Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 66

1.

Analysis of secondary care data to evaluate the clinical relevance of the drug-drug interaction between amlodipine and simvastatin.

Fuhrmann S, Koppen A, Seeling A, Knoth H, Schröder J.

Z Evid Fortbild Qual Gesundhwes. 2019 Jul 16. pii: S1865-9217(19)30079-0. doi: 10.1016/j.zefq.2019.06.003. [Epub ahead of print]

PMID:
31324418
2.

The APOE3-Leiden Heterozygous Glucokinase Knockout Mouse as Novel Translational Disease Model for Type 2 Diabetes, Dyslipidemia, and Diabetic Atherosclerosis.

Pouwer MG, Heinonen SE, Behrendt M, Andréasson AC, van Koppen A, Menke AL, Pieterman EJ, van den Hoek AM, Jukema JW, Leighton B, Jönsson-Rylander AC, Princen HMG.

J Diabetes Res. 2019 Feb 21;2019:9727952. doi: 10.1155/2019/9727952. eCollection 2019.

3.

Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice.

Morrison MC, Verschuren L, Salic K, Verheij J, Menke A, Wielinga PY, Iruarrizaga-Lejarreta M, Gole L, Yu WM, Turner S, Caspers MPM, Martínez-Arranz I, Pieterman E, Stoop R, van Koppen A, van den Hoek AM, Mato JM, Hanemaaijer R, Alonso C, Kleemann R.

Hepatol Commun. 2018 Oct 29;2(12):1513-1532. doi: 10.1002/hep4.1270. eCollection 2018 Dec.

4.

Profiling of 3696 Nuclear Receptor-Coregulator Interactions: A Resource for Biological and Clinical Discovery.

Broekema MF, Hollman DAA, Koppen A, van den Ham HJ, Melchers D, Pijnenburg D, Ruijtenbeek R, van Mil SWC, Houtman R, Kalkhoven E.

Endocrinology. 2018 Jun 1;159(6):2397-2407. doi: 10.1210/en.2018-00149.

PMID:
29718163
5.

Key Inflammatory Processes in Human NASH Are Reflected in Ldlr-/-.Leiden Mice: A Translational Gene Profiling Study.

Morrison MC, Kleemann R, van Koppen A, Hanemaaijer R, Verschuren L.

Front Physiol. 2018 Feb 23;9:132. doi: 10.3389/fphys.2018.00132. eCollection 2018.

6.

Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model.

van Koppen A, Verschuren L, van den Hoek AM, Verheij J, Morrison MC, Li K, Nagabukuro H, Costessi A, Caspers MPM, van den Broek TJ, Sagartz J, Kluft C, Beysen C, Emson C, van Gool AJ, Goldschmeding R, Stoop R, Bobeldijk-Pastorova I, Turner SM, Hanauer G, Hanemaaijer R.

Cell Mol Gastroenterol Hepatol. 2017 Oct 14;5(1):83-98.e10. doi: 10.1016/j.jcmgh.2017.10.001. eCollection 2018.

7.

[Treatment of paracetamol intoxication: taking into consideration dosage, route of administration, and risk factors].

Koppen A, van Riel AJHP, Nugteren-van Lonkhuyzen A, de Vries I.

Ned Tijdschr Geneeskd. 2017;161:D1644. Review. Dutch.

PMID:
29125075
8.

Variable cartilage degradation in mice with diet-induced metabolic dysfunction: food for thought.

Kozijn AE, Gierman LM, van der Ham F, Mulder P, Morrison MC, Kühnast S, van der Heijden RA, Stavro PM, van Koppen A, Pieterman EJ, van den Hoek AM, Kleemann R, Princen HMG, Mastbergen SC, Lafeber FPJG, Zuurmond AM, Bobeldijk I, Weinans H, Stoop R.

Osteoarthritis Cartilage. 2018 Jan;26(1):95-107. doi: 10.1016/j.joca.2017.10.010. Epub 2017 Oct 24.

