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Items: 1 to 50 of 55

1.

Comparative genome analysis indicates high evolutionary potential of pathogenicity genes in Colletotrichum tanaceti.

Lelwala RV, Korhonen PK, Young ND, Scott JB, Ades PK, Gasser RB, Taylor PWJ.

PLoS One. 2019 May 31;14(5):e0212248. doi: 10.1371/journal.pone.0212248. eCollection 2019.

2.

Long-read sequencing reveals a 4.4 kb tandem repeat region in the mitogenome of Echinococcus granulosus (sensu stricto) genotype G1.

Kinkar L, Korhonen PK, Cai H, Gauci CG, Lightowlers MW, Saarma U, Jenkins DJ, Li J, Li J, Young ND, Gasser RB.

Parasit Vectors. 2019 May 16;12(1):238. doi: 10.1186/s13071-019-3492-x.

3.

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus.

Wang T, Ma G, Ang CS, Korhonen PK, Koehler AV, Young ND, Nie S, Williamson NA, Gasser RB.

J Proteomics. 2019 Jul 30;204:103375. doi: 10.1016/j.jprot.2019.05.003. Epub 2019 May 6.

PMID:
31071474
4.

Dauer signalling pathway model for Haemonchus contortus.

Ma G, Wang T, Korhonen PK, Stroehlein AJ, Young ND, Gasser RB.

Parasit Vectors. 2019 Apr 29;12(1):187. doi: 10.1186/s13071-019-3419-6.

5.

Common workflow language (CWL)-based software pipeline for de novo genome assembly from long- and short-read data.

Korhonen PK, Hall RS, Young ND, Gasser RB.

Gigascience. 2019 Apr 1;8(4). pii: giz014. doi: 10.1093/gigascience/giz014.

6.

Somatic proteome of Haemonchus contortus.

Wang T, Ma G, Ang CS, Korhonen PK, Xu R, Nie S, Koehler AV, Simpson RJ, Greening DW, Reid GE, Williamson NA, Gasser RB.

Int J Parasitol. 2019 Mar;49(3-4):311-320. doi: 10.1016/j.ijpara.2018.12.003. Epub 2019 Feb 14.

PMID:
30771357
7.

Molecular evidence for distinct modes of nutrient acquisition between visceral and neurotropic schistosomes of birds.

Leontovyč R, Young ND, Korhonen PK, Hall RS, Bulantová J, Jeřábková V, Kašný M, Gasser RB, Horák P.

Sci Rep. 2019 Feb 4;9(1):1347. doi: 10.1038/s41598-018-37669-2.

8.

Whole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium.

Oey H, Zakrzewski M, Gravermann K, Young ND, Korhonen PK, Gobert GN, Nawaratna S, Hasan S, Martínez DM, You H, Lavin M, Jones MK, Ragan MA, Stoye J, Oleaga A, Emery AM, Webster BL, Rollinson D, Gasser RB, McManus DP, Krause L.

PLoS Pathog. 2019 Jan 23;15(1):e1007513. doi: 10.1371/journal.ppat.1007513. eCollection 2019 Jan.

9.

Comparative bioinformatic analysis suggests that specific dauer-like signalling pathway components regulate Toxocara canis development and migration in the mammalian host.

Ma G, Wang T, Korhonen PK, Nie S, Reid GE, Stroehlein AJ, Koehler AV, Chang BCH, Hofmann A, Young ND, Gasser RB.

Parasit Vectors. 2019 Jan 14;12(1):32. doi: 10.1186/s13071-018-3265-y.

10.

A TGF-β type I receptor-like molecule with a key functional role in Haemonchus contortus development.

He L, Gasser RB, Korhonen PK, Di W, Li F, Zhang H, Li F, Zhou Y, Fang R, Zhao J, Hu M.

Int J Parasitol. 2018 Nov;48(13):1023-1033. doi: 10.1016/j.ijpara.2018.06.005. Epub 2018 Sep 26.

PMID:
30266591
11.

The developmental lipidome of Haemonchus contortus.

Wang T, Nie S, Ma G, Korhonen PK, Koehler AV, Ang CS, Reid GE, Williamson NA, Gasser RB.

