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Items: 22


TRPM2 ion channels regulate macrophage polarization and gastric inflammation during Helicobacter pylori infection.

Beceiro S, Radin JN, Chatuvedi R, Piazuelo MB, Horvarth DJ, Cortado H, Gu Y, Dixon B, Gu C, Lange I, Koomoa DL, Wilson KT, Algood HM, Partida-Sánchez S.

Mucosal Immunol. 2017 Mar;10(2):493-507. doi: 10.1038/mi.2016.60. Epub 2016 Jul 20.


Scrophularia orientalis extract induces calcium signaling and apoptosis in neuroblastoma cells.

Lange I, Moschny J, Tamanyan K, Khutsishvili M, Atha D, Borris RP, Koomoa DL.

Int J Oncol. 2016 Apr;48(4):1608-16. doi: 10.3892/ijo.2016.3373. Epub 2016 Feb 3.


Differential regulation of calcium signalling pathways by components of Piper methysticum ('Awa).

Shimoda LM, Showman A, Baker JD, Lange I, Koomoa DL, Stokes AJ, Borris RP, Turner H.

Phytother Res. 2015 Apr;29(4):582-90. doi: 10.1002/ptr.5291. Epub 2015 Jan 30.


MycN promotes TRPM7 expression and cell migration in neuroblastoma through a process that involves polyamines.

Lange I, Koomoa DL.

FEBS Open Bio. 2014 Oct 30;4:966-75. doi: 10.1016/j.fob.2014.10.012. eCollection 2014.


DFMO/eflornithine inhibits migration and invasion downstream of MYCN and involves p27Kip1 activity in neuroblastoma.

Koomoa DL, Geerts D, Lange I, Koster J, Pegg AE, Feith DJ, Bachmann AS.

Int J Oncol. 2013 Apr;42(4):1219-28. doi: 10.3892/ijo.2013.1835. Epub 2013 Feb 21.


Subcellular distribution and expression of prenylated Rab acceptor 1 domain family, member 2 (PRAF2) in malignant glioma: Influence on cell survival and migration.

Borsics T, Lundberg E, Geerts D, Koomoa DL, Koster J, Wester K, Bachmann AS.

Cancer Sci. 2010 Jul;101(7):1624-31. doi: 10.1111/j.1349-7006.2010.01570.x. Epub 2010 Mar 19.


Syrbactin class proteasome inhibitor-induced apoptosis and autophagy occurs in association with p53 accumulation and Akt/PKB activation in neuroblastoma.

Archer CR, Koomoa DL, Mitsunaga EM, Clerc J, Shimizu M, Kaiser M, Schellenberg B, Dudler R, Bachmann AS.

Biochem Pharmacol. 2010 Jul 15;80(2):170-8. doi: 10.1016/j.bcp.2010.03.031. Epub 2010 Apr 1.


The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification.

Geerts D, Koster J, Albert D, Koomoa DL, Feith DJ, Pegg AE, Volckmann R, Caron H, Versteeg R, Bachmann AS.

Int J Cancer. 2010 May 1;126(9):2012-24. doi: 10.1002/ijc.25074.


Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma.

Koomoa DL, Borsics T, Feith DJ, Coleman CC, Wallick CJ, Gamper I, Pegg AE, Bachmann AS.

Mol Cancer Ther. 2009 Jul;8(7):2067-75. doi: 10.1158/1535-7163.MCT-08-1217. Epub 2009 Jul 7.


Ornithine decarboxylase inhibition by alpha-difluoromethylornithine activates opposing signaling pathways via phosphorylation of both Akt/protein kinase B and p27Kip1 in neuroblastoma.

Koomoa DL, Yco LP, Borsics T, Wallick CJ, Bachmann AS.

Cancer Res. 2008 Dec 1;68(23):9825-31. doi: 10.1158/0008-5472.CAN-08-1865.


Expression profile of PRAF2 in the human brain and enrichment in synaptic vesicles.

Koomoa DL, Go RC, Wester K, Bachmann AS.

Neurosci Lett. 2008 May 9;436(2):171-6. doi: 10.1016/j.neulet.2008.03.030. Epub 2008 Mar 15.


CRACM1 multimers form the ion-selective pore of the CRAC channel.

Vig M, Beck A, Billingsley JM, Lis A, Parvez S, Peinelt C, Koomoa DL, Soboloff J, Gill DL, Fleig A, Kinet JP, Penner R.

Curr Biol. 2006 Oct 24;16(20):2073-9. Epub 2006 Sep 14.


Amplification of CRAC current by STIM1 and CRACM1 (Orai1).

Peinelt C, Vig M, Koomoa DL, Beck A, Nadler MJ, Koblan-Huberson M, Lis A, Fleig A, Penner R, Kinet JP.

Nat Cell Biol. 2006 Jul;8(7):771-3. Epub 2006 May 30.


CRACM1 is a plasma membrane protein essential for store-operated Ca2+ entry.

Vig M, Peinelt C, Beck A, Koomoa DL, Rabah D, Koblan-Huberson M, Kraft S, Turner H, Fleig A, Penner R, Kinet JP.

Science. 2006 May 26;312(5777):1220-3. Epub 2006 Apr 27.


Osmotic stress stimulates the organic osmolyte channel in Xenopus laevis oocytes expressing skate (Raja erinacea) AE1.

Koomoa DL, Musch MW, Goldstein L.

J Exp Zool A Comp Exp Biol. 2005 Apr 1;303(4):319-22.


Hypotonicity-induced exocytosis of the skate anion exchanger skAE1: role of lipid raft regions.

Musch MW, Koomoa DL, Goldstein L.

J Biol Chem. 2004 Sep 17;279(38):39447-53. Epub 2004 Jul 16.


Expression of the skate (Raja erinacea) AE1 osmolyte channel in Xenopus laevis oocytes: monovalent cation permeability.

Koomoa DL, Musch MW, Myers DE, Goldstein L.

J Membr Biol. 2004 Mar 1;198(1):23-9.


ATP release from hypotonically stressed skate RBC: potential role in osmolyte channel regulation.

Goldstein L, Koomoa DL, Musch MW.

J Exp Zool A Comp Exp Biol. 2003 Apr 1;296(2):160-3.


Comparison of the osmolyte transport properties induced by trAE1 versus IClswell in Xenopus oocytes.

Koomoa DL, Musch MW, Goldstein L.

J Membr Biol. 2002 Jan 1;185(1):57-63. Epub 2002 Feb 5.


Volume-activated trimethylamine oxide efflux in red blood cells of spiny dogfish (Squalus acanthias).

Koomoa DL, Musch MW, MacLean AV, Goldstein L.

Am J Physiol Regul Integr Comp Physiol. 2001 Sep;281(3):R803-10.

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