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Items: 1 to 50 of 279

1.

Polymerization pathway of mammalian nonmuscle myosin 2s.

Liu X, Shu S, Korn ED.

Proc Natl Acad Sci U S A. 2018 Jul 11. pii: 201808800. doi: 10.1073/pnas.1808800115. [Epub ahead of print]

PMID:
29997172
2.

Interacting-heads motif has been conserved as a mechanism of myosin II inhibition since before the origin of animals.

Lee KH, Sulbarán G, Yang S, Mun JY, Alamo L, Pinto A, Sato O, Ikebe M, Liu X, Korn ED, Sarsoza F, Bernstein SI, Padrón R, Craig R.

Proc Natl Acad Sci U S A. 2018 Feb 27;115(9):E1991-E2000. doi: 10.1073/pnas.1715247115. Epub 2018 Feb 14.

PMID:
29444861
3.

Effect of ATP and regulatory light-chain phosphorylation on the polymerization of mammalian nonmuscle myosin II.

Liu X, Billington N, Shu S, Yu SH, Piszczek G, Sellers JR, Korn ED.

Proc Natl Acad Sci U S A. 2017 Aug 8;114(32):E6516-E6525. doi: 10.1073/pnas.1702375114. Epub 2017 Jul 24.

4.

Mammalian Nonmuscle Myosin II Binds to Anionic Phospholipids with Concomitant Dissociation of the Regulatory Light Chain.

Liu X, Shu S, Billington N, Williamson CD, Yu S, Brzeska H, Donaldson JG, Sellers JR, Korn ED.

J Biol Chem. 2016 Nov 25;291(48):24828-24837. Epub 2016 Oct 3.

5.

Selective localization of myosin-I proteins in macropinosomes and actin waves.

Brzeska H, Koech H, Pridham KJ, Korn ED, Titus MA.

Cytoskeleton (Hoboken). 2016 Feb;73(2):68-82. doi: 10.1002/cm.21275. Epub 2016 Feb 22.

6.

Biochemical and biological properties of cortexillin III, a component of Dictyostelium DGAP1-cortexillin complexes.

Liu X, Shu S, Yu S, Lee DY, Piszczek G, Gucek M, Wang G, Korn ED.

Mol Biol Cell. 2014 Jul 1;25(13):2026-38. doi: 10.1091/mbc.E13-08-0457. Epub 2014 May 7.

7.

The association of myosin IB with actin waves in dictyostelium requires both the plasma membrane-binding site and actin-binding region in the myosin tail.

Brzeska H, Pridham K, Chery G, Titus MA, Korn ED.

PLoS One. 2014 Apr 18;9(4):e94306. doi: 10.1371/journal.pone.0094306. eCollection 2014.

8.

Kinetic characterization of the ATPase and actin-activated ATPase activities of Acanthamoeba castellanii myosin-2.

Heissler SM, Liu X, Korn ED, Sellers JR.

J Biol Chem. 2013 Sep 13;288(37):26709-20. doi: 10.1074/jbc.M113.485946. Epub 2013 Jul 29.

9.

Regulation of the filament structure and assembly of Acanthamoeba myosin II by phosphorylation of serines in the heavy-chain nonhelical tailpiece.

Liu X, Hong MS, Shu S, Yu S, Korn ED.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):E33-40. doi: 10.1073/pnas.1219727110. Epub 2012 Dec 17.

10.

Regulation of the actin-activated MgATPase activity of Acanthamoeba myosin II by phosphorylation of serine 639 in motor domain loop 2.

Liu X, Lee DY, Cai S, Yu S, Shu S, Levine RL, Korn ED.

Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):E23-32. doi: 10.1073/pnas.1219713110. Epub 2012 Dec 17.

11.

Molecular basis of dynamic relocalization of Dictyostelium myosin IB.

Brzeska H, Guag J, Preston GM, Titus MA, Korn ED.

J Biol Chem. 2012 Apr 27;287(18):14923-36. doi: 10.1074/jbc.M111.318667. Epub 2012 Feb 24.

12.

Actin cross-linking proteins cortexillin I and II are required for cAMP signaling during Dictyostelium chemotaxis and development.

Shu S, Liu X, Kriebel PW, Daniels MP, Korn ED.

Mol Biol Cell. 2012 Jan;23(2):390-400. doi: 10.1091/mbc.E11-09-0764. Epub 2011 Nov 23.

13.

Expression of Y53A-actin in Dictyostelium disrupts the cytoskeleton and inhibits intracellular and intercellular chemotactic signaling.

