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Items: 1 to 50 of 107

1.

Acquisition of IgG to ICAM-1-binding DBLβ domains in the Plasmodium falciparum erythrocyte membrane protein 1 antigen family varies between Groups A, B and C.

Olsen RW, Ecklu-Mensah G, Bengtsson A, Ofori MF, Kusi KA, Koram KA, Hviid L, Adams Y, Jensen ATR.

Infect Immun. 2019 Jul 15. pii: IAI.00224-19. doi: 10.1128/IAI.00224-19. [Epub ahead of print]

2.

Antigenicity and immune correlate assessment of seven Plasmodium falciparum antigens in a longitudinal infant cohort from northern Ghana.

Kusi KA, Aguiar J, Kumordjie S, Aggor F, Bolton J, Renner A, Kyei-Baafour E, Puplampu N, Belmonte M, Dodoo D, Gyan BA, Ofori MF, Oduro AR, Atuguba F, Koram KA, Adams N, Letizia A, Villasante E, Sedegah M.

Sci Rep. 2019 Jun 13;9(1):8621. doi: 10.1038/s41598-019-45092-4.

3.

Challenges and perceptions of implementing mass testing, treatment and tracking in malaria control: a qualitative study in Pakro sub-district of Ghana.

Ndong IC, Okyere D, Enos JY, Amambua-Ngwa A, Merle CSC, Nyarko A, Koram KA, Ahorlu CS.

BMC Public Health. 2019 Jun 6;19(1):695. doi: 10.1186/s12889-019-7037-1.

4.

Malaria causes long-term effects on markers of iron status in children: a critical assessment of existing clinical and epidemiological tools.

Castberg FC, Sarbah EW, Koram KA, Opoku N, Ofori MF, Styrishave B, Hviid L, Kurtzhals JAL.

Malar J. 2018 Dec 11;17(1):464. doi: 10.1186/s12936-018-2609-6.

5.

Impact of indoor residual spraying on malaria parasitaemia in the Bunkpurugu-Yunyoo District in northern Ghana.

Abuaku B, Ahorlu C, Psychas P, Ricks P, Oppong S, Mensah S, Sackey W, Koram KA.

Parasit Vectors. 2018 Oct 23;11(1):555. doi: 10.1186/s13071-018-3130-z.

6.

Reduced transmission of Mycobacterium africanum compared to Mycobacterium tuberculosis in urban West Africa.

Asare P, Asante-Poku A, Prah DA, Borrell S, Osei-Wusu S, Otchere ID, Forson A, Adjapong G, Koram KA, Gagneux S, Yeboah-Manu D.

Int J Infect Dis. 2018 Aug;73:30-42. doi: 10.1016/j.ijid.2018.05.014. Epub 2018 Jun 4.

7.

In vitro antiprotozoan activity and mechanisms of action of selected Ghanaian medicinal plants against Trypanosoma, Leishmania, and Plasmodium parasites.

Ohashi M, Amoa-Bosompem M, Kwofie KD, Agyapong J, Adegle R, Sakyiamah MM, Ayertey F, Owusu KB, Tuffour I, Atchoglo P, Tung NH, Uto T, Aboagye F, Appiah AA, Appiah-Opong R, Nyarko AK, Anyan WK, Ayi I, Boakye DA, Koram KA, Edoh D, Yamaoka S, Shoyama Y, Ohta N.

Phytother Res. 2018 Aug;32(8):1617-1630. doi: 10.1002/ptr.6093. Epub 2018 May 7.

PMID:
29733118
8.

Information gaps in surveillance data and effects on the Ghanaian response to the Ebola outbreak in West Africa.

Awini EA, Bonney JHK, Frimpong JA, Ampofo WK, Koram KA.

Ghana Med J. 2017 Sep;51(3):115-119.

9.

Improved prediction of gestational hypertension by inclusion of placental growth factor and pregnancy associated plasma protein-a in a sample of Ghanaian women.

