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Items: 1 to 50 of 63

1.

A potent Lassa virus antiviral targets an arenavirus virulence determinant.

Madu IG, Files M, Gharaibeh DN, Moore AL, Jung KH, Gowen BB, Dai D, Jones KF, Tyavanagimatt SR, Burgeson JR, Korth MJ, Bedard KM, Iadonato SP, Amberg SM.

PLoS Pathog. 2018 Dec 21;14(12):e1007439. doi: 10.1371/journal.ppat.1007439. eCollection 2018 Dec.

2.

Integrated Omics Analysis of Pathogenic Host Responses during Pandemic H1N1 Influenza Virus Infection: The Crucial Role of Lipid Metabolism.

Tisoncik-Go J, Gasper DJ, Kyle JE, Eisfeld AJ, Selinger C, Hatta M, Morrison J, Korth MJ, Zink EM, Kim YM, Schepmoes AA, Nicora CD, Purvine SO, Weitz KK, Peng X, Green RR, Tilton SC, Webb-Robertson BJ, Waters KM, Metz TO, Smith RD, Kawaoka Y, Suresh M, Josset L, Katze MG.

Cell Host Microbe. 2016 Feb 10;19(2):254-66. doi: 10.1016/j.chom.2016.01.002.

3.

Delayed inflammatory and cell death responses are associated with reduced pathogenicity in Lujo virus-infected cynomolgus macaques.

Rasmussen AL, Tchitchek N, Safronetz D, Carter VS, Williams CM, Haddock E, Korth MJ, Feldmann H, Katze MG.

J Virol. 2015 Mar;89(5):2543-52. doi: 10.1128/JVI.02246-14. Epub 2014 Dec 17.

4.

Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance.

Rasmussen AL, Okumura A, Ferris MT, Green R, Feldmann F, Kelly SM, Scott DP, Safronetz D, Haddock E, LaCasse R, Thomas MJ, Sova P, Carter VS, Weiss JM, Miller DR, Shaw GD, Korth MJ, Heise MT, Baric RS, de Villena FP, Feldmann H, Katze MG.

Science. 2014 Nov 21;346(6212):987-91. doi: 10.1126/science.1259595. Epub 2014 Oct 30.

5.

Deep sequencing of HIV-infected cells: insights into nascent transcription and host-directed therapy.

Peng X, Sova P, Green RR, Thomas MJ, Korth MJ, Proll S, Xu J, Cheng Y, Yi K, Chen L, Peng Z, Wang J, Palermo RE, Katze MG.

J Virol. 2014 Aug;88(16):8768-82. doi: 10.1128/JVI.00768-14. Epub 2014 May 21.

6.

Old world monkeys and new age science: the evolution of nonhuman primate systems virology.

Palermo RE, Tisoncik-Go J, Korth MJ, Katze MG.

ILAR J. 2013;54(2):166-80. doi: 10.1093/ilar/ilt039. Review.

7.

Drug repurposing: a better approach for infectious disease drug discovery?

Law GL, Tisoncik-Go J, Korth MJ, Katze MG.

Curr Opin Immunol. 2013 Oct;25(5):588-92. doi: 10.1016/j.coi.2013.08.004. Epub 2013 Sep 5. Review.

8.

Systems virology: host-directed approaches to viral pathogenesis and drug targeting.

Law GL, Korth MJ, Benecke AG, Katze MG.

Nat Rev Microbiol. 2013 Jul;11(7):455-66. doi: 10.1038/nrmicro3036. Epub 2013 Jun 3. Review.

9.

Systems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic viruses.

Korth MJ, Tchitchek N, Benecke AG, Katze MG.

Semin Immunol. 2013 Oct 31;25(3):228-39. doi: 10.1016/j.smim.2012.11.001. Epub 2012 Dec 5. Review.

10.

Chronic immune activation is a distinguishing feature of liver and PBMC gene signatures from HCV/HIV coinfected patients and may contribute to hepatic fibrogenesis.

Rasmussen AL, Wang IM, Shuhart MC, Proll SC, He Y, Cristescu R, Roberts C, Carter VS, Williams CM, Diamond DL, Bryan JT, Ulrich R, Korth MJ, Thomassen LV, Katze MG.

Virology. 2012 Aug 15;430(1):43-52. doi: 10.1016/j.virol.2012.04.011. Epub 2012 May 16.

11.

Quantitative proteomic analysis of HIV-1 infected CD4+ T cells reveals an early host response in important biological pathways: protein synthesis, cell proliferation, and T-cell activation.

Navare AT, Sova P, Purdy DE, Weiss JM, Wolf-Yadlin A, Korth MJ, Chang ST, Proll SC, Jahan TA, Krasnoselsky AL, Palermo RE, Katze MG.

