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Adjuvant Chemotherapy of Locally Advanced Colon Cancer: Final Results of a Randomized Trial Comparing 5-Fluorouracil and Folinic Acid with Folfiri.

Paschke S, Hebart H, Goeb R, Staib L, Fleck U, Henne-Bruns D, Sander S, Link KH, Kornmann M.

Visc Med. 2019 Apr;35(2):124-132. doi: 10.1159/000491648. Epub 2018 Oct 30.


A Blood-Based Multi Marker Assay Supports the Differential Diagnosis of Early-Stage Pancreatic Cancer.

Berger AW, Schwerdel D, Reinacher-Schick A, Uhl W, Algül H, Friess H, Janssen KP, König A, Ghadimi M, Gallmeier E, Bartsch DK, Geissler M, Staib L, Tannapfel A, Kleger A, Beutel A, Schulte LA, Kornmann M, Ettrich TJ, Seufferlein T.

Theranostics. 2019 Feb 12;9(5):1280-1287. doi: 10.7150/thno.29247. eCollection 2019.


BRM transcriptionally regulates miR-302a-3p to target SOCS5/STAT3 signaling axis to potentiate pancreatic cancer metastasis.

Zhang Z, Li J, Guo H, Wang F, Ma L, Du C, Wang Y, Wang Q, Kornmann M, Tian X, Yang Y.

Cancer Lett. 2019 May 1;449:215-225. doi: 10.1016/j.canlet.2019.02.031. Epub 2019 Feb 18.


Neoadjuvant plus adjuvant or only adjuvant nab-paclitaxel plus gemcitabine for resectable pancreatic cancer - the NEONAX trial (AIO-PAK-0313), a prospective, randomized, controlled, phase II study of the AIO pancreatic cancer group.

Ettrich TJ, Berger AW, Perkhofer L, Daum S, König A, Dickhut A, Wittel U, Wille K, Geissler M, Algül H, Gallmeier E, Atzpodien J, Kornmann M, Muche R, Prasnikar N, Tannapfel A, Reinacher-Schick A, Uhl W, Seufferlein T.

BMC Cancer. 2018 Dec 29;18(1):1298. doi: 10.1186/s12885-018-5183-y.


Overstaging: A Challenge in Rectal Cancer Treatment.

Scheele J, Schmidt SA, Tenzer S, Henne-Bruns D, Kornmann M.

Visc Med. 2018 Aug;34(4):301-306. doi: 10.1159/000488652. Epub 2018 Jul 31.


Are Colon and Rectal Cancer Two Different Tumor Entities? A Proposal to Abandon the Term Colorectal Cancer.

Paschke S, Jafarov S, Staib L, Kreuser ED, Maulbecker-Armstrong C, Roitman M, Holm T, Harris CC, Link KH, Kornmann M.

Int J Mol Sci. 2018 Aug 30;19(9). pii: E2577. doi: 10.3390/ijms19092577. Review.


Advantages of a multi-state approach in surgical research: how intermediate events and risk factor profile affect the prognosis of a patient with locally advanced rectal cancer.

Manzini G, Ettrich TJ, Kremer M, Kornmann M, Henne-Bruns D, Eikema DA, Schlattmann P, de Wreede LC.

BMC Med Res Methodol. 2018 Feb 13;18(1):23. doi: 10.1186/s12874-018-0476-z.


Long noncoding RNA H19 derived miR-675 regulates cell proliferation by down-regulating E2F-1 in human pancreatic ductal adenocarcinoma.

Ma L, Tian X, Guo H, Zhang Z, Du C, Wang F, Xie X, Gao H, Zhuang Y, Kornmann M, Gao H, Yang Y.

J Cancer. 2018 Jan 1;9(2):389-399. doi: 10.7150/jca.21347. eCollection 2018.


Long non-coding RNA MEG3 functions as a tumour suppressor and has prognostic predictive value in human pancreatic cancer.

Ma L, Wang F, Du C, Zhang Z, Guo H, Xie X, Gao H, Zhuang Y, Kornmann M, Gao H, Tian X, Yang Y.

Oncol Rep. 2018 Mar;39(3):1132-1140. doi: 10.3892/or.2018.6178. Epub 2018 Jan 2.


Growth and Bone Mineralization of Very Preterm Infants at Term Corrected Age in Relation to Different Nutritional Intakes in the Early Postnatal Period.

Körnmann MN, Christmann V, Gradussen CJW, Rodwell L, Gotthardt M, Van Goudoever JB, Van Heijst AFJ.

Nutrients. 2017 Dec 2;9(12). pii: E1318. doi: 10.3390/nu9121318.


BRM/SMARCA2 promotes the proliferation and chemoresistance of pancreatic cancer cells by targeting JAK2/STAT3 signaling.

