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Items: 20

1.

Pediatric high-grade glioma resources from the Children's Brain Tumor Tissue Consortium.

Ijaz H, Koptyra M, Gaonkar KS, Rokita JL, Baubet VP, Tauhid L, Zhu Y, Brown M, Lopez G, Zhang B, Diskin SJ, Vaksman Z; Children’s Brain Tumor Tissue Consortium, Mason JL, Appert E, Lilly J, Lulla R, De Raedt T, Heath AP, Felmeister A, Raman P, Nazarian J, Santi MR, Storm PB, Resnick A, Waanders AJ, Cole KA.

Neuro Oncol. 2020 Jan 11;22(1):163-165. doi: 10.1093/neuonc/noz192. No abstract available.

2.

Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL).

Park T, Koptyra M, Curran T.

J Biol Chem. 2016 Dec 16;291(51):26273-26290. Epub 2016 Nov 2.

3.

Normal ABL1 is a tumor suppressor and therapeutic target in human and mouse leukemias expressing oncogenic ABL1 kinases.

Dasgupta Y, Koptyra M, Hoser G, Kantekure K, Roy D, Gornicka B, Nieborowska-Skorska M, Bolton-Gillespie E, Cerny-Reiterer S, Müschen M, Valent P, Wasik MA, Richardson C, Hantschel O, van der Kuip H, Stoklosa T, Skorski T.

Blood. 2016 Apr 28;127(17):2131-43. doi: 10.1182/blood-2015-11-681171. Epub 2016 Feb 10.

4.

Crk and CrkL are required for cell transformation by v-fos and v-ras.

Koptyra M, Park TJ, Curran T.

Mol Carcinog. 2016 Jan;55(1):97-104. doi: 10.1002/mc.22262. Epub 2015 Jan 3.

PMID:
25557916
5.

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.

Hoang DT, Gu L, Liao Z, Shen F, Talati PG, Koptyra M, Tan SH, Ellsworth E, Gupta S, Montie H, Dagvadorj A, Savolainen S, Leiby B, Mirtti T, Merry DE, Nevalainen MT.

Mol Cancer Ther. 2015 Mar;14(3):713-26. doi: 10.1158/1535-7163.MCT-14-0819. Epub 2014 Dec 31.

6.

Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells.

Bolton-Gillespie E, Schemionek M, Klein HU, Flis S, Hoser G, Lange T, Nieborowska-Skorska M, Maier J, Kerstiens L, Koptyra M, Müller MC, Modi H, Stoklosa T, Seferynska I, Bhatia R, Holyoake TL, Koschmieder S, Skorski T.

Blood. 2013 May 16;121(20):4175-83. doi: 10.1182/blood-2012-11-466938. Epub 2013 Mar 29.

7.

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors.

Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Bolton E, Holyoake TL, Eaves CJ, Cerny-Reiterer S, Valent P, Hochhaus A, Hughes TP, van der Kuip H, Sattler M, Wiktor-Jedrzejczak W, Richardson C, Dorrance A, Stoklosa T, Williams DA, Skorski T.

Blood. 2012 May 3;119(18):4253-63. doi: 10.1182/blood-2011-10-385658. Epub 2012 Mar 12.

8.

Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.

Koptyra M, Gupta S, Talati P, Nevalainen MT.

Int J Biochem Cell Biol. 2011 Oct;43(10):1417-21. doi: 10.1016/j.biocel.2011.06.007. Epub 2011 Jun 17. Review.

9.

Imatinib sensitivity in BCR-ABL1-positive chronic myeloid leukemia cells is regulated by the remaining normal ABL1 allele.

Virgili A, Koptyra M, Dasgupta Y, Glodkowska-Mrowka E, Stoklosa T, Nacheva EP, Skorski T.

Cancer Res. 2011 Aug 15;71(16):5381-6. doi: 10.1158/0008-5472.CAN-11-0068. Epub 2011 Jun 21.

10.

