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Items: 1 to 50 of 105

1.

Premedication with a cathepsin C inhibitor alleviates early primary graft dysfunction in mouse recipients after lung transplantation.

Rehm SRT, Smirnova NF, Morrone C, Götzfried J, Feuchtinger A, Pedersen J, Korkmaz B, Yildirim AÖ, Jenne DE.

Sci Rep. 2019 Jul 9;9(1):9925. doi: 10.1038/s41598-019-46206-8.

2.

Antimicrobial activity and volatile constituent analysis of three commercial herbal toothpastes containing Aloe vera L. and Fragaria vesca L. extracts.

Korkmaz FM, Ozel MB, Tuzuner T, Korkmaz B, Yayli N.

Niger J Clin Pract. 2019 May;22(5):718-726. doi: 10.4103/njcp.njcp_557_18.

3.

Structure-based design and in vivo anti-arthritic activity evaluation of a potent dipeptidyl cyclopropyl nitrile inhibitor of cathepsin C.

Korkmaz B, Lesner A, Wysocka M, Gieldon A, Håkansson M, Gauthier F, Logan DT, Jenne DE, Lauritzen C, Pedersen J.

Biochem Pharmacol. 2019 Jun;164:349-367. doi: 10.1016/j.bcp.2019.04.006. Epub 2019 Apr 9.

PMID:
30978322
4.

Diffuse large B-cell lymphoma presenting with masses in the pineal and adrenal glands.

Bilgin C, Korkmaz B, Soylu E, Ozturk H, Ozturk K.

Clin Case Rep. 2019 Jan 29;7(3):577-579. doi: 10.1002/ccr3.2016. eCollection 2019 Mar.

5.

Proteinase 3 phosphonic inhibitors.

Grzywa R, Lesner A, Korkmaz B, Sieńczyk M.

Biochimie. 2019 Mar 13. pii: S0300-9084(19)30072-0. doi: 10.1016/j.biochi.2019.03.005. [Epub ahead of print]

PMID:
30876969
6.

Improved decision-making and psychophysiological responses in mesial temporal lobe epilepsy after anterior temporal lobectomy.

Sandor S, Delil Ş, Yağcı S, Korkmaz B, Yeni SN.

Epileptic Disord. 2018 Dec 1;20(6):517-524. doi: 10.1684/epd.2018.1019.

PMID:
30530428
7.

NF-κB activation mediates LPS-or zymosan-induced hypotension and inflammation reversed by BAY61-3606, a selective Syk inhibitor, in rat models of septic and non-septic shock.

Sahan-Firat S, Temiz-Resitoglu M, Guden DS, Senol SP, Sari AN, Cil M, Unsal D, Korkmaz B, Tunctan B, Malik KU, Buharalioglu CK.

Clin Exp Pharmacol Physiol. 2019 Feb;46(2):173-182. doi: 10.1111/1440-1681.13045.

PMID:
30347478
8.

α-Glucosidase inhibitory effects of polyphenols from Geranium asphodeloides: Inhibition kinetics and mechanistic insights through in vitro and in silico studies.

Renda G, Sari S, Barut B, Šoral M, Liptaj T, Korkmaz B, Özel A, Erik İ, Şöhretoğlu D.

Bioorg Chem. 2018 Dec;81:545-552. doi: 10.1016/j.bioorg.2018.09.009. Epub 2018 Sep 12.

PMID:
30245236
9.

Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.

Seren S, Rashed Abouzaid M, Eulenberg-Gustavus C, Hirschfeld J, Nasr Soliman H, Jerke U, N'Guessan K, Dallet-Choisy S, Lesner A, Lauritzen C, Schacher B, Eickholz P, Nagy N, Szell M, Croix C, Viaud-Massuard MC, Al Farraj Aldosari A, Ragunatha S, Ibrahim Mostafa M, Giampieri F, Battino M, Cornillier H, Lorette G, Stephan JL, Goizet C, Pedersen J, Gauthier F, Jenne DE, Marchand-Adam S, Chapple IL, Kettritz R, Korkmaz B.

J Biol Chem. 2018 Aug 10;293(32):12415-12428. doi: 10.1074/jbc.RA118.001922. Epub 2018 Jun 20.

10.

Therapeutic targeting of cathepsin C: from pathophysiology to treatment.

Korkmaz B, Caughey GH, Chapple I, Gauthier F, Hirschfeld J, Jenne DE, Kettritz R, Lalmanach G, Lamort AS, Lauritzen C, Łȩgowska M, Lesner A, Marchand-Adam S, McKaig SJ, Moss C, Pedersen J, Roberts H, Schreiber A, Seren S, Thakker NS.

