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Items: 1 to 50 of 285

1.

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA.

Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.

PMID:
31209336
2.

Prenatal Particulate Air Pollution and DNA Methylation in Newborns: An Epigenome-Wide Meta-Analysis.

Gruzieva O, Xu CJ, Yousefi P, Relton C, Merid SK, Breton CV, Gao L, Volk HE, Feinberg JI, Ladd-Acosta C, Bakulski K, Auffray C, Lemonnier N, Plusquin M, Ghantous A, Herceg Z, Nawrot TS, Pizzi C, Richiardi L, Rusconi F, Vineis P, Kogevinas M, Felix JF, Duijts L, den Dekker HT, Jaddoe VWV, Ruiz JL, Bustamante M, Antó JM, Sunyer J, Vrijheid M, Gutzkow KB, Grazuleviciene R, Hernandez-Ferrer C, Annesi-Maesano I, Lepeule J, Bousquet J, Bergström A, Kull I, Söderhäll C, Kere J, Gehring U, Brunekreef B, Just AC, Wright RJ, Peng C, Gold DR, Kloog I, DeMeo DL, Pershagen G, Koppelman GH, London SJ, Baccarelli AA, Melén E.

Environ Health Perspect. 2019 May;127(5):57012. doi: 10.1289/EHP4522. Epub 2019 May 31.

3.

Genetic risk scores do not improve asthma prediction in childhood.

Dijk FN, Folkersma C, Gruzieva O, Kumar A, Wijga AH, Gehring U, Kull I, Postma DS, Vonk JM, Melén E, Koppelman GH.

J Allergy Clin Immunol. 2019 May 27. pii: S0091-6749(19)30687-6. doi: 10.1016/j.jaci.2019.05.017. [Epub ahead of print] No abstract available.

PMID:
31145937
4.

Use of cleaning agents at home and respiratory and allergic symptoms in adolescents: The PIAMA birth cohort study.

Bukalasa JS, Brunekreef B, Koppelman GH, Vonk JM, Gehring U.

Environ Int. 2019 Jul;128:63-69. doi: 10.1016/j.envint.2019.03.049. Epub 2019 Apr 25.

5.

Pathway analysis of a genome-wide gene by air pollution interaction study in asthmatic children.

Ierodiakonou D, Coull BA, Zanobetti A, Postma DS, Boezen HM, Vonk JM, McKone EF, Schildcrout JS, Koppelman GH, Croteau-Chonka DC, Lumley T, Koutrakis P, Schwartz J, Gold DR, Weiss ST.

J Expo Sci Environ Epidemiol. 2019 Jun;29(4):539-547. doi: 10.1038/s41370-019-0136-3. Epub 2019 Apr 26.

PMID:
31028280
6.

Improvements in air quality: whose lungs benefit?

Gehring U, Koppelman GH.

Eur Respir J. 2019 Apr 25;53(4). pii: 1900365. doi: 10.1183/13993003.00365-2019. Print 2019 Apr. No abstract available.

PMID:
31023867
7.

Considerations in the use of different spirometers in epidemiological studies.

Milanzi EB, Koppelman GH, Oldenwening M, Augustijn S, Aalders-de Ruijter B, Farenhorst M, Vonk JM, Tewis M, Brunekreef B, Gehring U.

Environ Health. 2019 Apr 25;18(1):39. doi: 10.1186/s12940-019-0478-2.

8.

Meta-analysis of epigenome-wide association studies in neonates reveals widespread differential DNA methylation associated with birthweight.