Antwi E, Klipstein-Grobusch K, Browne JL, Schielen PC, Koram KA, Agyepong IA, Grobbee DE.

Reprod Health. 2018 Mar 27;15(1):56. doi: 10.1186/s12978-018-0492-9.

10.

Prevalence of Plasmodium falciparum delayed clearance associated polymorphisms in adaptor protein complex 2 mu subunit (pfap2mu) and ubiquitin specific protease 1 (pfubp1) genes in Ghanaian isolates.

Adams T, Ennuson NAA, Quashie NB, Futagbi G, Matrevi S, Hagan OCK, Abuaku B, Koram KA, Duah NO.

Parasit Vectors. 2018 Mar 12;11(1):175. doi: 10.1186/s13071-018-2762-3.

11.

Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana.

Kusi KA, Manu EA, Manful Gwira T, Kyei-Baafour E, Dickson EK, Amponsah JA, Remarque EJ, Faber BW, Kocken CHM, Dodoo D, Gyan BA, Awandare GA, Atuguba F, Oduro AR, Koram KA.

PLoS One. 2017 Sep 25;12(9):e0185303. doi: 10.1371/journal.pone.0185303. eCollection 2017.

12.

Efficacy of Artesunate/Amodiaquine in the Treatment of Uncomplicated Malaria among Children in Ghana.

Abuaku BK, Mensah BA, Ofori MF, Myers-Hansen J, Derkyi-Kwarteng AN, Essilfie F, Dokurugu M, Amoakoh E, Koram KA, Ghansah A.

Am J Trop Med Hyg. 2017 Sep;97(3):690-695. doi: 10.4269/ajtmh.15-0826. Epub 2017 Jul 27.

13.

Lack of Geospatial Population Structure Yet Significant Linkage Disequilibrium in the Reservoir of Plasmodium falciparum in Bongo District, Ghana.

Ruybal-Pesántez S, Tiedje KE, Rorick MM, Amenga-Etego L, Ghansah A, R Oduro A, Koram KA, Day KP.

Am J Trop Med Hyg. 2017 Oct;97(4):1180-1189. doi: 10.4269/ajtmh.17-0119. Epub 2017 Jul 19.

14.

Seasonal Variation in the Epidemiology of Asymptomatic Plasmodium falciparum Infections across Two Catchment Areas in Bongo District, Ghana.

Tiedje KE, Oduro AR, Agongo G, Anyorigiya T, Azongo D, Awine T, Ghansah A, Pascual M, Koram KA, Day KP.

Am J Trop Med Hyg. 2017 Jul;97(1):199-212. doi: 10.4269/ajtmh.16-0959.

15.

Development and validation of a prediction model for gestational hypertension in a Ghanaian cohort.

Antwi E, Groenwold RH, Browne JL, Franx A, Agyepong IA, Koram KA, Klipstein-Grobusch K, Grobbee DE.

BMJ Open. 2017 Jan 16;7(1):e012670. doi: 10.1136/bmjopen-2016-012670. Erratum in: BMJ Open. 2017 Feb 2;7(2):e012670corr1.

16.

Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia.

Clarke GM, Rockett K, Kivinen K, Hubbart C, Jeffreys AE, Rowlands K, Jallow M, Conway DJ, Bojang KA, Pinder M, Usen S, Sisay-Joof F, Sirugo G, Toure O, Thera MA, Konate S, Sissoko S, Niangaly A, Poudiougou B, Mangano VD, Bougouma EC, Sirima SB, Modiano D, Amenga-Etego LN, Ghansah A, Koram KA, Wilson MD, Enimil A, Evans J, Amodu OK, Olaniyan S, Apinjoh T, Mugri R, Ndi A, Ndila CM, Uyoga S, Macharia A, Peshu N, Williams TN, Manjurano A, Sepúlveda N, Clark TG, Riley E, Drakeley C, Reyburn H, Nyirongo V, Kachala D, Molyneux M, Dunstan SJ, Phu NH, Quyen NN, Thai CQ, Hien TT, Manning L, Laman M, Siba P, Karunajeewa H, Allen S, Allen A, Davis TM, Michon P, Mueller I, Molloy SF, Campino S, Kerasidou A, Cornelius VJ, Hart L, Shah SS, Band G, Spencer CC, Agbenyega T, Achidi E, Doumbo OK, Farrar J, Marsh K, Taylor T, Kwiatkowski DP; MalariaGEN Consortium.

