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Items: 1 to 50 of 727

1.

Cocaine-induced ischemia in prefrontal cortex is associated with escalation of cocaine intake in rodents.

Du C, Volkow ND, You J, Park K, Allen CP, Koob GF, Pan Y.

Mol Psychiatry. 2018 Oct 3. doi: 10.1038/s41380-018-0261-8. [Epub ahead of print]

PMID:
30283033
2.

Addiction and stress: An allostatic view.

Koob GF, Schulkin J.

Neurosci Biobehav Rev. 2018 Sep 15. pii: S0149-7634(18)30218-5. doi: 10.1016/j.neubiorev.2018.09.008. [Epub ahead of print] Review.

PMID:
30227143
3.

Ethanol Reinforcement Elicits Novel Response Inhibition Behavior in a Rat Model of Ethanol Dependence.

Somkuwar SS, Quach LW, Quigley JA, Purohit DC, Fannon MJ, Koob GF, Mandyam CD.

Brain Sci. 2018 Jun 26;8(7). pii: E119. doi: 10.3390/brainsci8070119.

4.

Subthalamic nucleus high frequency stimulation prevents and reverses escalated cocaine use.

Pelloux Y, Degoulet M, Tiran-Cappello A, Cohen C, Lardeux S, George O, Koob GF, Ahmed SH, Baunez C.

Mol Psychiatry. 2018 Jun 7. doi: 10.1038/s41380-018-0080-y. [Epub ahead of print]

PMID:
29880881
5.

Promoting Wellness in Older Adults with Mental Illnesses and Substance Use Disorders: Call to Action to All Stakeholders.

Jeste DV, Peschin S, Buckwalter K, Blazer DG, McGuire MH, Moutier C, Doederlein A, Niederehe G, Altman B, Borenstein J, Saks E, Norquist G, Koob GF, Compton WM, Sperling A, Bain L, Glorioso D, Paul IH, Reynolds CF 3rd.

Am J Geriatr Psychiatry. 2018 Jun;26(6):617-630. doi: 10.1016/j.jagp.2018.03.011. Epub 2018 Apr 26. No abstract available.

6.

Influence of alcoholism and cholesterol on TSPO binding in brain: PET [11C]PBR28 studies in humans and rodents.

Kim SW, Wiers CE, Tyler R, Shokri-Kojori E, Jang YJ, Zehra A, Freeman C, Ramirez V, Lindgren E, Miller G, Cabrera EA, Stodden T, Guo M, Demiral ŞB, Diazgranados N, Park L, Liow JS, Pike V, Morse C, Vendruscolo LF, Innis RB, Koob GF, Tomasi D, Wang GJ, Volkow ND.

Neuropsychopharmacology. 2018 Aug;43(9):1832-1839. doi: 10.1038/s41386-018-0085-x. Epub 2018 May 3.

7.

Knockdown of hypocretin attenuates extended access of cocaine self-administration in rats.

Schmeichel BE, Matzeu A, Koebel P, Vendruscolo LF, Sidhu H, Shahryari R, Kieffer BL, Koob GF, Martin-Fardon R, Contet C.

Neuropsychopharmacology. 2018 Nov;43(12):2373-2382. doi: 10.1038/s41386-018-0054-4. Epub 2018 Apr 6.

PMID:
29703996
8.

Animal Models of Addiction and Neuropsychiatric Disorders and Their Role in Drug Discovery: Honoring the Legacy of Athina Markou.

Kenny PJ, Hoyer D, Koob GF.

Biol Psychiatry. 2018 Jun 1;83(11):940-946. doi: 10.1016/j.biopsych.2018.02.009. Epub 2018 Feb 22. Review.

PMID:
29602521
9.

Age, Alcohol Use, and Brain Function: Yoda Says, "With Age and Alcohol, Confused Is the Force".

Koob GF.

JAMA Psychiatry. 2018 May 1;75(5):422. doi: 10.1001/jamapsychiatry.2018.0009. No abstract available.

PMID:
29541767
10.

Enhanced neuronal and blunted hemodynamic reactivity to cocaine in the prefrontal cortex following extended cocaine access: optical imaging study in anesthetized rats.

