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Items: 1 to 50 of 164

1.

CARMA3 Mediates Allergic Lung Inflammation in Response to Alternaria alternata.

Causton B, Pardo-Saganta A, Gillis J, Discipio K, Kooistra T, Rajagopal J, Xavier RJ, Cho JL, Medoff BD.

Am J Respir Cell Mol Biol. 2018 Jun 29. doi: 10.1165/rcmb.2017-0181OC. [Epub ahead of print]

PMID:
29958012
2.

CAT-2003: A novel sterol regulatory element-binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3-Leiden mice.

Zimmer M, Bista P, Benson EL, Lee DY, Liu F, Picarella D, Vega RB, Vu CB, Yeager M, Ding M, Liang G, Horton JD, Kleemann R, Kooistra T, Morrison MC, Wielinga PY, Milne JC, Jirousek MR, Nichols AJ.

Hepatol Commun. 2017 May 12;1(4):311-325. doi: 10.1002/hep4.1042. eCollection 2017 Jun.

3.

A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice.

Schoemaker MH, Kleemann R, Morrison MC, Verheij J, Salic K, van Tol EAF, Kooistra T, Wielinga PY.

PLoS One. 2017 Jul 5;12(7):e0180648. doi: 10.1371/journal.pone.0180648. eCollection 2017.

4.

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Morrison MC, Yakala GK, Liang W, Wielinga PY, Salic K, van Koppen A, Tomar T, Kleemann R, Heeringa P, Kooistra T.

Sci Rep. 2017 Jun 6;7(1):2915. doi: 10.1038/s41598-017-02444-2.

5.

Prolonged high-fat diet induces gradual and fat depot-specific DNA methylation changes in adult mice.

Zwamborn RA, Slieker RC, Mulder PC, Zoetemelk I, Verschuren L, Suchiman HE, Toet KH, Droog S, Slagboom PE, Kooistra T, Kleemann R, Heijmans BT.

Sci Rep. 2017 Mar 3;7:43261. doi: 10.1038/srep43261.

6.

Reduction of obesity-associated white adipose tissue inflammation by rosiglitazone is associated with reduced non-alcoholic fatty liver disease in LDLr-deficient mice.

Mulder P, Morrison MC, Verschuren L, Liang W, van Bockel JH, Kooistra T, Wielinga PY, Kleemann R.

Sci Rep. 2016 Aug 22;6:31542. doi: 10.1038/srep31542.

7.

False alarm reduction in critical care.

Clifford GD, Silva I, Moody B, Li Q, Kella D, Chahin A, Kooistra T, Perry D, Mark RG.

Physiol Meas. 2016 Aug;37(8):E5-E23. doi: 10.1088/0967-3334/37/8/E5. Epub 2016 Jul 25.

8.

The PhysioNet/Computing in Cardiology Challenge 2015: Reducing False Arrhythmia Alarms in the ICU.

Clifford GD, Silva I, Moody B, Li Q, Kella D, Shahin A, Kooistra T, Perry D, Mark RG.

Comput Cardiol (2010). 2015 Sep;2015:273-276.

9.

Resolvin E1 attenuates atherosclerosis in absence of cholesterol-lowering effects and on top of atorvastatin.

Salic K, Morrison MC, Verschuren L, Wielinga PY, Wu L, Kleemann R, Gjorstrup P, Kooistra T.

Atherosclerosis. 2016 Jul;250:158-65. doi: 10.1016/j.atherosclerosis.2016.05.001. Epub 2016 May 2.

10.

Defective postreperfusion metabolic recovery directly associates with incident delayed graft function.

Wijermars LG, Schaapherder AF, de Vries DK, Verschuren L, Wüst RC, Kostidis S, Mayboroda OA, Prins F, Ringers J, Bierau J, Bakker JA, Kooistra T, Lindeman JH.

Kidney Int. 2016 Jul;90(1):181-91. doi: 10.1016/j.kint.2016.02.034. Epub 2016 May 14.

PMID:
27188504
11.

Intervention with a caspase-1 inhibitor reduces obesity-associated hyperinsulinemia, non-alcoholic steatohepatitis and hepatic fibrosis in LDLR-/-.Leiden mice.

