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Items: 1 to 50 of 127

1.

A slow transcription rate causes embryonic lethality and perturbs kinetic coupling of neuronal genes.

Maslon MM, Braunschweig U, Aitken S, Mann AR, Kilanowski F, Hunter CJ, Blencowe BJ, Kornblihtt AR, Adams IR, Cáceres JF.

EMBO J. 2019 May 2;38(9). pii: e101244. doi: 10.15252/embj.2018101244. Epub 2019 Apr 15.

2.

Alternative Splicing and Transcription Elongation in Plants.

Godoy Herz MA, Kornblihtt AR.

Front Plant Sci. 2019 Mar 26;10:309. doi: 10.3389/fpls.2019.00309. eCollection 2019. Review.

3.

Light Regulates Plant Alternative Splicing through the Control of Transcriptional Elongation.

Godoy Herz MA, Kubaczka MG, Brzyżek G, Servi L, Krzyszton M, Simpson C, Brown J, Swiezewski S, Petrillo E, Kornblihtt AR.

Mol Cell. 2019 Mar 7;73(5):1066-1074.e3. doi: 10.1016/j.molcel.2018.12.005. Epub 2019 Jan 17.

PMID:
30661982
4.

Epigenetics at the base of alternative splicing changes that promote colorectal cancer.

Kornblihtt AR.

J Clin Invest. 2017 Sep 1;127(9):3281-3283. doi: 10.1172/JCI96497. Epub 2017 Aug 21.

5.

Alternative splicing switches: Important players in cell differentiation.

Fiszbein A, Kornblihtt AR.

Bioessays. 2017 Jun;39(6). doi: 10.1002/bies.201600157. Epub 2017 Apr 27. Review.

PMID:
28452057
6.

Major Roles for Pyrimidine Dimers, Nucleotide Excision Repair, and ATR in the Alternative Splicing Response to UV Irradiation.

Muñoz MJ, Nieto Moreno N, Giono LE, Cambindo Botto AE, Dujardin G, Bastianello G, Lavore S, Torres-Méndez A, Menck CFM, Blencowe BJ, Irimia M, Foiani M, Kornblihtt AR.

Cell Rep. 2017 Mar 21;18(12):2868-2879. doi: 10.1016/j.celrep.2017.02.066.

7.

Histone methylation, alternative splicing and neuronal differentiation.

Fiszbein A, Kornblihtt AR.

Neurogenesis (Austin). 2016 Jun 23;3(1):e1204844. doi: 10.1080/23262133.2016.1204844. eCollection 2016.

8.

How Are Short Exons Flanked by Long Introns Defined and Committed to Splicing?

Hollander D, Naftelberg S, Lev-Maor G, Kornblihtt AR, Ast G.

Trends Genet. 2016 Oct;32(10):596-606. doi: 10.1016/j.tig.2016.07.003. Epub 2016 Aug 6. Review.

PMID:
27507607
9.

Alternative Splicing of G9a Regulates Neuronal Differentiation.

Fiszbein A, Giono LE, Quaglino A, Berardino BG, Sigaut L, von Bilderling C, Schor IE, Steinberg JH, Rossi M, Pietrasanta LI, Caramelo JJ, Srebrow A, Kornblihtt AR.

Cell Rep. 2016 Mar 29;14(12):2797-808. doi: 10.1016/j.celrep.2016.02.063. Epub 2016 Mar 17.

10.

The RNA Response to DNA Damage.

Giono LE, Nieto Moreno N, Cambindo Botto AE, Dujardin G, Muñoz MJ, Kornblihtt AR.

J Mol Biol. 2016 Jun 19;428(12):2636-2651. doi: 10.1016/j.jmb.2016.03.004. Epub 2016 Mar 12. Review.

PMID:
26979557
11.

Chromatin, DNA structure and alternative splicing.

Nieto Moreno N, Giono LE, Cambindo Botto AE, Muñoz MJ, Kornblihtt AR.

FEBS Lett. 2015 Nov 14;589(22):3370-8. doi: 10.1016/j.febslet.2015.08.002. Epub 2015 Aug 18. Review.

12.

Regulation of alternative splicing through coupling with transcription and chromatin structure.

Naftelberg S, Schor IE, Ast G, Kornblihtt AR.

