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Items: 32

1.

Thrombomodulin expressing monocytes are associated with low risk features in myelodysplastic syndromes and dampen excessive immune activation.

van Leeuwen-Kerkhoff N, Westers TM, Poddighe PJ, de Gruijl TD, Kordasti S, van de Loosdrecht AA.

Haematologica. 2019 Jul 4. pii: haematol.2019.219303. doi: 10.3324/haematol.2019.219303. [Epub ahead of print]

2.

Essential thrombocythaemia treated with recombinant interferon: 'real world' United Kingdom referral centre experience.

Desterro J, McLornan DP, Curto Garcia N, O'Sullivan J, Alimam S, Keohane C, Woodley C, Francis Y, Kordasti S, Radia DH, Harrison CN.

Br J Haematol. 2019 Aug;186(4):561-564. doi: 10.1111/bjh.15968. Epub 2019 May 15.

PMID:
31090926
3.

Human retinoic acid-regulated CD161+ regulatory T cells support wound repair in intestinal mucosa.

Povoleri GAM, Nova-Lamperti E, Scottà C, Fanelli G, Chen YC, Becker PD, Boardman D, Costantini B, Romano M, Pavlidis P, McGregor R, Pantazi E, Chauss D, Sun HW, Shih HY, Cousins DJ, Cooper N, Powell N, Kemper C, Pirooznia M, Laurence A, Kordasti S, Kazemian M, Lombardi G, Afzali B.

Nat Immunol. 2018 Dec;19(12):1403-1414. doi: 10.1038/s41590-018-0230-z. Epub 2018 Nov 5.

4.

Human Bone Marrow-Derived Myeloid Dendritic Cells Show an Immature Transcriptional and Functional Profile Compared to Their Peripheral Blood Counterparts and Separate from Slan+ Non-Classical Monocytes.

van Leeuwen-Kerkhoff N, Lundberg K, Westers TM, Kordasti S, Bontkes HJ, Lindstedt M, de Gruijl TD, van de Loosdrecht AA.

Front Immunol. 2018 Jul 16;9:1619. doi: 10.3389/fimmu.2018.01619. eCollection 2018.

5.

Repurposing Tin Mesoporphyrin as an Immune Checkpoint Inhibitor Shows Therapeutic Efficacy in Preclinical Models of Cancer.

Muliaditan T, Opzoomer JW, Caron J, Okesola M, Kosti P, Lall S, Van Hemelrijck M, Dazzi F, Tutt A, Grigoriadis A, Gillett CE, Madden SF, Burchell JM, Kordasti S, Diebold SS, Spicer JF, Arnold JN.

Clin Cancer Res. 2018 Apr 1;24(7):1617-1628. doi: 10.1158/1078-0432.CCR-17-2587. Epub 2018 Jan 16.

6.

Transcriptional profiling reveals functional dichotomy between human slan+ non-classical monocytes and myeloid dendritic cells.

van Leeuwen-Kerkhoff N, Lundberg K, Westers TM, Kordasti S, Bontkes HJ, de Gruijl TD, Lindstedt M, van de Loosdrecht AA.

J Leukoc Biol. 2017 Oct;102(4):1055-1068. doi: 10.1189/jlb.3MA0117-037R. Epub 2017 Jul 18.

PMID:
28720687
7.

Cluster stability in the analysis of mass cytometry data.

Melchiotti R, Gracio F, Kordasti S, Todd AK, de Rinaldis E.

Cytometry A. 2017 Jan;91(1):73-84. doi: 10.1002/cyto.a.23001. Epub 2016 Oct 18.

8.

Baseline cytokine profiling identifies novel risk factors for invasive fungal disease among haematology patients undergoing intensive chemotherapy or haematopoietic stem cell transplantation.

Ceesay MM, Kordasti S, Rufaie E, Lea N, Smith M, Wade J, Douiri A, Mufti GJ, Pagliuca A.

J Infect. 2016 Sep;73(3):280-8. doi: 10.1016/j.jinf.2016.04.040. Epub 2016 Jun 22.

