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Items: 25

1.

Selectivity, efficacy and toxicity studies of UCCB01-144, a dimeric neuroprotective PSD-95 inhibitor.

Bach A, Clausen BH, Kristensen LK, Andersen MG, Ellman DG, Hansen PBL, Hasseldam H, Heitz M, Özcelik D, Tuck EJ, Kopanitsa MV, Grant SGN, Lykke-Hartmann K, Johansen FF, Lambertsen KL, Strømgaard K.

Neuropharmacology. 2019 May 15;150:100-111. doi: 10.1016/j.neuropharm.2019.02.035. Epub 2019 Mar 2.

PMID:
30836092
2.

The Developmental Shift of NMDA Receptor Composition Proceeds Independently of GluN2 Subunit-Specific GluN2 C-Terminal Sequences.

McKay S, Ryan TJ, McQueen J, Indersmitten T, Marwick KFM, Hasel P, Kopanitsa MV, Baxter PS, Martel MA, Kind PC, Wyllie DJA, O'Dell TJ, Grant SGN, Hardingham GE, Komiyama NH.

Cell Rep. 2018 Oct 23;25(4):841-851.e4. doi: 10.1016/j.celrep.2018.09.089.

3.

Impaired Performance of the Q175 Mouse Model of Huntington's Disease in the Touch Screen Paired Associates Learning Task.

Piiponniemi TO, Parkkari T, Heikkinen T, Puoliväli J, Park LC, Cachope R, Kopanitsa MV.

Front Behav Neurosci. 2018 Oct 2;12:226. doi: 10.3389/fnbeh.2018.00226. eCollection 2018.

4.

Architecture of the Mouse Brain Synaptome.

Zhu F, Cizeron M, Qiu Z, Benavides-Piccione R, Kopanitsa MV, Skene NG, Koniaris B, DeFelipe J, Fransén E, Komiyama NH, Grant SGN.

Neuron. 2018 Aug 22;99(4):781-799.e10. doi: 10.1016/j.neuron.2018.07.007. Epub 2018 Aug 2.

5.

Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1+/- mice.

Kopanitsa MV, Gou G, Afinowi NO, Bayés À, Grant SGN, Komiyama NH.

Pharmacol Rep. 2018 Aug;70(4):777-783. doi: 10.1016/j.pharep.2018.02.021. Epub 2018 Jun 23.

PMID:
29940508
6.

Enhanced cognition and dysregulated hippocampal synaptic physiology in mice with a heterozygous deletion of PSD-95.

Horner AE, McLaughlin CL, Afinowi NO, Bussey TJ, Saksida LM, Komiyama NH, Grant SGN, Kopanitsa MV.

Eur J Neurosci. 2018 Jan;47(2):164-176. doi: 10.1111/ejn.13792. Epub 2018 Jan 10.

7.

Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence.

Fernández E, Collins MO, Frank RAW, Zhu F, Kopanitsa MV, Nithianantharajah J, Lemprière SA, Fricker D, Elsegood KA, McLaughlin CL, Croning MDR, Mclean C, Armstrong JD, Hill WD, Deary IJ, Cencelli G, Bagni C, Fromer M, Purcell SM, Pocklington AJ, Choudhary JS, Komiyama NH, Grant SGN.

Cell Rep. 2017 Oct 17;21(3):679-691. doi: 10.1016/j.celrep.2017.09.045.

8.

Acquisition and reversal of visual discrimination learning in APPSwDI/Nos2-/- (CVN) mice.

Piiponniemi TO, Bragge T, Vauhkonen EE, Vartiainen P, Puoliväli JT, Sweeney PJ, Kopanitsa MV.

Neurosci Lett. 2017 May 22;650:126-133. doi: 10.1016/j.neulet.2017.04.049. Epub 2017 Apr 26.

9.

Haploinsufficiency of EHMT1 improves pattern separation and increases hippocampal cell proliferation.

Benevento M, Oomen CA, Horner AE, Amiri H, Jacobs T, Pauwels C, Frega M, Kleefstra T, Kopanitsa MV, Grant SG, Bussey TJ, Saksida LM, Van der Zee CE, van Bokhoven H, Glennon JC, Kasri NN.

Sci Rep. 2017 Jan 10;7:40284. doi: 10.1038/srep40284.

10.

PSD95 nanoclusters are postsynaptic building blocks in hippocampus circuits.

Broadhead MJ, Horrocks MH, Zhu F, Muresan L, Benavides-Piccione R, DeFelipe J, Fricker D, Kopanitsa MV, Duncan RR, Klenerman D, Komiyama NH, Lee SF, Grant SG.

Sci Rep. 2016 Apr 25;6:24626. doi: 10.1038/srep24626.

11.

Evolution of GluN2A/B cytoplasmic domains diversified vertebrate synaptic plasticity and behavior.

