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Items: 1 to 50 of 88

1.

Molecular mechanism of a potassium channel gating through activation gate-selectivity filter coupling.

Kopec W, Rothberg BS, de Groot BL.

Nat Commun. 2019 Nov 26;10(1):5366. doi: 10.1038/s41467-019-13227-w.

2.

The conduction pathway of potassium channels is water free under physiological conditions.

Öster C, Hendriks K, Kopec W, Chevelkov V, Shi C, Michl D, Lange S, Sun H, de Groot BL, Lange A.

Sci Adv. 2019 Jul 31;5(7):eaaw6756. doi: 10.1126/sciadv.aaw6756. eCollection 2019 Jul.

3.

Conotoxin κM-RIIIJ, a tool targeting asymmetric heteromeric Kv1 channels.

Cordeiro S, Finol-Urdaneta RK, Köpfer D, Markushina A, Song J, French RJ, Kopec W, de Groot BL, Giacobassi MJ, Leavitt LS, Raghuraman S, Teichert RW, Olivera BM, Terlau H.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):1059-1064. doi: 10.1073/pnas.1813161116. Epub 2018 Dec 28.

4.

K+ binding and proton redistribution in the E2P state of the H+, K+-ATPase.

Dubey V, Han M, Kopec W, Solov'yov IA, Abe K, Khandelia H.

Sci Rep. 2018 Aug 24;8(1):12732. doi: 10.1038/s41598-018-30885-w.

5.

Direct knock-on of desolvated ions governs strict ion selectivity in K+ channels.

Kopec W, Köpfer DA, Vickery ON, Bondarenko AS, Jansen TLC, de Groot BL, Zachariae U.

Nat Chem. 2018 Aug;10(8):813-820. doi: 10.1038/s41557-018-0105-9. Epub 2018 Jul 20.

PMID:
30030538
6.

In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways.

Heinz LP, Kopec W, de Groot BL, Fink RHA.

Sci Rep. 2018 May 2;8(1):6886. doi: 10.1038/s41598-018-25061-z.

7.

Correction to: The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.

Tranebjærg L, Strenzke N, Lindholm S, Rendtorff ND, Poulsen H, Khandelia H, Kopec W, Lyngbye TJB, Hamel C, Delettre C, Bocquet B, Bille M, Owen HH, Bek T, Jensen H, Østergaard K, Möller C, Luxon L, Carr L, Wilson L, Rajput K, Sirimanna T, Harrop-Griffiths K, Rahman S, Vona B, Doll J, Haaf T, Bartsch O, Rosewich H, Moser T, Bitner-Glindzicz M.

Hum Genet. 2018 Mar;137(3):279-280. doi: 10.1007/s00439-018-1870-7.

PMID:
29435658
8.

New keratinolytic bacteria in valorization of chicken feather waste.

Łaba W, Żarowska B, Chorążyk D, Pudło A, Piegza M, Kancelista A, Kopeć W.

AMB Express. 2018 Jan 24;8(1):9. doi: 10.1186/s13568-018-0538-y.

9.

The CAPOS mutation in ATP1A3 alters Na/K-ATPase function and results in auditory neuropathy which has implications for management.

Tranebjærg L, Strenzke N, Lindholm S, Rendtorff ND, Poulsen H, Khandelia H, Kopec W, Lyngbye TJB, Hamel C, Delettre C, Bocquet B, Bille M, Owen HH, Bek T, Jensen H, Østergaard K, Möller C, Luxon L, Carr L, Wilson L, Rajput K, Sirimanna T, Harrop-Griffiths K, Rahman S, Vona B, Doll J, Haaf T, Bartsch O, Rosewich H, Moser T, Bitner-Glindzicz M.

Hum Genet. 2018 Feb;137(2):111-127. doi: 10.1007/s00439-017-1862-z. Epub 2018 Jan 5. Erratum in: Hum Genet. 2018 Feb 12;:.

PMID:
29305691
10.

Effect of Polycation Structure on Interaction with Lipid Membranes.

Wilkosz N, Jamróz D, Kopeć W, Nakai K, Yusa SI, Wytrwal-Sarna M, Bednar J, Nowakowska M, Kepczynski M.

J Phys Chem B. 2017 Aug 3;121(30):7318-7326. doi: 10.1021/acs.jpcb.7b05248. Epub 2017 Jul 19.

PMID:
28678504
11.

Glutamate Water Gates in the Ion Binding Pocket of Na+ Bound Na+, K+-ATPase.

Han M, Kopec W, Solov'yov IA, Khandelia H.