9.

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Morrison MC, Yakala GK, Liang W, Wielinga PY, Salic K, van Koppen A, Tomar T, Kleemann R, Heeringa P, Kooistra T.

Sci Rep. 2017 Jun 6;7(1):2915. doi: 10.1038/s41598-017-02444-2.

10.

The centrosomal OFD1 protein interacts with the translation machinery and regulates the synthesis of specific targets.

Iaconis D, Monti M, Renda M, van Koppen A, Tammaro R, Chiaravalli M, Cozzolino F, Pignata P, Crina C, Pucci P, Boletta A, Belcastro V, Giles RH, Surace EM, Gallo S, Pende M, Franco B.

Sci Rep. 2017 Apr 27;7(1):1224. doi: 10.1038/s41598-017-01156-x.

11.

Is it really safe to withhold folinic acid when less than 1000 mg/m2 methotrexate is ingested?

Koppen A, Dijkman MA, Hunault CC, de Lange DW, de Vries I.

Clin Toxicol (Phila). 2017 Nov;55(9):1018. doi: 10.1080/15563650.2017.1307386. Epub 2017 Apr 26. No abstract available.

PMID:
28443374
12.

Targeting multiple pathways reduces renal and cardiac fibrosis in rats with subtotal nephrectomy followed by coronary ligation.

Oosterhuis NR, Bongartz LG, Verhaar MC, Cheng C, Xu YJ, van Koppen A, Cramer MJ, Goldschmeding R, Gaillard CA, Doevendans PA, Braam B, Joles JA.

Acta Physiol (Oxf). 2017 Jul;220(3):382-393. doi: 10.1111/apha.12829. Epub 2017 Feb 7.

PMID:
28168814
13.

Rapid hepatic clearance of full length CCN-2/CTGF: a putative role for LRP1-mediated endocytosis.

Gerritsen KG, Bovenschen N, Nguyen TQ, Sprengers D, Koeners MP, van Koppen AN, Joles JA, Goldschmeding R, Kok RJ.

J Cell Commun Signal. 2016 Dec;10(4):295-303. Epub 2016 Sep 19.

14.

Is a 1% Plasma Lipid Concentration Helpful to Treat the Intoxicated Patient?

Dijkman MA, Koppen A, Meulenbelt J.

Ann Emerg Med. 2016 Mar;67(3):418-9. doi: 10.1016/j.annemergmed.2015.11.003. No abstract available.

PMID:
26915555
15.

Arrhythmogenic Remodeling in Murine Models of Deoxycorticosterone Acetate-Salt-Induced and 5/6-Subtotal Nephrectomy-Salt-Induced Cardiorenal Disease.

Fontes MS, Papazova DA, van Koppen A, de Jong S, Korte SM, Bongartz LG, Nguyen TQ, Bierhuizen MF, de Boer TP, van Veen TA, Verhaar MC, Joles JA, van Rijen HV.

Cardiorenal Med. 2015 Jun;5(3):208-18. doi: 10.1159/000430475. Epub 2015 Jun 5.

16.

Ex vivo exposure of bone marrow from chronic kidney disease donor rats to pravastatin limits renal damage in recipient rats with chronic kidney disease.

van Koppen A, Papazova DA, Oosterhuis NR, Gremmels H, Giles RH, Fledderus JO, Joles JA, Verhaar MC.

Stem Cell Res Ther. 2015 Apr 15;6:63. doi: 10.1186/s13287-015-0064-7.

17.

Cell-based therapies for experimental chronic kidney disease: a systematic review and meta-analysis.

Papazova DA, Oosterhuis NR, Gremmels H, van Koppen A, Joles JA, Verhaar MC.

Dis Model Mech. 2015 Mar;8(3):281-93. doi: 10.1242/dmm.017699. Epub 2015 Jan 29. Review.

18.

Reply: To PMID 24930458.

