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Items: 1 to 50 of 165

1.

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.

Yurgelun MB, Chittenden AB, Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Qian ZR, Welch MW, Brais LK, Da Silva A, Bui JL, Yuan C, Li T, Li W, Masuda A, Gu M, Bullock AJ, Chang DT, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar MD, Wollison BM, Khalaf N, Perez K, Syngal S, Aguirre AJ, Hahn WC, Meyerson ML, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC, Nowak JA, Wolpin BM.

Genet Med. 2018 Jul 2. doi: 10.1038/s41436-018-0009-5. [Epub ahead of print]

PMID:
29961768
2.

Comparing Ablative Modalities for Hepatocellular Carcinoma: Cautions in Interpreting Big Data.

Smith GL, Das P, Herman JM, Koay EJ, Koong AC, Grossberg A, Ludmir E.

J Clin Oncol. 2018 Jun 26:JCO2018785428. doi: 10.1200/JCO.2018.78.5428. [Epub ahead of print] No abstract available.

PMID:
29945520
3.

Altered exocrine function can drive adipose wasting in early pancreatic cancer.

Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG.

Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7. Epub 2018 Jun 20.

PMID:
29925948
4.

18F-EF5 PET-based Imageable Hypoxia Predicts Local Recurrence in Tumors Treated With Highly Conformal Radiation Therapy.

Qian Y, Von Eyben R, Liu Y, Chin FT, Miao Z, Apte S, Carter JN, Binkley MS, Pollom EL, Harris JP, Prionas ND, Kissel M, Simmons A, Diehn M, Shultz DB, Brown JM, Maxim PG, Koong AC, Graves EE, Loo BW Jr.

Int J Radiat Oncol Biol Phys. 2018 Apr 18. pii: S0360-3016(18)30596-0. doi: 10.1016/j.ijrobp.2018.03.045. [Epub ahead of print]

PMID:
29859786
5.

Management of Borderline Resectable Pancreatic Cancer.

Toesca DAS, Koong AJ, Poultsides GA, Visser BC, Haraldsdottir S, Koong AC, Chang DT.

Int J Radiat Oncol Biol Phys. 2018 Apr 1;100(5):1155-1174. doi: 10.1016/j.ijrobp.2017.12.287. Review.

PMID:
29722658
6.

High lymphocyte count during neoadjuvant chemoradiotherapy is associated with improved pathologic complete response in esophageal cancer.

Fang P, Jiang W, Davuluri R, Xu C, Krishnan S, Mohan R, Koong AC, Hsu CC, Lin SH.

Radiother Oncol. 2018 Mar 9. pii: S0167-8140(18)30117-8. doi: 10.1016/j.radonc.2018.02.025. [Epub ahead of print]

PMID:
29530432
7.

Present developments in reaching an international consensus for a model-based approach to particle beam therapy.

Prayongrat A, Umegaki K, van der Schaaf A, Koong AC, Lin SH, Whitaker T, McNutt T, Matsufuji N, Graves E, Mizuta M, Ogawa K, Date H, Moriwaki K, Ito YM, Kobashi K, Dekura Y, Shimizu S, Shirato H.

J Radiat Res. 2018 Mar 1;59(suppl_1):i72-i76. doi: 10.1093/jrr/rry008.

8.

A Human Genome-Wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1α-XBP1 Activation.

Yang Z, Zhang J, Jiang D, Khatri P, Solow-Cordero DE, Toesca DAS, Koumenis C, Denko NC, Giaccia AJ, Le QT, Koong AC.

Mol Cancer Res. 2018 May;16(5):745-753. doi: 10.1158/1541-7786.MCR-17-0307. Epub 2018 Feb 9.

PMID:
29440447
9.

Strategies for prediction and mitigation of radiation-induced liver toxicity.

Toesca DAS, Ibragimov B, Koong AJ, Xing L, Koong AC, Chang DT.

J Radiat Res. 2018 Mar 1;59(suppl_1):i40-i49. doi: 10.1093/jrr/rrx104.

10.

Inhibition of IRE1 results in decreased scar formation.

Boyko TV, Bam R, Jiang D, Wang Z, Bhatia N, Tran MC, Longaker MT, Koong AC, Yang GP.

Wound Repair Regen. 2017 Nov;25(6):964-971. doi: 10.1111/wrr.12603. Epub 2018 Feb 6.

PMID:
29316036
11.

