180912110151. Review.

PMID:
30207213
6.

Identification of Yersinia enterocolitica isolates from humans, pigs and wild boars by MALDI TOF MS.

Morka K, Bystroń J, Bania J, Korzeniowska-Kowal A, Korzekwa K, Guz-Regner K, Bugla-Płoskońska G.

BMC Microbiol. 2018 Aug 17;18(1):86. doi: 10.1186/s12866-018-1228-2.

7.

Molecular Modeling of Drug-Transporter Interactions-An International Transporter Consortium Perspective.

Schlessinger A, Welch MA, van Vlijmen H, Korzekwa K, Swaan PW, Matsson P.

Clin Pharmacol Ther. 2018 Nov;104(5):818-835. doi: 10.1002/cpt.1174. Epub 2018 Aug 30.

PMID:
29981151
8.

Improved Predictions of Drug-Drug Interactions Mediated by Time-Dependent Inhibition of CYP3A.

Yadav J, Korzekwa K, Nagar S.

Mol Pharm. 2018 May 7;15(5):1979-1995. doi: 10.1021/acs.molpharmaceut.8b00129. Epub 2018 Apr 10.

9.

Anti-enterococcal activities of pentacyclic triterpenes.

Wojnicz D, Tichaczek-Goska D, Korzekwa K, Kicia M, Hendrich A.

Adv Clin Exp Med. 2017 May-Jun;26(3):483-490. doi: 10.17219/acem/62245.

10.

Continuous Intestinal Absorption Model Based on the Convection-Diffusion Equation.

Nagar S, Korzekwa RC, Korzekwa K.

Mol Pharm. 2017 Sep 5;14(9):3069-3086. doi: 10.1021/acs.molpharmaceut.7b00286. Epub 2017 Jul 31.

11.

Relationship of Triamine-Biocide Tolerance of Salmonella enterica Serovar Senftenberg to Antimicrobial Susceptibility, Serum Resistance and Outer Membrane Proteins.

Futoma-Kołoch B, Dudek B, Kapczyńska K, Krzyżewska E, Wańczyk M, Korzekwa K, Rybka J, Klausa E, Bugla-Płoskońska G.

Int J Mol Sci. 2017 Jul 11;18(7). pii: E1459. doi: 10.3390/ijms18071459.

12.

Numerical analysis of time dependent inhibition kinetics: comparison between rat liver microsomes and rat hepatocyte data for mechanistic model fitting.

Pham C, Nagar S, Korzekwa K.

Xenobiotica. 2017 Jun 23:1-28. doi: 10.1080/00498254.2017.1345020. [Epub ahead of print]

13.

High Prevalence of Resistance to Fluoroquinolones and Tetracycline Campylobacter Spp. Isolated from Poultry in Poland.

Woźniak-Biel A, Bugla-Płoskońska G, Kielsznia A, Korzekwa K, Tobiasz A, Korzeniowska-Kowal A, Wieliczko A.

Microb Drug Resist. 2018 Apr;24(3):314-322. doi: 10.1089/mdr.2016.0249. Epub 2017 Jun 19.

14.

On the Nature of Physiologically-Based Pharmacokinetic Models -A Priori or A Posteriori? Mechanistic or Empirical?

Korzekwa K, Nagar S.

Pharm Res. 2017 Mar;34(3):529-534. doi: 10.1007/s11095-016-2089-8. Epub 2016 Dec 27. Review.

15.

Drug Distribution. Part 1. Models to Predict Membrane Partitioning.

Nagar S, Korzekwa K.

Pharm Res. 2017 Mar;34(3):535-543. doi: 10.1007/s11095-016-2085-z. Epub 2016 Dec 15.

16.

Drug Distribution Part 2. Predicting Volume of Distribution from Plasma Protein Binding and Membrane Partitioning.

Korzekwa K, Nagar S.

Pharm Res. 2017 Mar;34(3):544-551. doi: 10.1007/s11095-016-2086-y. Epub 2016 Dec 13.

17.

Proteomic Analysis of Outer Membrane Proteins from Salmonella Enteritidis Strains with Different Sensitivity to Human Serum.

Dudek B, Krzyżewska E, Kapczyńska K, Rybka J, Pawlak A, Korzekwa K, Klausa E, Bugla-Płoskońska G.

PLoS One. 2016 Oct 3;11(10):e0164069. doi: 10.1371/journal.pone.0164069. eCollection 2016.

18.

Study of the impact of cranberry extract on the virulence factors and biofilm formation by Enterococcus faecalis strains isolated from urinary tract infections.

Wojnicz D, Tichaczek-Goska D, Korzekwa K, Kicia M, Hendrich AB.

Int J Food Sci Nutr. 2016 Dec;67(8):1005-16. doi: 10.1080/09637486.2016.1211996. Epub 2016 Jul 26.

PMID:
27456160
19.

Intracellular Unbound Atorvastatin Concentrations in the Presence of Metabolism and Transport.

Kulkarni P, Korzekwa K, Nagar S.