Int J Parasitol. 2018 Oct;48(12):887-895. doi: 10.1016/j.ijpara.2018.06.002. Epub 2018 Sep 1.

PMID:
30176232
12.

Best practice data life cycle approaches for the life sciences.

Griffin PC, Khadake J, LeMay KS, Lewis SE, Orchard S, Pask A, Pope B, Roessner U, Russell K, Seemann T, Treloar A, Tyagi S, Christiansen JH, Dayalan S, Gladman S, Hangartner SB, Hayden HL, Ho WWH, Keeble-Gagnère G, Korhonen PK, Neish P, Prestes PR, Richardson MF, Watson-Haigh NS, Wyres KL, Young ND, Schneider MV.

Version 2. F1000Res. 2017 Aug 31 [revised 2018 Jan 1];6:1618. doi: 10.12688/f1000research.12344.2. eCollection 2017.

13.

The small RNA complement of adult Schistosoma haematobium.

Stroehlein AJ, Young ND, Korhonen PK, Hall RS, Jex AR, Webster BL, Rollinson D, Brindley PJ, Gasser RB.

PLoS Negl Trop Dis. 2018 May 29;12(5):e0006535. doi: 10.1371/journal.pntd.0006535. eCollection 2018 May.

14.

Molecular alterations during larval development of Haemonchus contortus in vitro are under tight post-transcriptional control.

Ma G, Wang T, Korhonen PK, Ang CS, Williamson NA, Young ND, Stroehlein AJ, Hall RS, Koehler AV, Hofmann A, Gasser RB.

Int J Parasitol. 2018 Aug;48(9-10):763-772. doi: 10.1016/j.ijpara.2018.03.008. Epub 2018 May 22.

PMID:
29792880
15.

Clonorchis sinensis and Clonorchiasis: The Relevance of Exploring Genetic Variation.

Wang D, Young ND, Korhonen PK, Gasser RB.

Adv Parasitol. 2018;100:155-208. doi: 10.1016/bs.apar.2018.03.006. Epub 2018 May 4. Review.

PMID:
29753338
16.

Improved genomic resources and new bioinformatic workflow for the carcinogenic parasite Clonorchis sinensis: Biotechnological implications.

Wang D, Korhonen PK, Gasser RB, Young ND.

Biotechnol Adv. 2018 Jul - Aug;36(4):894-904. doi: 10.1016/j.biotechadv.2018.02.008. Epub 2018 Feb 15. Review.

PMID:
29454982
17.

Use of a bioinformatic-assisted primer design strategy to establish a new nested PCR-based method for Cryptosporidium.

Koehler AV, Korhonen PK, Hall RS, Young ND, Wang T, Haydon SR, Gasser RB.

Parasit Vectors. 2017 Oct 23;10(1):509. doi: 10.1186/s13071-017-2462-4.

18.

The Battle Against Flystrike - Past Research and New Prospects Through Genomics.

Anstead CA, Perry T, Richards S, Korhonen PK, Young ND, Bowles VM, Batterham P, Gasser RB.

Adv Parasitol. 2017;98:227-281. doi: 10.1016/bs.apar.2017.03.001. Epub 2017 May 5.

PMID:
28942770
19.

Deguelin exerts potent nematocidal activity via the mitochondrial respiratory chain.

Preston S, Korhonen PK, Mouchiroud L, Cornaglia M, McGee SL, Young ND, Davis RA, Crawford S, Nowell C, Ansell BRE, Fisher GM, Andrews KT, Chang BCH, Gijs MAM, Sternberg PW, Auwerx J, Baell J, Hofmann A, Jabbar A, Gasser RB.

FASEB J. 2017 Oct;31(10):4515-4532. doi: 10.1096/fj.201700288R. Epub 2017 Jul 7.

PMID:
28687609
20.

Whipworm kinomes reflect a unique biology and adaptation to the host animal.

Stroehlein AJ, Young ND, Korhonen PK, Chang BCH, Nejsum P, Pozio E, La Rosa G, Sternberg PW, Gasser RB.

Int J Parasitol. 2017 Nov;47(13):857-866. doi: 10.1016/j.ijpara.2017.04.005. Epub 2017 Jun 10.