Virology. 2012 Jul 20;429(1):37-46. doi: 10.1016/j.virol.2012.03.026. Epub 2012 Apr 26.

12.

Into the eye of the cytokine storm.

Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG.

Microbiol Mol Biol Rev. 2012 Mar;76(1):16-32. doi: 10.1128/MMBR.05015-11. Review.

13.

Early transcriptional programming links progression to hepatitis C virus-induced severe liver disease in transplant patients.

Rasmussen AL, Tchitchek N, Susnow NJ, Krasnoselsky AL, Diamond DL, Yeh MM, Proll SC, Korth MJ, Walters KA, Lederer S, Larson AM, Carithers RL, Benecke A, Katze MG.

Hepatology. 2012 Jul;56(1):17-27. doi: 10.1002/hep.25612. Epub 2012 Jun 5.

14.

Molecular signatures associated with Mx1-mediated resistance to highly pathogenic influenza virus infection: mechanisms of survival.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Carter VS, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2012 Mar;86(5):2437-46. doi: 10.1128/JVI.06156-11. Epub 2011 Dec 21.

15.

Integrative deep sequencing of the mouse lung transcriptome reveals differential expression of diverse classes of small RNAs in response to respiratory virus infection.

Peng X, Gralinski L, Ferris MT, Frieman MB, Thomas MJ, Proll S, Korth MJ, Tisoncik JR, Heise M, Luo S, Schroth GP, Tumpey TM, Li C, Kawaoka Y, Baric RS, Katze MG.

MBio. 2011 Nov 15;2(6). pii: e00198-11. doi: 10.1128/mBio.00198-11. Print 2011.

16.

Systems virology identifies a mitochondrial fatty acid oxidation enzyme, dodecenoyl coenzyme A delta isomerase, required for hepatitis C virus replication and likely pathogenesis.

Rasmussen AL, Diamond DL, McDermott JE, Gao X, Metz TO, Matzke MM, Carter VS, Belisle SE, Korth MJ, Waters KM, Smith RD, Katze MG.

J Virol. 2011 Nov;85(22):11646-54. doi: 10.1128/JVI.05605-11. Epub 2011 Sep 14.

17.

Functional genomics reveals the induction of inflammatory response and metalloproteinase gene expression during lethal Ebola virus infection.

Cilloniz C, Ebihara H, Ni C, Neumann G, Korth MJ, Kelly SM, Kawaoka Y, Feldmann H, Katze MG.

J Virol. 2011 Sep;85(17):9060-8. doi: 10.1128/JVI.00659-11. Epub 2011 Jul 6.

18.

The NS1 protein of influenza A virus suppresses interferon-regulated activation of antigen-presentation and immune-proteasome pathways.

Tisoncik JR, Billharz R, Burmakina S, Belisle SE, Proll SC, Korth MJ, García-Sastre A, Katze MG.

J Gen Virol. 2011 Sep;92(Pt 9):2093-104. doi: 10.1099/vir.0.032060-0. Epub 2011 May 18. Erratum in: J Gen Virol. 2011 Oct;92(Pt 10):2466. Garcíia-Sastre, Adolfo [corrected to García-Sastre, Adolfo].

19.

A systems biology approach to infectious disease research: innovating the pathogen-host research paradigm.

Aderem A, Adkins JN, Ansong C, Galagan J, Kaiser S, Korth MJ, Law GL, McDermott JG, Proll SC, Rosenberger C, Schoolnik G, Katze MG.

MBio. 2011 Mar 1;2(1):e00325-10. doi: 10.1128/mBio.00325-10.

20.

Pandemic swine-origin H1N1 influenza A virus isolates show heterogeneous virulence in macaques.

Safronetz D, Rockx B, Feldmann F, Belisle SE, Palermo RE, Brining D, Gardner D, Proll SC, Marzi A, Tsuda Y, Lacasse RA, Kercher L, York A, Korth MJ, Long D, Rosenke R, Shupert WL, Aranda CA, Mattoon JS, Kobasa D, Kobinger G, Li Y, Taubenberger JK, Richt JA, Parnell M, Ebihara H, Kawaoka Y, Katze MG, Feldmann H.

J Virol. 2011 Feb;85(3):1214-23. doi: 10.1128/JVI.01848-10. Epub 2010 Nov 17.

21.

Genomic analysis reveals pre- and postchallenge differences in a rhesus macaque AIDS vaccine trial: insights into mechanisms of vaccine efficacy.

Palermo RE, Patterson LJ, Aicher LD, Korth MJ, Robert-Guroff M, Katze MG.

J Virol. 2011 Jan;85(2):1099-116. doi: 10.1128/JVI.01522-10. Epub 2010 Nov 10.

22.

Unique signatures of long noncoding RNA expression in response to virus infection and altered innate immune signaling.