Pharmacol Ther. 2018 Oct;190:202-236. doi: 10.1016/j.pharmthera.2018.05.011. Epub 2018 May 26. Review.

PMID:
29842917
11.

Preservation with α1-antitrypsin improves primary graft function of murine lung transplants.

Götzfried J, Smirnova NF, Morrone C, Korkmaz B, Yildirim AÖ, Eickelberg O, Jenne DE.

J Heart Lung Transplant. 2018 Aug;37(8):1021-1028. doi: 10.1016/j.healun.2018.03.015. Epub 2018 Mar 30.

12.

Exploiting the S4-S5 Specificity of Human Neutrophil Proteinase 3 to Improve the Potency of Peptidyl Di(chlorophenyl)-phosphonate Ester Inhibitors: A Kinetic and Molecular Modeling Analysis.

Guarino C, Gruba N, Grzywa R, Dyguda-Kazimierowicz E, Hamon Y, Łȩgowska M, Skoreński M, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Jenne DE, Sieńczyk M, Lesner A, Gauthier F, Korkmaz B.

J Med Chem. 2018 Mar 8;61(5):1858-1870. doi: 10.1021/acs.jmedchem.7b01416. Epub 2018 Feb 26.

PMID:
29442501
13.

Optimal duration of adjuvant endocrine therapy: how to apply the newest data.

Wimmer K, Strobl S, Bolliger M, Devyatko Y, Korkmaz B, Exner R, Fitzal F, Gnant M.

Ther Adv Med Oncol. 2017 Nov;9(11):679-692. doi: 10.1177/1758834017732966. Epub 2017 Oct 27. Review.

14.

Substrate-derived triazolo- and azapeptides as inhibitors of cathepsins K and S.

Galibert M, Wartenberg M, Lecaille F, Saidi A, Mavel S, Joulin-Giet A, Korkmaz B, Brömme D, Aucagne V, Delmas AF, Lalmanach G.

Eur J Med Chem. 2018 Jan 20;144:201-210. doi: 10.1016/j.ejmech.2017.12.012. Epub 2017 Dec 7.

PMID:
29272750
15.

Image-based ex-vivo drug screening for patients with aggressive haematological malignancies: interim results from a single-arm, open-label, pilot study.

Snijder B, Vladimer GI, Krall N, Miura K, Schmolke AS, Kornauth C, Lopez de la Fuente O, Choi HS, van der Kouwe E, Gültekin S, Kazianka L, Bigenzahn JW, Hoermann G, Prutsch N, Merkel O, Ringler A, Sabler M, Jeryczynski G, Mayerhoefer ME, Simonitsch-Klupp I, Ocko K, Felberbauer F, Müllauer L, Prager GW, Korkmaz B, Kenner L, Sperr WR, Kralovics R, Gisslinger H, Valent P, Kubicek S, Jäger U, Staber PB, Superti-Furga G.

Lancet Haematol. 2017 Dec;4(12):e595-e606. doi: 10.1016/S2352-3026(17)30208-9. Epub 2017 Nov 15.

16.

The role of Syk/IĸB-α/NF-ĸB pathway activation in the reversal effect of BAY 61-3606, a selective Syk inhibitor, on hypotension and inflammation in a rat model of zymosan-induced non-septic shock.

Unsal D, Kacan M, Temiz-Resitoglu M, Guden DS, Korkmaz B, Sari AN, Buharalioglu CK, Yildirim-Yaroglu H, Tamer-Gumus L, Tunctan B, Malik KU, Sahan-Firat S.

Clin Exp Pharmacol Physiol. 2018 Feb;45(2):155-165. doi: 10.1111/1440-1681.12864. Epub 2017 Nov 28.

PMID:
28949404
17.

Adolescent pregnancies: complications, birth outcomes and the possible solutions.

Çift T, Korkmazer E, Temur M, Bulut B, Korkmaz B, Ozdenoğlu O, Akaltun C, Üstünyurt E.

Ginekol Pol. 2017;88(7):393-397. doi: 10.5603/GP.a2017.0073.

18.

Evaluation of in vivo analgesic activity of Scrophularia kotscyhana and isolation of bioactive compounds through activity-guided fractionation.

Renda G, Korkmaz B, Kılıç M, Duman MK, Kırmızıbekmez H.

Nat Prod Res. 2018 Aug;32(16):1902-1910. doi: 10.1080/14786419.2017.1356829. Epub 2017 Jul 31.

