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Items: 1 to 50 of 99

1.

Ginsenoside metabolite 20(S)-protopanaxatriol from Panax ginseng attenuates inflammation-mediated NLRP3 inflammasome activation.

Jiang J, Sun X, Akther M, Lian ML, Quan LH, Koppula S, Han JH, Kopalli SR, Kang TB, Lee KH.

J Ethnopharmacol. 2020 Jan 10;251:112564. doi: 10.1016/j.jep.2020.112564. [Epub ahead of print]

PMID:
31926987
2.

A systematic review on hepatoprotective activity of quercetin against various drugs and toxic agents: Evidence from preclinical studies.

Pingili RB, Challa SR, Pawar AK, Toleti V, Kodali T, Koppula S.

Phytother Res. 2020 Jan;34(1):5-32. doi: 10.1002/ptr.6503. Epub 2019 Oct 15. Review.

PMID:
31617262
3.

A comprehensive review on hepatoprotective and nephroprotective activities of chrysin against various drugs and toxic agents.

Pingili RB, Pawar AK, Challa SR, Kodali T, Koppula S, Toleti V.

Chem Biol Interact. 2019 Aug 1;308:51-60. doi: 10.1016/j.cbi.2019.05.010. Epub 2019 May 11. Review.

PMID:
31085170
4.

Anti-hepatofibrosis effect of Allium senescens in activated hepatic stellate cells and thioacetamide-induced fibrosis rat model.

Shin GM, Koppula S, Chae YJ, Kim HS, Lee JD, Kim MK, Song M.

Pharm Biol. 2018 Dec;56(1):632-642. doi: 10.1080/13880209.2018.1529801.

5.

Cordycepin, an Active Constituent of Nutrient Powerhouse and Potential Medicinal Mushroom Cordyceps militaris Linn., Ameliorates Age-Related Testicular Dysfunction in Rats.

Kopalli SR, Cha KM, Lee SH, Hwang SY, Lee YJ, Koppula S, Kim SK.

Nutrients. 2019 Apr 23;11(4). pii: E906. doi: 10.3390/nu11040906.

6.

Association of Physicians' Self-Compassion with Work Engagement, Exhaustion, and Professional Life Satisfaction.

Babenko O, Mosewich AD, Lee A, Koppula S.

Med Sci (Basel). 2019 Feb 12;7(2). pii: E29. doi: 10.3390/medsci7020029.

8.

Identification and Characterization of NTB451 as a Potential Inhibitor of Necroptosis.

In EJ, Lee Y, Koppula S, Kim TY, Han JH, Lee KH, Kang TB.

Molecules. 2018 Nov 5;23(11). pii: E2884. doi: 10.3390/molecules23112884.

9.

Physicians as Teachers and Lifelong Learners.

Ding M, Babenko O, Koppula S, Oswald A, White J.

J Contin Educ Health Prof. 2019 Winter;39(1):2-6. doi: 10.1097/CEH.0000000000000228.

PMID:
30394937
10.

Novel Small Molecule Inhibitors of Programmed Cell Death (PD)-1, and its Ligand, PD-L1 in Cancer Immunotherapy: A Review Update of Patent Literature.

Kopalli SR, Kang TB, Lee KH, Koppula S.

Recent Pat Anticancer Drug Discov. 2019;14(2):100-112. doi: 10.2174/1574892813666181029142812.

PMID:
30370857
11.

Fermentation-Mediated Enhancement of Ginseng's Anti-Allergic Activity against IgE-Mediated Passive Cutaneous Anaphylaxis In Vivo and In Vitro.

Hwang SW, Sun X, Han JH, Kim TY, Koppula S, Kang TB, Hwang JK, Lee KH.

J Microbiol Biotechnol. 2018 Oct 28;28(10):1626-1634. doi: 10.4014/jmb.1807.07057.

12.

Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation.

Kwak SB, Koppula S, In EJ, Sun X, Kim YK, Kim MK, Lee KH, Kang TB.

Mediators Inflamm. 2018 Mar 4;2018:6054069. doi: 10.1155/2018/6054069. eCollection 2018.

13.

Inhibitory Effect and Mechanism of Arctium lappa Extract on NLRP3 Inflammasome Activation.

Kim YK, Koppula S, Shim DW, In EJ, Kwak SB, Kim MK, Yu SH, Lee KH, Kang TB.

Evid Based Complement Alternat Med. 2018 Jan 18;2018:6346734. doi: 10.1155/2018/6346734. eCollection 2018.

14.

Eucalyptus globulus Inhibits Inflammasome-Activated Pro-Inflammatory Responses and Ameliorate Monosodium Urate-Induced Peritonitis in Murine Experimental Model.