Küpers LK, Monnereau C, Sharp GC, Yousefi P, Salas LA, Ghantous A, Page CM, Reese SE, Wilcox AJ, Czamara D, Starling AP, Novoloaca A, Lent S, Roy R, Hoyo C, Breton CV, Allard C, Just AC, Bakulski KM, Holloway JW, Everson TM, Xu CJ, Huang RC, van der Plaat DA, Wielscher M, Merid SK, Ullemar V, Rezwan FI, Lahti J, van Dongen J, Langie SAS, Richardson TG, Magnus MC, Nohr EA, Xu Z, Duijts L, Zhao S, Zhang W, Plusquin M, DeMeo DL, Solomon O, Heimovaara JH, Jima DD, Gao L, Bustamante M, Perron P, Wright RO, Hertz-Picciotto I, Zhang H, Karagas MR, Gehring U, Marsit CJ, Beilin LJ, Vonk JM, Jarvelin MR, Bergström A, Örtqvist AK, Ewart S, Villa PM, Moore SE, Willemsen G, Standaert ARL, Håberg SE, Sørensen TIA, Taylor JA, Räikkönen K, Yang IV, Kechris K, Nawrot TS, Silver MJ, Gong YY, Richiardi L, Kogevinas M, Litonjua AA, Eskenazi B, Huen K, Mbarek H, Maguire RL, Dwyer T, Vrijheid M, Bouchard L, Baccarelli AA, Croen LA, Karmaus W, Anderson D, de Vries M, Sebert S, Kere J, Karlsson R, Arshad SH, Hämäläinen E, Routledge MN, Boomsma DI, Feinberg AP, Newschaffer CJ, Govarts E, Moisse M, Fallin MD, Melén E, Prentice AM, Kajantie E, Almqvist C, Oken E, Dabelea D, Boezen HM, Melton PE, Wright RJ, Koppelman GH, Trevisi L, Hivert MF, Sunyer J, Munthe-Kaas MC, Murphy SK, Corpeleijn E, Wiemels J, Holland N, Herceg Z, Binder EB, Davey Smith G, Jaddoe VWV, Lie RT, Nystad W, London SJ, Lawlor DA, Relton CL, Snieder H, Felix JF.

Nat Commun. 2019 Apr 23;10(1):1893. doi: 10.1038/s41467-019-09671-3.

9.

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease.

Schiller HB, Montoro DT, Simon LM, Rawlins EL, Meyer KB, Strunz M, Vieira Braga FA, Timens W, Koppelman GH, Budinger GRS, Burgess JK, Waghray A, van den Berge M, Theis FJ, Regev A, Kaminski N, Rajagopal J, Teichmann SA, Misharin AV, Nawijn MC.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):31-41. doi: 10.1165/rcmb.2018-0416TR.

PMID:
30995076
10.

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, Heuckeroth RO, Potter SS, Vella LA, Terry NA, Ghanem LR, Kennedy BC, Helbig I, Sullivan KE, Castelo-Soccio L, Kreigstein A, Herse F, Nawijn MC, Koppelman GH, Haendel M, Harris NL, Rokita JL, Zhang Y, Regev A, Rozenblatt-Rosen O, Rood JE, Tickle TL, Vento-Tormo R, Alimohamed S, Lek M, Mar JC, Loomes KM, Barrett DM, Uapinyoying P, Beggs AH, Agrawal PB, Chen YW, Muir AB, Garmire LX, Snapper SB, Nazarian J, Seeholzer SH, Fazelinia H, Singh LN, Faryabi RB, Raman P, Dawany N, Xie HM, Devkota B, Diskin SJ, Anderson SA, Rappaport EF, Peranteau W, Wikenheiser-Brokamp KA, Teichmann S, Wallace D, Peng T, Ding YY, Kim MS, Xing Y, Kong SW, Bönnemann CG, Mandl KD, White PS.

Dev Cell. 2019 Apr 8;49(1):10-29. doi: 10.1016/j.devcel.2019.03.001. Epub 2019 Mar 28. Review.

11.

Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

Ferreira MAR, Mathur R, Vonk JM, Szwajda A, Brumpton B, Granell R, Brew BK, Ullemar V, Lu Y, Jiang Y; 23andMe Research Team; eQTLGen Consortium; BIOS Consortium, Magnusson PKE, Karlsson R, Hinds DA, Paternoster L, Koppelman GH, Almqvist C.

Am J Hum Genet. 2019 Apr 4;104(4):665-684. doi: 10.1016/j.ajhg.2019.02.022. Epub 2019 Mar 28.

PMID:
30929738
12.

Breastfeeding and cardiometabolic markers at age 12: a population-based birth cohort study.

Pluymen LPM, Wijga AH, Gehring U, Koppelman GH, Smit HA, van Rossem L.

Int J Obes (Lond). 2019 Mar 18. doi: 10.1038/s41366-018-0317-5. [Epub ahead of print]

PMID:
30886238
13.

Applying the CAMP trial asthma remission prediction model to the Dutch asthma remission studies.

Carpaij OA, Vonk JM, Nawijn MC, Kerstjens HAM, Koppelman GH, van den Berge M.