PMID:
28758426
19.

EEG abnormalities and long term seizure outcome in high functioning autism.

Ertürk Çetin Ö, Korkmaz B, Alev G, Demirbilek V.

Acta Neurol Belg. 2017 Sep;117(3):729-732. doi: 10.1007/s13760-017-0785-8. Epub 2017 Apr 26.

PMID:
28447214
20.

Prolonged pharmacological inhibition of cathepsin C results in elimination of neutrophil serine proteases.

Guarino C, Hamon Y, Croix C, Lamort AS, Dallet-Choisy S, Marchand-Adam S, Lesner A, Baranek T, Viaud-Massuard MC, Lauritzen C, Pedersen J, Heuzé-Vourc'h N, Si-Tahar M, Fıratlı E, Jenne DE, Gauthier F, Horwitz MS, Borregaard N, Korkmaz B.

Biochem Pharmacol. 2017 May 1;131:52-67. doi: 10.1016/j.bcp.2017.02.009. Epub 2017 Feb 11.

PMID:
28193451
21.

Demonstration of sympathetic dysfunction in patients with obstructive sleep apnea syndrome by measuring sympathetic skin responses from the neck.

Korkmaz B, Benbir Şenel G, Kızıltan ME, Karadeniz D.

Sleep Med. 2016 Sep;25:13-15. doi: 10.1016/j.sleep.2016.06.030. Epub 2016 Sep 1.

PMID:
27823705
22.

Pseudomonas aeruginosa proteolytically alters the interleukin 22-dependent lung mucosal defense.

Guillon A, Brea D, Morello E, Tang A, Jouan Y, Ramphal R, Korkmaz B, Perez-Cruz M, Trottein F, O'Callaghan RJ, Gosset P, Si-Tahar M.

Virulence. 2017 Aug 18;8(6):810-820. doi: 10.1080/21505594.2016.1253658. Epub 2016 Oct 28.

23.

Development of the first internally-quenched fluorescent substrates of human cathepsin C: The application in the enzyme detection in biological samples.

Łęgowska M, Hamon Y, Wojtysiak A, Grzywa R, Sieńczyk M, Burster T, Korkmaz B, Lesner A.

Arch Biochem Biophys. 2016 Dec 15;612:91-102. doi: 10.1016/j.abb.2016.10.007. Epub 2016 Oct 13.

PMID:
27746119
24.

Evaluation of the Tibial Nerve with Shear-Wave Elastography: A Potential Sonographic Method for the Diagnosis of Diabetic Peripheral Neuropathy.

Dikici AS, Ustabasioglu FE, Delil S, Nalbantoglu M, Korkmaz B, Bakan S, Kula O, Uzun N, Mihmanli I, Kantarci F.

Radiology. 2017 Feb;282(2):494-501. doi: 10.1148/radiol.2016160135. Epub 2016 Sep 19.

PMID:
27643671
25.

Neutrophils can disarm NK cell response through cleavage of NKp46.

Valayer A, Brea D, Lajoie L, Avezard L, Combes-Soia L, Labas V, Korkmaz B, Thibault G, Baranek T, Si-Tahar M.

J Leukoc Biol. 2017 Jan;101(1):253-259. doi: 10.1189/jlb.3AB0316-140RR. Epub 2016 Sep 1.

PMID:
27587403
26.

Inhibitors and Antibody Fragments as Potential Anti-Inflammatory Therapeutics Targeting Neutrophil Proteinase 3 in Human Disease.

Korkmaz B, Lesner A, Guarino C, Wysocka M, Kellenberger C, Watier H, Specks U, Gauthier F, Jenne DE.

Pharmacol Rev. 2016 Jul;68(3):603-30. doi: 10.1124/pr.115.012104. Review.

PMID:
27329045
27.

Startle and blink reflex in high functioning autism.

Erturk O, Korkmaz B, Alev G, Demirbilek V, Kiziltan M.

Neurophysiol Clin. 2016 Jun;46(3):189-92. doi: 10.1016/j.neucli.2016.02.001. Epub 2016 Mar 17.

PMID:
26997128
28.

Neutrophilic Cathepsin C Is Maturated by a Multistep Proteolytic Process and Secreted by Activated Cells during Inflammatory Lung Diseases.

Hamon Y, Legowska M, Hervé V, Dallet-Choisy S, Marchand-Adam S, Vanderlynden L, Demonte M, Williams R, Scott CJ, Si-Tahar M, Heuzé-Vourc'h N, Lalmanach G, Jenne DE, Lesner A, Gauthier F, Korkmaz B.

