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Items: 1 to 50 of 298

1.

Effect of reinforced, targeted in-person education using the Jessa Atrial fibrillation Knowledge Questionnaire in patients with atrial fibrillation: A randomized controlled trial.

Desteghe L, Engelhard L, Vijgen J, Koopman P, Dilling-Boer D, Schurmans J, Delesie M, Dendale P, Heidbuchel H.

Eur J Cardiovasc Nurs. 2018 Oct 17:1474515118804353. doi: 10.1177/1474515118804353. [Epub ahead of print]

PMID:
30328701
2.

Retinoic Acid Antagonizes Testis Development in Mice.

Bowles J, Feng CW, Ineson J, Miles K, Spiller CM, Harley VR, Sinclair AH, Koopman P.

Cell Rep. 2018 Jul 31;24(5):1330-1341. doi: 10.1016/j.celrep.2018.06.111.

3.

Mutant NR5A1/SF-1 in patients with disorders of sex development shows defective activation of the SOX9 TESCO enhancer.

Sreenivasan R, Ludbrook L, Fisher B, Declosmenil F, Knower KC, Croft B, Bird AD, Ryan J, Bashamboo A, Sinclair AH, Koopman P, McElreavey K, Poulat F, Harley VR.

Hum Mutat. 2018 Aug 1. doi: 10.1002/humu.23603. [Epub ahead of print]

PMID:
30067310
4.

Transcriptomic analysis of mRNA expression and alternative splicing during mouse sex determination.

Zhao L, Wang C, Lehman ML, He M, An J, Svingen T, Spiller CM, Ng ET, Nelson CC, Koopman P.

Mol Cell Endocrinol. 2018 Dec 15;478:84-96. doi: 10.1016/j.mce.2018.07.010. Epub 2018 Jul 24.

PMID:
30053582
5.

Effectiveness and usability of an online tailored education platform for atrial fibrillation patients undergoing a direct current cardioversion or pulmonary vein isolation.

Desteghe L, Germeys J, Vijgen J, Koopman P, Dilling-Boer D, Schurmans J, Delesie M, Dendale P, Heidbuchel H.

Int J Cardiol. 2018 Dec 1;272:123-129. doi: 10.1016/j.ijcard.2018.07.065. Epub 2018 Jul 17.

PMID:
30049498
6.

Innovation in dental education: The "On-the-Fly" approach to simultaneous development, implementation and evidence collection.

de Boer IR, Bakker DR, Serrano CM, Koopman P, Wesselink PR, Vervoorn JM.

Eur J Dent Educ. 2018 Nov;22(4):215-222. doi: 10.1111/eje.12331. Epub 2018 Mar 1.

PMID:
29498178
7.

A predominant cardiac phenotype of Anderson-Fabry disease in presence of a MYBPC3 gene mutation and a LAMA4 gene mutation.

Laenens D, Koopman P, Cools T.

Acta Cardiol. 2018 Feb 7:1-2. doi: 10.1080/00015385.2018.1433458. [Epub ahead of print] No abstract available.

PMID:
29415625
8.

Telemonitoring-based feedback improves adherence to non-vitamin K antagonist oral anticoagulants intake in patients with atrial fibrillation.

Desteghe L, Vijgen J, Koopman P, Dilling-Boer D, Schurmans J, Dendale P, Heidbuchel H.

Eur Heart J. 2018 Apr 21;39(16):1394-1403. doi: 10.1093/eurheartj/ehx762.

PMID:
29300888
9.

SOX30 is required for male fertility in mice.

Feng CA, Spiller C, Merriner DJ, O'Bryan MK, Bowles J, Koopman P.

Sci Rep. 2017 Dec 15;7(1):17619. doi: 10.1038/s41598-017-17854-5.

10.

Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.

Bagheri-Fam S, Bird AD, Zhao L, Ryan JM, Yong M, Wilhelm D, Koopman P, Eswarakumar VP, Harley VR.

Endocrinology. 2017 Nov 1;158(11):3832-3843. doi: 10.1210/en.2017-00674.