Morrison MC, Mulder P, Salic K, Verheij J, Liang W, van Duyvenvoorde W, Menke A, Kooistra T, Kleemann R, Wielinga PY.

Int J Obes (Lond). 2016 Sep;40(9):1416-23. doi: 10.1038/ijo.2016.74. Epub 2016 May 28.

12.

Early intake of long-chain polyunsaturated fatty acids preserves brain structure and function in diet-induced obesity.

Arnoldussen IA, Zerbi V, Wiesmann M, Noordman RH, Bolijn S, Mutsaers MP, Dederen PJ, Kleemann R, Kooistra T, van Tol EA, Gross G, Schoemaker MH, Heerschap A, Wielinga PY, Kiliaan AJ.

J Nutr Biochem. 2016 Apr;30:177-88. doi: 10.1016/j.jnutbio.2015.12.011. Epub 2016 Jan 21.

PMID:
27012634
13.

Surgical removal of inflamed epididymal white adipose tissue attenuates the development of non-alcoholic steatohepatitis in obesity.

Mulder P, Morrison MC, Wielinga PY, van Duyvenvoorde W, Kooistra T, Kleemann R.

Int J Obes (Lond). 2016 Apr;40(4):675-84. doi: 10.1038/ijo.2015.226. Epub 2015 Oct 26.

14.

Replacement of Dietary Saturated Fat by PUFA-Rich Pumpkin Seed Oil Attenuates Non-Alcoholic Fatty Liver Disease and Atherosclerosis Development, with Additional Health Effects of Virgin over Refined Oil.

Morrison MC, Mulder P, Stavro PM, Suárez M, Arola-Arnal A, van Duyvenvoorde W, Kooistra T, Wielinga PY, Kleemann R.

PLoS One. 2015 Sep 25;10(9):e0139196. doi: 10.1371/journal.pone.0139196. eCollection 2015.

15.

Quantifying phenotypic flexibility as the response to a high-fat challenge test in different states of metabolic health.

Kardinaal AF, van Erk MJ, Dutman AE, Stroeve JH, van de Steeg E, Bijlsma S, Kooistra T, van Ommen B, Wopereis S.

FASEB J. 2015 Nov;29(11):4600-13. doi: 10.1096/fj.14-269852. Epub 2015 Jul 21.

PMID:
26198450
16.

Mirtoselect, an anthocyanin-rich bilberry extract, attenuates non-alcoholic steatohepatitis and associated fibrosis in ApoE(∗)3Leiden mice.

Morrison MC, Liang W, Mulder P, Verschuren L, Pieterman E, Toet K, Heeringa P, Wielinga PY, Kooistra T, Kleemann R.

J Hepatol. 2015 May;62(5):1180-6. doi: 10.1016/j.jhep.2014.12.011. Epub 2014 Dec 13.

17.

A systems biology approach to understand the pathophysiological mechanisms of cardiac pathological hypertrophy associated with rosiglitazone.

Verschuren L, Wielinga PY, Kelder T, Radonjic M, Salic K, Kleemann R, van Ommen B, Kooistra T.

BMC Med Genomics. 2014 Jun 17;7:35. doi: 10.1186/1755-8794-7-35.

18.

Epicatechin attenuates atherosclerosis and exerts anti-inflammatory effects on diet-induced human-CRP and NFκB in vivo.

Morrison M, van der Heijden R, Heeringa P, Kaijzel E, Verschuren L, Blomhoff R, Kooistra T, Kleemann R.

Atherosclerosis. 2014 Mar;233(1):149-56. doi: 10.1016/j.atherosclerosis.2013.12.027. Epub 2014 Jan 8.

PMID:
24529136
19.

Coordinated and interactive expression of genes of lipid metabolism and inflammation in adipose tissue and liver during metabolic overload.

Liang W, Tonini G, Mulder P, Kelder T, van Erk M, van den Hoek AM, Mariman R, Wielinga PY, Baccini M, Kooistra T, Biggeri A, Kleemann R.

PLoS One. 2013 Sep 25;8(9):e75290. doi: 10.1371/journal.pone.0075290. eCollection 2013.

20.

Effects of chocolate supplementation on metabolic and cardiovascular parameters in ApoE3L mice fed a high-cholesterol atherogenic diet.