Zhang Z, Wang F, Du C, Guo H, Ma L, Liu X, Kornmann M, Tian X, Yang Y.

Cancer Lett. 2017 Aug 28;402:213-224. doi: 10.1016/j.canlet.2017.05.006. Epub 2017 Jun 7.


Endogenously Expressed IL-4Rα Promotes the Malignant Phenotype of Human Pancreatic Cancer In Vitro and In Vivo.

Traub B, Sun L, Ma Y, Xu P, Lemke J, Paschke S, Henne-Bruns D, Knippschild U, Kornmann M.

Int J Mol Sci. 2017 Mar 28;18(4). pii: E716. doi: 10.3390/ijms18040716.


Changes in Biochemical Parameters of the Calcium-Phosphorus Homeostasis in Relation to Nutritional Intake in Very-Low-Birth-Weight Infants.

Christmann V, Gradussen CJ, Körnmann MN, Roeleveld N, van Goudoever JB, van Heijst AF.

Nutrients. 2016 Nov 29;8(12). pii: E764.


Challenging the limits in pancreatic surgery: A case report.

Lemke J, Schmidt SA, Kornmann M, Orend KH, Henne-Bruns D.

Int J Surg Case Rep. 2016;29:151-154. doi: 10.1016/j.ijscr.2016.10.062. Epub 2016 Nov 15.


Population Pharmacokinetics and Target Attainment of Ertapenem in Plasma and Tissue Assessed via Microdialysis in Morbidly Obese Patients after Laparoscopic Visceral Surgery.

Wittau M, Paschke S, Kurlbaum M, Scheele J, Ly NS, Hemper E, Kornmann M, Henne-Bruns D, Bulitta JB.

Antimicrob Agents Chemother. 2016 Dec 27;61(1). pii: e00952-16. doi: 10.1128/AAC.00952-16. Print 2017 Jan.


The long noncoding RNA H19 promotes cell proliferation via E2F-1 in pancreatic ductal adenocarcinoma.

Ma L, Tian X, Wang F, Zhang Z, Du C, Xie X, Kornmann M, Yang Y.

Cancer Biol Ther. 2016 Oct 2;17(10):1051-1061. Epub 2016 Aug 29.


Aberrant methylation of MUC1 and MUC4 promoters are potential prognostic biomarkers for pancreatic ductal adenocarcinomas.

Yokoyama S, Higashi M, Kitamoto S, Oeldorf M, Knippschild U, Kornmann M, Maemura K, Kurahara H, Wiest E, Hamada T, Kitazono I, Goto Y, Tasaki T, Hiraki T, Hatanaka K, Mataki Y, Taguchi H, Hashimoto S, Batra SK, Tanimoto A, Yonezawa S, Hollingsworth MA.

Oncotarget. 2016 Jul 5;7(27):42553-42565. doi: 10.18632/oncotarget.9924.


Survival and Prognostic Factors of Colorectal Liver Metastases After Surgical and Nonsurgical Treatment.

Lemke J, Cammerer G, Ganser J, Scheele J, Xu P, Sander S, Henne-Bruns D, Kornmann M.

Clin Colorectal Cancer. 2016 Dec;15(4):e183-e192. doi: 10.1016/j.clcc.2016.04.007. Epub 2016 May 7.


An Exceptional Cause of Epigastric Pain.

Schulte-Kemna L, Kornmann M, Kleger A.

Gastroenterology. 2016 Jun;150(7):e1-e2. doi: 10.1053/j.gastro.2016.02.002. Epub 2016 Apr 30. No abstract available.


Hedgehog Signaling Regulates Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem-Like Cells.

Wang F, Ma L, Zhang Z, Liu X, Gao H, Zhuang Y, Yang P, Kornmann M, Tian X, Yang Y.

J Cancer. 2016 Jan 20;7(4):408-17. doi: 10.7150/jca.13305. eCollection 2016.


Management of a giant perineal condylomata acuminata.

Hemper E, Wittau M, Lemke J, Kornmann M, Henne-Bruns D.

GMS Interdiscip Plast Reconstr Surg DGPW. 2016 Jan 21;5:Doc07. doi: 10.3205/iprs000086. eCollection 2016.


Ectopic spleen and liver hemangioma mimicking metastatic pancreatic neuroendocrine tumor.

Engler CC, Lemke J, Kornmann M, Barth TF, Schmidt SA, Henne-Bruns D.

Int J Surg Case Rep. 2015;17:139-42. doi: 10.1016/j.ijscr.2015.10.041. Epub 2015 Nov 6.


Stratified Survival Analysis After Adjuvant Chemotherapy of Colon Cancer Reveals a Benefit for Older Patients.