Ji YE, Sun X, Kim MK, Li WY, Lee SW, Koppula S, Yu SH, Kim HB, Kang TB, Lee KH.

Am J Chin Med. 2018;46(2):423-433. doi: 10.1142/S0192415X18500210. Epub 2018 Feb 12.

PMID:
29433388
15.

Anti-fibrotic effects of Orostachys japonicus A. Berger (Crassulaceae) on hepatic stellate cells and thioacetamide-induced fibrosis in rats.

Koppula S, Yum MJ, Kim JS, Shin GM, Chae YJ, Yoon T, Chun CS, Lee JD, Song M.

Nutr Res Pract. 2017 Dec;11(6):470-478. doi: 10.4162/nrp.2017.11.6.470. Epub 2017 Nov 2.

16.

Actinidia arguta extract attenuates inflammasome activation: Potential involvement in NLRP3 ubiquitination.

Heo KH, Sun X, Shim DW, Kim MK, Koppula S, Yu SH, Kim HB, Kim TJ, Kang TB, Lee KH.

J Ethnopharmacol. 2018 Mar 1;213:159-165. doi: 10.1016/j.jep.2017.11.023. Epub 2017 Nov 21.

PMID:
29174375
17.

BOT-4-one attenuates NLRP3 inflammasome activation: NLRP3 alkylation leading to the regulation of its ATPase activity and ubiquitination.

Shim DW, Shin WY, Yu SH, Kim BH, Ye SK, Koppula S, Won HS, Kang TB, Lee KH.

Sci Rep. 2017 Nov 8;7(1):15020. doi: 10.1038/s41598-017-15314-8.

18.

Preparing teachers for competency-based medical education: Fundamental teaching activities.

Walsh A, Koppula S, Antao V, Bethune C, Cameron S, Cavett T, Clavet D, Dove M.

Med Teach. 2018 Jan;40(1):80-85. doi: 10.1080/0142159X.2017.1394998. Epub 2017 Nov 7.

PMID:
29113520
19.

NLRP3 Inflammasome Activation Inhibitors in Inflammation-Associated Cancer Immunotherapy: An Update on the Recent Patents.

Kopalli SR, Kang TB, Lee KH, Koppula S.

Recent Pat Anticancer Drug Discov. 2018;13(1):106-117. doi: 10.2174/1574892812666171027102627. Review.

PMID:
29076433
20.

Exercer un leadership de votre position d’éducateur: Le rôle du leader pédagogique dans le Référentiel des activités pédagogiques fondamentales.

Antao V, Cavett T, Walsh A, Bethune C, Cameron S, Clavet D, Dove M, Koppula S.

Can Fam Physician. 2017 Oct;63(10):e444-e448. French. No abstract available.

PMID:
29025822
Free PMC Article
21.

Leading from where you teach: Educational leader role within the Fundamental Teaching Activities Framework.

Antao V, Cavett T, Walsh A, Bethune C, Cameron S, Clavet D, Dove M, Koppula S.

Can Fam Physician. 2017 Oct;63(10):808-812. No abstract available.

22.

Lifelong learning along the education and career continuum: meta-analysis of studies in health professions.

Babenko O, Koppula S, Daniels L, Nadon L, Daniels V.

J Adv Med Educ Prof. 2017 Oct;5(4):157-163.

23.

Motivations for learning of family medicine residents trained in competency-based education.

Babenko O, Szafran O, Koppula S, Au L.

Educ Prim Care. 2018 Mar;29(2):86-93. doi: 10.1080/14739879.2017.1362666. Epub 2017 Aug 16.

PMID:
28812935
24.

Anti-fibrotic effects of Cuscuta chinensis with in vitro hepatic stellate cells and a thioacetamide-induced experimental rat model.

Kim JS, Koppula S, Yum MJ, Shin GM, Chae YJ, Hong SM, Lee JD, Song M.

Pharm Biol. 2017 Dec;55(1):1909-1919. doi: 10.1080/13880209.2017.1340965.

25.

Teaching outside the clinical setting: Twelve steps to feeling more comfortable and capable with any invitation to teach, based on the Fundamental Teaching Activities Framework.

Dove M, Bethune C, Antao V, Cameron S, Cavett T, Clavet D, Koppula S, Walsh A.

Can Fam Physician. 2017 Apr;63(4):329-332. No abstract available.

26.

Protective effects of Ampelopsis brevipedunculata against in vitro hepatic stellate cells system and thioacetamide-induced liver fibrosis rat model.