J Biol Chem. 2016 Apr 15;291(16):8486-99. doi: 10.1074/jbc.M115.707109. Epub 2016 Feb 16.

29.

Analysis of urinary cathepsin C for diagnosing Papillon-Lefèvre syndrome.

Hamon Y, Legowska M, Fergelot P, Dallet-Choisy S, Newell L, Vanderlynden L, Kord Valeshabad A, Acrich K, Kord H, Charalampos T, Morice-Picard F, Surplice I, Zoidakis J, David K, Vlahou A, Ragunatha S, Nagy N, Farkas K, Széll M, Goizet C, Schacher B, Battino M, Al Farraj Aldosari A, Wang X, Liu Y, Marchand-Adam S, Lesner A, Kara E, Korkmaz-Icöz S, Moss C, Eickholz P, Taieb A, Kavukcu S, Jenne DE, Gauthier F, Korkmaz B.

FEBS J. 2016 Feb;283(3):498-509. doi: 10.1111/febs.13605. Epub 2016 Jan 4.

30.

Adjuvant Bisphosphonates and Breast Cancer Survival.

Strobl S, Korkmaz B, Devyatko Y, Schuetz M, Exner R, Dubsky PC, Jakesz R, Gnant M.

Annu Rev Med. 2016;67:1-10. doi: 10.1146/annurev-med-053014-103600. Epub 2015 Aug 28. Review.

PMID:
26332000
31.

Neutrophil serine proteases exert proteolytic activity on endothelial cells.

Jerke U, Hernandez DP, Beaudette P, Korkmaz B, Dittmar G, Kettritz R.

Kidney Int. 2015 Oct;88(4):764-75. doi: 10.1038/ki.2015.159. Epub 2015 Jun 10.

PMID:
26061547
32.

Sympathetic Skin Responses from the Neck Area in Patients with Unilateral Migraine.

Korkmaz B, Yildiz S, Yildiz N.

Noro Psikiyatr Ars. 2015 Jun;52(2):151-156. doi: 10.5152/npa.2015.7601. Epub 2015 Jun 1.

33.

Features of the traffic accidents happened in the province of Aydın between 2005 and 2011.

Dirlik M, Bostancıoğlu BÇ, Elbek T, Korkmaz B, Çallak Kallem F, Gün B.

Ulus Travma Acil Cerrahi Derg. 2014 Sep;20(5):353-8. doi: 10.5505/tjtes.2014.18828.

34.

First-trimester crown-rump length affects birth size symmetrically.

Ustunyurt E, Simsek H, Korkmaz B, Iskender C.

J Matern Fetal Neonatal Med. 2015;28(17):2070-3. doi: 10.3109/14767058.2014.978278. Epub 2014 Nov 11.

PMID:
25327173
35.

New selective peptidyl di(chlorophenyl) phosphonate esters for visualizing and blocking neutrophil proteinase 3 in human diseases.

Guarino C, Legowska M, Epinette C, Kellenberger C, Dallet-Choisy S, Sieńczyk M, Gabant G, Cadene M, Zoidakis J, Vlahou A, Wysocka M, Marchand-Adam S, Jenne DE, Lesner A, Gauthier F, Korkmaz B.

J Biol Chem. 2014 Nov 14;289(46):31777-91. doi: 10.1074/jbc.M114.591339. Epub 2014 Oct 6.

36.

Effective treatment of congenital muscular torticollis using botulinum toxin.

Gündüz A, Korkmaz B, Kiziltan ME.

J Craniofac Surg. 2014 Sep;25(5):1935. doi: 10.1097/SCS.0000000000001123. No abstract available.

PMID:
25119409
37.

Effects of 5,14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in a rat model of septic shock.

Sari AN, Korkmaz B, Serin MS, Kacan M, Unsal D, Buharalioglu CK, Sahan Firat S, Manthati VL, Falck JR, Malik KU, Tunctan B.

Inflamm Res. 2014 Sep;63(9):741-56. doi: 10.1007/s00011-014-0747-z. Epub 2014 Jun 12.

38.

Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ injury in rats.

Sari AN, Kacan M, Unsal D, Sahan Firat S, Kemal Buharalioglu C, Vezir O, Korkmaz B, Cuez T, Canacankatan N, Sucu N, Ayaz L, Tamer Gumus L, Gorur A, Tunctan B.

Eur J Pharmacol. 2014 Jan 15;723:234-45. doi: 10.1016/j.ejphar.2013.11.027. Epub 2013 Dec 1.

PMID:
24296316
39.