Multiplex Proximity Ligation Assay to Identify Potential Prognostic Biomarkers for Improved Survival in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy.

Rao AD, Liu Y, von Eyben R, Hsu CC, Hu C, Rosati LM, Parekh A, Ng K, Hacker-Prietz A, Zheng L, Pawlik TM, Laheru DA, Jaffee EM, Weiss MJ, Le DT, Hruban RH, De Jesus-Acosta A, Wolfgang CL, Narang AK, Chang DT, Koong AC, Herman JM.

Int J Radiat Oncol Biol Phys. 2018 Feb 1;100(2):486-489. doi: 10.1016/j.ijrobp.2017.10.001. Epub 2017 Oct 12.

PMID:
29157747
12.

Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma.

Qian ZR, Rubinson DA, Nowak JA, Morales-Oyarvide V, Dunne RF, Kozak MM, Welch MW, Brais LK, Da Silva A, Li T, Li W, Masuda A, Yang J, Shi Y, Gu M, Masugi Y, Bui J, Zellers CL, Yuan C, Babic A, Khalaf N, Aguirre A, Ng K, Miksad RA, Bullock AJ, Chang DT, Tseng JF, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar M, Wollison B, Laing A, Hahn WC, Meyerson M, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC, Wolpin BM.

JAMA Oncol. 2018 Mar 8;4(3):e173420. doi: 10.1001/jamaoncol.2017.3420. Epub 2018 Mar 8.

PMID:
29098284
13.

Nonoperative Management of Rectal Cancer: A Modern Perspective.

Qian Y, Chin AL, Toesca DAS, Koong AC, Chang DT.

Oncology (Williston Park). 2017 Oct 15;31(10):e13-e22. Review.

14.

Impact of Intensity-Modulated Radiotherapy on Health Care Costs of Patients With Anal Squamous Cell Carcinoma.

Chin AL, Pollom EL, Qian Y, Koong AC, Chang DT.

J Oncol Pract. 2017 Dec;13(12):e992-e1001. doi: 10.1200/JOP.2017.024810. Epub 2017 Oct 16.

PMID:
29035618
15.

A p53 Super-tumor Suppressor Reveals a Tumor Suppressive p53-Ptpn14-Yap Axis in Pancreatic Cancer.

Mello SS, Valente LJ, Raj N, Seoane JA, Flowers BM, McClendon J, Bieging-Rolett KT, Lee J, Ivanochko D, Kozak MM, Chang DT, Longacre TA, Koong AC, Arrowsmith CH, Kim SK, Vogel H, Wood LD, Hruban RH, Curtis C, Attardi LD.

Cancer Cell. 2017 Oct 9;32(4):460-473.e6. doi: 10.1016/j.ccell.2017.09.007.

PMID:
29017057
16.

Lymph node metastases in resected pancreatic ductal adenocarcinoma: predictors of disease recurrence and survival.

Morales-Oyarvide V, Rubinson DA, Dunne RF, Kozak MM, Bui JL, Yuan C, Qian ZR, Babic A, Da Silva A, Nowak JA, Khalaf N, Brais LK, Welch MW, Zellers CL, Ng K, Chang DT, Miksad RA, Bullock AJ, Tseng JF, Swanson RS, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Hornick JL, Ogino S, Fuchs CS, Hezel AF, Koong AC, Wolpin BM.

Br J Cancer. 2017 Dec 5;117(12):1874-1882. doi: 10.1038/bjc.2017.349. Epub 2017 Oct 5.

PMID:
28982112
17.

Breathing New Life Into Hypoxia-Targeted Therapies for Non-Small Cell Lung Cancer.

Lin SH, Koong AC.

J Natl Cancer Inst. 2018 Jan 1;110(1). doi: 10.1093/jnci/djx163. No abstract available.

PMID:
28922792
18.

BLIMP1 Induces Transient Metastatic Heterogeneity in Pancreatic Cancer.

Chiou SH, Risca VI, Wang GX, Yang D, Grüner BM, Kathiria AS, Ma RK, Vaka D, Chu P, Kozak M, Castellini L, Graves EE, Kim GE, Mourrain P, Koong AC, Giaccia AJ, Winslow MM.

Cancer Discov. 2017 Oct;7(10):1184-1199. doi: 10.1158/2159-8290.CD-17-0250. Epub 2017 Aug 8.