Sci Rep. 2017 Jan 13;7:39829. doi: 10.1038/srep39829.

12.

Increased Granulocyte Heparanase Activity in Neutrophils from Patients with Lupus Nephritis and Idiopathic Membranous Nephropathy.

Szymczak M, Kuźniar J, Kopeć W, Żabińska M, Marchewka Z, Kościelska-Kasprzak K, Klinger M.

Arch Immunol Ther Exp (Warsz). 2017 Feb;65(1):83-91. doi: 10.1007/s00005-016-0396-8. Epub 2016 Apr 18.

13.

Maintaining Perioperative Normothermia: Sustaining an Evidence-Based Practice Improvement Project.

Levin RF, Wright F, Pecoraro K, Kopec W.

AORN J. 2016 Feb;103(2):213.e1-213.e13. doi: 10.1016/j.aorn.2015.12.020.

PMID:
26849994
14.

Tuning of the Na,K-ATPase by the beta subunit.

Hilbers F, Kopec W, Isaksen TJ, Holm TH, Lykke-Hartmann K, Nissen P, Khandelia H, Poulsen H.

Sci Rep. 2016 Feb 5;6:20442. doi: 10.1038/srep20442.

15.

Accelerating All-Atom MD Simulations of Lipids Using a Modified Virtual-Sites Technique.

Loubet B, Kopec W, Khandelia H.

J Chem Theory Comput. 2014 Dec 9;10(12):5690-5. doi: 10.1021/ct500100f.

PMID:
26583251
16.

Antioxidant status of turkey breast meat and blood after feeding a diet enriched with histidine.

Kopec W, Wiliczkiewicz A, Jamroz D, Biazik E, Pudlo A, Hikawczuk T, Skiba T, Korzeniowska M.

Poult Sci. 2016 Jan;95(1):53-61. doi: 10.3382/ps/pev311. Epub 2015 Nov 14.

17.

Membrane accessibility of glutathione.

Garcia A, Eljack ND, Sani MA, Separovic F, Rasmussen HH, Kopec W, Khandelia H, Cornelius F, Clarke RJ.

Biochim Biophys Acta. 2015 Oct;1848(10 Pt A):2430-6. doi: 10.1016/j.bbamem.2015.07.016. Epub 2015 Jul 30.

18.

The N Terminus of Sarcolipin Plays an Important Role in Uncoupling Sarco-endoplasmic Reticulum Ca2+-ATPase (SERCA) ATP Hydrolysis from Ca2+ Transport.

Sahoo SK, Shaikh SA, Sopariwala DH, Bal NC, Bruhn DS, Kopec W, Khandelia H, Periasamy M.

J Biol Chem. 2015 May 29;290(22):14057-67. doi: 10.1074/jbc.M115.636738. Epub 2015 Apr 16.

19.

K+ congeners that do not compromise Na+ activation of the Na+,K+-ATPase: hydration of the ion binding cavity likely controls ion selectivity.

Mahmmoud YA, Kopec W, Khandelia H.

J Biol Chem. 2015 Feb 6;290(6):3720-31. doi: 10.1074/jbc.M114.577486. Epub 2014 Dec 22.

20.

Influence of l-carnosine on pro-antioxidant status in elite kayakers and canoeists.

Slowinska-Lisowska M, Zembron-Lacny A, Rynkiewicz M, Rynkiewicz T, Kopec W.

Acta Physiol Hung. 2014 Dec;101(4):461-70. doi: 10.1556/APhysiol.101.2014.008.

PMID:
25201708
21.

Anserine and carnosine supplementation in the elderly: Effects on cognitive functioning and physical capacity.

Szcześniak D, Budzeń S, Kopeć W, Rymaszewska J.

Arch Gerontol Geriatr. 2014 Sep-Oct;59(2):485-90. doi: 10.1016/j.archger.2014.04.008. Epub 2014 May 2.

PMID:
24880197
22.

Insights into the role of cyclic ladderane lipids in bacteria from computer simulations.

Chaban VV, Nielsen MB, Kopec W, Khandelia H.

Chem Phys Lipids. 2014 Jul;181:76-82. doi: 10.1016/j.chemphyslip.2014.04.002. Epub 2014 Apr 13.

PMID:
24732581
23.

Reinforcing the membrane-mediated mechanism of action of the anti-tuberculosis candidate drug thioridazine with molecular simulations.

Kopec W, Khandelia H.

J Comput Aided Mol Des. 2014 Feb;28(2):123-34. doi: 10.1007/s10822-014-9737-z. Epub 2014 Mar 1.

