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Items: 11


Planar cell polarity gene Fuz triggers apoptosis in neurodegenerative disease models.

Chen ZS, Li L, Peng S, Chen FM, Zhang Q, An Y, Lin X, Li W, Koon AC, Chan TF, Lau KF, Ngo JCK, Wong WT, Kwan KM, Chan HYE.

EMBO Rep. 2018 Jul 19. pii: e45409. doi: 10.15252/embr.201745409. [Epub ahead of print]


Neuronal adaptor FE65 stimulates Rac1-mediated neurite outgrowth by recruiting and activating ELMO1.

Li W, Tam KMV, Chan WWR, Koon AC, Ngo JCK, Chan HYE, Lau KF.

J Biol Chem. 2018 May 18;293(20):7674-7688. doi: 10.1074/jbc.RA117.000505. Epub 2018 Apr 3.


A peptidylic inhibitor for neutralizing expanded CAG RNA-induced nucleolar stress in polyglutamine diseases.

Zhang Q, Chen ZS, An Y, Liu H, Hou Y, Li W, Lau KF, Koon AC, Ngo JCK, Chan HYE.

RNA. 2018 Apr;24(4):486-498. doi: 10.1261/rna.062703.117. Epub 2018 Jan 2.


GULP1/CED-6 ameliorates amyloid-β toxicity in a Drosophila model of Alzheimer's disease.

Vivien Chiu WY, Koon AC, Ki Ngo JC, Edwin Chan HY, Lau KF.

Oncotarget. 2017 Aug 8;8(59):99274-99283. doi: 10.18632/oncotarget.20062. eCollection 2017 Nov 21.


MicroRNAs regulate the sesquiterpenoid hormonal pathway in Drosophila and other arthropods.

Qu Z, Bendena WG, Nong W, Siggens KW, Noriega FG, Kai ZP, Zang YY, Koon AC, Chan HYE, Chan TF, Chu KH, Lam HM, Akam M, Tobe SS, Lam Hui JH.

Proc Biol Sci. 2017 Dec 20;284(1869). pii: 20171827. doi: 10.1098/rspb.2017.1827.


Drosophila melanogaster As a Model Organism to Study RNA Toxicity of Repeat Expansion-Associated Neurodegenerative and Neuromuscular Diseases.

Koon AC, Chan HY.

Front Cell Neurosci. 2017 Mar 21;11:70. doi: 10.3389/fncel.2017.00070. eCollection 2017. Review.


Expanded polyalanine tracts function as nuclear export signals and promote protein mislocalization via eEF1A1 factor.

Li L, Ng NK, Koon AC, Chan HY.

J Biol Chem. 2017 Apr 7;292(14):5784-5800. doi: 10.1074/jbc.M116.763599. Epub 2017 Feb 28.


Inhibitory control of synaptic and behavioral plasticity by octopaminergic signaling.

Koon AC, Budnik V.

J Neurosci. 2012 May 2;32(18):6312-22. doi: 10.1523/JNEUROSCI.6517-11.2012.


Autoregulatory and paracrine control of synaptic and behavioral plasticity by octopaminergic signaling.

Koon AC, Ashley J, Barria R, DasGupta S, Brain R, Waddell S, Alkema MJ, Budnik V.

Nat Neurosci. 2011 Feb;14(2):190-9. doi: 10.1038/nn.2716. Epub 2010 Dec 26.


Activity-dependent regulation of inhibitory synapse development by Npas4.

Lin Y, Bloodgood BL, Hauser JL, Lapan AD, Koon AC, Kim TK, Hu LS, Malik AN, Greenberg ME.

Nature. 2008 Oct 30;455(7217):1198-204. doi: 10.1038/nature07319. Epub 2008 Sep 24.


An RNAi-based approach identifies molecules required for glutamatergic and GABAergic synapse development.

Paradis S, Harrar DB, Lin Y, Koon AC, Hauser JL, Griffith EC, Zhu L, Brass LF, Chen C, Greenberg ME.

Neuron. 2007 Jan 18;53(2):217-32.

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