19.

Introduction.

Koong AC, Tepper JE.

Semin Radiat Oncol. 2017 Jul;27(3):189. doi: 10.1016/j.semradonc.2017.03.005. Epub 2017 Mar 18. No abstract available.

PMID:
28577825
20.

Assessment of hepatic function decline after stereotactic body radiation therapy for primary liver cancer.

Toesca DAS, Osmundson EC, von Eyben R, Shaffer JL, Koong AC, Chang DT.

Pract Radiat Oncol. 2017 May - Jun;7(3):173-182. doi: 10.1016/j.prro.2016.10.003. Epub 2016 Oct 17.

PMID:
28343896
21.

Assessing local progression after stereotactic body radiation therapy for unresectable pancreatic adenocarcinoma: CT versus PET.

Toesca DA, Pollom EL, Poullos PD, Flynt L, Cui Y, Quon A, von Eyben R, Koong AC, Chang DT.

Pract Radiat Oncol. 2017 Mar - Apr;7(2):120-125. doi: 10.1016/j.prro.2016.09.002. Epub 2016 Sep 7.

PMID:
28274396
22.

The Impact of Intensity Modulated Radiation Therapy on Hospitalization Outcomes in the SEER-Medicare Population With Anal Squamous Cell Carcinoma.

Pollom EL, Wang G, Harris JP, Koong AC, Bendavid E, Bhattacharya J, Chang DT.

Int J Radiat Oncol Biol Phys. 2017 May 1;98(1):177-185. doi: 10.1016/j.ijrobp.2017.01.006. Epub 2017 Jan 7.

PMID:
28258896
23.

Chemical Space Mimicry for Drug Discovery.

Yuan W, Jiang D, Nambiar DK, Liew LP, Hay MP, Bloomstein J, Lu P, Turner B, Le QT, Tibshirani R, Khatri P, Moloney MG, Koong AC.

J Chem Inf Model. 2017 Apr 24;57(4):875-882. doi: 10.1021/acs.jcim.6b00754. Epub 2017 Apr 3.

24.

ACR Appropriateness Criteria® Resectable Pancreatic Cancer.

Jones WE 3rd, Suh WW, Abdel-Wahab M, Abrams RA, Azad N, Das P, Dragovic J, Goodman KA, Jabbour SK, Konski AA, Koong AC, Kumar R, Lee P, Pawlik TM, Small W Jr, Herman JM; Expert Panel on Radiation OncologyGastrointestinal.

Am J Clin Oncol. 2017 Apr;40(2):109-117. doi: 10.1097/COC.0000000000000370. Review.

PMID:
28230650
25.

Cost-effectiveness of Stereotactic Body Radiation Therapy versus Radiofrequency Ablation for Hepatocellular Carcinoma: A Markov Modeling Study.

Pollom EL, Lee K, Durkee BY, Grade M, Mokhtari DA, Wahl DR, Feng M, Kothary N, Koong AC, Owens DK, Goldhaber-Fiebert J, Chang DT.

Radiology. 2017 May;283(2):460-468. doi: 10.1148/radiol.2016161509. Epub 2017 Jan 3.

26.

Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes.

Jiang D, Turner B, Song J, Li R, Diehn M, Le QT, Khatri P, Koong AC.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.16.00073. Epub 2017 Jul 26.

27.

Reprogramming the immunological microenvironment through radiation and targeting Axl.

Aguilera TA, Rafat M, Castellini L, Shehade H, Kariolis MS, Hui AB, Stehr H, von Eyben R, Jiang D, Ellies LG, Koong AC, Diehn M, Rankin EB, Graves EE, Giaccia AJ.

Nat Commun. 2016 Dec 23;7:13898. doi: 10.1038/ncomms13898.

28.

Perfusion CT measurements predict tumor response in rectal carcinoma.

Kino A, Shaffer J, Maturen KE, Schmiedeskamp H, Koong AC, Chang DT, Fleischmann D, Kamaya A.

Abdom Radiol (NY). 2017 Apr;42(4):1132-1140. doi: 10.1007/s00261-016-0983-5.

PMID:
28008455
29.

Inhibition of the GAS6/AXL pathway augments the efficacy of chemotherapies.

Kariolis MS, Miao YR, Diep A, Nash SE, Olcina MM, Jiang D, Jones DS 2nd, Kapur S, Mathews II, Koong AC, Rankin EB, Cochran JR, Giaccia AJ.