Annu Rev Biochem. 2015;84:165-98. doi: 10.1146/annurev-biochem-060614-034242. Review.

PMID:
26034889
13.

A bumpy road for RNA polymerase II.

Giono LE, Kornblihtt AR.

Nat Struct Mol Biol. 2015 May;22(5):353-5. doi: 10.1038/nsmb.3020. No abstract available.

PMID:
25945884
14.

A chromatin code for alternative splicing involving a putative association between CTCF and HP1α proteins.

Agirre E, Bellora N, Alló M, Pagès A, Bertucci P, Kornblihtt AR, Eyras E.

BMC Biol. 2015 May 2;13:31. doi: 10.1186/s12915-015-0141-5.

15.

Effects of airborne particulate matter on alternative pre-mRNA splicing in colon cancer cells.

Buggiano V, Petrillo E, Alló M, Lafaille C, Redal MA, Alghamdi MA, Khoder MI, Shamy M, Muñoz MJ, Kornblihtt AR.

Environ Res. 2015 Jul;140:185-90. doi: 10.1016/j.envres.2015.04.001. Epub 2015 Apr 9.

PMID:
25863591
16.

Transcriptional control of alternative splicing along time: ideas change, experiments remain.

Kornblihtt AR.

RNA. 2015 Apr;21(4):670-2. doi: 10.1261/rna.051151.115. No abstract available.

17.

Long range chromatin organization: a new layer in splicing regulation?

Acuña LI, Kornblihtt AR.

Transcription. 2014;5(3):e28726. doi: 10.4161/trns.28726.

18.

Let there be light: regulation of gene expression in plants.

Petrillo E, Godoy Herz MA, Barta A, Kalyna M, Kornblihtt AR.

RNA Biol. 2014;11(10):1215-20. doi: 10.4161/15476286.2014.972852.

19.

Shedding light on the chloroplast as a remote control of nuclear gene expression.

Godoy Herz MA, Kornblihtt AR, Barta A, Kalyna M, Petrillo E.

Plant Signal Behav. 2014;9(11):e976150. doi: 10.4161/15592324.2014.976150. Review.

20.

[Kinetic regulation of pre-messenger RNA alternative splicing].

Dujardin G, Kornblihtt AR, Corcos L.

Med Sci (Paris). 2014 Nov;30(11):940-3. doi: 10.1051/medsci/20143011003. Epub 2014 Nov 10. French. No abstract available.

21.

Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells.

Alló M, Agirre E, Bessonov S, Bertucci P, Gómez Acuña L, Buggiano V, Bellora N, Singh B, Petrillo E, Blaustein M, Miñana B, Dujardin G, Pozzi B, Pelisch F, Bechara E, Agafonov DE, Srebrow A, Lührmann R, Valcárcel J, Eyras E, Kornblihtt AR.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15622-9. doi: 10.1073/pnas.1416858111. Epub 2014 Oct 13.

22.

A long noncoding way to alternative splicing in plant development.

Kornblihtt AR.

Dev Cell. 2014 Jul 28;30(2):117-9. doi: 10.1016/j.devcel.2014.07.010.

23.

How slow RNA polymerase II elongation favors alternative exon skipping.

Dujardin G, Lafaille C, de la Mata M, Marasco LE, Muñoz MJ, Le Jossic-Corcos C, Corcos L, Kornblihtt AR.

Mol Cell. 2014 May 22;54(4):683-90. doi: 10.1016/j.molcel.2014.03.044. Epub 2014 May 1.

24.

A chloroplast retrograde signal regulates nuclear alternative splicing.

Petrillo E, Godoy Herz MA, Fuchs A, Reifer D, Fuller J, Yanovsky MJ, Simpson C, Brown JW, Barta A, Kalyna M, Kornblihtt AR.

Science. 2014 Apr 25;344(6182):427-30. doi: 10.1126/science.1250322. Epub 2014 Apr 10.

25.

The transcription factor FBI-1 inhibits SAM68-mediated BCL-X alternative splicing and apoptosis.

Bielli P, Busà R, Di Stasi SM, Munoz MJ, Botti F, Kornblihtt AR, Sette C.

EMBO Rep. 2014 Apr;15(4):419-27. doi: 10.1002/embr.201338241. Epub 2014 Feb 10.