PMID:
27343564
9.

Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment.

Kordasti S, Costantini B, Seidl T, Perez Abellan P, Martinez Llordella M, McLornan D, Diggins KE, Kulasekararaj A, Benfatto C, Feng X, Smith A, Mian SA, Melchiotti R, de Rinaldis E, Ellis R, Petrov N, Povoleri GA, Chung SS, Thomas NS, Farzaneh F, Irish JM, Heck S, Young NS, Marsh JC, Mufti GJ.

Blood. 2016 Sep 1;128(9):1193-205. doi: 10.1182/blood-2016-03-703702. Epub 2016 Jun 8.

10.

"Solid Red Line": An Observational Study on Death from Refractory Intracranial Hypertension.

Czosnyka M, Aries M, Weersink C, Wolf S, Budohoski K, Dias C, Lewis P, Smielewski P, Kordasti S.

Acta Neurochir Suppl. 2016;122:113-6. doi: 10.1007/978-3-319-22533-3_22.

PMID:
27165888
11.

Expansion of myeloid derived suppressor cells correlates with number of T regulatory cells and disease progression in myelodysplastic syndrome.

Kittang AO, Kordasti S, Sand KE, Costantini B, Kramer AM, Perezabellan P, Seidl T, Rye KP, Hagen KM, Kulasekararaj A, Bruserud Ø, Mufti GJ.

Oncoimmunology. 2015 Jun 24;5(2):e1062208. eCollection 2016 Feb.

12.

Autoimmune diseases and myelodysplastic syndromes.

Komrokji RS, Kulasekararaj A, Al Ali NH, Kordasti S, Bart-Smith E, Craig BM, Padron E, Zhang L, Lancet JE, Pinilla-Ibarz J, List AF, Mufti GJ, Epling-Burnette PK.

Am J Hematol. 2016 May;91(5):E280-3. doi: 10.1002/ajh.24333. Epub 2016 Apr 4.

13.

JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells.

Keohane C, Kordasti S, Seidl T, Perez Abellan P, Thomas NS, Harrison CN, McLornan DP, Mufti GJ.

Br J Haematol. 2015 Oct;171(1):60-73. doi: 10.1111/bjh.13519. Epub 2015 Jun 15.

PMID:
26075866
14.

Chronic relapsing remitting Sweet syndrome--a harbinger of myelodysplastic syndrome.

Kulasekararaj AG, Kordasti S, Basu T, Salisbury JR, Mufti GJ, du Vivier AW.

Br J Haematol. 2015 Sep;170(5):649-56. doi: 10.1111/bjh.13485. Epub 2015 May 12.

PMID:
25962438
15.

Successful treatment of aplastic anaemia associated with HIV infection with eltrombopag: implications for a possible immunomodulatory role.

Bart-Smith EE, Kordasti S, Kulasekararaj AG, Richardson D, Mufti GJ, Marsh JC.

AIDS. 2014 Nov 28;28(18):2786-8. doi: 10.1097/QAD.0000000000000504.

PMID:
25333665
16.

Dendritic cells in myelodysplastic syndromes: from pathogenesis to immunotherapy.

Kerkhoff N, Bontkes HJ, Westers TM, de Gruijl TD, Kordasti S, van de Loosdrecht AA.

Immunotherapy. 2013 Jun;5(6):621-37. doi: 10.2217/imt.13.51. Review.

PMID:
23725285
17.

CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.

Afzali B, Mitchell PJ, Edozie FC, Povoleri GA, Dowson SE, Demandt L, Walter G, Canavan JB, Scotta C, Menon B, Chana PS, Khamri W, Kordasti SY, Heck S, Grimbacher B, Tree T, Cope AP, Taams LS, Lechler RI, John S, Lombardi G.

Eur J Immunol. 2013 Aug;43(8):2043-54. doi: 10.1002/eji.201243296. Epub 2013 Jul 3.

18.

