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Items: 1 to 50 of 306

1.

Disease Modification Through Trophic Factor Delivery.

Savolainen M, Emerich D, Kordower JH.

Methods Mol Biol. 2018;1780:525-547. doi: 10.1007/978-1-4939-7825-0_24.

PMID:
29856034
2.

Disease Modification for Parkinson's Disease: Axonal Regeneration and Trophic Factors.

Kordower JH, Burke RE.

Mov Disord. 2018 May;33(5):678-683. doi: 10.1002/mds.27383. Epub 2018 Mar 30. Review.

PMID:
29603370
3.

Analysis of age-related changes in psychosine metabolism in the human brain.

Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER.

PLoS One. 2018 Feb 26;13(2):e0193438. doi: 10.1371/journal.pone.0193438. eCollection 2018.

4.

Do subjects with minimal motor features have prodromal Parkinson disease?

Chu Y, Buchman AS, Olanow CW, Kordower JH.

Ann Neurol. 2018 Mar;83(3):562-574. doi: 10.1002/ana.25179. Epub 2018 Mar 10.

PMID:
29420861
5.

Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease.

Pal G, Ouyang B, Verhagen L, Serrano G, Shill HA, Adler CH, Beach TG, Kordower JH; AZSAND.

Mov Disord. 2018 Apr;33(4):652-654. doi: 10.1002/mds.27280. Epub 2018 Jan 30. No abstract available.

PMID:
29380902
6.

Induction of alpha-synuclein pathology in the enteric nervous system of the rat and non-human primate results in gastrointestinal dysmotility and transient CNS pathology.

Manfredsson FP, Luk KC, Benskey MJ, Gezer A, Garcia J, Kuhn NC, Sandoval IM, Patterson JR, O'Mara A, Yonkers R, Kordower JH.

Neurobiol Dis. 2018 Apr;112:106-118. doi: 10.1016/j.nbd.2018.01.008. Epub 2018 Jan 16.

PMID:
29341898
7.

Presence of tau pathology within foetal neural allografts in patients with Huntington's and Parkinson's disease.

Cisbani G, Maxan A, Kordower JH, Planel E, Freeman TB, Cicchetti F.

Brain. 2017 Nov 1;140(11):2982-2992. doi: 10.1093/brain/awx255.

PMID:
29069396
8.

THE CRITICAL ROLE OF NONHUMAN PRIMATES IN MEDICAL RESEARCH.

Friedman H, Ator N, Haigwood N, Newsome W, Allan JS, Golos TG, Kordower JH, Shade RE, Goldberg ME, Bailey MR, Bianchi P.

Pathog Immun. 2017;2(3):352-365. doi: 10.20411/pai.v2i3.186. Epub 2017 Aug 23. No abstract available.

9.

Therapeutic approaches to target alpha-synuclein pathology.

Brundin P, Dave KD, Kordower JH.

Exp Neurol. 2017 Dec;298(Pt B):225-235. doi: 10.1016/j.expneurol.2017.10.003. Epub 2017 Oct 4. Review.

PMID:
28987463
10.

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy.

Obeso JA, Stamelou M, Goetz CG, Poewe W, Lang AE, Weintraub D, Burn D, Halliday GM, Bezard E, Przedborski S, Lehericy S, Brooks DJ, Rothwell JC, Hallett M, DeLong MR, Marras C, Tanner CM, Ross GW, Langston JW, Klein C, Bonifati V, Jankovic J, Lozano AM, Deuschl G, Bergman H, Tolosa E, Rodriguez-Violante M, Fahn S, Postuma RB, Berg D, Marek K, Standaert DG, Surmeier DJ, Olanow CW, Kordower JH, Calabresi P, Schapira AHV, Stoessl AJ.

Mov Disord. 2017 Sep;32(9):1264-1310. doi: 10.1002/mds.27115. Review.

PMID:
28887905
11.

Novel oligodendroglial alpha synuclein viral vector models of multiple system atrophy: studies in rodents and nonhuman primates.

Mandel RJ, Marmion DJ, Kirik D, Chu Y, Heindel C, McCown T, Gray SJ, Kordower JH.

Acta Neuropathol Commun. 2017 Jun 16;5(1):47. doi: 10.1186/s40478-017-0451-7.

12.