PMID:
28606697
21.

Mitochondrial genomic comparison of Clonorchis sinensis from South Korea with other isolates of this species.

Wang D, Young ND, Koehler AV, Tan P, Sohn WM, Korhonen PK, Gasser RB.

Infect Genet Evol. 2017 Jul;51:160-166. doi: 10.1016/j.meegid.2017.02.015. Epub 2017 Feb 22.

PMID:
28254628
22.

The apicoplast genomes of two taxonomic units of Babesia from sheep.

Wang T, Guan G, Korhonen PK, Koehler AV, Hall RS, Young ND, Yin H, Gasser RB.

Vet Parasitol. 2017 Jan 15;233:123-128. doi: 10.1016/j.vetpar.2016.11.004. Epub 2016 Nov 6.

PMID:
27916258
23.

Mitochondrial genomes of two Babesia taxa from sheep in China as a foundation for population genetic and epidemiological investigations.

Wang T, Guan G, Korhonen PK, Koehler AV, Young ND, Hall RS, Yin H, Gasser RB.

Infect Genet Evol. 2017 Jan;47:51-55. doi: 10.1016/j.meegid.2016.11.002. Epub 2016 Nov 11.

PMID:
27845269
24.

Comparative transcriptomic analyses of male and female adult Toxocara canis.

Zhou RQ, Ma GX, Korhonen PK, Luo YL, Zhu HH, Luo YF, Gasser RB, Xia QY.

Gene. 2017 Feb 5;600:85-89. doi: 10.1016/j.gene.2016.11.024. Epub 2016 Nov 12.

PMID:
27845205
25.

Genomic resources for a unique, low-virulence Babesia taxon from China.

Guan G, Korhonen PK, Young ND, Koehler AV, Wang T, Li Y, Liu Z, Luo J, Yin H, Gasser RB.

Parasit Vectors. 2016 Oct 27;9(1):564.

26.

Divergent Transcriptional Responses to Physiological and Xenobiotic Stress in Giardia duodenalis.

Ansell BR, McConville MJ, Baker L, Korhonen PK, Emery SJ, Svärd SG, Gasser RB, Jex AR.

Antimicrob Agents Chemother. 2016 Sep 23;60(10):6034-45. doi: 10.1128/AAC.00977-16. Print 2016 Oct.

27.

Analyses of Compact Trichinella Kinomes Reveal a MOS-Like Protein Kinase with a Unique N-Terminal Domain.

Stroehlein AJ, Young ND, Korhonen PK, Chang BC, Sternberg PW, La Rosa G, Pozio E, Gasser RB.

G3 (Bethesda). 2016 Sep 8;6(9):2847-56. doi: 10.1534/g3.116.032961.

28.

CAP protein superfamily members in Toxocara canis.

Stroehlein AJ, Young ND, Hall RS, Korhonen PK, Hofmann A, Sternberg PW, Jabbar A, Gasser RB.

Parasit Vectors. 2016 Jun 24;9(1):360. doi: 10.1186/s13071-016-1642-y.

29.

Understanding Haemonchus contortus Better Through Genomics and Transcriptomics.

Gasser RB, Schwarz EM, Korhonen PK, Young ND.

Adv Parasitol. 2016;93:519-67. doi: 10.1016/bs.apar.2016.02.015. Epub 2016 Apr 5. Review.

PMID:
27238012
30.

MicroRNAs of Toxocara canis and their predicted functional roles.

Ma G, Luo Y, Zhu H, Luo Y, Korhonen PK, Young ND, Gasser RB, Zhou R.

Parasit Vectors. 2016 Apr 23;9:229. doi: 10.1186/s13071-016-1508-3.

31.

Harnessing the Toxocara Genome to Underpin Toxocariasis Research and New Interventions.

Gasser RB, Korhonen PK, Zhu XQ, Young ND.

Adv Parasitol. 2016;91:87-110. doi: 10.1016/bs.apar.2015.12.001. Epub 2016 Feb 28. Review.

PMID:
27015948
32.

Pipeline for the identification and classification of ion channels in parasitic flatworms.