Ryan TJ, Kopanitsa MV, Indersmitten T, Nithianantharajah J, Afinowi NO, Pettit C, Stanford LE, Sprengel R, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG, Komiyama NH.

Nat Neurosci. 2013 Jan;16(1):25-32. doi: 10.1038/nn.3277. Epub 2012 Dec 2. Erratum in: Nat Neurosci. 2013 Dec;16(12):1908.

12.

Hippocampal dysfunction in the Euchromatin histone methyltransferase 1 heterozygous knockout mouse model for Kleefstra syndrome.

Balemans MC, Kasri NN, Kopanitsa MV, Afinowi NO, Ramakers G, Peters TA, Beynon AJ, Janssen SM, van Summeren RC, Eeftens JM, Eikelenboom N, Benevento M, Tachibana M, Shinkai Y, Kleefstra T, van Bokhoven H, Van der Zee CE.

Hum Mol Genet. 2013 Mar 1;22(5):852-66. doi: 10.1093/hmg/dds490. Epub 2012 Nov 21.

PMID:
23175442
13.

TNiK is required for postsynaptic and nuclear signaling pathways and cognitive function.

Coba MP, Komiyama NH, Nithianantharajah J, Kopanitsa MV, Indersmitten T, Skene NG, Tuck EJ, Fricker DG, Elsegood KA, Stanford LE, Afinowi NO, Saksida LM, Bussey TJ, O'Dell TJ, Grant SG.

J Neurosci. 2012 Oct 3;32(40):13987-99. doi: 10.1523/JNEUROSCI.2433-12.2012.

14.

Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.

Fernández E, Collins MO, Uren RT, Kopanitsa MV, Komiyama NH, Croning MD, Zografos L, Armstrong JD, Choudhary JS, Grant SG.

Mol Syst Biol. 2009;5:269. doi: 10.1038/msb.2009.27. Epub 2009 May 19.

15.

Neurotransmitters drive combinatorial multistate postsynaptic density networks.

Coba MP, Pocklington AJ, Collins MO, Kopanitsa MV, Uren RT, Swamy S, Croning MD, Choudhary JS, Grant SG.

Sci Signal. 2009 Apr 28;2(68):ra19. doi: 10.1126/scisignal.2000102.

16.

Kinase networks integrate profiles of N-methyl-D-aspartate receptor-mediated gene expression in hippocampus.

Coba MP, Valor LM, Kopanitsa MV, Afinowi NO, Grant SG.

J Biol Chem. 2008 Dec 5;283(49):34101-7. doi: 10.1074/jbc.M804951200. Epub 2008 Sep 23.

17.
18.

Modulation of GABA(A) receptor-mediated currents by benzophenone derivatives in isolated rat Purkinje neurones.

Kopanitsa MV, Yakubovska LM, Rudenko OP, Krishtal OA.

Neuropharmacology. 2002 Sep;43(4):764-77.

PMID:
12367621
19.

Pharmacokinetics of ethanol in mice with different alcohol motivation.

Golovenko NY, Zhuk MS, Zin'kovskii VG, Zhuk OV, Kopanitsa MV.

Bull Exp Biol Med. 2001 Sep;132(3):852-5.

PMID:
11740576
20.

Modulation of GABAA receptor-mediated currents by phenazepam and its metabolites.

Kopanitsa MV, Zhuk OV, Zinkovsky VG, Krishtal OA.

Naunyn Schmiedebergs Arch Pharmacol. 2001 Jul;364(1):1-8.

PMID:
11485032
21.

Inhibitory action of ambocarb on voltage-operated sodium channels in rat isolated hippocampal pyramidal neurons.

Kopanitsa MV, Krishtal OA, Komissarov IV.

Clin Exp Pharmacol Physiol. 2000 Jan-Feb;27(1-2):46-54.

PMID:
10696528
22.

Enhancement of glutamate release uncovers spillover-mediated transmission by N-methyl-D-aspartate receptors in the rat hippocampus.

Lozovaya NA, Kopanitsa MV, Boychuk YA, Krishtal OA.

Neuroscience. 1999;91(4):1321-30.

PMID:
10391439
23.

Kava extract ingredients, (+)-methysticin and (+/-)-kavain inhibit voltage-operated Na(+)-channels in rat CA1 hippocampal neurons.

Magura EI, Kopanitsa MV, Gleitz J, Peters T, Krishtal OA.

Neuroscience. 1997 Nov;81(2):345-51. Erratum in: Neuroscience 1998 May;84(1):323.

PMID:
9300426
24.

Capsaicin blocks Ca2+ channels in isolated rat trigeminal and hippocampal neurones.

Kopanitsa MV, Panchenko VA, Magura EI, Lishko PV, Krishtal OA.

Neuroreport. 1995 Nov 27;6(17):2338-40.

PMID:
8747149

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