Yum MJ, Koppula S, Kim JS, Shin GM, Chae YJ, Yoon T, Chun CS, Lee JD, Song M.

Pharm Biol. 2017 Dec;55(1):1577-1585. doi: 10.1080/13880209.2017.1311928.

27.

Protective effects of Cinnamomum cassia (Lamaceae) against gout and septic responses via attenuation of inflammasome activation in experimental models.

Shin WY, Shim DW, Kim MK, Sun X, Koppula S, Yu SH, Kim HB, Kim TJ, Kang TB, Lee KH.

J Ethnopharmacol. 2017 Jun 9;205:173-177. doi: 10.1016/j.jep.2017.03.043. Epub 2017 Mar 24.

PMID:
28347828
28.

Corrigendum to "α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease" [Neuropharm 97 (2015) 46-57].

Kim BW, Koppula S, Kumar H, Park JY, Kim IW, More SV, Kim IS, Han SD, Kim SK, Yoon SH, Choi DK.

Neuropharmacology. 2017 Apr;116:444-445. doi: 10.1016/j.neuropharm.2017.02.023. Epub 2017 Mar 1. No abstract available.

PMID:
28259359
29.

Analysis of Epidermal Growth Factor Receptor Related Gene Expression Changes in a Cellular and Animal Model of Parkinson's Disease.

Kim IS, Koppula S, Park SY, Choi DK.

Int J Mol Sci. 2017 Feb 16;18(2). pii: E430. doi: 10.3390/ijms18020430.

30.

Risk of Acute Kidney Injury in Patients on Concomitant Vancomycin and Piperacillin-Tazobactam Compared to Those on Vancomycin and Cefepime.

Navalkele B, Pogue JM, Karino S, Nishan B, Salim M, Solanki S, Pervaiz A, Tashtoush N, Shaikh H, Koppula S, Koons J, Hussain T, Perry W, Evans R, Martin ET, Mynatt RP, Murray KP, Rybak MJ, Kaye KS.

Clin Infect Dis. 2017 Jan 15;64(2):116-123. doi: 10.1093/cid/ciw709. Epub 2016 Oct 20.

PMID:
27986669
31.

Engaging Patients and Clinicians in Establishing Research Priorities for Gestational Diabetes Mellitus.

Rees SE, Chadha R, Donovan LE, Guitard AL, Koppula S, Laupacis A, Simpson S, Johnson JA.

Can J Diabetes. 2017 Apr;41(2):156-163. doi: 10.1016/j.jcjd.2016.08.219. Epub 2016 Nov 21.

PMID:
27881298
32.

Necroptosis inhibitors as therapeutic targets in inflammation mediated disorders - a review of the current literature and patents.

Kopalli SR, Kang TB, Koppula S.

Expert Opin Ther Pat. 2016 Nov;26(11):1239-1256. Epub 2016 Sep 8. Review.

PMID:
27568917
33.

Juniperus rigida Sieb. extract inhibits inflammatory responses via attenuation of TRIF-dependent signaling and inflammasome activation.

Han JW, Shim DW, Shin WY, Kim MK, Shim EJ, Sun X, Koppula S, Kim TJ, Kang TB, Lee KH.

J Ethnopharmacol. 2016 Aug 22;190:91-9. doi: 10.1016/j.jep.2016.05.059. Epub 2016 May 31.

PMID:
27260408
34.

Epidemiology of Acute Kidney Injury among Patients Receiving Concomitant Vancomycin and Piperacillin-Tazobactam: Opportunities for Antimicrobial Stewardship.

Karino S, Kaye KS, Navalkele B, Nishan B, Salim M, Solanki S, Pervaiz A, Tashtoush N, Shaikh H, Koppula S, Martin ET, Mynatt RP, Murray KP, Rybak MJ, Pogue JM.

Antimicrob Agents Chemother. 2016 May 23;60(6):3743-50. doi: 10.1128/AAC.03011-15. Print 2016 Jun.

35.

Cichorium intybus Linn. Extract Prevents Type 2 Diabetes Through Inhibition of NLRP3 Inflammasome Activation.

Shim DW, Han JW, Ji YE, Shin WY, Koppula S, Kim MK, Kim TK, Park PJ, Kang TB, Lee KH.

J Med Food. 2016 Mar;19(3):310-7. doi: 10.1089/jmf.2015.3556.

PMID:
26987023
36.

Ginger for nausea and vomiting of pregnancy.

Lindblad AJ, Koppula S.

Can Fam Physician. 2016 Feb;62(2):145. Review.

37.

Rhus javanica Linn protects against hydrogen peroxide‑induced toxicity in human Chang liver cells via attenuation of oxidative stress and apoptosis signaling.