Nor B, Young ND, Korhonen PK, Hall RS, Tan P, Lonie A, Gasser RB.

Parasit Vectors. 2016 Mar 16;9:155. doi: 10.1186/s13071-016-1428-2.

33.

Making sense of genomes of parasitic worms: Tackling bioinformatic challenges.

Korhonen PK, Young ND, Gasser RB.

Biotechnol Adv. 2016 Sep-Oct;34(5):663-686. doi: 10.1016/j.biotechadv.2016.03.001. Epub 2016 Mar 5. Review.

PMID:
26956711
34.

A blow to the fly - Lucilia cuprina draft genome and transcriptome to support advances in biology and biotechnology.

Anstead CA, Batterham P, Korhonen PK, Young ND, Hall RS, Bowles VM, Richards S, Scott MJ, Gasser RB.

Biotechnol Adv. 2016 Sep-Oct;34(5):605-620. doi: 10.1016/j.biotechadv.2016.02.009. Epub 2016 Mar 2. Review.

PMID:
26944522
35.

Comparative Transcriptomic Exploration Reveals Unique Molecular Adaptations of Neuropathogenic Trichobilharzia to Invade and Parasitize Its Avian Definitive Host.

Leontovyč R, Young ND, Korhonen PK, Hall RS, Tan P, Mikeš L, Kašný M, Horák P, Gasser RB.

PLoS Negl Trop Dis. 2016 Feb 10;10(2):e0004406. doi: 10.1371/journal.pntd.0004406. eCollection 2016 Feb.

36.

Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1).

Li FC, Gasser RB, Lok JB, Korhonen PK, He L, Di WD, Yin FY, Zhou R, Zhou YQ, Zhao JL, Hu M.

Parasit Vectors. 2016 Feb 3;9:65. doi: 10.1186/s13071-016-1351-6.

37.

Phylogenomic and biogeographic reconstruction of the Trichinella complex.

Korhonen PK, Pozio E, La Rosa G, Chang BC, Koehler AV, Hoberg EP, Boag PR, Tan P, Jex AR, Hofmann A, Sternberg PW, Young ND, Gasser RB.

Nat Commun. 2016 Feb 1;7:10513. doi: 10.1038/ncomms10513.

38.

The Haemonchus contortus kinome--a resource for fundamental molecular investigations and drug discovery.

Stroehlein AJ, Young ND, Korhonen PK, Jabbar A, Hofmann A, Sternberg PW, Gasser RB.

Parasit Vectors. 2015 Dec 8;8:623. doi: 10.1186/s13071-015-1231-5.

39.

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites.

Ansell BR, McConville MJ, Baker L, Korhonen PK, Young ND, Hall RS, Rojas CA, Svärd SG, Gasser RB, Jex AR.

PLoS Negl Trop Dis. 2015 Dec 4;9(12):e0004261. doi: 10.1371/journal.pntd.0004261. eCollection 2015 Dec.

40.

Exploring molecular variation in Schistosoma japonicum in China.

Young ND, Chan KG, Korhonen PK, Min Chong T, Ee R, Mohandas N, Koehler AV, Lim YL, Hofmann A, Jex AR, Qian B, Chilton NB, Gobert GN, McManus DP, Tan P, Webster BL, Rollinson D, Gasser RB.

Sci Rep. 2015 Dec 1;5:17345. doi: 10.1038/srep17345.

41.

The complement of family M1 aminopeptidases of Haemonchus contortus--Biotechnological implications.

Mohandas N, Young ND, Jabbar A, Korhonen PK, Koehler AV, Hall RS, Hu M, Hofmann A, Gasser RB.

Biotechnol Adv. 2016 Mar-Apr;34(2):65-76. doi: 10.1016/j.biotechadv.2015.10.003. Epub 2015 Oct 24. Review.

PMID:
26597954
42.

The barber's pole worm CAP protein superfamily--A basis for fundamental discovery and biotechnology advances.

Mohandas N, Young ND, Jabbar A, Korhonen PK, Koehler AV, Amani P, Hall RS, Sternberg PW, Jex AR, Hofmann A, Gasser RB.