J Allergy Clin Immunol. 2019 May;143(5):1973-1975. doi: 10.1016/j.jaci.2019.01.040. Epub 2019 Mar 12. No abstract available.

PMID:
30876728
14.

Effect of long-term corticosteroid treatment on microRNA and gene-expression profiles in COPD.

Faiz A, Steiling K, Roffel MP, Postma DS, Spira A, Lenburg ME, Borggrewe M, Eijgenraam TR, Jonker MR, Koppelman GH, Pouwels SD, Liu G, Alekseyev YO, Lam S, Hiemstra PS, Sterk PJ, Timens W, Brandsma CA, Heijink IH, van den Berge M.

Eur Respir J. 2019 Apr 25;53(4). pii: 1801202. doi: 10.1183/13993003.01202-2018. Print 2019 Apr.

PMID:
30846474
15.

Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis.

Berkers G, van Mourik P, Vonk AM, Kruisselbrink E, Dekkers JF, de Winter-de Groot KM, Arets HGM, Marck-van der Wilt REP, Dijkema JS, Vanderschuren MM, Houwen RHJ, Heijerman HGM, van de Graaf EA, Elias SG, Majoor CJ, Koppelman GH, Roukema J, Bakker M, Janssens HM, van der Meer R, Vries RGJ, Clevers HC, de Jonge HR, Beekman JM, van der Ent CK.

Cell Rep. 2019 Feb 12;26(7):1701-1708.e3. doi: 10.1016/j.celrep.2019.01.068.

16.

Does breast milk adiponectin affect BMI and cardio-metabolic markers in childhood?

van Rossem L, Smit HA, Lentjes EGWM, Maitimu-Smeele I, Brunekreef B, Koppelman GH, Wijga AH.

Br J Nutr. 2019 Apr;121(8):905-913. doi: 10.1017/S0007114519000266. Epub 2019 Feb 7.

PMID:
30728088
17.

Precision medicine in childhood asthma.

Slob EM, Maitland-Van der Zee AH, Koppelman GH, Pijnenburg MW.

Curr Opin Allergy Clin Immunol. 2019 Apr;19(2):141-147. doi: 10.1097/ACI.0000000000000517.

PMID:
30649013
18.

High-Throughput Sequencing in Respiratory, Critical Care, and Sleep Medicine Research. An Official American Thoracic Society Workshop Report.

Hersh CP, Adcock IM, Celedón JC, Cho MH, Christiani DC, Himes BE, Kaminski N, Mathias RA, Meyers DA, Quackenbush J, Redline S, Steiling KA, Tabor HK, Tobin MD, Wurfel MM, Yang IV, Koppelman GH.

Ann Am Thorac Soc. 2019 Jan;16(1):1-16. doi: 10.1513/AnnalsATS.201810-716WS.

19.

DNA methylation in nasal epithelium, atopy, and atopic asthma in children: a genome-wide study.

Forno E, Wang T, Qi C, Yan Q, Xu CJ, Boutaoui N, Han YY, Weeks DE, Jiang Y, Rosser F, Vonk JM, Brouwer S, Acosta-Perez E, Colón-Semidey A, Alvarez M, Canino G, Koppelman GH, Chen W, Celedón JC.

Lancet Respir Med. 2019 Apr;7(4):336-346. doi: 10.1016/S2213-2600(18)30466-1. Epub 2018 Dec 21.

PMID:
30584054
20.

Epigenome-wide meta-analysis of DNA methylation and childhood asthma.

Reese SE, Xu CJ, den Dekker HT, Lee MK, Sikdar S, Ruiz-Arenas C, Merid SK, Rezwan FI, Page CM, Ullemar V, Melton PE, Oh SS, Yang IV, Burrows K, Söderhäll C, Jima DD, Gao L, Arathimos R, Küpers LK, Wielscher M, Rzehak P, Lahti J, Laprise C, Madore AM, Ward J, Bennett BD, Wang T, Bell DA; BIOS consortium, Vonk JM, Håberg SE, Zhao S, Karlsson R, Hollams E, Hu D, Richards AJ, Bergström A, Sharp GC, Felix JF, Bustamante M, Gruzieva O, Maguire RL, Gilliland F, Baïz N, Nohr EA, Corpeleijn E, Sebert S, Karmaus W, Grote V, Kajantie E, Magnus MC, Örtqvist AK, Eng C, Liu AH, Kull I, Jaddoe VWV, Sunyer J, Kere J, Hoyo C, Annesi-Maesano I, Arshad SH, Koletzko B, Brunekreef B, Binder EB, Räikkönen K, Reischl E, Holloway JW, Jarvelin MR, Snieder H, Kazmi N, Breton CV, Murphy SK, Pershagen G, Anto JM, Relton CL, Schwartz DA, Burchard EG, Huang RC, Nystad W, Almqvist C, Henderson AJ, Melén E, Duijts L, Koppelman GH, London SJ.