Monoubiquitinated Fanconi anemia D2 (FANCD2-Ub) is required for BCR-ABL1 kinase-induced leukemogenesis.

Koptyra M, Stoklosa T, Hoser G, Glodkowska-Mrowka E, Seferynska I, Klejman A, Blasiak J, Skorski T.

Leukemia. 2011 Aug;25(8):1259-67. doi: 10.1038/leu.2011.91. Epub 2011 Apr 26.

11.

BCR/ABL and other kinases from chronic myeloproliferative disorders stimulate single-strand annealing, an unfaithful DNA double-strand break repair.

Cramer K, Nieborowska-Skorska M, Koptyra M, Slupianek A, Penserga ET, Eaves CJ, Aulitzky W, Skorski T.

Cancer Res. 2008 Sep 1;68(17):6884-8. doi: 10.1158/0008-5472.CAN-08-1101.

12.

BCR/ABL inhibits mismatch repair to protect from apoptosis and induce point mutations.

Stoklosa T, Poplawski T, Koptyra M, Nieborowska-Skorska M, Basak G, Slupianek A, Rayevskaya M, Seferynska I, Herrera L, Blasiak J, Skorski T.

Cancer Res. 2008 Apr 15;68(8):2576-80. doi: 10.1158/0008-5472.CAN-07-6858.

13.

BCR/ABL promotes accumulation of chromosomal aberrations induced by oxidative and genotoxic stress.

Koptyra M, Cramer K, Slupianek A, Richardson C, Skorski T.

Leukemia. 2008 Oct;22(10):1969-72. doi: 10.1038/leu.2008.78. Epub 2008 Apr 10. No abstract available.

14.

ATR-Chk1 axis protects BCR/ABL leukemia cells from the lethal effect of DNA double-strand breaks.

Nieborowska-Skorska M, Stoklosa T, Datta M, Czechowska A, Rink L, Slupianek A, Koptyra M, Seferynska I, Krszyna K, Blasiak J, Skorski T.

Cell Cycle. 2006 May;5(9):994-1000. Epub 2006 May 1.

PMID:
16687921
15.

IRS-1-Rad51 nuclear interaction sensitizes JCV T-antigen positive medulloblastoma cells to genotoxic treatment.

Trojanek J, Ho T, Croul S, Wang JY, Chintapalli J, Koptyra M, Giordano A, Khalili K, Reiss K.

Int J Cancer. 2006 Aug 1;119(3):539-48.

16.

BCR/ABL kinase induces self-mutagenesis via reactive oxygen species to encode imatinib resistance.

Koptyra M, Falinski R, Nowicki MO, Stoklosa T, Majsterek I, Nieborowska-Skorska M, Blasiak J, Skorski T.

Blood. 2006 Jul 1;108(1):319-27. Epub 2006 Mar 9.

17.

BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells.

Slupianek A, Nowicki MO, Koptyra M, Skorski T.

DNA Repair (Amst). 2006 Feb 3;5(2):243-50. Epub 2005 Nov 16.

18.

BLM helicase is activated in BCR/ABL leukemia cells to modulate responses to cisplatin.

Slupianek A, Gurdek E, Koptyra M, Nowicki MO, Siddiqui KM, Groden J, Skorski T.

Oncogene. 2005 Jun 2;24(24):3914-22.

PMID:
15750625
19.

BCR/ABL recruits p53 tumor suppressor protein to induce drug resistance.

Stoklosa T, Slupianek A, Datta M, Nieborowska-Skorska M, Nowicki MO, Koptyra M, Skorski T.

Cell Cycle. 2004 Nov;3(11):1463-72. Epub 2004 Nov 10.

PMID:
15492510
20.

BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks.

Nowicki MO, Falinski R, Koptyra M, Slupianek A, Stoklosa T, Gloc E, Nieborowska-Skorska M, Blasiak J, Skorski T.

Blood. 2004 Dec 1;104(12):3746-53. Epub 2004 Aug 10.

PMID:
15304390

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