Peng X, Gralinski L, Armour CD, Ferris MT, Thomas MJ, Proll S, Bradel-Tretheway BG, Korth MJ, Castle JC, Biery MC, Bouzek HK, Haynor DR, Frieman MB, Heise M, Raymond CK, Baric RS, Katze MG.

MBio. 2010 Oct 26;1(5). pii: e00206-10. doi: 10.1128/mBio.00206-10.

23.

Genomic profiling of tumor necrosis factor alpha (TNF-alpha) receptor and interleukin-1 receptor knockout mice reveals a link between TNF-alpha signaling and increased severity of 1918 pandemic influenza virus infection.

Belisle SE, Tisoncik JR, Korth MJ, Carter VS, Proll SC, Swayne DE, Pantin-Jackwood M, Tumpey TM, Katze MG.

J Virol. 2010 Dec;84(24):12576-88. doi: 10.1128/JVI.01310-10. Epub 2010 Oct 6.

24.

Transcriptomic analysis reveals a mechanism for a prefibrotic phenotype in STAT1 knockout mice during severe acute respiratory syndrome coronavirus infection.

Zornetzer GA, Frieman MB, Rosenzweig E, Korth MJ, Page C, Baric RS, Katze MG.

J Virol. 2010 Nov;84(21):11297-309. doi: 10.1128/JVI.01130-10. Epub 2010 Aug 11.

25.

Lethal dissemination of H5N1 influenza virus is associated with dysregulation of inflammation and lipoxin signaling in a mouse model of infection.

Cilloniz C, Pantin-Jackwood MJ, Ni C, Goodman AG, Peng X, Proll SC, Carter VS, Rosenzweig ER, Szretter KJ, Katz JM, Korth MJ, Swayne DE, Tumpey TM, Katze MG.

J Virol. 2010 Aug;84(15):7613-24. doi: 10.1128/JVI.00553-10. Epub 2010 May 26.

26.

Is systems biology the key to preventing the next pandemic?

Tisoncik JR, Belisle SE, Diamond DL, Korth MJ, Katze MG.

Future Virol. 2009 Nov 1;4(6):553-561.

27.

The alpha/beta interferon receptor provides protection against influenza virus replication but is dispensable for inflammatory response signaling.

Goodman AG, Zeng H, Proll SC, Peng X, Cillóniz C, Carter VS, Korth MJ, Tumpey TM, Katze MG.

J Virol. 2010 Feb;84(4):2027-37. doi: 10.1128/JVI.01595-09. Epub 2009 Nov 25.

28.

Decoding the multifaceted HIV-1 virus-host interactome.

Chan EY, Korth MJ, Katze MG.

J Biol. 2009 Oct 13;8(9):84. doi: 10.1186/jbiol183.

29.

Lethal influenza virus infection in macaques is associated with early dysregulation of inflammatory related genes.

Cillóniz C, Shinya K, Peng X, Korth MJ, Proll SC, Aicher LD, Carter VS, Chang JH, Kobasa D, Feldmann F, Strong JE, Feldmann H, Kawaoka Y, Katze MG.

PLoS Pathog. 2009 Oct;5(10):e1000604. doi: 10.1371/journal.ppat.1000604. Epub 2009 Oct 2.

30.

The NS1 protein of the 1918 pandemic influenza virus blocks host interferon and lipid metabolism pathways.

Billharz R, Zeng H, Proll SC, Korth MJ, Lederer S, Albrecht R, Goodman AG, Rosenzweig E, Tumpey TM, García-Sastre A, Katze MG.

J Virol. 2009 Oct;83(20):10557-70. doi: 10.1128/JVI.00330-09. Epub 2009 Aug 12.

31.

Virus-host interactions: from systems biology to translational research.

Peng X, Chan EY, Li Y, Diamond DL, Korth MJ, Katze MG.

Curr Opin Microbiol. 2009 Aug;12(4):432-8. doi: 10.1016/j.mib.2009.06.003. Epub 2009 Jul 1. Review.

32.

P58(IPK): a novel "CIHD" member of the host innate defense response against pathogenic virus infection.

Goodman AG, Fornek JL, Medigeshi GR, Perrone LA, Peng X, Dyer MD, Proll SC, Knoblaugh SE, Carter VS, Korth MJ, Nelson JA, Tumpey TM, Katze MG.

PLoS Pathog. 2009 May;5(5):e1000438. doi: 10.1371/journal.ppat.1000438. Epub 2009 May 22.

33.

Innate immune modulation by RNA viruses: emerging insights from functional genomics.

Katze MG, Fornek JL, Palermo RE, Walters KA, Korth MJ.

Nat Rev Immunol. 2008 Aug;8(8):644-54. doi: 10.1038/nri2377. Review.

PMID:
18654572
34.

Use of functional genomics to understand influenza-host interactions.

Fornek JL, Korth MJ, Katze MG.