J Allergy Clin Immunol. 2019 Jun;143(6):2062-2074. doi: 10.1016/j.jaci.2018.11.043. Epub 2018 Dec 21.

21.

The associations of air pollution, traffic noise and green space with overweight throughout childhood: The PIAMA birth cohort study.

Bloemsma LD, Wijga AH, Klompmaker JO, Janssen NAH, Smit HA, Koppelman GH, Brunekreef B, Lebret E, Hoek G, Gehring U.

Environ Res. 2019 Feb;169:348-356. doi: 10.1016/j.envres.2018.11.026. Epub 2018 Nov 20.

22.

Childhood infections and common carotid intima media thickness in adolescence.

Prins-van Ginkel AC, Bruijning-Verhagen PCJ, Wijga AH, Bots ML, Gehring U, van der Hoek W, Koppelman GH, van Rossem L, Uiterwaal CSPM, Smit HA, van der Sande MAB.

Epidemiol Infect. 2018 Nov 8:1-7. doi: 10.1017/S095026881800287X. [Epub ahead of print]

23.

Associations of residential exposure to agricultural pesticides with asthma prevalence in adolescence: The PIAMA birth cohort.

Bukalasa JS, Brunekreef B, Brouwer M, Koppelman GH, Wijga AH, Huss A, Gehring U.

Environ Int. 2018 Dec;121(Pt 1):435-442. doi: 10.1016/j.envint.2018.09.029. Epub 2018 Sep 25.

24.

Air pollution exposure and lung function until age 16 years: the PIAMA birth cohort study.

Milanzi EB, Koppelman GH, Smit HA, Wijga AH, Oldenwening M, Vonk JM, Brunekreef B, Gehring U.

Eur Respir J. 2018 Sep 27;52(3). pii: 1800218. doi: 10.1183/13993003.00218-2018. Print 2018 Sep.

PMID:
30139777
25.

Air pollution and airway resistance at age 8 years - the PIAMA birth cohort study.

Finke I, de Jongste JC, Smit HA, Wijga AH, Koppelman GH, Vonk J, Brunekreef B, Gehring U.

Environ Health. 2018 Jul 17;17(1):61. doi: 10.1186/s12940-018-0407-9.

26.

Pharmacogenetics of inhaled long-acting beta2-agonists in asthma: A systematic review.

Slob EMA, Vijverberg SJH, Palmer CNA, Zazuli Z, Farzan N, Oliveri NMB, Pijnenburg MW, Koppelman GH, Maitland-van der Zee AH.

Pediatr Allergy Immunol. 2018 Nov;29(7):705-714. doi: 10.1111/pai.12956. Epub 2018 Aug 12.

PMID:
29992699
27.

Greater severity of peanut challenge reactions using a high-fat vs low-fat matrix vehicle.

Pettersson ME, Koppelman GH, Schins AMM, van Ginkel CD, Flokstra-de Blok BMJ, Kollen BJ, Dubois AEJ.

Clin Exp Allergy. 2018 Oct;48(10):1364-1367. doi: 10.1111/cea.13210. Epub 2018 Jul 26. No abstract available.

PMID:
29908083
28.

Novel genes and insights in complete asthma remission: A genome-wide association study on clinical and complete asthma remission.

Vonk JM, Nieuwenhuis MAE, Dijk FN, Boudier A, Siroux V, Bouzigon E, Probst-Hensch N, Imboden M, Keidel D, Sin D, Bossé Y, Hao K, van den Berge M, Faiz A, Koppelman GH, Postma DS.

Clin Exp Allergy. 2018 Oct;48(10):1286-1296. doi: 10.1111/cea.13181. Epub 2018 Jun 19.