Koppen A, van Riel A, de Vries I, Meulenbelt J.

Neth J Med. 2014 Oct;72(8):438. No abstract available.

19.

Recommendations for the paracetamol treatment nomogram and side effects of N-acetylcysteine.

Koppen A, van Riel A, de Vries I, Meulenbelt J.

Neth J Med. 2014 Jun;72(5):251-7. Review.

20.

Maintenance of hypertensive hemodynamics does not depend on ROS in established experimental chronic kidney disease.

Papazova DA, van Koppen A, Koeners MP, Bleys RL, Verhaar MC, Joles JA.

PLoS One. 2014 Feb 12;9(2):e88596. doi: 10.1371/journal.pone.0088596. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e99476.

21.

The relation between body iron stores and adipose tissue function in patients with manifest vascular disease.

Westerink J, Olijhoek JK, Koppen A, Faber DR, Kalkhoven E, Monajemi H, van Asbeck BS, van der Graaf Y, Visseren FL.

Eur J Clin Invest. 2013 Dec;43(12):1240-9. doi: 10.1111/eci.12165. Epub 2013 Sep 23.

PMID:
24245570
22.

Early adipogenesis is regulated through USP7-mediated deubiquitination of the histone acetyltransferase TIP60.

Gao Y, Koppen A, Rakhshandehroo M, Tasdelen I, van de Graaf SF, van Loosdregt J, van Beekum O, Hamers N, van Leenen D, Berkers CR, Berger R, Holstege FC, Coffer PJ, Brenkman AB, Ovaa H, Kalkhoven E.

Nat Commun. 2013;4:2656. doi: 10.1038/ncomms3656.

PMID:
24141283
23.

Impaired effect of relaxin on vasoconstrictor reactivity in spontaneous hypertensive rats.

van Drongelen J, van Koppen A, Pertijs J, Gooi JH, Sweep FC, Lotgering FK, Spaanderman ME, Smits P.

Peptides. 2013 Nov;49:41-8. doi: 10.1016/j.peptides.2013.08.020. Epub 2013 Sep 5.

PMID:
24012667
24.

5/6th nephrectomy in combination with high salt diet and nitric oxide synthase inhibition to induce chronic kidney disease in the Lewis rat.

van Koppen A, Verhaar MC, Bongartz LG, Joles JA.

J Vis Exp. 2013 Jul 3;(77):e50398. doi: 10.3791/50398.

25.

Pmch-deficiency in rats is associated with normal adipocyte differentiation and lower sympathetic adipose drive.

Mul JD, O'Duibhir E, Shrestha YB, Koppen A, Vargoviç P, Toonen PW, Zarebidaki E, Kvetnansky R, Kalkhoven E, Cuppen E, Bartness TJ.

PLoS One. 2013;8(3):e60214. doi: 10.1371/journal.pone.0060214. Epub 2013 Mar 26.

26.

Bone marrow cell therapy in hypertensive kidney disease: contribution to cardiac fibrosis?

van Koppen A, Joles JA, Verhaar MC.

J Hypertens. 2013 May;31(5):1052-4. doi: 10.1097/HJH.0b013e32835fdf87. No abstract available.

PMID:
23552031
27.

Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.

Alex S, Lange K, Amolo T, Grinstead JS, Haakonsson AK, Szalowska E, Koppen A, Mudde K, Haenen D, Al-Lahham S, Roelofsen H, Houtman R, van der Burg B, Mandrup S, Bonvin AM, Kalkhoven E, Müller M, Hooiveld GJ, Kersten S.

Mol Cell Biol. 2013 Apr;33(7):1303-16. doi: 10.1128/MCB.00858-12. Epub 2013 Jan 22.

28.

The serine/threonine phosphatase PPM1B (PP2Cβ) selectively modulates PPARγ activity.