Shu S, Liu X, Kriebel PW, Hong MS, Daniels MP, Parent CA, Korn ED.

J Biol Chem. 2010 Sep 3;285(36):27713-25. doi: 10.1074/jbc.M110.116277. Epub 2010 Jul 7.

14.

Mutation of actin Tyr-53 alters the conformations of the DNase I-binding loop and the nucleotide-binding cleft.

Liu X, Shu S, Hong MS, Yu B, Korn ED.

J Biol Chem. 2010 Mar 26;285(13):9729-39. doi: 10.1074/jbc.M109.073452. Epub 2010 Jan 25.

15.

An experimentally based computer search identifies unstructured membrane-binding sites in proteins: application to class I myosins, PAKS, and CARMIL.

Brzeska H, Guag J, Remmert K, Chacko S, Korn ED.

J Biol Chem. 2010 Feb 19;285(8):5738-47. doi: 10.1074/jbc.M109.066910. Epub 2009 Dec 15.

16.

Acanthamoeba myosin IC colocalizes with phosphatidylinositol 4,5-bisphosphate at the plasma membrane due to the high concentration of negative charge.

Brzeska H, Hwang KJ, Korn ED.

J Biol Chem. 2008 Nov 14;283(46):32014-23. doi: 10.1074/jbc.M804828200. Epub 2008 Sep 4.

17.

Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.

Baek K, Liu X, Ferron F, Shu S, Korn ED, Dominguez R.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11748-53. doi: 10.1073/pnas.0805852105. Epub 2008 Aug 8.

18.

Intramolecular interaction in the tail of Acanthamoeba myosin IC between the SH3 domain and a putative pleckstrin homology domain.

Hwang KJ, Mahmoodian F, Ferretti JA, Korn ED, Gruschus JM.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):784-9. Epub 2007 Jan 10.

19.

S-adenosylhomocysteine hydrolase is localized at the front of chemotaxing cells, suggesting a role for transmethylation during migration.

Shu S, Mahadeo DC, Liu X, Liu W, Parent CA, Korn ED.

Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19788-93. Epub 2006 Dec 15.

20.

Phosphorylation of actin Tyr-53 inhibits filament nucleation and elongation and destabilizes filaments.

Liu X, Shu S, Hong MS, Levine RL, Korn ED.

Proc Natl Acad Sci U S A. 2006 Sep 12;103(37):13694-9. Epub 2006 Aug 30.

21.

Activation of myosin in HeLa cells causes redistribution of focal adhesions and F-actin from cell center to cell periphery.

Szczepanowska J, Korn ED, Brzeska H.

Cell Motil Cytoskeleton. 2006 Jun;63(6):356-74.

PMID:
16607629
22.
23.

Blebbistatin and blebbistatin-inactivated myosin II inhibit myosin II-independent processes in Dictyostelium.

Shu S, Liu X, Korn ED.

Proc Natl Acad Sci U S A. 2005 Feb 1;102(5):1472-7. Epub 2005 Jan 25.

24.

Subdomain organization of the Acanthamoeba myosin IC tail from cryo-electron microscopy.

Ishikawa T, Cheng N, Liu X, Korn ED, Steven AC.

Proc Natl Acad Sci U S A. 2004 Aug 17;101(33):12189-94. Epub 2004 Aug 9.

25.

Rac-induced increase of phosphorylation of myosin regulatory light chain in HeLa cells.

Brzeska H, Szczepanowska J, Matsumura F, Korn ED.

Cell Motil Cytoskeleton. 2004 Jul;58(3):186-99.

PMID:
15146537
26.

The discovery of unconventional myosins: serendipity or luck?

Korn ED.

J Biol Chem. 2004 Mar 5;279(10):8517-25. Epub 2004 Jan 14. No abstract available.

27.

Dictyostelium and Acanthamoeba myosin II assembly domains go to the cleavage furrow of Dictyostelium myosin II-null cells.

Shu S, Liu X, Korn ED.

Proc Natl Acad Sci U S A. 2003 May 27;100(11):6499-504. Epub 2003 May 14.

28.

Dynamic localization of myosin-I to endocytic structures in Acanthamoeba.

Ostap EM, Maupin P, Doberstein SK, Baines IC, Korn ED, Pollard TD.

Cell Motil Cytoskeleton. 2003 Jan;54(1):29-40.

PMID:
12451593
29.

Tail chimeras of Dictyostelium myosin II support cytokinesis and other myosin II activities but not full development.

Shu S, Liu X, Parent CA, Uyeda TQ, Korn ED.