Yoon C, Koppula S, Yoo S, Yum M, Kim J, Lee J, Song M.

Mol Med Rep. 2016 Jan;13(1):1019-25. doi: 10.3892/mmr.2015.4603. Epub 2015 Nov 23.

PMID:
26648020
38.

Anti-inflammatory properties of Morus bombycis Koidzumi via inhibiting IFN-β signaling and NLRP3 inflammasome activation.

Oh NH, Han JW, Shim DW, Sim EJ, Koppula S, Kwak SB, Kim MK, Kim YK, Jiang J, Park PJ, Kang TB, Lee KH.

J Ethnopharmacol. 2015 Dec 24;176:424-8. doi: 10.1016/j.jep.2015.11.022. Epub 2015 Nov 10.

PMID:
26571084
39.

Transform a teaching moment into your own learning moment: Fundamental Teaching Activities Framework.

Clavet D, Antao V, Koppula S, Walsh A.

Can Fam Physician. 2015 Oct;61(10):e484-8, 913-7. English, French. No abstract available.

40.

Low concentrations of doxycycline attenuates FasL-induced apoptosis in HeLa cells.

Yoon JM, Koppula S, Huh SJ, Hur SJ, Kim CG.

Biol Res. 2015 Jul 24;48:38. doi: 10.1186/s40659-015-0025-8.

41.

α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease.

Kim BW, Koppula S, Kumar H, Park JY, Kim IW, More SV, Kim IS, Han SD, Kim SK, Yoon SH, Choi DK.

Neuropharmacology. 2015 Oct;97:46-57. doi: 10.1016/j.neuropharm.2015.04.037. Epub 2015 May 15. Erratum in: Neuropharmacology. 2017 Apr;116:444-445.

PMID:
25983275
42.

Anti-inflammatory effect of Impatiens textori Miq. extract via inhibition of NLRP3 inflammasome activation in in vitro and in vivo experimental models.

Sun X, Shim DW, Han JW, Shin WY, Sim EJ, Kim MK, Heo KH, Kim YK, Koppula S, Kim TJ, Kang TB, Lee KH.

J Ethnopharmacol. 2015 Jul 21;170:81-7. doi: 10.1016/j.jep.2015.05.001. Epub 2015 May 11.

PMID:
25975512
43.

Syneilesis palmata (Thunb.) Maxim. extract attenuates inflammatory responses via the regulation of TRIF-dependent signaling and inflammasome activation.

Han JW, Shim DW, Shim EJ, Kim MK, Shin YK, Kwak SB, Koppula S, Kim TJ, Kang TB, Lee KH.

J Ethnopharmacol. 2015 May 26;166:1-4. doi: 10.1016/j.jep.2015.02.056. Epub 2015 Mar 6.

PMID:
25747147
44.

A novel synthetic derivative of melatonin, 5-hydroxy-2'-isobutyl-streptochlorin (HIS), inhibits inflammatory responses via regulation of TRIF-dependent signaling and inflammasome activation.

Shim DW, Shin HJ, Han JW, Ji YE, Jang CH, Koppula S, Kang TB, Lee KH.

Toxicol Appl Pharmacol. 2015 Apr 15;284(2):227-35. doi: 10.1016/j.taap.2015.02.006. Epub 2015 Feb 14.

PMID:
25689174
45.

Integrated women's health program.

Koppula S.

Can Fam Physician. 2014 Dec;60(12):e593-600.

46.

Attenuation of inflammatory-mediated neurotoxicity by Saururus chinensis extract in LPS-induced BV-2 microglia cells via regulation of NF-κB signaling and anti-oxidant properties.

Kim BW, Koppula S, Park SY, Hwang JW, Park PJ, Lim JH, Choi DK.

BMC Complement Altern Med. 2014 Dec 16;14:502. doi: 10.1186/1472-6882-14-502.

47.

Attenuation of neuroinflammatory responses and behavioral deficits by Ligusticum officinale (Makino) Kitag in stimulated microglia and MPTP-induced mouse model of Parkinson's disease.

Kim BW, Koppula S, Park SY, Kim YS, Park PJ, Lim JH, Kim IS, Choi DK.

J Ethnopharmacol. 2015 Apr 22;164:388-97. doi: 10.1016/j.jep.2014.11.004. Epub 2014 Nov 11.

PMID:
25449453
48.

Pitfalls in dosing vancomycin.

Koppula S, Ruben S, Bangash F, Szerlip HM.

Am J Med Sci. 2015 Feb;349(2):137-9. doi: 10.1097/MAJ.0000000000000368.

PMID:
25437128
49.

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