26.

Coupling between transcription and alternative splicing.

Schor IE, Gómez Acuña LI, Kornblihtt AR.

Cancer Treat Res. 2013;158:1-24. doi: 10.1007/978-3-642-31659-3_1.

PMID:
24222352
27.

Intragenic epigenetic changes modulate NCAM alternative splicing in neuronal differentiation.

Schor IE, Fiszbein A, Petrillo E, Kornblihtt AR.

EMBO J. 2013 Aug 14;32(16):2264-74. doi: 10.1038/emboj.2013.167. Epub 2013 Jul 26.

28.

Progesterone receptor induces bcl-x expression through intragenic binding sites favoring RNA polymerase II elongation.

Bertucci PY, Nacht AS, Alló M, Rocha-Viegas L, Ballaré C, Soronellas D, Castellano G, Zaurin R, Kornblihtt AR, Beato M, Vicent GP, Pecci A.

Nucleic Acids Res. 2013 Jul;41(12):6072-86. doi: 10.1093/nar/gkt327. Epub 2013 May 2.

29.

Alternative splicing: a pivotal step between eukaryotic transcription and translation.

Kornblihtt AR, Schor IE, Alló M, Dujardin G, Petrillo E, Muñoz MJ.

Nat Rev Mol Cell Biol. 2013 Mar;14(3):153-65. doi: 10.1038/nrm3525. Epub 2013 Feb 6. Review. Erratum in: Nat Rev Mol Cell Biol. 2013 Mar;14(3). doi:10.1038/nrm3560.

PMID:
23385723
30.

Perturbation of chromatin structure globally affects localization and recruitment of splicing factors.

Schor IE, Llères D, Risso GJ, Pawellek A, Ule J, Lamond AI, Kornblihtt AR.

PLoS One. 2012;7(11):e48084. doi: 10.1371/journal.pone.0048084. Epub 2012 Nov 12.

31.

Connections between chromatin signatures and splicing.

Gómez Acuña LI, Fiszbein A, Alló M, Schor IE, Kornblihtt AR.

Wiley Interdiscip Rev RNA. 2013 Jan-Feb;4(1):77-91. doi: 10.1002/wrna.1142. Epub 2012 Oct 16. Review.

PMID:
23074139
32.

Transcriptional elongation and alternative splicing.

Dujardin G, Lafaille C, Petrillo E, Buggiano V, Gómez Acuña LI, Fiszbein A, Godoy Herz MA, Nieto Moreno N, Muñoz MJ, Alló M, Schor IE, Kornblihtt AR.

Biochim Biophys Acta. 2013 Jan;1829(1):134-40. doi: 10.1016/j.bbagrm.2012.08.005. Epub 2012 Sep 7. Review.

PMID:
22975042
33.

CTCF: from insulators to alternative splicing regulation.

Kornblihtt AR.

Cell Res. 2012 Mar;22(3):450-2. doi: 10.1038/cr.2012.22. Epub 2012 Feb 7. No abstract available.

34.

Alternative splicing adds a new loop to the circadian clock.

Petrillo E, Sanchez SE, Kornblihtt AR, Yanovsky MJ.

Commun Integr Biol. 2011 May;4(3):284-286. doi: 10.4161/cib.4.3.14777.

35.

Alternative splicing at the right time.

Sanchez SE, Petrillo E, Kornblihtt AR, Yanovsky MJ.

RNA Biol. 2011 Nov-Dec;8(6):954-9. doi: 10.4161/rna.8.6.17336. Epub 2011 Nov 1. Review.

36.

Chromatin and alternative splicing.

Alló M, Schor IE, Muñoz MJ, de la Mata M, Agirre E, Valcárcel J, Eyras E, Kornblihtt AR.

Cold Spring Harb Symp Quant Biol. 2010;75:103-11. doi: 10.1101/sqb.2010.75.023. Epub 2011 Feb 2.

PMID:
21289049
37.

Epigenetics in alternative pre-mRNA splicing.

Luco RF, Allo M, Schor IE, Kornblihtt AR, Misteli T.

Cell. 2011 Jan 7;144(1):16-26. doi: 10.1016/j.cell.2010.11.056. Review.