Allen CP, Park K, Li A, Volkow ND, Koob GF, Pan Y, Hu XT, Du C.

Addict Biol. 2018 Mar 5. doi: 10.1111/adb.12615. [Epub ahead of print]

PMID:
29504647
11.

Evaluation of Alcohol Preference and Drinking in msP Rats Bearing a Crhr1 Promoter Polymorphism.

Logrip ML, Walker JR, Ayanwuyi LO, Sabino V, Ciccocioppo R, Koob GF, Zorrilla EP.

Front Psychiatry. 2018 Feb 15;9:28. doi: 10.3389/fpsyt.2018.00028. eCollection 2018.

12.

Development and initial characterization of a novel ghrelin receptor CRISPR/Cas9 knockout wistar rat model.

Zallar LJ, Tunstall BJ, Richie CT, Zhang YJ, You ZB, Gardner EL, Heilig M, Pickel J, Koob GF, Vendruscolo LF, Harvey BK, Leggio L.

Int J Obes (Lond). 2018 Jan 30. doi: 10.1038/s41366-018-0013-5. [Epub ahead of print]

13.

Median and Dorsal Raphe Serotonergic Neurons Control Moderate Versus Compulsive Cocaine Intake.

Verheij MMM, Contet C, Karel P, Latour J, van der Doelen RHA, Geenen B, van Hulten JA, Meyer F, Kozicz T, George O, Koob GF, Homberg JR.

Biol Psychiatry. 2018 Jun 15;83(12):1024-1035. doi: 10.1016/j.biopsych.2017.10.031. Epub 2017 Nov 20.

PMID:
29357981
14.

Blockade of TRPV1 Inhibits Methamphetamine-induced Rewarding Effects.

Tian YH, Ma SX, Lee KW, Wee S, Koob GF, Lee SY, Jang CG.

Sci Rep. 2018 Jan 17;8(1):882. doi: 10.1038/s41598-018-19207-2.

15.

Individual differences in the neuropsychopathology of addiction.

George O, Koob GF.

Dialogues Clin Neurosci. 2017 Sep;19(3):217-229. Review.

16.

Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats.

Tunstall BJ, Ho CP, Cao J, Vendruscolo JCM, Schmeichel BE, Slack RD, Tanda G, Gadiano AJ, Rais R, Slusher BS, Koob GF, Newman AH, Vendruscolo LF.

Neuropharmacology. 2018 Mar 15;131:96-103. doi: 10.1016/j.neuropharm.2017.12.006. Epub 2017 Dec 5.

PMID:
29217282
17.

The conception of the ABCD study: From substance use to a broad NIH collaboration.

Volkow ND, Koob GF, Croyle RT, Bianchi DW, Gordon JA, Koroshetz WJ, Pérez-Stable EJ, Riley WT, Bloch MH, Conway K, Deeds BG, Dowling GJ, Grant S, Howlett KD, Matochik JA, Morgan GD, Murray MM, Noronha A, Spong CY, Wargo EM, Warren KR, Weiss SRB.

Dev Cogn Neurosci. 2018 Aug;32:4-7. doi: 10.1016/j.dcn.2017.10.002. Epub 2017 Oct 10. Review.

18.

Opiate dependence induces cell type-specific plasticity of intrinsic membrane properties in the rat juxtacapsular bed nucleus of stria terminalis (jcBNST).

Francesconi W, Szücs A, Berton F, Koob GF, Vendruscolo LF, Sanna PP.

Psychopharmacology (Berl). 2017 Dec;234(23-24):3485-3498. doi: 10.1007/s00213-017-4732-4. Epub 2017 Oct 6.

19.

Neuroscience of Compulsive Eating Behavior.

Moore CF, Sabino V, Koob GF, Cottone P.

Front Neurosci. 2017 Aug 24;11:469. doi: 10.3389/fnins.2017.00469. eCollection 2017. Review.

20.

Methylomic profiling and replication implicates deregulation of PCSK9 in alcohol use disorder.