Cryopreservation Maintains Functionality of Human iPSC Dopamine Neurons and Rescues Parkinsonian Phenotypes In Vivo.

Wakeman DR, Hiller BM, Marmion DJ, McMahon CW, Corbett GT, Mangan KP, Ma J, Little LE, Xie Z, Perez-Rosello T, Guzman JN, Surmeier DJ, Kordower JH.

Stem Cell Reports. 2017 Jul 11;9(1):149-161. doi: 10.1016/j.stemcr.2017.04.033. Epub 2017 Jun 1.

13.

Endocytic vesicle rupture is a conserved mechanism of cellular invasion by amyloid proteins.

Flavin WP, Bousset L, Green ZC, Chu Y, Skarpathiotis S, Chaney MJ, Kordower JH, Melki R, Campbell EM.

Acta Neuropathol. 2017 Oct;134(4):629-653. doi: 10.1007/s00401-017-1722-x. Epub 2017 May 19.

PMID:
28527044
14.

Aging and Parkinson's disease: Different sides of the same coin?

Collier TJ, Kanaan NM, Kordower JH.

Mov Disord. 2017 Jul;32(7):983-990. doi: 10.1002/mds.27037. Epub 2017 May 18. Review.

15.

α-Synuclein nonhuman primate models of Parkinson's disease.

Marmion DJ, Kordower JH.

J Neural Transm (Vienna). 2018 Mar;125(3):385-400. doi: 10.1007/s00702-017-1720-0. Epub 2017 Apr 22. Review.

PMID:
28434076
16.

What would Dr. James Parkinson think today? parcelling out the circuitry of levodopa-induced dyskinesias.

Kordower JH.

Mov Disord. 2017 Apr;32(4):483-484. doi: 10.1002/mds.27024. No abstract available.

PMID:
28425143
17.

The Potential Role of Gut-Derived Inflammation in Multiple System Atrophy.

Engen PA, Dodiya HB, Naqib A, Forsyth CB, Green SJ, Voigt RM, Kordower JH, Mutlu EA, Shannon KM, Keshavarzian A.

J Parkinsons Dis. 2017;7(2):331-346. doi: 10.3233/JPD-160991.

PMID:
28234259
18.

Targeting α-Synuclein as a therapy for Parkinson's disease: The battle begins.

Olanow CW, Kordower JH.

Mov Disord. 2017 Feb;32(2):203-207. doi: 10.1002/mds.26935. No abstract available.

PMID:
28218461
19.

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease.

Lee JM, Derkinderen P, Kordower JH, Freeman R, Munoz DG, Kremer T, Zago W, Hutten SJ, Adler CH, Serrano GE, Beach TG.

J Neuropathol Exp Neurol. 2017 Jan 1;76(1):2-15. doi: 10.1093/jnen/nlw103. Review.

PMID:
28069931
20.

Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.

Ghosh A, Tyson T, George S, Hildebrandt EN, Steiner JA, Madaj Z, Schulz E, Machiela E, McDonald WG, Escobar Galvis ML, Kordower JH, Van Raamsdonk JM, Colca JR, Brundin P.

Sci Transl Med. 2016 Dec 7;8(368):368ra174.

PMID:
27928028
21.

Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient.

Kordower JH, Goetz CG, Chu Y, Halliday GM, Nicholson DA, Musial TF, Marmion DJ, Stoessl AJ, Sossi V, Freeman TB, Olanow CW.

Ann Neurol. 2017 Jan;81(1):46-57. doi: 10.1002/ana.24820. Epub 2017 Jan 6.

22.

Mechanisms for cell-to-cell propagation no longer lag behind.

Kordower JH, Brundin P.

Mov Disord. 2016 Dec;31(12):1798-1799. doi: 10.1002/mds.26879. Epub 2016 Nov 22. No abstract available.

PMID:
27873365
23.

Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects.

Beach TG, Corbillé AG, Letournel F, Kordower JH, Kremer T, Munoz DG, Intorcia A, Hentz J, Adler CH, Sue LI, Walker J, Serrano G, Derkinderen P.

J Parkinsons Dis. 2016 Oct 19;6(4):761-770.

24.

Is Axonal Degeneration a Key Early Event in Parkinson's Disease?

Kurowska Z, Kordower JH, Stoessl AJ, Burke RE, Brundin P, Yue Z, Brady ST, Milbrandt J, Trapp BD, Sherer TB, Medicetty S.