Tasdelen I, van Beekum O, Gorbenko O, Fleskens V, van den Broek NJ, Koppen A, Hamers N, Berger R, Coffer PJ, Brenkman AB, Kalkhoven E.

Biochem J. 2013 Apr 1;451(1):45-53. doi: 10.1042/BJ20121113.

PMID:
23320500
29.

Healthy bone marrow cells reduce progression of kidney failure better than CKD bone marrow cells in rats with established chronic kidney disease.

van Koppen A, Joles JA, Bongartz LG, van den Brandt J, Reichardt HM, Goldschmeding R, Nguyen TQ, Verhaar MC.

Cell Transplant. 2012;21(10):2299-312. doi: 10.3727/096368912X636795.

PMID:
23231961
30.

Natural killer T cells in adipose tissue prevent insulin resistance.

Schipper HS, Rakhshandehroo M, van de Graaf SF, Venken K, Koppen A, Stienstra R, Prop S, Meerding J, Hamers N, Besra G, Boon L, Nieuwenhuis EE, Elewaut D, Prakken B, Kersten S, Boes M, Kalkhoven E.

J Clin Invest. 2012 Sep;122(9):3343-54. doi: 10.1172/JCI62739. Epub 2012 Aug 6.

31.

Human embryonic mesenchymal stem cell-derived conditioned medium rescues kidney function in rats with established chronic kidney disease.

van Koppen A, Joles JA, van Balkom BW, Lim SK, de Kleijn D, Giles RH, Verhaar MC.

PLoS One. 2012;7(6):e38746. doi: 10.1371/journal.pone.0038746. Epub 2012 Jun 19.

32.

A novel RNAi lethality rescue screen to identify regulators of adipogenesis.

van Beekum O, Gao Y, Berger R, Koppen A, Kalkhoven E.

PLoS One. 2012;7(6):e37680. doi: 10.1371/journal.pone.0037680. Epub 2012 Jun 5.

33.

Pref-1 preferentially inhibits heat production in brown adipose tissue.

Rakhshandehroo M, Koppen A, Kalkhoven E.

Biochem J. 2012 May 1;443(3):e3-5. doi: 10.1042/BJ20120382.

PMID:
22507130
34.

Impaired vascular responses to relaxin in diet-induced overweight female rats.

van Drongelen J, van Koppen A, Pertijs J, Gooi JH, Parry LJ, Sweep FC, Lotgering FK, Smits P, Spaanderman ME.

J Appl Physiol (1985). 2012 Mar;112(6):962-9. doi: 10.1152/japplphysiol.00470.2011. Epub 2011 Dec 15.

35.

Characterisation of non-obese diabetic patients with marked insulin resistance identifies a novel familial partial lipodystrophy-associated PPARγ mutation (Y151C).

Visser ME, Kropman E, Kranendonk ME, Koppen A, Hamers N, Stroes ES, Kalkhoven E, Monajemi H.

Diabetologia. 2011 Jul;54(7):1639-44. doi: 10.1007/s00125-011-2142-4. Epub 2011 Apr 9.

36.

Brown vs white adipocytes: the PPARgamma coregulator story.

Koppen A, Kalkhoven E.

FEBS Lett. 2010 Aug 4;584(15):3250-9. doi: 10.1016/j.febslet.2010.06.035. Epub 2010 Jun 30. Review.

37.

Epidermis-type lipoxygenase 3 regulates adipocyte differentiation and peroxisome proliferator-activated receptor gamma activity.

Hallenborg P, Jørgensen C, Petersen RK, Feddersen S, Araujo P, Markt P, Langer T, Furstenberger G, Krieg P, Koppen A, Kalkhoven E, Madsen L, Kristiansen K.

Mol Cell Biol. 2010 Aug;30(16):4077-91. doi: 10.1128/MCB.01806-08. Epub 2010 Jun 7.

38.

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver.

Sanderson LM, Degenhardt T, Koppen A, Kalkhoven E, Desvergne B, Müller M, Kersten S.