PMID:
24577873
24.

Molecular mechanism of Na(+),K(+)-ATPase malfunction in mutations characteristic of adrenal hypertension.

Kopec W, Loubet B, Poulsen H, Khandelia H.

Biochemistry. 2014 Feb 4;53(4):746-54. doi: 10.1021/bi401425g. Epub 2014 Jan 24.

PMID:
24428543
25.

Production and characterization of egg yolk antibodies against bovine alimentary tract pathogens.

Sitnik O, Jawor P, Kopeć W, Skiba T, Stefaniak T.

Pol J Vet Sci. 2013;16(2):283-91.

PMID:
23971196
26.

Influence of different histidine sources and zinc supplementation of broiler diets on dipeptide content and antioxidant status of blood and meat.

Kopeć W, Jamroz D, Wiliczkiewicz A, Biazik E, Pudlo A, Hikawczuk T, Skiba T, Korzeniowska M.

Br Poult Sci. 2013;54(4):454-65. doi: 10.1080/00071668.2013.793295. Epub 2013 Jun 14.

PMID:
23768017
27.

Molecular dynamics simulations of the interactions of medicinal plant extracts and drugs with lipid bilayer membranes.

Kopeć W, Telenius J, Khandelia H.

FEBS J. 2013 Jun;280(12):2785-805. doi: 10.1111/febs.12286. Epub 2013 May 16. Review.

28.

Conformations of double-headed, triple-tailed phospholipid oxidation lipid products in model membranes.

Hermetter A, Kopec W, Khandelia H.

Biochim Biophys Acta. 2013 Aug;1828(8):1700-6. doi: 10.1016/j.bbamem.2013.03.030. Epub 2013 Apr 6.

29.

Antioxidation status and histidine dipeptides content in broiler blood and muscles depending on protein sources in feed.

Kopeć W, Jamroz D, Wiliczkiewicz A, Biazik E, Hikawczuk T, Skiba T, Pudło A, Orda J.

J Anim Physiol Anim Nutr (Berl). 2013 Jun;97(3):586-98. doi: 10.1111/j.1439-0396.2012.01303.x. Epub 2012 Apr 26.

PMID:
22533382
30.

Imbalance of metallaproteinase/tissue inhibitors of metalloproteinase system in renal transplant recipients with chronic allograft injury.

Mazanowska O, Kamińska D, Krajewska M, Zabińska M, Kopeć W, Boratyńska M, Chudoba P, Patrzalek D, Klinger M.

Transplant Proc. 2011 Oct;43(8):3000-3. doi: 10.1016/j.transproceed.2011.08.012.

PMID:
21996210
31.

Endostatin and vascular endothelial growth factor: potential regulators of endothelial progenitor cell number in chronic kidney disease.

Wątorek E, Paprocka M, Duś D, Kopeć W, Klinger M.

Pol Arch Med Wewn. 2011 Sep;121(9):296-301.

32.

Serum levels of proANP and albumin are independent predictors of mortality in the high-risk patients (elderly and diabetics) treated by haemodialysis (HD) and continuous peritoneal dialysis in 4-year prospective observation.

Madziarska K, Weyde W, Gosek K, Kopec W, Penar J, Klak R, Zukowska-Szczechowska E, Krajewska M, Kusztal M, Golebiowski T, Radziszewska D, Klinger M.

Nephrol Dial Transplant. 2010 Nov;25(11):3800-1. doi: 10.1093/ndt/gfq515. Epub 2010 Aug 19. No abstract available.

PMID:
20724300
33.

Plasma and urine leukocyte elastase-alpha1protease inhibitor complex as a marker of early and long-term kidney graft function.

Zynek-Litwin M, Kuzniar J, Marchewka Z, Kopec W, Kusztal M, Patrzalek D, Biecek P, Klinger M.

Nephrol Dial Transplant. 2010 Jul;25(7):2346-51. doi: 10.1093/ndt/gfq041. Epub 2010 Feb 16.

PMID:
20164046
34.
35.

[Toll-like receptors (TLR) in the pathogenesis of kidney diseases].

Kazimierczak K, Kopeć W, Klinger M.

Pol Merkur Lekarski. 2007 Nov;23(137):382-5. Review. Polish.

PMID:
18361325
36.
37.

Total antioxidant status and 8-hydroxy-2'-deoxyguanosine levels in gingival and peripheral blood of periodontitis patients.

Konopka T, Król K, Kopeć W, Gerber H.