Elife. 2017 Jan 9;6. pii: e15085. doi: 10.7554/eLife.15085.

17.

Seroprevalence of Antibodies against Plasmodium falciparum Sporozoite Antigens as Predictive Disease Transmission Markers in an Area of Ghana with Seasonal Malaria Transmission.

Kusi KA, Bosomprah S, Kyei-Baafour E, Dickson EK, Tornyigah B, Angov E, Dutta S, Dodoo D, Sedegah M, Koram KA.

PLoS One. 2016 Nov 22;11(11):e0167175. doi: 10.1371/journal.pone.0167175. eCollection 2016.

18.

Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-Immune Adults: A Phase 1, Double-Blinded Placebo Controlled Dosage Escalation Study.

Koram KA, Adu B, Ocran J, Karikari YS, Adu-Amankwah S, Ntiri M, Abuaku B, Dodoo D, Gyan B, Kronmann KC, Nkrumah F.

PLoS One. 2016 Sep 19;11(9):e0163066. doi: 10.1371/journal.pone.0163066. eCollection 2016.

19.

Spatio-Temporal Distribution of Mycobacterium tuberculosis Complex Strains in Ghana.

Yeboah-Manu D, Asare P, Asante-Poku A, Otchere ID, Osei-Wusu S, Danso E, Forson A, Koram KA, Gagneux S.

PLoS One. 2016 Aug 26;11(8):e0161892. doi: 10.1371/journal.pone.0161892. eCollection 2016.

20.

Molecular epidemiology of Mycobacterium africanum in Ghana.

Asante-Poku A, Otchere ID, Osei-Wusu S, Sarpong E, Baddoo A, Forson A, Laryea C, Borrell S, Bonsu F, Hattendorf J, Ahorlu C, Koram KA, Gagneux S, Yeboah-Manu D.

BMC Infect Dis. 2016 Aug 9;16:385. doi: 10.1186/s12879-016-1725-6.

21.

Genetic diversity of Plasmodium falciparum isolates from uncomplicated malaria cases in Ghana over a decade.

Duah NO, Matrevi SA, Quashie NB, Abuaku B, Koram KA.

Parasit Vectors. 2016 Jul 26;9(1):416. doi: 10.1186/s13071-016-1692-1.

22.

Admixture into and within sub-Saharan Africa.

Busby GB, Band G, Si Le Q, Jallow M, Bougama E, Mangano VD, Amenga-Etego LN, Enimil A, Apinjoh T, Ndila CM, Manjurano A, Nyirongo V, Doumba O, Rockett KA, Kwiatkowski DP, Spencer CC; Malaria Genomic Epidemiology Network.

Elife. 2016 Jun 21;5. pii: e15266. doi: 10.7554/eLife.15266.

23.

Sentinel surveillance for influenza among severe acute respiratory infection and acute febrile illness inpatients at three hospitals in Ghana.

Jones AH, Ampofo W, Akuffo R, Doman B, Duplessis C, Amankwa JA, Sarpong C, Sagoe K, Agbenohevi P, Puplampu N, Armah G, Koram KA, Nyarko EO, Bel-Nono S, Dueger EL.

Influenza Other Respir Viruses. 2016 Sep;10(5):367-74. doi: 10.1111/irv.12397. Epub 2016 Jun 30.

24.

Within-host competition and drug resistance in the human malaria parasite Plasmodium falciparum.