J Parkinsons Dis. 2016 Oct 19;6(4):703-707. Review.

PMID:
27497486
25.

Parkinsonian monkeys with prior levodopa-induced dyskinesias followed by fetal dopamine precursor grafts do not display graft-induced dyskinesias.

Kordower JH, Vinuela A, Chu Y, Isacson O, Redmond DE Jr.

J Comp Neurol. 2017 Feb 15;525(3):498-512. doi: 10.1002/cne.24081. Epub 2016 Aug 29.

PMID:
27418401
26.

How strong is the evidence that Parkinson's disease is a prion disorder?

Brundin P, Ma J, Kordower JH.

Curr Opin Neurol. 2016 Aug;29(4):459-66. doi: 10.1097/WCO.0000000000000349. Review.

27.

Fetal grafts for Parkinson's disease: Decades in the making.

Kordower JH, Olanow CW.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6332-4. doi: 10.1073/pnas.1606342113. Epub 2016 May 31. No abstract available.

28.

Neutralization of RANTES and Eotaxin Prevents the Loss of Dopaminergic Neurons in a Mouse Model of Parkinson Disease.

Chandra G, Rangasamy SB, Roy A, Kordower JH, Pahan K.

J Biol Chem. 2016 Jul 15;291(29):15267-81. doi: 10.1074/jbc.M116.714824. Epub 2016 May 12.

29.

TDP-43 Proteinopathy: Aggregation and Propagation in the Pathogenesis of Amyotrophic Lateral Sclerosis.

Meriggioli MN, Kordower JH.

Mov Disord. 2016 Aug;31(8):1139. doi: 10.1002/mds.26645. Epub 2016 May 23. No abstract available.

PMID:
27214572
30.

Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies.

Corbillé AG, Letournel F, Kordower JH, Lee J, Shanes E, Neunlist M, Munoz DG, Derkinderen P, Beach TG.

Acta Neuropathol Commun. 2016 Apr 4;4:35. doi: 10.1186/s40478-016-0305-8.

31.

Alterations in Activity-Dependent Neuroprotective Protein in Sporadic and Experimental Parkinson's Disease.

Chu Y, Morfini GA, Kordower JH.

J Parkinsons Dis. 2016;6(1):77-97. doi: 10.3233/JPD-160812.

PMID:
27003787
32.

Preface.

Stefanova N, Kordower JH, Wenning GK.

Mov Disord. 2016 Feb;31(2):151. doi: 10.1002/mds.26554. No abstract available.

PMID:
26853078
33.

Parkinson's disease and prion disease: Straining the comparison.

Fung VS, Kordower JH.

Mov Disord. 2015 Nov;30(13):1727. doi: 10.1002/mds.26437. Review. No abstract available.

PMID:
26769458
34.

Trophic factors for Parkinson's disease: To live or let die.

Olanow CW, Bartus RT, Volpicelli-Daley LA, Kordower JH.

Mov Disord. 2015 Nov;30(13):1715-24. doi: 10.1002/mds.26426. Review.

PMID:
26769457
35.

AAV2-Neurturin for Parkinson's Disease: What Lessons Have We Learned?

Kordower JH.

Methods Mol Biol. 2016;1382:485-90. doi: 10.1007/978-1-4939-3271-9_32.

PMID:
26611606
36.

Broad distribution of ataxin 1 silencing in rhesus cerebella for spinocerebellar ataxia type 1 therapy.

Keiser MS, Kordower JH, Gonzalez-Alegre P, Davidson BL.

Brain. 2015 Dec;138(Pt 12):3555-66. doi: 10.1093/brain/awv292. Epub 2015 Oct 21.

37.

Alpha-synuclein propagation: New insights from animal models.

Dehay B, Vila M, Bezard E, Brundin P, Kordower JH.

Mov Disord. 2016 Feb;31(2):161-8. doi: 10.1002/mds.26370. Epub 2015 Sep 8. Review.

PMID:
26347034
38.

PGC-1α Promoter Methylation in Parkinson's Disease.

Su X, Chu Y, Kordower JH, Li B, Cao H, Huang L, Nishida M, Song L, Wang D, Federoff HJ.