J Cell Sci. 2002 Nov 15;115(Pt 22):4237-49.

30.

Myosin-I nomenclature.

Gillespie PG, Albanesi JP, Bahler M, Bement WM, Berg JS, Burgess DR, Burnside B, Cheney RE, Corey DP, Coudrier E, de Lanerolle P, Hammer JA, Hasson T, Holt JR, Hudspeth AJ, Ikebe M, Kendrick-Jones J, Korn ED, Li R, Mercer JA, Milligan RA, Mooseker MS, Ostap EM, Petit C, Pollard TD, Sellers JR, Soldati T, Titus MA.

J Cell Biol. 2001 Nov 26;155(5):703-4. Epub 2001 Nov 26.

31.

Calmodulin-binding and autoinhibitory domains of Acanthamoeba myosin I heavy chain kinase, a p21-activated kinase (PAK).

Brzeska H, Young R, Tan C, Szczepanowska J, Korn ED.

J Biol Chem. 2001 Dec 14;276(50):47468-73. Epub 2001 Sep 28.

32.

Myosin I mutants with only 1% of wild-type actin-activated MgATPase activity retain essential in vivo function(s).

Liu X, Osherov N, Yamashita R, Brzeska H, Korn ED, May GS.

Proc Natl Acad Sci U S A. 2001 Jul 31;98(16):9122-7. Epub 2001 Jul 17.

33.

Coevolution of head, neck, and tail domains of myosin heavy chains.

Korn ED.

Proc Natl Acad Sci U S A. 2000 Nov 7;97(23):12559-64.

35.
36.

Flexibility of Acanthamoeba myosin rod minifilaments.

Redowicz MJ, Hammer JA 3rd, Bowers B, Zolkiewski M, Ginsburg A, Korn ED, Rau DC.

Biochemistry. 1999 Jun 1;38(22):7243-52.

PMID:
10353836
37.

Myosin I heavy chain kinase: cloning of the full-length gene and acidic lipid-dependent activation by Rac and Cdc42.

Brzeska H, Young R, Knaus U, Korn ED.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):394-9.

38.

Structural invariance of constitutively active and inactive mutants of acanthamoeba myosin IC bound to F-actin in the rigor and ADP-bound states.

Carragher BO, Cheng N, Wang ZY, Korn ED, Reilein A, Belnap DM, Hammer JA 3rd, Steven AC.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15206-11.

39.

Analysis of the regulatory phosphorylation site in Acanthamoeba myosin IC by using site-directed mutagenesis.

Wang ZY, Wang F, Sellers JR, Korn ED, Hammer JA 3rd.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15200-5.

40.

Effect of mutating the regulatory phosphoserine and conserved threonine on the activity of the expressed catalytic domain of Acanthamoeba myosin I heavy chain kinase.

Szczepanowska J, Ramachandran U, Herring CJ, Gruschus JM, Qin J, Korn ED, Brzeska H.

Proc Natl Acad Sci U S A. 1998 Apr 14;95(8):4146-51.

41.
42.

Identification by mass spectrometry of the phosphorylated residue responsible for activation of the catalytic domain of myosin I heavy chain kinase, a member of the PAK/STE20 family.

Szczepanowska J, Zhang X, Herring CJ, Qin J, Korn ED, Brzeska H.

Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8503-8. Erratum in: Proc Natl Acad Sci U S A 1997 Oct 28;94(22):12241.

43.

Two-state thermal unfolding of a long dimeric coiled-coil: the Acanthamoeba myosin II rod.

Zolkiewski M, Redowicz MJ, Korn ED, Hammer JA 3rd, Ginsburg A.

Biochemistry. 1997 Jun 24;36(25):7876-83.

PMID:
9201932
44.

The amino acid sequence of the light chain of Acanthamoeba myosin IC.

Wang ZY, Sakai J, Matsudaira PT, Baines IC, Sellers JR, Hammer JA 3rd, Korn ED.

J Muscle Res Cell Motil. 1997 Jun;18(3):395-8.

PMID:
9172081
45.

p21-activated kinase has substrate specificity similar to Acanthamoeba myosin I heavy chain kinase and activates Acanthamoeba myosin I.

Brzeska H, Knaus UG, Wang ZY, Bokoch GM, Korn ED.

Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1092-5.

49.

Regulation of class I and class II myosins by heavy chain phosphorylation.

Brzeska H, Korn ED.

J Biol Chem. 1996 Jul 19;271(29):16983-6. Review. No abstract available.

50.

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