Arch Immunol Ther Exp (Warsz). 2007 Nov-Dec;55(6):417-22. Epub 2007 Dec 3.

38.

Activated cells in urine and monocyte chemotactic peptide-1 (MCP-1)--sensitive rejection markers in renal graft recipients.

Dubiński B, Boratyńska M, Kopeć W, Szyber P, Patrzałek D, Klinger M.

Transpl Immunol. 2008 Jan;18(3):203-7. Epub 2007 Sep 24.

PMID:
18047927
39.

The effect of dialysis modality (PD and HD) on cardiac morphology and functions in chronic kidney disease patients at very high cardiovascular risk.

Krajewska M, Kosmala W, Weyde W, Madziarska K, Porazko T, Kopec W, Klak R, Penar J, Kusztal M, Watorek E, Golebiowski T, Klinger M.

Nephrol Dial Transplant. 2008 Feb;23(2):768-9. Epub 2007 Nov 20. No abstract available.

PMID:
18029367
40.

Oxidative DNA damage and total antioxidant status in serum of patients with esophageal squamous cell carcinoma.

Diakowska D, Lewandowski A, Kopeć W, Diakowski W, Chrzanowska T.

Hepatogastroenterology. 2007 Sep;54(78):1701-4.

PMID:
18019698
41.

Elastase deposits in the kidney and urinary elastase excretion in patients with glomerulonephritis--evidence for neutrophil involvement in renal injury.

Kuźniar J, Kuźniar TJ, Marchewka Z, Lembas-Bogaczyk J, Rabczyński J, Kopeć W, Klinger M.

Scand J Urol Nephrol. 2007;41(6):527-34.

PMID:
17853021
42.

[Influence of tobacco smoking and periodontitis on selected factors of oxidative stress].

Konopka T, Król K, Kopeć W.

Wiad Lek. 2006;59(7-8):463-70. Polish.

PMID:
17209340
43.

[Blood and tissue eosinophilia in patient with angioedema caused by inhibitor of angiotensin converting enzyme (ACE)--case report and a view of literature].

Panaszek B, Barg W, Małolepszy J, Kopeć W, Obojski A, Wytrychowski K, Chmielowicz B, Biełous-Wilk A, Rabski M, Basińska M.

Pol Arch Med Wewn. 2003 Nov;110(5):1339-43. Review. Polish.

PMID:
16737005
44.

Expression of cystatin C in clinical human colorectal cancer tissues.

Saleh Y, Sebzda T, Warwas M, Kopec W, Ziólkowska J, Siewinski M.

J Exp Ther Oncol. 2005;5(1):49-53.

PMID:
16416601
45.

Actin content and actin polymerization in hepatoma Morris 5123 tumor bearing rats after treatment with cysteine protease inhibitor and vitamin E.

Sebzda T, Saleh Y, Malicka-Blaszkiewicz M, Nowak D, Siewinski M, Ziolkowski P, Kopec W.

J Exp Ther Oncol. 2005;5(1):23-9.

PMID:
16416598
46.

[Antiphospholipid antibodies in the transplanted kidney pathology].

Kazimierczak K, Kazimierczak I, Kopeć W, Klinger M.

Pol Merkur Lekarski. 2004 Dec;17(102):652-5. Review. Polish.

PMID:
15771144
47.

[IL-1beta and PGE2 production in whole blood and gingival fluid in women with periodontitis and preterm low birth weight].

Konopka T, Rutkowska M, Hirnle L, Kopeć W.

Ginekol Pol. 2004 May;75(5):352-60. Polish.

PMID:
15524408
48.

The secretion of prostaglandin E2 and interleukin 1-beta in women with periodontal diseases and preterm low-birth-weight.

Konopka T, Rutkowska M, Hirnle L, Kopec W, Karolewska E.

Bull Group Int Rech Sci Stomatol Odontol. 2003 Jan-Apr;45(1):18-28.

PMID:
14535055
49.

Analysis of collagen IV and fibronectin in blood and urine in evaluation of nephrotic fibrosis in children with chronic glomerulonephritis.

Kiliś-Pstrusińska K, Wikiera-Magott I, Zwolińska D, Kopeć W, Rzeszutko M.

Med Sci Monit. 2002 Oct;8(10):CR713-9.

PMID:
12388925
50.

[Endothelin, endothelial cells and von Willebrand factor in peripheral blood of asthmatic patients].

Krasnowska M, Nittner-Marszalska M, Krasnowski R, Kopeć W.

Pol Merkur Lekarski. 2002 Jun;12(72):445-8. Polish.

PMID:
12362657

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