Yakala GK, Wielinga PY, Suarez M, Bunschoten A, van Golde JM, Arola L, Keijer J, Kleemann R, Kooistra T, Heeringa P.

Mol Nutr Food Res. 2013 Nov;57(11):2039-48. doi: 10.1002/mnfr.201200858. Epub 2013 Aug 15.

PMID:
23946229
21.

Differential effects of drug interventions and dietary lifestyle in developing type 2 diabetes and complications: a systems biology analysis in LDLr-/- mice.

Radonjic M, Wielinga PY, Wopereis S, Kelder T, Goelela VS, Verschuren L, Toet K, van Duyvenvoorde W, van der Werff van der Vat B, Stroeve JH, Cnubben N, Kooistra T, van Ommen B, Kleemann R.

PLoS One. 2013;8(2):e56122. doi: 10.1371/journal.pone.0056122. Epub 2013 Feb 15.

22.

A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.

van der Meij E, Koning GG, Vriens PW, Peeters MF, Meijer CA, Kortekaas KE, Dalman RL, van Bockel JH, Hanemaaijer R, Kooistra T, Kleemann R, Lindeman JH.

PLoS One. 2013;8(1):e53882. doi: 10.1371/journal.pone.0053882. Epub 2013 Jan 22.

23.

Effects of probiotic Lactobacillus rhamnosus GG and Propionibacterium freudenreichii ssp. shermanii JS supplementation on intestinal and systemic markers of inflammation in ApoE*3Leiden mice consuming a high-fat diet.

Oksaharju A, Kooistra T, Kleemann R, van Duyvenvoorde W, Miettinen M, Lappalainen J, Lindstedt KA, Kovanen PT, Korpela R, Kekkonen RA.

Br J Nutr. 2013 Jul 14;110(1):77-85. doi: 10.1017/S0007114512004801. Epub 2012 Dec 5.

PMID:
23211714
24.

Systems biology analysis unravels the complementary action of combined rosuvastatin and ezetimibe therapy.

Verschuren L, Radonjic M, Wielinga PY, Kelder T, Kooistra T, van Ommen B, Kleemann R.

Pharmacogenet Genomics. 2012 Dec;22(12):837-45. doi: 10.1097/FPC.0b013e328359d274.

PMID:
23086299
25.

Beneficial effects of an alternating high- fat dietary regimen on systemic insulin resistance, hepatic and renal inflammation and renal function.

Yakala GK, van der Heijden R, Molema G, Schipper M, Wielinga PY, Kleemann R, Kooistra T, Heeringa P.

PLoS One. 2012;7(9):e45866. doi: 10.1371/journal.pone.0045866. Epub 2012 Sep 25.

26.

Arachidonic acid/docosahexaenoic acid-supplemented diet in early life reduces body weight gain, plasma lipids, and adiposity in later life in ApoE*3Leiden mice.

Wielinga PY, Harthoorn LF, Verschuren L, Schoemaker MH, Jouni ZE, van Tol EA, Kleemann R, Kooistra T.

Mol Nutr Food Res. 2012 Jul;56(7):1081-9. doi: 10.1002/mnfr.201100762. Epub 2012 May 18.

PMID:
22611002
27.

Psychiatric disorders in Huntington's disease: a 2-year follow-up study.

Reedeker W, van der Mast RC, Giltay EJ, Kooistra TA, Roos RA, van Duijn E.

Psychosomatics. 2012 May-Jun;53(3):220-9. doi: 10.1016/j.psym.2011.12.010. Epub 2012 Mar 27.

PMID:
22458993
28.

Identification of prognostic and diagnostic biomarkers of glucose intolerance in ApoE3Leiden mice.

Wopereis S, Radonjic M, Rubingh C, Erk Mv, Smilde A, Duyvenvoorde Wv, Cnubben N, Kooistra T, Ommen Bv, Kleemann R.

Physiol Genomics. 2012 Mar 1;44(5):293-304. doi: 10.1152/physiolgenomics.00072.2011. Epub 2012 Jan 10.

PMID:
22234995
29.

Metabolic stress-induced inflammation plays a major role in the development of osteoarthritis in mice.