J Clin Invest. 2017 Jan 3;127(1):183-198. doi: 10.1172/JCI85610. Epub 2016 Nov 28.

30.

Does radiotherapy still have a role in unresected biliary tract cancer?

Pollom EL, Alagappan M, Park LS, Whittemore AS, Koong AC, Chang DT.

Cancer Med. 2017 Jan;6(1):129-141. doi: 10.1002/cam4.975. Epub 2016 Nov 28.

31.

Central liver toxicity after SBRT: An expanded analysis and predictive nomogram.

Toesca DA, Osmundson EC, Eyben RV, Shaffer JL, Lu P, Koong AC, Chang DT.

Radiother Oncol. 2017 Jan;122(1):130-136. doi: 10.1016/j.radonc.2016.10.024. Epub 2016 Nov 16.

PMID:
27865544
32.

Identification of Doxorubicin as an Inhibitor of the IRE1α-XBP1 Axis of the Unfolded Protein Response.

Jiang D, Lynch C, Medeiros BC, Liedtke M, Bam R, Tam AB, Yang Z, Alagappan M, Abidi P, Le QT, Giaccia AJ, Denko NC, Niwa M, Koong AC.

Sci Rep. 2016 Sep 16;6:33353. doi: 10.1038/srep33353.

33.

Quantitative Analysis of (18)F-Fluorodeoxyglucose Positron Emission Tomography Identifies Novel Prognostic Imaging Biomarkers in Locally Advanced Pancreatic Cancer Patients Treated With Stereotactic Body Radiation Therapy.

Cui Y, Song J, Pollom E, Alagappan M, Shirato H, Chang DT, Koong AC, Li R.

Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):102-9. doi: 10.1016/j.ijrobp.2016.04.034. Epub 2016 May 7.

PMID:
27511850
34.

ACR Appropriateness Criteria® Borderline and Unresectable Pancreas Cancer.

Expert Panel on Radiation Oncology-Gastrointestinal, Small W Jr, Hayes JP, Suh WW, Abdel-Wahab M, Abrams RA, Azad N, Das P, Dragovic J, Goodman KA, Jabbour SK, Jones WE 3rd, Konski AA, Koong AC, Kumar R, Lee P, Pawlik TM, Herman JM.

Oncology (Williston Park). 2016 Jul;30(7):619-24, 627, 632. Review.

35.

A Multimodal Data Analysis Approach for Targeted Drug Discovery Involving Topological Data Analysis (TDA).

Alagappan M, Jiang D, Denko N, Koong AC.

Adv Exp Med Biol. 2016;899:253-68. doi: 10.1007/978-3-319-26666-4_15.

36.

Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.

Jiang D, Tam AB, Alagappan M, Hay MP, Gupta A, Kozak MM, Solow-Cordero DE, Lum PY, Denko NC, Giaccia AJ, Le QT, Niwa M, Koong AC.

Mol Cancer Ther. 2016 Sep;15(9):2055-65. doi: 10.1158/1535-7163.MCT-15-1023. Epub 2016 Jun 15.

37.

A Novel Biomarker Panel Examining Response to Gemcitabine with or without Erlotinib for Pancreatic Cancer Therapy in NCIC Clinical Trials Group PA.3.

Shultz DB, Pai J, Chiu W, Ng K, Hellendag MG, Heestand G, Chang DT, Tu D, Moore MJ, Parulekar WR, Koong AC.

PLoS One. 2016 Jan 25;11(1):e0147995. doi: 10.1371/journal.pone.0147995. eCollection 2016.

38.

Albumin and Neutrophil-Lymphocyte Ratio (NLR) Predict Survival in Patients With Pancreatic Adenocarcinoma Treated With SBRT.

Alagappan M, Pollom EL, von Eyben R, Kozak MM, Aggarwal S, Poultsides GA, Koong AC, Chang DT.

Am J Clin Oncol. 2018 Mar;41(3):242-247. doi: 10.1097/COC.0000000000000263.

PMID:
26757436
39.

Plant stilbenes induce endoplasmic reticulum stress and their anti-cancer activity can be enhanced by inhibitors of autophagy.

Papandreou I, Verras M, McNeil B, Koong AC, Denko NC.

Exp Cell Res. 2015 Nov 15;339(1):147-53. doi: 10.1016/j.yexcr.2015.10.014. Epub 2015 Oct 17.