Angiogenesis stimulated by human kallikrein-related peptidase 12 acting via a platelet-derived growth factor B-dependent paracrine pathway.

Kryza T, Achard C, Parent C, Marchand-Adam S, Guillon-Munos A, Iochmann S, Korkmaz B, Respaud R, Courty Y, Heuzé-Vourc'h N.

FASEB J. 2014 Feb;28(2):740-51. doi: 10.1096/fj.13-237503. Epub 2013 Nov 13.

PMID:
24225148
40.

Decreased head circumference in shunt-treated compared with healthy children.

Nilsson D, Svensson J, Korkmaz BA, Nelvig H, Tisell M.

J Neurosurg Pediatr. 2013 Nov;12(5):483-90. doi: 10.3171/2013.8.PEDS1370. Epub 2013 Sep 13.

PMID:
24032988
41.

A new proteinase 3 substrate with improved selectivity over human neutrophil elastase.

Popow-Stellmaszyk J, Wysocka M, Lesner A, Korkmaz B, Rolka K.

Anal Biochem. 2013 Nov 1;442(1):75-82. doi: 10.1016/j.ab.2013.07.028. Epub 2013 Jul 30.

PMID:
23911525
42.

A monoclonal antibody (MCPR3-7) interfering with the activity of proteinase 3 by an allosteric mechanism.

Hinkofer LC, Seidel SA, Korkmaz B, Silva F, Hummel AM, Braun D, Jenne DE, Specks U.

J Biol Chem. 2013 Sep 13;288(37):26635-48. doi: 10.1074/jbc.M113.495770. Epub 2013 Jul 31.

43.

Relevance of the mouse model as a therapeutic approach for neutrophil proteinase 3-associated human diseases.

Korkmaz B, Jenne DE, Gauthier F.

Int Immunopharmacol. 2013 Dec;17(4):1198-205. doi: 10.1016/j.intimp.2013.07.003. Epub 2013 Jul 23. Review.

PMID:
23886601
44.

Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91(phox) to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Manthati VL, Falck JR, Malik KU.

Nitric Oxide. 2013 Sep 1;33:18-41. doi: 10.1016/j.niox.2013.05.001. Epub 2013 May 14.

45.

5,14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2/IKKβ/IκB-α/NF-κB pathway, and proinflammatory cytokine formation.

Tunctan B, Korkmaz B, Sari AN, Kacan M, Unsal D, Serin MS, Buharalioglu CK, Sahan-Firat S, Cuez T, Schunck WH, Falck JR, Malik KU.

Prostaglandins Other Lipid Mediat. 2013 Apr-May;102-103:31-41. doi: 10.1016/j.prostaglandins.2013.01.005. Epub 2013 Feb 27.

46.

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).

Korkmaz B, Lesner A, Letast S, Mahdi YK, Jourdan ML, Dallet-Choisy S, Marchand-Adam S, Kellenberger C, Viaud-Massuard MC, Jenne DE, Gauthier F.

Semin Immunopathol. 2013 Jul;35(4):411-21. doi: 10.1007/s00281-013-0362-z. Epub 2013 Feb 6. Review.

PMID:
23385856
47.

Contribution of MEK1/ERK1/2/iNOS pathway to oxidative stress and decreased caspase-3 activity in endotoxemic rats.

Korkmaz B, Cuez T, Buharalioglu CK, Demiryurek AT, Sahan-Firat S, Sari AN, Tunctan B.

Antiinflamm Antiallergy Agents Med Chem. 2012;11(3):243-52.

PMID:
23189948
48.

Increased production of nitric oxide mediates selective organ-specific effects of endotoxin on oxidative stress.

Sahan-Firat S, Canacankatan N, Korkmaz B, Yildirim H, Tamer L, Buharalioglu CK, Sari AN, Kacan M, Unsal D, Tunctan B.

Antiinflamm Antiallergy Agents Med Chem. 2012;11(2):161-72.

PMID:
23173576
49.

Crystal structure of greglin, a novel non-classical Kazal inhibitor, in complex with subtilisin.

Derache C, Epinette C, Roussel A, Gabant G, Cadene M, Korkmaz B, Gauthier F, Kellenberger C.

FEBS J. 2012 Dec;279(24):4466-78. doi: 10.1111/febs.12033. Epub 2012 Nov 12.

50.

Selective inhibitors of human neutrophil proteinase 3.

Korkmaz B, Kellenberger C, Viaud-Massuard MC, Gauthier F.

Curr Pharm Des. 2013;19(6):966-76. Review.

PMID:
23016687

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