11.

RNA binding protein Musashi-2 regulates PIWIL1 and TBX1 in mouse spermatogenesis.

Sutherland JM, Sobinoff AP, Fraser BA, Redgrove KA, Siddall NA, Koopman P, Hime GR, McLaughlin EA.

J Cell Physiol. 2018 Apr;233(4):3262-3273. doi: 10.1002/jcp.26168. Epub 2017 Oct 4.

PMID:
28884822
12.

Sex Determination in the Mammalian Germline.

Spiller C, Koopman P, Bowles J.

Annu Rev Genet. 2017 Nov 27;51:265-285. doi: 10.1146/annurev-genet-120215-035449. Epub 2017 Aug 30. Review.

PMID:
28853925
13.

The Health Buddies App as a Novel Tool to Improve Adherence and Knowledge in Atrial Fibrillation Patients: A Pilot Study.

Desteghe L, Kluts K, Vijgen J, Koopman P, Dilling-Boer D, Schurmans J, Dendale P, Heidbuchel H.

JMIR Mhealth Uhealth. 2017 Jul 19;5(7):e98. doi: 10.2196/mhealth.7420.

14.

Small-Molecule Inhibitors of the SOX18 Transcription Factor.

Fontaine F, Overman J, Moustaqil M, Mamidyala S, Salim A, Narasimhan K, Prokoph N, Robertson AAB, Lua L, Alexandrov K, Koopman P, Capon RJ, Sierecki E, Gambin Y, Jauch R, Cooper MA, Zuegg J, Francois M.

Cell Chem Biol. 2017 Mar 16;24(3):346-359. doi: 10.1016/j.chembiol.2017.01.003. Epub 2017 Feb 2.

15.

Reduced Activity of SRY and its Target Enhancer Sox9-TESCO in a Mouse Species with X*Y Sex Reversal.

Zhao L, Quinn A, Ng ET, Veyrunes F, Koopman P.

Sci Rep. 2017 Feb 3;7:41378. doi: 10.1038/srep41378.

16.

Correction: Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

Gonen N, Quinn A, O'Neill HC, Koopman P, Lovell-Badge R.

PLoS Genet. 2017 Feb 1;13(2):e1006584. doi: 10.1371/journal.pgen.1006584. eCollection 2017 Feb.

17.

Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice.

Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, Zuegg J, Robertson AA, Holmes K, Salim AA, Mamidyala S, Butler MS, Robinson AS, Lesieur E, Johnston W, Alexandrov K, Black BL, Hogan BM, De Val S, Capon RJ, Carroll JS, Bailey TL, Koopman P, Jauch R, Smyth MJ, Cooper MA, Gambin Y, Francois M.

Elife. 2017 Jan 31;6. pii: e21221. doi: 10.7554/eLife.21221.

18.

SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice.

Zhao L, Arsenault M, Ng ET, Longmuss E, Chau TC, Hartwig S, Koopman P.

Dev Biol. 2017 Mar 1;423(1):46-56. doi: 10.1016/j.ydbio.2017.01.013. Epub 2017 Jan 21.

19.

Mice Lacking Hbp1 Function Are Viable and Fertile.

Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P.

PLoS One. 2017 Jan 20;12(1):e0170576. doi: 10.1371/journal.pone.0170576. eCollection 2017.

20.

Normal Levels of Sox9 Expression in the Developing Mouse Testis Depend on the TES/TESCO Enhancer, but This Does Not Act Alone.

Gonen N, Quinn A, O'Neill HC, Koopman P, Lovell-Badge R.

PLoS Genet. 2017 Jan 3;13(1):e1006520. doi: 10.1371/journal.pgen.1006520. eCollection 2017 Jan. Erratum in: PLoS Genet. 2017 Feb 1;13(2):e1006584.

21.

Disorders of sex development: insights from targeted gene sequencing of a large international patient cohort.

