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Items: 11

1.

St. John's Wort Attenuates Colorectal Carcinogenesis in Mice through Suppression of Inflammatory Signaling.

Manna SK, Golla S, Golla JP, Tanaka N, Cai Y, Takahashi S, Krausz KW, Matsubara T, Korboukh I, Gonzalez FJ.

Cancer Prev Res (Phila). 2015 Sep;8(9):786-95. doi: 10.1158/1940-6207.CAPR-14-0113. Epub 2015 Jun 11.

2.

Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.

Liu F, Li F, Ma A, Dobrovetsky E, Dong A, Gao C, Korboukh I, Liu J, Smil D, Brown PJ, Frye SV, Arrowsmith CH, Schapira M, Vedadi M, Jin J.

J Med Chem. 2013 Mar 14;56(5):2110-24. doi: 10.1021/jm3018332. Epub 2013 Feb 27.

3.

An allosteric inhibitor of protein arginine methyltransferase 3.

Siarheyeva A, Senisterra G, Allali-Hassani A, Dong A, Dobrovetsky E, Wasney GA, Chau I, Marcellus R, Hajian T, Liu F, Korboukh I, Smil D, Bolshan Y, Min J, Wu H, Zeng H, Loppnau P, Poda G, Griffin C, Aman A, Brown PJ, Jin J, Al-Awar R, Arrowsmith CH, Schapira M, Vedadi M.

Structure. 2012 Aug 8;20(8):1425-35. doi: 10.1016/j.str.2012.06.001. Epub 2012 Jul 12.

4.

Orally active adenosine A(1) receptor agonists with antinociceptive effects in mice.

Korboukh I, Hull-Ryde EA, Rittiner JE, Randhawa AS, Coleman J, Fitzpatrick BJ, Setola V, Janzen WP, Frye SV, Zylka MJ, Jin J.

J Med Chem. 2012 Jul 26;55(14):6467-77. doi: 10.1021/jm3004834. Epub 2012 Jul 16.

5.

AMP is an adenosine A1 receptor agonist.

Rittiner JE, Korboukh I, Hull-Ryde EA, Jin J, Janzen WP, Frye SV, Zylka MJ.

J Biol Chem. 2012 Feb 17;287(8):5301-9. doi: 10.1074/jbc.M111.291666. Epub 2012 Jan 3.

6.

Targeting protein lysine methylation and demethylation in cancers.

He Y, Korboukh I, Jin J, Huang J.

Acta Biochim Biophys Sin (Shanghai). 2012 Jan;44(1):70-9. doi: 10.1093/abbs/gmr109. Review.

7.

Targets in epigenetics: inhibiting the methyl writers of the histone code.

Yost JM, Korboukh I, Liu F, Gao C, Jin J.

Curr Chem Genomics. 2011;5(Suppl 1):72-84. doi: 10.2174/1875397301005010072. Epub 2011 Aug 22.

8.

Further studies of intramolecular Michael reactions of nitrosoalkenes for construction of functionalized bridged ring systems.

Kumar P, Li P, Korboukh I, Wang TL, Yennawar H, Weinreb SM.

J Org Chem. 2011 Apr 1;76(7):2094-101. doi: 10.1021/jo1024392. Epub 2011 Feb 28.

9.

A mild, efficient method for the oxidation of alpha-diazo-beta-hydroxyesters to alpha-diazo-beta-ketoesters.

Li P, Majireck MM, Korboukh I, Weinreb SM.

Tetrahedron Lett. 2008 May 5;49(19):3162-3164.

10.

Construction of bridged and fused ring systems via intramolecular Michael reactions of vinylnitroso compounds.

Korboukh I, Kumar P, Weinreb SM.

J Am Chem Soc. 2007 Aug 29;129(34):10342-3. Epub 2007 Aug 3. No abstract available.

11.

Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase.

De La Rosa M, Kim HW, Gunic E, Jenket C, Boyle U, Koh YH, Korboukh I, Allan M, Zhang W, Chen H, Xu W, Nilar S, Yao N, Hamatake R, Lang SA, Hong Z, Zhang Z, Girardet JL.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4444-9. Epub 2006 Jun 27.

PMID:
16806925

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