PLoS One. 2015 Aug 28;10(8):e0134087. doi: 10.1371/journal.pone.0134087. eCollection 2015.

39.

The native form of α-Synuclein: Monomer, tetramer, or a combination in equilibrium.

Corbett GT, Kordower JH.

Mov Disord. 2015 Dec;30(14):1870. doi: 10.1002/mds.26361. Epub 2015 Jul 31. Review. No abstract available.

PMID:
26230906
40.

Analysis of YFP(J16)-R6/2 reporter mice and postmortem brains reveals early pathology and increased vulnerability of callosal axons in Huntington's disease.

Gatto RG, Chu Y, Ye AQ, Price SD, Tavassoli E, Buenaventura A, Brady ST, Magin RL, Kordower JH, Morfini GA.

Hum Mol Genet. 2015 Sep 15;24(18):5285-98. doi: 10.1093/hmg/ddv248. Epub 2015 Jun 29.

41.

Gene delivery of neurturin to putamen and substantia nigra in Parkinson disease: A double-blind, randomized, controlled trial.

Warren Olanow C, Bartus RT, Baumann TL, Factor S, Boulis N, Stacy M, Turner DA, Marks W, Larson P, Starr PA, Jankovic J, Simpson R, Watts R, Guthrie B, Poston K, Henderson JM, Stern M, Baltuch G, Goetz CG, Herzog C, Kordower JH, Alterman R, Lozano AM, Lang AE.

Ann Neurol. 2015 Aug;78(2):248-57. doi: 10.1002/ana.24436. Epub 2015 Jun 10.

PMID:
26061140
42.

The prion hypothesis of Parkinson's disease.

Chu Y, Kordower JH.

Curr Neurol Neurosci Rep. 2015 May;15(5):28. doi: 10.1007/s11910-015-0549-x.

PMID:
25868519
43.

Post-mortem assessment of the short and long-term effects of the trophic factor neurturin in patients with α-synucleinopathies.

Bartus RT, Kordower JH, Johnson EM Jr, Brown L, Kruegel BR, Chu Y, Baumann TL, Lang AE, Olanow CW, Herzog CD.

Neurobiol Dis. 2015 Jun;78:162-71. doi: 10.1016/j.nbd.2015.03.023. Epub 2015 Apr 2.

PMID:
25841760
44.

Attenuation of microglial RANTES by NEMO-binding domain peptide inhibits the infiltration of CD8(+) T cells in the nigra of hemiparkinsonian monkey.

Roy A, Mondal S, Kordower JH, Pahan K.

Neuroscience. 2015 Aug 27;302:36-46. doi: 10.1016/j.neuroscience.2015.03.011. Epub 2015 Mar 14.

45.

Gene therapy for Parkinson's disease: still a hot topic?

Kordower JH.

Neuropsychopharmacology. 2015 Jan;40(1):255-6. doi: 10.1038/npp.2014.235. Review. No abstract available.

46.

Peripheral alpha-synuclein and Parkinson's disease.

Olanow CW, Wakeman DR, Kordower JH.

Mov Disord. 2014 Jul;29(8):963-6. doi: 10.1002/mds.25966. No abstract available.

PMID:
25043799
47.

Misfolded proteins in Huntington disease fetal grafts: further evidence of cell-to-cell transfer?

Kordower JH, Halliday G.

Ann Neurol. 2014 Jul;76(1):20-1. doi: 10.1002/ana.24205. Epub 2014 Jul 9. No abstract available.

PMID:
24961209
48.

Special issue on stem cells.

Wakeman DR, Kordower JH.

J Comp Neurol. 2014 Aug 15;522(12):2689-90. doi: 10.1002/cne.23611. No abstract available.

PMID:
24942075
49.

Progression of intestinal permeability changes and alpha-synuclein expression in a mouse model of Parkinson's disease.

Kelly LP, Carvey PM, Keshavarzian A, Shannon KM, Shaikh M, Bakay RA, Kordower JH.

Mov Disord. 2014 Jul;29(8):999-1009. doi: 10.1002/mds.25736. Epub 2013 Nov 4.

50.

The prion hypothesis of Parkinson's disease: this hot topic just got hotter.

Kordower JH.

Mov Disord. 2014 Jul;29(8):988. doi: 10.1002/mds.25918. Epub 2014 May 27. No abstract available.

PMID:
24867814

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