Eggers S, Sadedin S, van den Bergen JA, Robevska G, Ohnesorg T, Hewitt J, Lambeth L, Bouty A, Knarston IM, Tan TY, Cameron F, Werther G, Hutson J, O'Connell M, Grover SR, Heloury Y, Zacharin M, Bergman P, Kimber C, Brown J, Webb N, Hunter MF, Srinivasan S, Titmuss A, Verge CF, Mowat D, Smith G, Smith J, Ewans L, Shalhoub C, Crock P, Cowell C, Leong GM, Ono M, Lafferty AR, Huynh T, Visser U, Choong CS, McKenzie F, Pachter N, Thompson EM, Couper J, Baxendale A, Gecz J, Wheeler BJ, Jefferies C, MacKenzie K, Hofman P, Carter P, King RI, Krausz C, van Ravenswaaij-Arts CM, Looijenga L, Drop S, Riedl S, Cools M, Dawson A, Juniarto AZ, Khadilkar V, Khadilkar A, Bhatia V, Dũng VC, Atta I, Raza J, Thi Diem Chi N, Hao TK, Harley V, Koopman P, Warne G, Faradz S, Oshlack A, Ayers KL, Sinclair AH.

Genome Biol. 2016 Nov 29;17(1):243.

22.

Clinical benefit of atrio-ventricular delay optimization in patients with a dual-chamber pacemaker: a pilot study.

Cools T, Daerden T, Herbots L, Geukens R, Verwerft J, Koopman P, Dilling-Boer D, Hansen D, Vranckx P, Dendale P.

Acta Cardiol. 2016 Jun;71(3):257-65. doi: 10.2143/AC.71.3.3152085. No abstract available.

PMID:
27594120
23.

Knowledge gaps in patients with atrial fibrillation revealed by a new validated knowledge questionnaire.

Desteghe L, Engelhard L, Raymaekers Z, Kluts K, Vijgen J, Dilling-Boer D, Koopman P, Schurmans J, Dendale P, Heidbuchel H.

Int J Cardiol. 2016 Nov 15;223:906-914. doi: 10.1016/j.ijcard.2016.08.303. Epub 2016 Aug 21.

PMID:
27589038
24.

SOX9 regulates expression of the male fertility gene Ets variant factor 5 (ETV5) during mammalian sex development.

Alankarage D, Lavery R, Svingen T, Kelly S, Ludbrook L, Bagheri-Fam S, Koopman P, Harley V.

Int J Biochem Cell Biol. 2016 Oct;79:41-51. doi: 10.1016/j.biocel.2016.08.005. Epub 2016 Aug 4.

PMID:
27498191
25.

Of sex and determination: marking 25 years of Randy, the sex-reversed mouse.

Koopman P, Sinclair A, Lovell-Badge R.

Development. 2016 May 15;143(10):1633-7. doi: 10.1242/dev.137372.

26.

The Curious World of Gonadal Development in Mammals.

Koopman P.

Curr Top Dev Biol. 2016;116:537-45. doi: 10.1016/bs.ctdb.2015.12.009. Epub 2016 Feb 17. Review.

PMID:
26970639
27.

Performance of handheld electrocardiogram devices to detect atrial fibrillation in a cardiology and geriatric ward setting.

Desteghe L, Raymaekers Z, Lutin M, Vijgen J, Dilling-Boer D, Koopman P, Schurmans J, Vanduynhoven P, Dendale P, Heidbuchel H.

Europace. 2017 Jan;19(1):29-39. doi: 10.1093/europace/euw025. Epub 2016 Feb 17.

PMID:
26893496
28.

ALDH1A1 provides a source of meiosis-inducing retinoic acid in mouse fetal ovaries.

Bowles J, Feng CW, Miles K, Ineson J, Spiller C, Koopman P.

Nat Commun. 2016 Feb 19;7:10845. doi: 10.1038/ncomms10845.

29.

Intrauterine Exposure to Paracetamol and Aniline Impairs Female Reproductive Development by Reducing Follicle Reserves and Fertility.