Mayer B, Sander S, Paschke S, Henne-Bruns D, Link KH, Kornmann M; Study Group Oncology of Gastrointestinal Tumors (FOGT).

Anticancer Res. 2015 Oct;35(10):5587-93.


In chordoma, metastasis, recurrences, Ki-67 index, and a matrix-poor phenotype are associated with patients' shorter overall survival.

von Witzleben A, Goerttler LT, Lennerz J, Weissinger S, Kornmann M, Mayer-Steinacker R, von Baer A, Schultheiss M, Möller P, Barth TF.

Eur Spine J. 2016 Dec;25(12):4016-4024. Epub 2015 Sep 23.


Preclinical Characterization of Novel Chordoma Cell Systems and Their Targeting by Pharmocological Inhibitors of the CDK4/6 Cell-Cycle Pathway.

von Witzleben A, Goerttler LT, Marienfeld R, Barth H, Lechel A, Mellert K, Böhm M, Kornmann M, Mayer-Steinacker R, von Baer A, Schultheiss M, Flanagan AM, Möller P, Brüderlein S, Barth TF.

Cancer Res. 2015 Sep 15;75(18):3823-31. doi: 10.1158/0008-5472.CAN-14-3270. Epub 2015 Jul 16.


Quality of Life After Sphincter-Preserving Rectal Cancer Resection.

Scheele J, Lemke J, Meier M, Sander S, Henne-Bruns D, Kornmann M.

Clin Colorectal Cancer. 2015 Dec;14(4):e33-40. doi: 10.1016/j.clcc.2015.05.012. Epub 2015 Jun 6.


Appendix carcinoid associated with the Peutz-Jeghers syndrome.

Hofmann S, Barth TF, Kornmann M, Henne-Bruns D.

Int J Surg Case Rep. 2014;5(12):964-7. doi: 10.1016/j.ijscr.2014.06.024. Epub 2014 Oct 27.


Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.

Richter J, Ullah K, Xu P, Alscher V, Blatz A, Peifer C, Halekotte J, Leban J, Vitt D, Holzmann K, Bakulev V, Pinna LA, Henne-Bruns D, Hillenbrand A, Kornmann M, Leithäuser F, Bischof J, Knippschild U.

Int J Cancer. 2015 Jun 15;136(12):2799-810. doi: 10.1002/ijc.29346. Epub 2014 Dec 1. Erratum in: Int J Cancer. 2016 Aug 15;139(4):E5.


Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial.

Thomaidis T, Maderer A, Formentini A, Bauer S, Trautmann M, Schwarz M, Neumann W, Kittner JM, Schad A, Link KH, Rey JW, Weinmann A, Hoffman A, Galle PR, Kornmann M, Moehler M.

J Exp Clin Cancer Res. 2014 Oct 2;33:83. doi: 10.1186/s13046-014-0083-8.


Brain metastases in gastrointestinal cancers: is there a role for surgery?

Lemke J, Scheele J, Kapapa T, von Karstedt S, Wirtz CR, Henne-Bruns D, Kornmann M.

Int J Mol Sci. 2014 Sep 22;15(9):16816-30. doi: 10.3390/ijms150916816. Review.


BRG1 promotes chemoresistance of pancreatic cancer cells through crosstalking with Akt signalling.

Liu X, Tian X, Wang F, Ma Y, Kornmann M, Yang Y.

Eur J Cancer. 2014 Sep;50(13):2251-62. doi: 10.1016/j.ejca.2014.05.017. Epub 2014 Jun 18.


Survival and prognostic factors in pancreatic and ampullary cancer.

Lemke J, Schäfer D, Sander S, Henne-Bruns D, Kornmann M.

Anticancer Res. 2014 Jun;34(6):3011-20.


Chondroid hamartoma of the liver.

Scheele J, Lemke J, Barth TF, Juchems M, Wittau M, Kornmann M, Henne-Bruns D.

GMS Interdiscip Plast Reconstr Surg DGPW. 2014 Dec 17;3:Doc16. doi: 10.3205/iprs000057. eCollection 2014.


Absence of FLICE-inhibitory protein is a novel independent prognostic marker for very short survival in pancreatic ductal adenocarcinoma.

Schmid SJ, Glatzel MC, Welke C, Kornmann M, Kleger A, Barth TF, Fulda S, Lennerz JK, Möller P.

Pancreas. 2013 Oct;42(7):1114-9. doi: 10.1097/MPA.0b013e31829655ed.


Multicenter phase II trial to investigate safety and efficacy of gemcitabine combined with cetuximab as adjuvant therapy in pancreatic cancer (ATIP).

Fensterer H, Schade-Brittinger C, Müller HH, Tebbe S, Fass J, Lindig U, Settmacher U, Schmidt WE, Märten A, Ebert MP, Kornmann M, Hofheinz R, Endlicher E, Brendel C, Barth PJ, Bartsch DK, Michl P, Gress TM; Arbeitsgemeinschaft Internistische Onkologie.