PMID:
29786918
29.

Response to letters to the editor regarding our paper "Early introduction of complementary foods and childhood overweight in breastfed and formula-fed infants in the Netherlands: the PIAMA birth cohort study".

Pluymen LPM, Wijga AH, Gehring U, Koppelman GH, Smit HA, van Rossem L.

Eur J Nutr. 2018 Aug;57(5):1999-2000. doi: 10.1007/s00394-018-1701-6. No abstract available.

PMID:
29766291
30.

What do we need to transfer pharmacogenetics findings into the clinic?

Slob EMA, Vijverberg SJH, Pijnenburg MW, Koppelman GH, Maitland-van der Zee AH.

Pharmacogenomics. 2018 May;19(7):589-592. doi: 10.2217/pgs-2018-0026. Epub 2018 Apr 27. No abstract available.

31.

Eleven loci with new reproducible genetic associations with allergic disease risk.

Ferreira MAR, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, Lu Y, Rüschendorf F; 23andMe Research Team; SHARE study, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jorgenson E, Lee YA, Boomsma DI, Karlsson R, Almqvist C, Koppelman GH, Paternoster L.

J Allergy Clin Immunol. 2019 Feb;143(2):691-699. doi: 10.1016/j.jaci.2018.03.012. Epub 2018 Apr 19.

PMID:
29679657
32.

Maternal Smoking during Pregnancy and Early Childhood and Development of Asthma and Rhinoconjunctivitis - a MeDALL Project.

Thacher JD, Gehring U, Gruzieva O, Standl M, Pershagen G, Bauer CP, Berdel D, Keller T, Koletzko S, Koppelman GH, Kull I, Lau S, Lehmann I, Maier D, Schikowski T, Wahn U, Wijga AH, Heinrich J, Bousquet J, Anto JM, von Berg A, Melén E, Smit HA, Keil T, Bergström A.

Environ Health Perspect. 2018 Apr 12;126(4):047005. doi: 10.1289/EHP2738.

33.

Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life.

Hüls A, Klümper C, MacIntyre EA, Brauer M, Melén E, Bauer M, Berdel D, Bergström A, Brunekreef B, Chan-Yeung M, Fuertes E, Gehring U, Gref A, Heinrich J, Standl M, Lehmann I, Kerkhof M, Koppelman GH, Kozyrskyj AL, Pershagen G, Carlsten C, Krämer U, Schikowski T; TAG Study Group.

Pediatr Allergy Immunol. 2018 Sep;29(6):596-605. doi: 10.1111/pai.12903. Epub 2018 May 7.

34.

Promoting respiratory public health through epigenetics research: an ERS Environment Health Committee workshop report.

Melén E, Barouki R, Barry M, Boezen HM, Hoffmann B, Krauss-Etschmann S, Koppelman GH, Forsberg B.

Eur Respir J. 2018 Apr 4;51(4). pii: 1702410. doi: 10.1183/13993003.02410-2017. Print 2018 Apr. No abstract available.

PMID:
29618601
35.

Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and expression Quantitative Trait Loci.

Imkamp K, Berg M, Vermeulen CJ, Heijink IH, Guryev V, Kerstjens HAM, Koppelman GH, van den Berge M, Faiz A.

J Allergy Clin Immunol. 2018 Jul;142(1):314-317.e15. doi: 10.1016/j.jaci.2018.01.047. Epub 2018 Mar 6. No abstract available.

PMID:
29522853
36.

Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma.

Dijk FN, Xu C, Melén E, Carsin AE, Kumar A, Nolte IM, Gruzieva O, Pershagen G, Grotenboer NS, Savenije OEM, Antó JM, Lavi I, Dobaño C, Bousquet J, van der Vlies P, van der Valk RJP, de Jongste JC, Nawijn MC, Guerra S, Postma DS, Koppelman GH.

Eur Respir J. 2018 Mar 8;51(3). pii: 1701377. doi: 10.1183/13993003.01377-2017. Print 2018 Mar.

PMID:
29519908
37.

Blood Eosinophil Count and Metabolic, Cardiac and Pulmonary Outcomes: A Mendelian Randomization Study.

Amini M, Vonk JM, Abbasi A, Prins BP, Bruinenberg M, Franke L, van der Harst P, Navis G, Koppelman GH, Wolffenbuttel BHR, Boezen HM, Snieder H, Chasman DI, Alizadeh BZ.