Bushman M, Morton L, Duah N, Quashie N, Abuaku B, Koram KA, Dimbu PR, Plucinski M, Gutman J, Lyaruu P, Kachur SP, de Roode JC, Udhayakumar V.

Proc Biol Sci. 2016 Mar 16;283(1826):20153038. doi: 10.1098/rspb.2015.3038.

25.

Antitrypanosomal Activities and Mechanisms of Action of Novel Tetracyclic Iridoids from Morinda lucida Benth.

Kwofie KD, Tung NH, Suzuki-Ohashi M, Amoa-Bosompem M, Adegle R, Sakyiamah MM, Ayertey F, Owusu KB, Tuffour I, Atchoglo P, Frempong KK, Anyan WK, Uto T, Morinaga O, Yamashita T, Aboagye F, Appiah AA, Appiah-Opong R, Nyarko AK, Yamaguchi Y, Edoh D, Koram KA, Yamaoka S, Boakye DA, Ohta N, Shoyama Y, Ayi I.

Antimicrob Agents Chemother. 2016 May 23;60(6):3283-90. doi: 10.1128/AAC.01916-15. Print 2016 Jun.

26.

Measurement of ex vivo ELISpot interferon-gamma recall responses to Plasmodium falciparum AMA1 and CSP in Ghanaian adults with natural exposure to malaria.

Ganeshan H, Kusi KA, Anum D, Hollingdale MR, Peters B, Kim Y, Tetteh JK, Ofori MF, Gyan BA, Koram KA, Huang J, Belmonte M, Banania JG, Dodoo D, Villasante E, Sedegah M.

Malar J. 2016 Feb 1;15:55. doi: 10.1186/s12936-016-1098-8.

27.

Clonal types of Toxoplasma gondii among immune compromised and immune competent individuals in Accra, Ghana.

Ayi I, Kwofie KD, Blay EA, Osei JH, Frempong KK, Koku R, Ghansah A, Lartey M, Suzuki T, Boakye DA, Koram KA, Ohta N.

Parasitol Int. 2016 Jun;65(3):238-44. doi: 10.1016/j.parint.2016.01.004. Epub 2016 Jan 8.

PMID:
26775819
28.

Glucose-6-phosphate dehydrogenase deficiency and the risk of malaria and other diseases in children in Kenya: a case-control and a cohort study.

Uyoga S, Ndila CM, Macharia AW, Nyutu G, Shah S, Peshu N, Clarke GM, Kwiatkowski DP, Rockett KA, Williams TN; MalariaGEN Consortium.

Lancet Haematol. 2015 Oct;2(10):e437-44. doi: 10.1016/S2352-3026(15)00152-0. Epub 2015 Sep 22.

29.

Measuring regional and district variations in the incidence of pregnancy-induced hypertension in Ghana: challenges, opportunities and implications for maternal and newborn health policy and programmes.

Antwi E, Klipstein-Grobusch K, Quansah Asare G, Koram KA, Grobbee D, Agyepong IA.

Trop Med Int Health. 2016 Jan;21(1):93-100. doi: 10.1111/tmi.12626. Epub 2015 Nov 16.

30.

A novel locus of resistance to severe malaria in a region of ancient balancing selection.

Malaria Genomic Epidemiology Network, Band G, Rockett KA, Spencer CC, Kwiatkowski DP.

Nature. 2015 Oct 8;526(7572):253-7. doi: 10.1038/nature15390. Epub 2015 Sep 30.

31.

Serological evidence of vector and parasite exposure in Southern Ghana: the dynamics of malaria transmission intensity.

Badu K, Gyan B, Appawu M, Mensah D, Dodoo D, Yan G, Drakeley C, Zhou G, Owusu-Dabo E, Koram KA.

Parasit Vectors. 2015 Apr 28;8:251. doi: 10.1186/s13071-015-0861-y.

32.