Mol Cell Biol. 2009 Dec;29(23):6257-67. doi: 10.1128/MCB.00370-09. Epub 2009 Oct 5. Erratum in: Mol Cell Biol. 2010 Oct;30(20):4977.

39.

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor.

Koppen A, Houtman R, Pijnenburg D, Jeninga EH, Ruijtenbeek R, Kalkhoven E.

Mol Cell Proteomics. 2009 Oct;8(10):2212-26. doi: 10.1074/mcp.M900209-MCP200. Epub 2009 Jul 10.

40.

Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics.

Sanderson LM, de Groot PJ, Hooiveld GJ, Koppen A, Kalkhoven E, Müller M, Kersten S.

PLoS One. 2008 Feb 27;3(2):e1681. doi: 10.1371/journal.pone.0001681.

41.

A site-related suitability analysis for the production of biomass as a contribution to sustainable regional land-use.

Förster M, Helms Y, Herberg A, Köppen A, Kunzmann K, Radtke D, Ross L, Itzerott S.

Environ Manage. 2008 Apr;41(4):584-98. doi: 10.1007/s00267-008-9068-8.

PMID:
18228088
42.

Dickkopf-3 expression is a marker for neuroblastic tumor maturation and is down-regulated by MYCN.

Koppen A, Ait-Aissa R, Koster J, Øra I, Bras J, van Sluis PG, Caron H, Versteeg R, Valentijn LJ.

Int J Cancer. 2008 Apr 1;122(7):1455-64.

43.

Direct regulation of the minichromosome maintenance complex by MYCN in neuroblastoma.

Koppen A, Ait-Aissa R, Koster J, van Sluis PG, Ora I, Caron HN, Volckmann R, Versteeg R, Valentijn LJ.

Eur J Cancer. 2007 Nov;43(16):2413-22. Epub 2007 Sep 10.

PMID:
17826980
44.

Dickkopf-1 is down-regulated by MYCN and inhibits neuroblastoma cell proliferation.

Koppen A, Ait-Aissa R, Hopman S, Koster J, Haneveld F, Versteeg R, Valentijn LJ.

Cancer Lett. 2007 Oct 28;256(2):218-28. Epub 2007 Jul 23.

PMID:
17643814
45.

Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia.

Heemskerk S, van Koppen A, van den Broek L, Poelen GJ, Wouterse AC, Dijkman HB, Russel FG, Masereeuw R.

Pflugers Arch. 2007 May;454(2):321-34. Epub 2007 Feb 7.

46.

Inhibition of a new differentiation pathway in neuroblastoma by copy number defects of N-myc, Cdc42, and nm23 genes.

Valentijn LJ, Koppen A, van Asperen R, Root HA, Haneveld F, Versteeg R.

Cancer Res. 2005 Apr 15;65(8):3136-45.

47.

Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus.

Manders EM, Visser AE, Koppen A, de Leeuw WC, van Liere R, Brakenhoff GJ, van Driel R.

Chromosome Res. 2003;11(5):537-47.

PMID:
12971728
48.

Regulation of free choline in rat brain: dietary and pharmacological manipulations.

Klein J, Köppen A, Löffelholz K.

Neurochem Int. 1998 May-Jun;32(5-6):479-85.

PMID:
9676747
49.

Acetylcholine release and choline availability in rat hippocampus: effects of exogenous choline and nicotinamide.

Köppen A, Klein J, Erb C, Löffelholz K.

J Pharmacol Exp Ther. 1997 Sep;282(3):1139-45.

PMID:
9316819
50.

Modulation of hippocampal acetylcholine release after fimbria-fornix lesions and septal transplantation in rats.

Erb C, Klein J, Köppen A, Löffelholz K, Jeltsch H, Cassel JC.

Neurosci Lett. 1997 Aug 1;231(1):5-8.

PMID:
9280154

Supplemental Content

Loading ...
Support Center