Twin Res Hum Genet. 2018 Apr;21(2):89-100. doi: 10.1017/thg.2018.6. Epub 2018 Mar 6.

PMID:
29506594
38.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium, van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH.

Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26.

39.

Early introduction of complementary foods and childhood overweight in breastfed and formula-fed infants in the Netherlands: the PIAMA birth cohort study.

Pluymen LPM, Wijga AH, Gehring U, Koppelman GH, Smit HA, van Rossem L.

Eur J Nutr. 2018 Aug;57(5):1985-1993. doi: 10.1007/s00394-018-1639-8. Epub 2018 Feb 22.

40.

Retrospective observational cohort study regarding the effect of breastfeeding on challenge-proven food allergy.

van Ginkel CD, van der Meulen GN, Bak E, Flokstra-de Blok BMJ, Kollen BJ, Koppelman GH, Dubois AEJ.

Eur J Clin Nutr. 2018 Apr;72(4):557-563. doi: 10.1038/s41430-018-0117-y. Epub 2018 Feb 19.

PMID:
29459789
41.

Association of STAT6 gene variants with food allergy diagnosed by double-blind placebo-controlled food challenges.

van Ginkel CD, Pettersson ME, Dubois AEJ, Koppelman GH.

Allergy. 2018 Jun;73(6):1337-1341. doi: 10.1111/all.13432. Epub 2018 Apr 6.

42.

Prediction of the severity of allergic reactions to foods.

Pettersson ME, Koppelman GH, Flokstra-de Blok BMJ, Kollen BJ, Dubois AEJ.

Allergy. 2018 Jul;73(7):1532-1540. doi: 10.1111/all.13423. Epub 2018 Mar 4.

43.

A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma.

Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Yin D, Ellis G, Ben-Shoshan M, Marenholz I, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk R, Dubois AEJ, Grosche S, Ashley S, Rüschendorf F, Kalb B, Beyer K, Nöthen MM, Lee YA, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D.

J Allergy Clin Immunol. 2018 Apr;141(4):1513-1516. doi: 10.1016/j.jaci.2017.10.047. Epub 2018 Jan 8. No abstract available.

PMID:
29325868
44.

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, Cookson WOC, Altmüller J, Ang W, Barr RG, Beaty TH, Becker AB, Beilby J, Bisgaard H, Bjornsdottir US, Bleecker E, Bønnelykke K, Boomsma DI, Bouzigon E, Brightling CE, Brossard M, Brusselle GG, Burchard E, Burkart KM, Bush A, Chan-Yeung M, Chung KF, Couto Alves A, Curtin JA, Custovic A, Daley D, de Jongste JC, Del-Rio-Navarro BE, Donohue KM, Duijts L, Eng C, Eriksson JG, Farrall M, Fedorova Y, Feenstra B, Ferreira MA; Australian Asthma Genetics Consortium (AAGC) collaborators, Freidin MB, Gajdos Z, Gauderman J, Gehring U, Geller F, Genuneit J, Gharib SA, Gilliland F, Granell R, Graves PE, Gudbjartsson DF, Haahtela T, Heckbert SR, Heederik D, Heinrich J, Heliövaara M, Henderson J, Himes BE, Hirose H, Hirschhorn JN, Hofman A, Holt P, Hottenga J, Hudson TJ, Hui J, Imboden M, Ivanov V, Jaddoe VWV, James A, Janson C, Jarvelin MR, Jarvis D, Jones G, Jonsdottir I, Jousilahti P, Kabesch M, Kähönen M, Kantor DB, Karunas AS, Khusnutdinova E, Koppelman GH, Kozyrskyj AL, Kreiner E, Kubo M, Kumar R, Kumar A, Kuokkanen M, Lahousse L, Laitinen T, Laprise C, Lathrop M, Lau S, Lee YA, Lehtimäki T, Letort S, Levin AM, Li G, Liang L, Loehr LR, London SJ, Loth DW, Manichaikul A, Marenholz I, Martinez FJ, Matheson MC, Mathias RA, Matsumoto K, Mbarek H, McArdle WL, Melbye M, Melén E, Meyers D, Michel S, Mohamdi H, Musk AW, Myers RA, Nieuwenhuis MAE, Noguchi E, O'Connor GT, Ogorodova LM, Palmer CD, Palotie A, Park JE, Pennell CE, Pershagen G, Polonikov A, Postma DS, Probst-Hensch N, Puzyrev VP, Raby BA, Raitakari OT, Ramasamy A, Rich SS, Robertson CF, Romieu I, Salam MT, Salomaa V, Schlünssen V, Scott R, Selivanova PA, Sigsgaard T, Simpson A, Siroux V, Smith LJ, Solodilova M, Standl M, Stefansson K, Strachan DP, Stricker BH, Takahashi A, Thompson PJ, Thorleifsson G, Thorsteinsdottir U, Tiesler CMT, Torgerson DG, Tsunoda T, Uitterlinden AG, van der Valk RJP, Vaysse A, Vedantam S, von Berg A, von Mutius E, Vonk JM, Waage J, Wareham NJ, Weiss ST, White WB, Wickman M, Widén E, Willemsen G, Williams LK, Wouters IM, Yang JJ, Zhao JH, Moffatt MF, Ober C, Nicolae DL.