Comparison of regulatory T cells in hemodialysis patients and healthy controls: implications for cell therapy in transplantation.

Afzali B, Edozie FC, Fazekasova H, Scottà C, Mitchell PJ, Canavan JB, Kordasti SY, Chana PS, Ellis R, Lord GM, John S, Hilton R, Lechler RI, Lombardi G.

Clin J Am Soc Nephrol. 2013 Aug;8(8):1396-405. doi: 10.2215/CJN.12931212. Epub 2013 Apr 11.

19.

The effects of 5-azacytidine on the function and number of regulatory T cells and T-effectors in myelodysplastic syndrome.

Costantini B, Kordasti SY, Kulasekararaj AG, Jiang J, Seidl T, Abellan PP, Mohamedali A, Thomas NS, Farzaneh F, Mufti GJ.

Haematologica. 2013 Aug;98(8):1196-205. doi: 10.3324/haematol.2012.074823. Epub 2012 Dec 14.

20.

Rationale for the clinical application of flow cytometry in patients with myelodysplastic syndromes: position paper of an International Consortium and the European LeukemiaNet Working Group.

van de Loosdrecht AA, Ireland R, Kern W, Della Porta MG, Alhan C, Balleisen JS, Bettelheim P, Bowen DT, Burbury K, Eidenschink L, Cazzola M, Chu SS, Cullen M, Cutler JA, Dräger AM, Feuillard J, Fenaux P, Font P, Germing U, Haase D, Hellström-Lindberg E, Johansson U, Kordasti S, Loken MR, Malcovati L, te Marvelde JG, Matarraz S, Milne T, Moshaver B, Mufti GJ, Nikolova V, Ogata K, Oelschlaegel U, Orfao A, Ossenkoppele GJ, Porwit A, Platzbecker U, Preijers F, Psarra K, Richards SJ, Subirá D, Seymour JF, Tindell V, Vallespi T, Valent P, van der Velden VH, Wells DA, de Witte TM, Zettl F, Béné MC, Westers TM.

Leuk Lymphoma. 2013 Mar;54(3):472-5. doi: 10.3109/10428194.2012.718341. Epub 2012 Sep 14. Review.

PMID:
22916713
21.

Prospective study of rabbit antithymocyte globulin and cyclosporine for aplastic anemia from the EBMT Severe Aplastic Anaemia Working Party.

Marsh JC, Bacigalupo A, Schrezenmeier H, Tichelli A, Risitano AM, Passweg JR, Killick SB, Warren AJ, Foukaneli T, Aljurf M, Al-Zahrani HA, Höchsmann B, Schafhausen P, Roth A, Franzke A, Brummendorf TH, Dufour C, Oneto R, Sedgwick P, Barrois A, Kordasti S, Elebute MO, Mufti GJ, Socie G; European Blood and Marrow Transplant Group Severe Aplastic Anaemia Working Party.

Blood. 2012 Jun 7;119(23):5391-6. doi: 10.1182/blood-2012-02-407684. Epub 2012 Apr 27. Erratum in: Blood. 2013 Jun 20;121(25):5104. Höchsmann, Britta [added].

22.

Standardization of flow cytometry in myelodysplastic syndromes: a report from an international consortium and the European LeukemiaNet Working Group.

Westers TM, Ireland R, Kern W, Alhan C, Balleisen JS, Bettelheim P, Burbury K, Cullen M, Cutler JA, Della Porta MG, Dräger AM, Feuillard J, Font P, Germing U, Haase D, Johansson U, Kordasti S, Loken MR, Malcovati L, te Marvelde JG, Matarraz S, Milne T, Moshaver B, Mufti GJ, Ogata K, Orfao A, Porwit A, Psarra K, Richards SJ, Subirá D, Tindell V, Vallespi T, Valent P, van der Velden VH, de Witte TM, Wells DA, Zettl F, Béné MC, van de Loosdrecht AA.

Leukemia. 2012 Jul;26(7):1730-41. doi: 10.1038/leu.2012.30. Epub 2012 Feb 6.