J Pharmacol Exp Ther. 2016 Oct;359(1):26-36. doi: 10.1124/jpet.116.235689. Epub 2016 Jul 22. Erratum in: J Pharmacol Exp Ther. 2017 Apr;361(1):198.

20.

Development and evaluation of viscosity-enhanced nanocarrier (VEN) for oral insulin delivery.

Boushra M, Tous S, Fetih G, Korzekwa K, Lebo DB, Xue HY, Wong HL.

Int J Pharm. 2016 Sep 10;511(1):462-472. doi: 10.1016/j.ijpharm.2016.07.016. Epub 2016 Jul 11.

PMID:
27418563
21.

Mechanism-Based Inhibition of CYP3A4 by Podophyllotoxin: Aging of an Intermediate Is Important for in Vitro/in Vivo Correlations.

Barnaba C, Yadav J, Nagar S, Korzekwa K, Jones JP.

Mol Pharm. 2016 Aug 1;13(8):2833-43. doi: 10.1021/acs.molpharmaceut.6b00436. Epub 2016 Jul 1.

22.

The case of #arseniclife: Blogs and Twitter in informal peer review.

Yeo SK, Liang X, Brossard D, Rose KM, Korzekwa K, Scheufele DA, Xenos MA.

Public Underst Sci. 2017 Nov;26(8):937-952. doi: 10.1177/0963662516649806. Epub 2016 May 26.

PMID:
27229853
23.

Silver Nanoforms as a Therapeutic Agent for Killing Escherichia coli and Certain ESKAPE Pathogens.

Kedziora A, Korzekwa K, Strek W, Pawlak A, Doroszkiewicz W, Bugla-Ploskonska G.

Curr Microbiol. 2016 Jul;73(1):139-47. doi: 10.1007/s00284-016-1034-8. Epub 2016 Apr 16.

24.

Selection and electrophoretic characterization of Salmonella enterica subsp. enterica biocide variants resistant to antibiotics.

Futoma-Kołoch B, Książczyk M, Korzekwa K, Migdał I, Pawlak A, Jankowska M, Kędziora A, Dorotkiewicz-Jach A, Bugla-Płoskońska G.

Pol J Vet Sci. 2015;18(4):725-32. doi: 10.1515/pjvs-2015-0094.

PMID:
26812813
25.

Application of Routine Diagnostic Procedure, VITEK 2 Compact, MALDI-TOF MS, and PCR Assays in Identification Procedure of Bacterial Strain with Ambiguous Phenotype.

Książczyk M, Kuczkowski M, Dudek B, Korzekwa K, Tobiasz A, Korzeniowska-Kowal A, Paluch E, Wieliczko A, Bugla-Płoskońska G.

Curr Microbiol. 2016 May;72(5):570-82. doi: 10.1007/s00284-016-0993-0. Epub 2016 Jan 25.

PMID:
26804795
26.
27.

Heterocyclic chalcone activators of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) with improved in vivo efficacy.

Lounsbury N, Mateo G, Jones B, Papaiahgari S, Thimmulappa RK, Teijaro C, Gordon J, Korzekwa K, Ye M, Allaway G, Abou-Gharbia M, Biswal S, Childers W Jr.

Bioorg Med Chem. 2015 Sep 1;23(17):5352-9. doi: 10.1016/j.bmc.2015.07.056. Epub 2015 Jul 29.

PMID:
26278028
28.

A numerical method for analysis of in vitro time-dependent inhibition data. Part 1. Theoretical considerations.

Nagar S, Jones JP, Korzekwa K.

Drug Metab Dispos. 2014 Sep;42(9):1575-86. doi: 10.1124/dmd.114.058289. Epub 2014 Jun 17.

29.

A numerical method for analysis of in vitro time-dependent inhibition data. Part 2. Application to experimental data.

Korzekwa K, Tweedie D, Argikar UA, Whitcher-Johnstone A, Bell L, Bickford S, Nagar S.

Drug Metab Dispos. 2014 Sep;42(9):1587-95. doi: 10.1124/dmd.114.058297. Epub 2014 Jun 17.

30.

Case study 4. Predicting the drug interaction potential for inhibition of CYP2C8 by montelukast.

Korzekwa K.

Methods Mol Biol. 2014;1113:461-9. doi: 10.1007/978-1-62703-758-7_21.

PMID:
24523125
31.

Enzyme kinetics of oxidative metabolism: cytochromes P450.

Korzekwa K.

Methods Mol Biol. 2014;1113:149-66. doi: 10.1007/978-1-62703-758-7_8. Review.

PMID:
24523112
32.

PKCθ regulates T cell motility via ezrin-radixin-moesin localization to the uropod.

Cannon JL, Asperti-Boursin F, Letendre KA, Brown IK, Korzekwa KE, Blaine KM, Oruganti SR, Sperling AI, Moses ME.

PLoS One. 2013 Nov 8;8(11):e78940. doi: 10.1371/journal.pone.0078940. eCollection 2013.

33.

Compartmental models for apical efflux by P-glycoprotein--part 1: evaluation of model complexity.

Nagar S, Tucker J, Weiskircher EA, Bhoopathy S, Hidalgo IJ, Korzekwa K.