Nat Genet. 2018 Jan;50(1):42-53. doi: 10.1038/s41588-017-0014-7. Epub 2017 Dec 22.

45.

Drugs during pregnancy and breast feeding in women diagnosed with Cystic Fibrosis - An update.

Kroon MAGM, Akkerman-Nijland AM, Rottier BL, Koppelman GH, Akkerman OW, Touw DJ.

J Cyst Fibros. 2018 Jan;17(1):17-25. doi: 10.1016/j.jcf.2017.11.009. Epub 2017 Dec 7. No abstract available.

PMID:
29233472
46.

Identification of atopic dermatitis subgroups in children from 2 longitudinal birth cohorts.

Paternoster L, Savenije OEM, Heron J, Evans DM, Vonk JM, Brunekreef B, Wijga AH, Henderson AJ, Koppelman GH, Brown SJ.

J Allergy Clin Immunol. 2018 Mar;141(3):964-971. doi: 10.1016/j.jaci.2017.09.044. Epub 2017 Nov 10.

47.

Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

Ferreira MA, Vonk JM, Baurecht H, Marenholz I, Tian C, Hoffman JD, Helmer Q, Tillander A, Ullemar V, van Dongen J, Lu Y, Rüschendorf F, Esparza-Gordillo J, Medway CW, Mountjoy E, Burrows K, Hummel O, Grosche S, Brumpton BM, Witte JS, Hottenga JJ, Willemsen G, Zheng J, Rodríguez E, Hotze M, Franke A, Revez JA, Beesley J, Matheson MC, Dharmage SC, Bain LM, Fritsche LG, Gabrielsen ME, Balliu B; 23andMe Research Team; AAGC collaborators; BIOS consortium; LifeLines Cohort Study, Nielsen JB, Zhou W, Hveem K, Langhammer A, Holmen OL, Løset M, Abecasis GR, Willer CJ, Arnold A, Homuth G, Schmidt CO, Thompson PJ, Martin NG, Duffy DL, Novak N, Schulz H, Karrasch S, Gieger C, Strauch K, Melles RB, Hinds DA, Hübner N, Weidinger S, Magnusson PKE, Jansen R, Jorgenson E, Lee YA, Boomsma DI, Almqvist C, Karlsson R, Koppelman GH, Paternoster L.

Nat Genet. 2017 Dec;49(12):1752-1757. doi: 10.1038/ng.3985. Epub 2017 Oct 30.

48.

Genome-wide association study and meta-analysis in multiple populations identifies new loci for peanut allergy and establishes C11orf30/EMSY as a genetic risk factor for food allergy.

Asai Y, Eslami A, van Ginkel CD, Akhabir L, Wan M, Ellis G, Ben-Shoshan M, Martino D, Ferreira MA, Allen K, Mazer B, de Groot H, de Jong NW, Gerth van Wijk RN, Dubois AEJ, Chin R, Cheuk S, Hoffman J, Jorgensen E, Witte JS, Melles RB, Hong X, Wang X, Hui J, Musk AWB, Hunter M, James AL, Koppelman GH, Sandford AJ, Clarke AE, Daley D.

J Allergy Clin Immunol. 2018 Mar;141(3):991-1001. doi: 10.1016/j.jaci.2017.09.015. Epub 2017 Oct 10.