Gierman LM, van der Ham F, Koudijs A, Wielinga PY, Kleemann R, Kooistra T, Stoop R, Kloppenburg M, van Osch GJ, Stojanovic-Susulic V, Huizinga TW, Zuurmond AM.

Arthritis Rheum. 2012 Apr;64(4):1172-81. doi: 10.1002/art.33443. Epub 2011 Oct 27.

30.

Pathogenesis of postoperative adhesion formation.

Hellebrekers BW, Kooistra T.

Br J Surg. 2011 Nov;98(11):1503-16. doi: 10.1002/bjs.7657. Epub 2011 Aug 23. Review.

PMID:
21877324
31.

Exploring pathway interactions in insulin resistant mouse liver.

Kelder T, Eijssen L, Kleemann R, van Erk M, Kooistra T, Evelo C.

BMC Syst Biol. 2011 Aug 15;5:127. doi: 10.1186/1752-0509-5-127.

32.

A systems biology strategy for predicting similarities and differences of drug effects: evidence for drug-specific modulation of inflammation in atherosclerosis.

Kleemann R, Bureeva S, Perlina A, Kaput J, Verschuren L, Wielinga PY, Hurt-Camejo E, Nikolsky Y, van Ommen B, Kooistra T.

BMC Syst Biol. 2011 Aug 12;5:125. doi: 10.1186/1752-0509-5-125.

33.

Anti-inflammatory, anti-proliferative and anti-atherosclerotic effects of quercetin in human in vitro and in vivo models.

Kleemann R, Verschuren L, Morrison M, Zadelaar S, van Erk MJ, Wielinga PY, Kooistra T.

Atherosclerosis. 2011 Sep;218(1):44-52. doi: 10.1016/j.atherosclerosis.2011.04.023. Epub 2011 May 5.

PMID:
21601209
34.

Beneficial effects of alternate dietary regimen on liver inflammation, atherosclerosis and renal activation.

Wielinga PY, Yakala GK, Heeringa P, Kleemann R, Kooistra T.

PLoS One. 2011 Mar 31;6(3):e18432. doi: 10.1371/journal.pone.0018432.

35.

Semi-automated non-target processing in GC × GC-MS metabolomics analysis: applicability for biomedical studies.

Koek MM, van der Kloet FM, Kleemann R, Kooistra T, Verheij ER, Hankemeier T.

Metabolomics. 2011 Mar;7(1):1-14. Epub 2010 Jul 15.

36.

A dietary mixture containing fish oil, resveratrol, lycopene, catechins, and vitamins E and C reduces atherosclerosis in transgenic mice.

Verschuren L, Wielinga PY, van Duyvenvoorde W, Tijani S, Toet K, van Ommen B, Kooistra T, Kleemann R.

J Nutr. 2011 May;141(5):863-9. doi: 10.3945/jn.110.133751. Epub 2011 Mar 16.

37.

Histone H3K27ac separates active from poised enhancers and predicts developmental state.

Creyghton MP, Cheng AW, Welstead GG, Kooistra T, Carey BW, Steine EJ, Hanna J, Lodato MA, Frampton GM, Sharp PA, Boyer LA, Young RA, Jaenisch R.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21931-6. doi: 10.1073/pnas.1016071107. Epub 2010 Nov 24.

38.

Chronic TNF-α neutralization does not improve insulin resistance or endothelial function in "healthy" men with metabolic syndrome.

Wascher TC, Lindeman JH, Sourij H, Kooistra T, Pacini G, Roden M.

Mol Med. 2011 Mar-Apr;17(3-4):189-93. doi: 10.2119/molmed.2010.00221. Epub 2010 Nov 16.

39.

Anti-inflammatory salicylate beneficially modulates pre-existing atherosclerosis through quenching of NF-κB activity and lowering of cholesterol.

de Vries-van der Weij J, Toet K, Zadelaar S, Wielinga PY, Kleemann R, Rensen PC, Kooistra T.

Atherosclerosis. 2010 Nov;213(1):241-6. doi: 10.1016/j.atherosclerosis.2010.09.006. Epub 2010 Sep 21.

PMID:
20926077
40.

A combined transcriptomics and lipidomics analysis of subcutaneous, epididymal and mesenteric adipose tissue reveals marked functional differences.