Measuring naturally acquired ex vivo IFN-γ responses to Plasmodium falciparum cell-traversal protein for ookinetes and sporozoites (CelTOS) in Ghanaian adults.

Anum D, Kusi KA, Ganeshan H, Hollingdale MR, Ofori MF, Koram KA, Gyan BA, Adu-Amankwah S, Badji E, Huang J, Belmonte M, Banania GJ, Kwofie TB, Villasante E, Dodoo D, Sedegah M.

Malar J. 2015 Jan 21;14:20. doi: 10.1186/s12936-014-0539-5.

33.

Reappraisal of known malaria resistance loci in a large multicenter study.

Malaria Genomic Epidemiology Network; Malaria Genomic Epidemiology Network.

Nat Genet. 2014 Nov;46(11):1197-204. doi: 10.1038/ng.3107. Epub 2014 Sep 28.

34.

Anti-trypanosomal activity of diarylheptanoids isolated from the bark of Alnus japonica.

Tung NH, Suzuki M, Uto T, Morinaga O, Kwofie KD, Ammah N, Koram KA, Aboagye F, Edoh D, Yamashita T, Yamaguchi Y, Setsu T, Yamaoka S, Ohta N, Shoyama Y.

Am J Chin Med. 2014;42(5):1245-60. doi: 10.1142/S0192415X14500785. Epub 2014 Sep 1.

PMID:
25178281
35.

Dynamics of the antibody response to Plasmodium falciparum infection in African children.

White MT, Griffin JT, Akpogheneta O, Conway DJ, Koram KA, Riley EM, Ghani AC.

J Infect Dis. 2014 Oct 1;210(7):1115-22. doi: 10.1093/infdis/jiu219. Epub 2014 Apr 8.

PMID:
24719471
36.

Anti-sporozoite antibodies as alternative markers for malaria transmission intensity estimation.

Kusi KA, Bosomprah S, Dodoo D, Kyei-Baafour E, Dickson EK, Mensah D, Angov E, Dutta S, Sedegah M, Koram KA.

Malar J. 2014 Mar 17;13:103. doi: 10.1186/1475-2875-13-103.

37.

Patterns of cardiovascular disease mortality in Ghana: a 5-year review of autopsy cases at Korle-Bu Teaching Hospital.

Sanuade OA, Anarfi JK, Aikins Ad, Koram KA.

Ethn Dis. 2014 Winter;24(1):55-9.

PMID:
24620449
38.

Biochemical and hematologic parameters for children in the middle belt of Ghana.

Dosoo DK, Asante KP, Kayan K, Adu-Gyasi D, Osei-Kwakye K, Mahama E, Danso S, Amenga-Etego S, Bilson P, Koram KA, Owusu-Agyei S.

Am J Trop Med Hyg. 2014 Apr;90(4):767-73. doi: 10.4269/ajtmh.13-0098. Epub 2014 Mar 3.

39.

A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs.

Quashie NB, Duah NO, Abuaku B, Quaye L, Ayanful-Torgby R, Akwoviah GA, Kweku M, Johnson JD, Lucchi NW, Udhayakumar V, Duplessis C, Kronmann KC, Koram KA.

Malar J. 2013 Dec 17;12:450. doi: 10.1186/1475-2875-12-450.

40.

Co-evolution of human leukocyte antigen (HLA) class I ligands with killer-cell immunoglobulin-like receptors (KIR) in a genetically diverse population of sub-Saharan Africans.

Norman PJ, Hollenbach JA, Nemat-Gorgani N, Guethlein LA, Hilton HG, Pando MJ, Koram KA, Riley EM, Abi-Rached L, Parham P.

PLoS Genet. 2013 Oct;9(10):e1003938. doi: 10.1371/journal.pgen.1003938. Epub 2013 Oct 31.

41.

Increased pfmdr1 gene copy number and the decline in pfcrt and pfmdr1 resistance alleles in Ghanaian Plasmodium falciparum isolates after the change of anti-malarial drug treatment policy.