49.

Cohort Profile: Pregnancy And Childhood Epigenetics (PACE) Consortium.

Felix JF, Joubert BR, Baccarelli AA, Sharp GC, Almqvist C, Annesi-Maesano I, Arshad H, Baïz N, Bakermans-Kranenburg MJ, Bakulski KM, Binder EB, Bouchard L, Breton CV, Brunekreef B, Brunst KJ, Burchard EG, Bustamante M, Chatzi L, Cheng Munthe-Kaas M, Corpeleijn E, Czamara D, Dabelea D, Davey Smith G, De Boever P, Duijts L, Dwyer T, Eng C, Eskenazi B, Everson TM, Falahi F, Fallin MD, Farchi S, Fernandez MF, Gao L, Gaunt TR, Ghantous A, Gillman MW, Gonseth S, Grote V, Gruzieva O, Håberg SE, Herceg Z, Hivert MF, Holland N, Holloway JW, Hoyo C, Hu D, Huang RC, Huen K, Järvelin MR, Jima DD, Just AC, Karagas MR, Karlsson R, Karmaus W, Kechris KJ, Kere J, Kogevinas M, Koletzko B, Koppelman GH, Küpers LK, Ladd-Acosta C, Lahti J, Lambrechts N, Langie SAS, Lie RT, Liu AH, Magnus MC, Magnus P, Maguire RL, Marsit CJ, McArdle W, Melén E, Melton P, Murphy SK, Nawrot TS, Nisticò L, Nohr EA, Nordlund B, Nystad W, Oh SS, Oken E, Page CM, Perron P, Pershagen G, Pizzi C, Plusquin M, Raikkonen K, Reese SE, Reischl E, Richiardi L, Ring S, Roy RP, Rzehak P, Schoeters G, Schwartz DA, Sebert S, Snieder H, Sørensen TIA, Starling AP, Sunyer J, Taylor JA, Tiemeier H, Ullemar V, Vafeiadi M, Van Ijzendoorn MH, Vonk JM, Vriens A, Vrijheid M, Wang P, Wiemels JL, Wilcox AJ, Wright RJ, Xu CJ, Xu Z, Yang IV, Yousefi P, Zhang H, Zhang W, Zhao S, Agha G, Relton CL, Jaddoe VWV, London SJ.

Int J Epidemiol. 2018 Feb 1;47(1):22-23u. doi: 10.1093/ije/dyx190. No abstract available. Erratum in: Int J Epidemiol. 2018 Feb 1;47(1):24.

50.

Maternal BMI at the start of pregnancy and offspring epigenome-wide DNA methylation: findings from the pregnancy and childhood epigenetics (PACE) consortium.

Sharp GC, Salas LA, Monnereau C, Allard C, Yousefi P, Everson TM, Bohlin J, Xu Z, Huang RC, Reese SE, Xu CJ, Baïz N, Hoyo C, Agha G, Roy R, Holloway JW, Ghantous A, Merid SK, Bakulski KM, Küpers LK, Zhang H, Richmond RC, Page CM, Duijts L, Lie RT, Melton PE, Vonk JM, Nohr EA, Williams-DeVane C, Huen K, Rifas-Shiman SL, Ruiz-Arenas C, Gonseth S, Rezwan FI, Herceg Z, Ekström S, Croen L, Falahi F, Perron P, Karagas MR, Quraishi BM, Suderman M, Magnus MC, Jaddoe VWV, Taylor JA, Anderson D, Zhao S, Smit HA, Josey MJ, Bradman A, Baccarelli AA, Bustamante M, Håberg SE, Pershagen G, Hertz-Picciotto I, Newschaffer C, Corpeleijn E, Bouchard L, Lawlor DA, Maguire RL, Barcellos LF, Davey Smith G, Eskenazi B, Karmaus W, Marsit CJ, Hivert MF, Snieder H, Fallin MD, Melén E, Munthe-Kaas MC, Arshad H, Wiemels JL, Annesi-Maesano I, Vrijheid M, Oken E, Holland N, Murphy SK, Sørensen TIA, Koppelman GH, Newnham JP, Wilcox AJ, Nystad W, London SJ, Felix JF, Relton CL.

Hum Mol Genet. 2017 Oct 15;26(20):4067-4085. doi: 10.1093/hmg/ddx290.

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