Holm JB, Mazaud-Guittot S, Danneskiold-Samsøe NB, Chalmey C, Jensen B, Nørregård MM, Hansen CH, Styrishave B, Svingen T, Vinggaard AM, Koch HM, Bowles J, Koopman P, Jégou B, Kristiansen K, Kristensen DM.

Toxicol Sci. 2016 Mar;150(1):178-89. doi: 10.1093/toxsci/kfv332. Epub 2016 Jan 5.

PMID:
26732887
30.

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors.

Spiller CM, Gillis AJ, Burnet G, Stoop H, Koopman P, Bowles J, Looijenga LH.

Mol Oncol. 2016 Apr;10(4):526-37. doi: 10.1016/j.molonc.2015.11.003. Epub 2015 Nov 18.

31.

Germ cells influence cord formation and Leydig cell gene expression during mouse testis development.

Rios-Rojas C, Spiller C, Bowles J, Koopman P.

Dev Dyn. 2016 Apr;245(4):433-44. doi: 10.1002/dvdy.24371. Epub 2016 Jan 8.

32.

Conservation analysis of sequences flanking the testis-determining gene Sry in 17 mammalian species.

Larney C, Bailey TL, Koopman P.

BMC Dev Biol. 2015 Oct 6;15:34. doi: 10.1186/s12861-015-0085-6.

33.

FGFR2 mutation in 46,XY sex reversal with craniosynostosis.

Bagheri-Fam S, Ono M, Li L, Zhao L, Ryan J, Lai R, Katsura Y, Rossello FJ, Koopman P, Scherer G, Bartsch O, Eswarakumar JV, Harley VR.

Hum Mol Genet. 2015 Dec 1;24(23):6699-710. doi: 10.1093/hmg/ddv374. Epub 2015 Sep 11.

34.

ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation.

Wainwright EN, Wilhelm D, Combes AN, Little MH, Koopman P.

Dev Biol. 2015 Aug 15;404(2):88-102. doi: 10.1016/j.ydbio.2015.05.023. Epub 2015 Jun 23.

35.

Purification and Transcriptomic Analysis of Mouse Fetal Leydig Cells Reveals Candidate Genes for Specification of Gonadal Steroidogenic Cells.

McClelland KS, Bell K, Larney C, Harley VR, Sinclair AH, Oshlack A, Koopman P, Bowles J.

Biol Reprod. 2015 Jun;92(6):145. doi: 10.1095/biolreprod.115.128918. Epub 2015 Apr 8.

PMID:
25855264
36.

RNA binding protein Musashi-1 directly targets Msi2 and Erh during early testis germ cell development and interacts with IPO5 upon translocation to the nucleus.

Sutherland JM, Sobinoff AP, Fraser BA, Redgrove KA, Davidson TL, Siddall NA, Koopman P, Hime GR, McLaughlin EA.

FASEB J. 2015 Jul;29(7):2759-68. doi: 10.1096/fj.14-265868. Epub 2015 Mar 17.

PMID:
25782991
37.

Female-to-male sex reversal in mice caused by transgenic overexpression of Dmrt1.

Zhao L, Svingen T, Ng ET, Koopman P.

Development. 2015 Mar 15;142(6):1083-8. doi: 10.1242/dev.122184. Epub 2015 Feb 27.

38.

Specific interaction with the nuclear transporter importin α2 can modulate paraspeckle protein 1 delivery to nuclear paraspeckles.

Major AT, Hogarth CA, Miyamoto Y, Sarraj MA, Smith CL, Koopman P, Kurihara Y, Jans DA, Loveland KL.

Mol Biol Cell. 2015 Apr 15;26(8):1543-58. doi: 10.1091/mbc.E14-01-0678. Epub 2015 Feb 18.

39.

Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos.

McClelland KS, Wainwright EN, Bowles J, Koopman P.

PLoS One. 2015 Jan 28;10(1):e0114932. doi: 10.1371/journal.pone.0114932. eCollection 2015.

40.

On the role of germ cells in mammalian gonad development: quiet passengers or back-seat drivers?