40.

Serum Transforming Growth Factor-β1 Change After Neoadjuvant Chemoradiation Therapy Is Associated With Postoperative Pulmonary Complications in Esophageal Cancer Patients Undergoing Combined Modality Therapy.

Lu SL, Hsu FM, Tsai CL, Wu JK, Lee JM, Huang PM, Hsu CH, Koong AC, Chang DT, Cheng JC.

Int J Radiat Oncol Biol Phys. 2015 Dec 1;93(5):1023-31. doi: 10.1016/j.ijrobp.2015.08.035. Epub 2015 Aug 28.

PMID:
26475065
41.

Statin and Metformin Use Prolongs Survival in Patients With Resectable Pancreatic Cancer.

Kozak MM, Anderson EM, von Eyben R, Pai JS, Poultsides GA, Visser BC, Norton JA, Koong AC, Chang DT.

Pancreas. 2016 Jan;45(1):64-70. doi: 10.1097/MPA.0000000000000470.

PMID:
26474429
42.

ACR Appropriateness Criteria® Local Excision in Early Stage Rectal Cancer.

Russo S, Blackstock AW, Herman JM, Abdel-Wahab M, Azad N, Das P, Goodman KA, Hong TS, Jabbour SK, Jones WE 3rd, Konski AA, Koong AC, Kumar R, Rodriguez-Bigas M, Small W Jr, Thomas CR Jr, Suh WW.

Am J Clin Oncol. 2015 Oct;38(5):520-5. doi: 10.1097/COC.0000000000000197. Review.

PMID:
26371522
43.

ACR Appropriateness Criteria® Resectable Stomach Cancer.

Daroui P, Jabbour SK, Herman JM, Abdel-Wahab M, Azad N, Blackstock AW, Das P, Goodman KA, Hong TS, Jones WE 3rd, Kaur H, Konski AA, Koong AC, Kumar R, Pawlik TM, Small W Jr, Thomas CR Jr, Suh WW.

Oncology (Williston Park). 2015 Aug;29(8):595-602, C3. Review.

44.

Treatment Approaches to Locally Advanced Pancreatic Adenocarcinoma.

Pollom EL, Koong AC, Ko AH.

Hematol Oncol Clin North Am. 2015 Aug;29(4):741-59. doi: 10.1016/j.hoc.2015.04.005. Epub 2015 May 30. Review.

PMID:
26226908
45.

Stereotactic body radiation therapy and central liver toxicity: A case report.

Shaffer JL, Osmundson EC, Visser BC, Longacre TA, Koong AC, Chang DT.

Pract Radiat Oncol. 2015 Sep-Oct;5(5):282-285. doi: 10.1016/j.prro.2015.04.011. Epub 2015 Jun 27. No abstract available.

PMID:
26127008
46.

Gastrointestinal Toxicities With Combined Antiangiogenic and Stereotactic Body Radiation Therapy.

Pollom EL, Deng L, Pai RK, Brown JM, Giaccia A, Loo BW Jr, Shultz DB, Le QT, Koong AC, Chang DT.

Int J Radiat Oncol Biol Phys. 2015 Jul 1;92(3):568-76. doi: 10.1016/j.ijrobp.2015.02.016. Review.

47.

Emerging Treatment Paradigms in Radiation Oncology.

Le QT, Shirato H, Giaccia AJ, Koong AC.

Clin Cancer Res. 2015 Aug 1;21(15):3393-401. doi: 10.1158/1078-0432.CCR-14-1191. Epub 2015 May 19. Review.

48.

Targeting the IRE1α-XBP1 branch of the unfolded protein response in human diseases.

Jiang D, Niwa M, Koong AC.

Semin Cancer Biol. 2015 Aug;33:48-56. doi: 10.1016/j.semcancer.2015.04.010. Epub 2015 May 16. Review.

49.
50.

Comparison of film measurements and Monte Carlo simulations of dose delivered with very high-energy electron beams in a polystyrene phantom.

Bazalova-Carter M, Liu M, Palma B, Dunning M, McCormick D, Hemsing E, Nelson J, Jobe K, Colby E, Koong AC, Tantawi S, Dolgashev V, Maxim PG, Loo BW Jr.

Med Phys. 2015 Apr;42(4):1606-13. doi: 10.1118/1.4914371.

PMID:
25832051

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