Caesar R, Manieri M, Kelder T, Boekschoten M, Evelo C, Müller M, Kooistra T, Cinti S, Kleemann R, Drevon CA.

PLoS One. 2010 Jul 12;5(7):e11525. doi: 10.1371/journal.pone.0011525.

41.

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans.

Shivers RP, Pagano DJ, Kooistra T, Richardson CE, Reddy KC, Whitney JK, Kamanzi O, Matsumoto K, Hisamoto N, Kim DH.

PLoS Genet. 2010 Apr 1;6(4):e1000892. doi: 10.1371/journal.pgen.1000892.

42.

An essential role for XBP-1 in host protection against immune activation in C. elegans.

Richardson CE, Kooistra T, Kim DH.

Nature. 2010 Feb 25;463(7284):1092-5. doi: 10.1038/nature08762.

43.

An antiinflammatory dietary mix modulates inflammation and oxidative and metabolic stress in overweight men: a nutrigenomics approach.

Bakker GC, van Erk MJ, Pellis L, Wopereis S, Rubingh CM, Cnubben NH, Kooistra T, van Ommen B, Hendriks HF.

Am J Clin Nutr. 2010 Apr;91(4):1044-59. doi: 10.3945/ajcn.2009.28822. Epub 2010 Feb 24.

PMID:
20181810
44.

Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance.

Kleemann R, van Erk M, Verschuren L, van den Hoek AM, Koek M, Wielinga PY, Jie A, Pellis L, Bobeldijk-Pastorova I, Kelder T, Toet K, Wopereis S, Cnubben N, Evelo C, van Ommen B, Kooistra T.

PLoS One. 2010 Jan 21;5(1):e8817. doi: 10.1371/journal.pone.0008817.

45.

Ritonavir protects against the development of atherosclerosis in APOE*3-Leiden mice.

den Boer MA, Westerterp M, de Vries-van der Weij J, Wang Y, Hu L, Espirito Santo SM, Kooistra T, Reiss P, Romijn JA, Havekes LM, Rensen PC.

Atherosclerosis. 2010 Jun;210(2):381-7. doi: 10.1016/j.atherosclerosis.2009.11.043. Epub 2009 Dec 1.

PMID:
20060117
46.

Tissue-specific activities of an immune signaling module regulate physiological responses to pathogenic and nutritional bacteria in C. elegans.

Shivers RP, Kooistra T, Chu SW, Pagano DJ, Kim DH.

Cell Host Microbe. 2009 Oct 22;6(4):321-30. doi: 10.1016/j.chom.2009.09.001.

47.

Diet-induced obesity increases NF-kappaB signaling in reporter mice.

Carlsen H, Haugen F, Zadelaar S, Kleemann R, Kooistra T, Drevon CA, Blomhoff R.

Genes Nutr. 2009 Sep;4(3):215-22. doi: 10.1007/s12263-009-0133-6. Epub 2009 Aug 26.

48.

MIF deficiency reduces chronic inflammation in white adipose tissue and impairs the development of insulin resistance, glucose intolerance, and associated atherosclerotic disease.

Verschuren L, Kooistra T, Bernhagen J, Voshol PJ, Ouwens DM, van Erk M, de Vries-van der Weij J, Leng L, van Bockel JH, van Dijk KW, Fingerle-Rowson G, Bucala R, Kleemann R.

Circ Res. 2009 Jul 2;105(1):99-107. doi: 10.1161/CIRCRESAHA.109.199166. Epub 2009 May 28.

49.

Human CETP aggravates atherosclerosis by increasing VLDL-cholesterol rather than by decreasing HDL-cholesterol in APOE*3-Leiden mice.

de Vries-van der Weij J, Zadelaar S, Toet K, Havekes LM, Kooistra T, Rensen PC.

Atherosclerosis. 2009 Sep;206(1):153-8. doi: 10.1016/j.atherosclerosis.2009.02.038. Epub 2009 Mar 19.

PMID:
19345354
50.

Improving the analysis of designed studies by combining statistical modelling with study design information.

Thissen U, Wopereis S, van den Berg SA, Bobeldijk I, Kleemann R, Kooistra T, van Dijk KW, van Ommen B, Smilde AK.

BMC Bioinformatics. 2009 Feb 7;10:52. doi: 10.1186/1471-2105-10-52.

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