Rios-Rojas C, Bowles J, Koopman P.

Reproduction. 2015 Apr;149(4):R181-91. doi: 10.1530/REP-14-0663. Epub 2015 Jan 27. Review.

PMID:
25628441
41.

Primary cilia function regulates the length of the embryonic trunk axis and urogenital field in mice.

Wainwright EN, Svingen T, Ng ET, Wicking C, Koopman P.

Dev Biol. 2014 Nov 15;395(2):342-54. doi: 10.1016/j.ydbio.2014.08.037. Epub 2014 Sep 16.

42.

Whole exome sequencing combined with linkage analysis identifies a novel 3 bp deletion in NR5A1.

Eggers S, Smith KR, Bahlo M, Looijenga LH, Drop SL, Juniarto ZA, Harley VR, Koopman P, Faradz SM, Sinclair AH.

Eur J Hum Genet. 2015 Apr;23(4):486-93. doi: 10.1038/ejhg.2014.130. Epub 2014 Aug 6.

43.

Structure-function analysis of mouse Sry reveals dual essential roles of the C-terminal polyglutamine tract in sex determination.

Zhao L, Ng ET, Davidson TL, Longmuss E, Urschitz J, Elston M, Moisyadi S, Bowles J, Koopman P.

Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):11768-73. doi: 10.1073/pnas.1400666111. Epub 2014 Jul 29.

44.

A piggyBac transposon- and gateway-enhanced system for efficient BAC transgenesis.

Zhao L, Ng ET, Koopman P.

Dev Dyn. 2014 Sep;243(9):1086-94. doi: 10.1002/dvdy.24153. Epub 2014 Jun 25. Erratum in: Dev Dyn. 2014 Nov;243(11):1499-500.

45.

Switching on sex: transcriptional regulation of the testis-determining gene Sry.

Larney C, Bailey TL, Koopman P.

Development. 2014 Jun;141(11):2195-205. doi: 10.1242/dev.107052. Review.

46.

A site-specific, single-copy transgenesis strategy to identify 5' regulatory sequences of the mouse testis-determining gene Sry.

Quinn A, Kashimada K, Davidson TL, Ng ET, Chawengsaksophak K, Bowles J, Koopman P.

PLoS One. 2014 Apr 17;9(4):e94813. doi: 10.1371/journal.pone.0094813. eCollection 2014.

47.

Developmental expression of Musashi-1 and Musashi-2 RNA-binding proteins during spermatogenesis: analysis of the deleterious effects of dysregulated expression.

Sutherland JM, Fraser BA, Sobinoff AP, Pye VJ, Davidson TL, Siddall NA, Koopman P, Hime GR, McLaughlin EA.

Biol Reprod. 2014 May 1;90(5):92. doi: 10.1095/biolreprod.113.115261. Print 2014 May.

PMID:
24671879
48.

FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice.

Takasawa K, Kashimada K, Pelosi E, Takagi M, Morio T, Asahara H, Schlessinger D, Mizutani S, Koopman P.

FASEB J. 2014 May;28(5):2020-8. doi: 10.1096/fj.13-246108. Epub 2014 Jan 22.

49.

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo.

Bowles J, Secker G, Nguyen C, Kazenwadel J, Truong V, Frampton E, Curtis C, Skoczylas R, Davidson TL, Miura N, Hong YK, Koopman P, Harvey NL, François M.

Dev Biol. 2014 Feb 1;386(1):25-33. doi: 10.1016/j.ydbio.2013.12.008. Epub 2013 Dec 19.

50.

VEGFD regulates blood vascular development by modulating SOX18 activity.

Duong T, Koltowska K, Pichol-Thievend C, Le Guen L, Fontaine F, Smith KA, Truong V, Skoczylas R, Stacker SA, Achen MG, Koopman P, Hogan BM, Francois M.

Blood. 2014 Feb 13;123(7):1102-12. doi: 10.1182/blood-2013-04-495432. Epub 2013 Nov 22.

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