Biotechnol Adv. 2015 Dec;33(8):1744-54. doi: 10.1016/j.biotechadv.2015.07.003. Epub 2015 Jul 31. Review.

PMID:
26239368
43.

Lucilia cuprina genome unlocks parasitic fly biology to underpin future interventions.

Anstead CA, Korhonen PK, Young ND, Hall RS, Jex AR, Murali SC, Hughes DS, Lee SF, Perry T, Stroehlein AJ, Ansell BR, Breugelmans B, Hofmann A, Qu J, Dugan S, Lee SL, Chao H, Dinh H, Han Y, Doddapaneni HV, Worley KC, Muzny DM, Ioannidis P, Waterhouse RM, Zdobnov EM, James PJ, Bagnall NH, Kotze AC, Gibbs RA, Richards S, Batterham P, Gasser RB.

Nat Commun. 2015 Jun 25;6:7344. doi: 10.1038/ncomms8344.

44.

Low cost whole-organism screening of compounds for anthelmintic activity.

Preston S, Jabbar A, Nowell C, Joachim A, Ruttkowski B, Baell J, Cardno T, Korhonen PK, Piedrafita D, Ansell BR, Jex AR, Hofmann A, Gasser RB.

Int J Parasitol. 2015 Apr;45(5):333-43. doi: 10.1016/j.ijpara.2015.01.007. Epub 2015 Mar 5.

PMID:
25746136
45.

Genetic blueprint of the zoonotic pathogen Toxocara canis.

Zhu XQ, Korhonen PK, Cai H, Young ND, Nejsum P, von Samson-Himmelstjerna G, Boag PR, Tan P, Li Q, Min J, Yang Y, Wang X, Fang X, Hall RS, Hofmann A, Sternberg PW, Jex AR, Gasser RB.

Nat Commun. 2015 Feb 4;6:6145. doi: 10.1038/ncomms7145.

46.

Exploring the role of two interacting phosphoinositide 3-kinases of Haemonchus contortus.

Li FC, Gasser RB, Lok JB, Korhonen PK, Wang YF, Yin FY, He L, Zhou R, Zhao JL, Hu M.

Parasit Vectors. 2014 Nov 12;7:498. doi: 10.1186/s13071-014-0498-2.

47.

Mitochondrial genomes of Trichinella species and genotypes – a basis for diagnosis, and systematic and epidemiological explorations.

Mohandas N, Pozio E, La Rosa G, Korhonen PK, Young ND, Koehler AV, Hall RS, Sternberg PW, Boag PR, Jex AR, Chang BC, Gasser RB.

Int J Parasitol. 2014 Dec;44(14):1073-80. doi: 10.1016/j.ijpara.2014.08.010.

PMID:
25245252
48.

Bioinformatic exploration of RIO protein kinases of parasitic and free-living nematodes.

Breugelmans B, Jex AR, Korhonen PK, Mangiola S, Young ND, Sternberg PW, Boag PR, Hofmann A, Gasser RB.

Int J Parasitol. 2014 Oct 1;44(11):827-36. doi: 10.1016/j.ijpara.2014.06.005. Epub 2014 Jul 17.

PMID:
25038443
49.

The Opisthorchis viverrini genome provides insights into life in the bile duct.

Young ND, Nagarajan N, Lin SJ, Korhonen PK, Jex AR, Hall RS, Safavi-Hemami H, Kaewkong W, Bertrand D, Gao S, Seet Q, Wongkham S, Teh BT, Wongkham C, Intapan PM, Maleewong W, Yang X, Hu M, Wang Z, Hofmann A, Sternberg PW, Tan P, Wang J, Gasser RB.

Nat Commun. 2014 Jul 9;5:4378. doi: 10.1038/ncomms5378.

50.

Genome and transcriptome of the porcine whipworm Trichuris suis.

Jex AR, Nejsum P, Schwarz EM, Hu L, Young ND, Hall RS, Korhonen PK, Liao S, Thamsborg S, Xia J, Xu P, Wang S, Scheerlinck JP, Hofmann A, Sternberg PW, Wang J, Gasser RB.

Nat Genet. 2014 Jul;46(7):701-6. doi: 10.1038/ng.3012. Epub 2014 Jun 15.

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