Adv Virus Res. 2007;70:81-100. Review.

PMID:
17765704
35.

Lost in the world of functional genomics, systems biology, and translational research: is there life after the Milstein award?

Katze MG, Korth MJ.

Cytokine Growth Factor Rev. 2007 Oct-Dec;18(5-6):441-50. Epub 2007 Jul 27. Review.

36.

High-density rhesus macaque oligonucleotide microarray design using early-stage rhesus genome sequence information and human genome annotations.

Wallace JC, Korth MJ, Paeper B, Proll SC, Thomas MJ, Magness CL, Iadonato SP, Nelson C, Katze MG.

BMC Genomics. 2007 Jan 23;8:28.

37.

The cellular protein P58IPK regulates influenza virus mRNA translation and replication through a PKR-mediated mechanism.

Goodman AG, Smith JA, Balachandran S, Perwitasari O, Proll SC, Thomas MJ, Korth MJ, Barber GN, Schiff LA, Katze MG.

J Virol. 2007 Mar;81(5):2221-30. Epub 2006 Dec 13.

38.

Hijacking of the host-cell response and translational control during influenza virus infection.

Kash JC, Goodman AG, Korth MJ, Katze MG.

Virus Res. 2006 Jul;119(1):111-20. Epub 2006 Apr 19. Review.

PMID:
16630668
39.

Functional gene analysis of individual response to challenge of SIVmac239 in M. mulatta PBMC culture.

Thomas MJ, Agy MB, Proll SC, Paeper BW, Li Y, Jensen KL, Korth MJ, Katze MG.

Virology. 2006 Apr 25;348(1):242-52. Epub 2006 Jan 23.

40.

Gene expression patterns that correlate with hepatitis C and early progression to fibrosis in liver transplant recipients.

Smith MW, Walters KA, Korth MJ, Fitzgibbon M, Proll S, Thompson JC, Yeh MM, Shuhart MC, Furlong JC, Cox PP, Thomas DL, Phillips JD, Kushner JP, Fausto N, Carithers RL Jr, Katze MG.

Gastroenterology. 2006 Jan;130(1):179-87.

PMID:
16401481
41.

Virus infection and the interferon response: a global view through functional genomics.

Korth MJ, Kash JC, Furlong JC, Katze MG.

Methods Mol Med. 2005;116:37-55. Review.

PMID:
16000853
42.

Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human.

Magness CL, Fellin PC, Thomas MJ, Korth MJ, Agy MB, Proll SC, Fitzgibbon M, Scherer CA, Miner DG, Katze MG, Iadonato SP.

Genome Biol. 2005;6(7):R60. Epub 2005 Jun 30.

43.

Pancreatic beta-cell failure and diabetes in mice with a deletion mutation of the endoplasmic reticulum molecular chaperone gene P58IPK.

Ladiges WC, Knoblaugh SE, Morton JF, Korth MJ, Sopher BL, Baskin CR, MacAuley A, Goodman AG, LeBoeuf RC, Katze MG.

Diabetes. 2005 Apr;54(4):1074-81.

45.

Hepatitis C virus and liver disease: global transcriptional profiling and identification of potential markers.

Smith MW, Yue ZN, Korth MJ, Do HA, Boix L, Fausto N, Bruix J, Carithers RL Jr, Katze MG.

Hepatology. 2003 Dec;38(6):1458-67.

PMID:
14647057
46.

Gene expression profiling of the cellular transcriptional network regulated by alpha/beta interferon and its partial attenuation by the hepatitis C virus nonstructural 5A protein.

Geiss GK, Carter VS, He Y, Kwieciszewski BK, Holzman T, Korth MJ, Lazaro CA, Fausto N, Bumgarner RE, Katze MG.

J Virol. 2003 Jun;77(11):6367-75.

47.

Unlocking the mysteries of virus-host interactions: does functional genomics hold the key?

Korth MJ, Katze MG.

Ann N Y Acad Sci. 2002 Dec;975:160-8.

PMID:
12538162
48.

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.

49.

P52rIPK regulates the molecular cochaperone P58IPK to mediate control of the RNA-dependent protein kinase in response to cytoplasmic stress.

Gale M Jr, Blakely CM, Darveau A, Romano PR, Korth MJ, Katze MG.

Biochemistry. 2002 Oct 1;41(39):11878-87.

PMID:
12269832
50.

[Synopsis of various electrophysiological tests in early glaucoma diagnosis--temporal and spatiotemporal contrast sensitivity, light- and color-contrast pattern-reversal electroretinogram, blue-yellow VEP].

Korth MJ, Jünemann AM, Horn FK, Bergua A, Cursiefen C, Velten I, Budde WM, Wisse M, Martus P.

Klin Monbl Augenheilkd. 2000 Jun;216(6):360-8. German.

PMID:
10919115

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