Pharm Res. 2014 Feb;31(2):347-59. doi: 10.1007/s11095-013-1164-7. Epub 2013 Sep 10.

34.

Influence of microflora composition on safety and colour parameters of "kumpia wieprzowa" during ripening.

Wesierska E, Korzekwa K, Foks S, Mickowska B.

Pol J Vet Sci. 2013;16(2):299-305.

PMID:
23971198
36.

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.

Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium.

Clin Pharmacol Ther. 2013 Jul;94(1):126-41. doi: 10.1038/clpt.2013.78. Epub 2013 Apr 10. Review.

37.

ITC recommendations for transporter kinetic parameter estimation and translational modeling of transport-mediated PK and DDIs in humans.

Zamek-Gliszczynski MJ, Lee CA, Poirier A, Bentz J, Chu X, Ellens H, Ishikawa T, Jamei M, Kalvass JC, Nagar S, Pang KS, Korzekwa K, Swaan PW, Taub ME, Zhao P, Galetin A; International Transporter Consortium.

Clin Pharmacol Ther. 2013 Jul;94(1):64-79. doi: 10.1038/clpt.2013.45. Epub 2013 Feb 25. Review.

38.

Predicting intrinsic clearance for drugs and drug candidates metabolized by aldehyde oxidase.

Jones JP, Korzekwa KR.

Mol Pharm. 2013 Apr 1;10(4):1262-8. doi: 10.1021/mp300568r. Epub 2013 Feb 13.

39.

Commentary: nonspecific protein binding versus membrane partitioning: it is not just semantics.

Nagar S, Korzekwa K.

Drug Metab Dispos. 2012 Sep;40(9):1649-52. doi: 10.1124/dmd.112.046599. Epub 2012 Jun 18.

PMID:
22711748
40.

Models to predict unbound intracellular drug concentrations in the presence of transporters.

Korzekwa KR, Nagar S, Tucker J, Weiskircher EA, Bhoopathy S, Hidalgo IJ.

Drug Metab Dispos. 2012 May;40(5):865-76. doi: 10.1124/dmd.111.044289. Epub 2012 Jan 25.

PMID:
22279052
41.

Characterization of borderline oxacillin-resistant Staphylococcus aureus isolated from food of animal origin.

Bystroń J, Podkowik M, Korzekwa K, Lis E, Molenda J, Bania J.

J Food Prot. 2010 Jul;73(7):1325-7.

PMID:
20615346
42.

Enterotoxin gene content in Staphylococcus aureus from the human intestinal tract.

Lis E, Korzekwa K, Bystroń J, Zarczyńska A, Dabrowska A, Molenda J, Bania J.

FEMS Microbiol Lett. 2009 Jul;296(1):72-7. doi: 10.1111/j.1574-6968.2009.01622.x. Epub 2009 May 5.

43.
44.

Impact of pH on plasma protein binding in equilibrium dialysis.

Kochansky CJ, McMasters DR, Lu P, Koeplinger KA, Kerr HH, Shou M, Korzekwa KR.

Mol Pharm. 2008 May-Jun;5(3):438-48. doi: 10.1021/mp800004s. Epub 2008 Mar 18.

PMID:
18345638
45.

[Bactericidal action of human serum against Pseudomonas aeruginosa strains with hydrophilic or hydrophobic cell surface].

Wojnicz D, Korzekwa K, Cisowska A.

Med Dosw Mikrobiol. 2008;60(4):303-9. Polish.

PMID:
19382602
46.

Use of density functional calculations to predict the regioselectivity of drugs and molecules metabolized by aldehyde oxidase.

Torres RA, Korzekwa KR, McMasters DR, Fandozzi CM, Jones JP.

J Med Chem. 2007 Sep 20;50(19):4642-7. Epub 2007 Aug 25.

PMID:
17718551
47.

[Infectivity and resistance to antibiotics of bacterial strains isolated from patients hospitalised in intensive care units].

Wojnicz D, Korzekwa K, Kakol A, Doroszkiewicz W.

Med Dosw Mikrobiol. 2007;59(1):75-84. Polish.

PMID:
17601034
48.

Empirical regioselectivity models for human cytochromes P450 3A4, 2D6, and 2C9.

Sheridan RP, Korzekwa KR, Torres RA, Walker MJ.

J Med Chem. 2007 Jul 12;50(14):3173-84. Epub 2007 Jun 19.

49.

Inhibition of recombinant cytochrome P450 isoforms 2D6 and 2C9 by diverse drug-like molecules.

McMasters DR, Torres RA, Crathern SJ, Dooney DL, Nachbar RB, Sheridan RP, Korzekwa KR.

J Med Chem. 2007 Jul 12;50(14):3205-13. Epub 2007 Jun 9.

50.

Superantigen types in Staphylococcus aureus isolated from patients with cystic fibrosis.

Bania J, Dabrowska A, Rózalska B, Sadowska B, Wieckowska-Szakiel M, Korzekwa K, Zarczyńska A, Bystroń J, Chrzanowska J, Molenda J.

Folia Microbiol (Praha). 2006;51(6):614-8.

PMID:
17455800

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