Ann Oncol. 2013 Oct;24(10):2576-81. doi: 10.1093/annonc/mdt270. Epub 2013 Jul 29.


Factors influencing the course of acute appendicitis in adults and children.

Tsioplis C, Brockschmidt C, Sander S, Henne-Bruns D, Kornmann M.

Langenbecks Arch Surg. 2013 Aug;398(6):857-67. doi: 10.1007/s00423-013-1096-z. Epub 2013 Jul 7.


Brain metastasis in pancreatic cancer.

Lemke J, Scheele J, Kapapa T, Wirtz CR, Henne-Bruns D, Kornmann M.

Int J Mol Sci. 2013 Feb 19;14(2):4163-73. doi: 10.3390/ijms14024163.


Long-term results of 2 adjuvant trials reveal differences in chemosensitivity and the pattern of metastases between colon cancer and rectal cancer.

Kornmann M, Staib L, Wiegel T, Kron M, Henne-Bruns D, Link KH, Formentini A; Study Group Oncology of Gastrointestinal Tumors (FOGT).

Clin Colorectal Cancer. 2013 Mar;12(1):54-61. doi: 10.1016/j.clcc.2012.07.005. Epub 2012 Oct 27.


Visual AIDS for multimodal treatment options to support decision making of patients with colorectal cancer.

Hofmann S, Vetter J, Wachter C, Henne-Bruns D, Porzsolt F, Kornmann M.

BMC Med Inform Decis Mak. 2012 Oct 23;12:118. doi: 10.1186/1472-6947-12-118.


Thymidylate synthase and cyclin D1 protein expression in lymph node negative colorectal cancer: role as prognostic factors?

Formentini A, Henne-Bruns D, Kornmann M.

Hepatogastroenterology. 2012 Sep;59(118):1859-64. doi: 10.5754/hge10428.


Inhibition of pancreatic cancer cell growth in vivo using a tetracycline-inducible cyclin D1 antisense expression system.

Wang JC, Thiere M, Henne-Bruns D, Knippschild U, Kornmann M.

Pancreas. 2013 Jan;42(1):141-8. doi: 10.1097/MPA.0b013e3182546de5.


Interactions of pancreatic cancer and stellate cells are mediated by FGFR1-III isoform expression.

Tian X, Chen G, Zhou S, Henne-Bruns D, Bachem M, Kornmann M.

Hepatogastroenterology. 2012 Jul-Aug;59(117):1604-8. doi: 10.5754/hge10366.


Evaluation of important prognostic clinical and pathological factors in gastric cancer.

Cammerer G, Formentini A, Karletshofer M, Henne-Bruns D, Kornmann M.

Anticancer Res. 2012 May;32(5):1839-42.


Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer.

Formentini A, Braun P, Fricke H, Link KH, Henne-Bruns D, Kornmann M.

Int J Colorectal Dis. 2012 Oct;27(10):1369-76. Epub 2012 Mar 24.


Cystic teratoma of the pancreas.

Scheele J, Barth TF, Wittau M, Juchems M, Henne-Bruns D, Kornmann M.

Anticancer Res. 2012 Mar;32(3):1075-80. Review.


Microsatellite instability and Beta2-Microglobulin mutations as prognostic markers in colon cancer: results of the FOGT-4 trial.

Tikidzhieva A, Benner A, Michel S, Formentini A, Link KH, Dippold W, von Knebel Doeberitz M, Kornmann M, Kloor M.

Br J Cancer. 2012 Mar 13;106(6):1239-45. doi: 10.1038/bjc.2012.53. Epub 2012 Feb 21.


Traumatic diaphragmatic ruptures: clinical presentation, diagnosis and surgical approach in adults.

Hofmann S, Kornmann M, Henne-Bruns D, Formentini A.

GMS Interdiscip Plast Reconstr Surg DGPW. 2012 Jan 9;1:Doc02. doi: 10.3205/iprs000002. eCollection 2012.


Long-term survival following resection of brain metastases from pancreatic cancer.

Lemke J, Barth TF, Juchems M, Kapapa T, Henne-Bruns D, Kornmann M.

Anticancer Res. 2011 Dec;31(12):4599-603.


Response prediction in metastasised colorectal cancer using intratumoural thymidylate synthase: results of a randomised multicentre trial.

Kornmann M, Hebart H, Danenberg K, Goeb R, Staib L, Kron M, Henne-Bruns D, Danenberg P, Link KH.

Eur J Cancer. 2012 Jul;48(10):1443-51. doi: 10.1016/j.ejca.2011.11.007. Epub 2011 Nov 29.


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