Duah NO, Matrevi SA, de Souza DK, Binnah DD, Tamakloe MM, Opoku VS, Onwona CO, Narh CA, Quashie NB, Abuaku B, Duplessis C, Kronmann KC, Koram KA.

Malar J. 2013 Oct 30;12:377. doi: 10.1186/1475-2875-12-377.

42.

Impact of treating young children with antimalarials with or without antibiotics on morbidity: a cluster-randomized controlled trial in Ghana.

Chinbuah MA, Adjuik M, Cobelens F, Koram KA, Abbey M, Gyapong M, Kager PA, Gyapong JO.

Int Health. 2013 Sep;5(3):228-35. doi: 10.1093/inthealth/iht021.

PMID:
24030274
43.

Surveillance of molecular markers of Plasmodium falciparum resistance to sulphadoxine-pyrimethamine 5 years after the change of malaria treatment policy in Ghana.

Duah NO, Quashie NB, Abuaku BK, Sebeny PJ, Kronmann KC, Koram KA.

Am J Trop Med Hyg. 2012 Dec;87(6):996-1003. doi: 10.4269/ajtmh.2012.12-0202. Epub 2012 Oct 8.

44.

Haematological and biochemical reference values for healthy adults in the middle belt of Ghana.

Dosoo DK, Kayan K, Adu-Gyasi D, Kwara E, Ocran J, Osei-Kwakye K, Mahama E, Amenga-Etego S, Bilson P, Asante KP, Koram KA, Owusu-Agyei S.

PLoS One. 2012;7(4):e36308. doi: 10.1371/journal.pone.0036308. Epub 2012 Apr 27.

45.

Haplotype analyses of haemoglobin C and haemoglobin S and the dynamics of the evolutionary response to malaria in Kassena-Nankana District of Ghana.

Ghansah A, Rockett KA, Clark TG, Wilson MD, Koram KA, Oduro AR, Amenga-Etego L, Anyorigiya T, Hodgson A, Milligan P, Rogers WO, Kwiatkowski DP.

PLoS One. 2012;7(4):e34565. doi: 10.1371/journal.pone.0034565. Epub 2012 Apr 10.

46.

Antiplasmodial activity of extracts of Tridax procumbens and Phyllanthus amarus in in vitro Plasmodium falciparum culture systems.

Appiah-Opong R, Nyarko AK, Dodoo D, Gyang FN, Koram KA, Ayisi NK.

Ghana Med J. 2011 Dec;45(4):143-50.

47.

Antibodies to Plasmodium falciparum antigens and the risk of clinical malaria in endemic populations.

Koram KA.

Expert Rev Anti Infect Ther. 2011 Nov;9(11):987-91. doi: 10.1586/eri.11.128.

PMID:
22029518
48.

Measuring naturally acquired immune responses to candidate malaria vaccine antigens in Ghanaian adults.

Dodoo D, Hollingdale MR, Anum D, Koram KA, Gyan B, Akanmori BD, Ocran J, Adu-Amankwah S, Geneshan H, Abot E, Legano J, Banania G, Sayo R, Brambilla D, Kumar S, Doolan DL, Rogers WO, Epstein J, Richie TL, Sedegah M.

Malar J. 2011 Jun 20;10:168. doi: 10.1186/1475-2875-10-168.

49.

Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana.

Ahorlu CK, Koram KA, Seake-Kwawu A, Weiss MG.

Malar J. 2011 May 15;10:127. doi: 10.1186/1475-2875-10-127.

50.

Antibody levels to multiple malaria vaccine candidate antigens in relation to clinical malaria episodes in children in the Kasena-Nankana district of Northern Ghana.

Dodoo D, Atuguba F, Bosomprah S, Ansah NA, Ansah P, Lamptey H, Egyir B, Oduro AR, Gyan B, Hodgson A, Koram KA.

Malar J. 2011 May 1;10:108. doi: 10.1186/1475-2875-10-108.

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