38.

RNA Polymerase II Elongation at the Crossroads of Transcription and Alternative Splicing.

de la Mata M, Muñoz MJ, Alló M, Fededa JP, Schor IE, Kornblihtt AR.

Genet Res Int. 2011;2011:309865. doi: 10.4061/2011/309865. Epub 2011 Sep 20.

39.

A methyl transferase links the circadian clock to the regulation of alternative splicing.

Sanchez SE, Petrillo E, Beckwith EJ, Zhang X, Rugnone ML, Hernando CE, Cuevas JC, Godoy Herz MA, Depetris-Chauvin A, Simpson CG, Brown JW, Cerdán PD, Borevitz JO, Mas P, Ceriani MF, Kornblihtt AR, Yanovsky MJ.

Nature. 2010 Nov 4;468(7320):112-6. doi: 10.1038/nature09470. Epub 2010 Oct 20.

PMID:
20962777
40.

Gene silencing: small RNAs control RNA polymerase II elongation.

Alló M, Kornblihtt AR.

Curr Biol. 2010 Sep 14;20(17):R704-7. doi: 10.1016/j.cub.2010.07.013.

41.

Characterization of specific cDNA background synthesis introduced by reverse transcription in RT-PCR assays.

Adrover MF, Muñoz MJ, Baez MV, Thomas J, Kornblihtt AR, Epstein AL, Jerusalinsky DA.

Biochimie. 2010 Dec;92(12):1839-46. doi: 10.1016/j.biochi.2010.07.019. Epub 2010 Aug 13.

PMID:
20709138
42.

The carboxy terminal domain of RNA polymerase II and alternative splicing.

Muñoz MJ, de la Mata M, Kornblihtt AR.

Trends Biochem Sci. 2010 Sep;35(9):497-504. doi: 10.1016/j.tibs.2010.03.010. Epub 2010 Apr 24. Review.

PMID:
20418102
43.

First come, first served revisited: factors affecting the same alternative splicing event have different effects on the relative rates of intron removal.

de la Mata M, Lafaille C, Kornblihtt AR.

RNA. 2010 May;16(5):904-12. doi: 10.1261/rna.1993510. Epub 2010 Mar 31.

44.

Intragenic chromatin modifications: a new layer in alternative splicing regulation.

Schor IE, Alló M, Kornblihtt AR.

Epigenetics. 2010 Apr;5(3):174-9. Epub 2010 Apr 1.

PMID:
20224298
45.

When chromatin meets splicing.

Kornblihtt AR, Schor IE, Allo M, Blencowe BJ.

Nat Struct Mol Biol. 2009 Sep;16(9):902-3. No abstract available.

PMID:
19739285
47.

Control of alternative splicing through siRNA-mediated transcriptional gene silencing.

Alló M, Buggiano V, Fededa JP, Petrillo E, Schor I, de la Mata M, Agirre E, Plass M, Eyras E, Elela SA, Klinck R, Chabot B, Kornblihtt AR.

Nat Struct Mol Biol. 2009 Jul;16(7):717-24. doi: 10.1038/nsmb.1620. Epub 2009 Jun 21.

PMID:
19543290
48.

DNA damage regulates alternative splicing through inhibition of RNA polymerase II elongation.

Muñoz MJ, Pérez Santangelo MS, Paronetto MP, de la Mata M, Pelisch F, Boireau S, Glover-Cutter K, Ben-Dov C, Blaustein M, Lozano JJ, Bird G, Bentley D, Bertrand E, Kornblihtt AR.

Cell. 2009 May 15;137(4):708-20. doi: 10.1016/j.cell.2009.03.010. Erratum in: Cell. 2009 Oct 2;139(1):211.

49.

Neuronal cell depolarization induces intragenic chromatin modifications affecting NCAM alternative splicing.

Schor IE, Rascovan N, Pelisch F, Alló M, Kornblihtt AR.

Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4325-30. doi: 10.1073/pnas.0810666106. Epub 2009 Feb 26.

50.

A splicing regulator promotes transcriptional elongation.

Fededa JP, Kornblihtt AR.

Nat Struct Mol Biol. 2008 Aug;15(8):779-81. doi: 10.1038/nsmb0808-779. No abstract available.

PMID:
18679431

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