PMID:
22307178
23.

Functional characterization of CD4+ T cells in aplastic anemia.

Kordasti S, Marsh J, Al-Khan S, Jiang J, Smith A, Mohamedali A, Abellan PP, Veen C, Costantini B, Kulasekararaj AG, Benson-Quarm N, Seidl T, Mian SA, Farzaneh F, Mufti GJ.

Blood. 2012 Mar 1;119(9):2033-43. doi: 10.1182/blood-2011-08-368308. Epub 2011 Dec 2.

24.

Imbalance of effector and regulatory CD4 T cells is associated with graft-versus-host disease after hematopoietic stem cell transplantation using a reduced intensity conditioning regimen and alemtuzumab.

Matthews K, Lim Z, Afzali B, Pearce L, Abdallah A, Kordasti S, Pagliuca A, Lombardi G, Madrigal JA, Mufti GJ, Barber LD.

Haematologica. 2009 Jul;94(7):956-66. doi: 10.3324/haematol.2008.003103. Epub 2009 Jun 2.

25.

Human CD80/IL2 lentivirus-transduced acute myeloid leukaemia (AML) cells promote natural killer (NK) cell activation and cytolytic activity: implications for a phase I clinical study.

Ingram W, Chan L, Guven H, Darling D, Kordasti S, Hardwick N, Barber L, Mufti GJ, Farzaneh F.

Br J Haematol. 2009 Jun;145(6):749-60. doi: 10.1111/j.1365-2141.2009.07684.x. Epub 2009 Apr 20.

PMID:
19388935
26.

Human CD80/IL2 lentivirus transduced acute myeloid leukaemia cells enhance cytolytic activity in vitro in spite of an increase in regulatory CD4+ T cells in a subset of cultures.

Ingram W, Kordasti S, Chan L, Barber LD, Tye GJ, Hardwick N, Mufti GJ, Farzaneh F.

Cancer Immunol Immunother. 2009 Oct;58(10):1679-90. doi: 10.1007/s00262-009-0679-6. Epub 2009 Mar 13.

PMID:
19283381
27.

IL-17-producing CD4(+) T cells, pro-inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome.

Kordasti SY, Afzali B, Lim Z, Ingram W, Hayden J, Barber L, Matthews K, Chelliah R, Guinn B, Lombardi G, Farzaneh F, Mufti GJ.

Br J Haematol. 2009 Apr;145(1):64-72. doi: 10.1111/j.1365-2141.2009.07593.x. Epub 2009 Feb 3.

PMID:
19210506
28.

CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS).

Kordasti SY, Ingram W, Hayden J, Darling D, Barber L, Afzali B, Lombardi G, Wlodarski MW, Maciejewski JP, Farzaneh F, Mufti GJ.

Blood. 2007 Aug 1;110(3):847-50. Epub 2007 Apr 5.

29.

Rotavirus infection is not associated with small intestinal fluid secretion in the adult mouse.

Kordasti S, Istrate C, Banasaz M, Rottenberg M, Sjövall H, Lundgren O, Svensson L.

J Virol. 2006 Nov;80(22):11355-61. Epub 2006 Aug 30.

30.

Effects of cholera toxin on the potential difference and motor responses induced by distension in the rat proximal small intestine in vivo.

Kordasti S, Sapnara M, Thomas EA, Lindstrom E, Forsman M, Bornstein JC, Sjövall H.

Am J Physiol Gastrointest Liver Physiol. 2006 May;290(5):G948-58. Epub 2005 Dec 15.

31.

Serotonin and vasoactive intestinal peptide antagonists attenuate rotavirus diarrhoea.

Kordasti S, Sjövall H, Lundgren O, Svensson L.

Gut. 2004 Jul;53(7):952-7.

32.

Role of the enteric nervous system in the fluid and electrolyte secretion of rotavirus diarrhea.

Lundgren O, Peregrin AT, Persson K, Kordasti S, Uhnoo I, Svensson L.

Science. 2000 Jan 21;287(5452):491-5.

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