Lohoff FW, Sorcher JL, Rosen AD, Mauro KL, Fanelli RR, Momenan R, Hodgkinson CA, Vendruscolo LF, Koob GF, Schwandt M, George DT, Jones IS, Holmes A, Zhou Z, Xu MJ, Gao B, Sun H, Phillips MJ, Muench C, Kaminsky ZA.

Mol Psychiatry. 2017 Aug 29. doi: 10.1038/mp.2017.168. [Epub ahead of print]

21.

Compulsive-Like Sufentanil Vapor Self-Administration in Rats.

Vendruscolo JCM, Tunstall BJ, Carmack SA, Schmeichel BE, Lowery-Gionta EG, Cole M, George O, Vandewater SA, Taffe MA, Koob GF, Vendruscolo LF.

Neuropsychopharmacology. 2018 Mar;43(4):801-809. doi: 10.1038/npp.2017.172. Epub 2017 Aug 16.

PMID:
28812595
22.

Neuroclinical Framework for the Role of Stress in Addiction.

Kwako LE, Koob GF.

Chronic Stress (Thousand Oaks). 2017 Feb;1. doi: 10.1177/2470547017698140. Epub 2017 Apr 10.

23.

The future is now: A 2020 view of alcoholism research.

Harris RA, Koob GF.

Neuropharmacology. 2017 Aug 1;122:1-2. doi: 10.1016/j.neuropharm.2017.06.001. No abstract available.

24.

Dysregulation of Brain Stress Systems Mediates Compulsive Alcohol Drinking.

Tunstall BJ, Carmack SA, Koob GF, Vendruscolo LF.

Curr Opin Behav Sci. 2017 Feb;13:85-90. doi: 10.1016/j.cobeha.2016.10.006. Epub 2016 Nov 19.

25.

A relationship between the aldosterone-mineralocorticoid receptor pathway and alcohol drinking: preliminary translational findings across rats, monkeys and humans.

Aoun EG, Jimenez VA, Vendruscolo LF, Walter NAR, Barbier E, Ferrulli A, Haass-Koffler CL, Darakjian P, Lee MR, Addolorato G, Heilig M, Hitzemann R, Koob GF, Grant KA, Leggio L.

Mol Psychiatry. 2018 Jun;23(6):1466-1473. doi: 10.1038/mp.2017.97. Epub 2017 May 2.

26.

A new nomenclature for classifying psychotropic drugs.

Caraci F, Enna SJ, Zohar J, Racagni G, Zalsman G, van den Brink W, Kasper S, Koob GF, Pariante CM, Piazza PV, Yamada K, Spedding M, Drago F.

Br J Clin Pharmacol. 2017 Aug;83(8):1614-1616. doi: 10.1111/bcp.13302. Epub 2017 May 24.

27.

Titrating Tipsy Targets: The Neurobiology of Low-Dose Alcohol.

Cui C, Koob GF.

Trends Pharmacol Sci. 2017 Jun;38(6):556-568. doi: 10.1016/j.tips.2017.03.002. Epub 2017 Mar 31. Review.

28.

A synthetic small-molecule Isoxazole-9 protects against methamphetamine relapse.

Galinato MH, Lockner JW, Fannon-Pavlich MJ, Sobieraj JC, Staples MC, Somkuwar SS, Ghofranian A, Chaing S, Navarro AI, Joea A, Luikart BW, Janda KD, Heyser C, Koob GF, Mandyam CD.

Mol Psychiatry. 2018 Mar;23(3):629-638. doi: 10.1038/mp.2017.46. Epub 2017 Mar 28.

29.

Addictions Neuroclinical Assessment: A reverse translational approach.

Kwako LE, Momenan R, Grodin EN, Litten RZ, Koob GF, Goldman D.

Neuropharmacology. 2017 Aug 1;122:254-264. doi: 10.1016/j.neuropharm.2017.03.006. Epub 2017 Mar 7. Review.

30.

Genetic studies of alcohol dependence in the context of the addiction cycle.

Reilly MT, Noronha A, Goldman D, Koob GF.

Neuropharmacology. 2017 Aug 1;122:3-21. doi: 10.1016/j.neuropharm.2017.01.017. Epub 2017 Jan 22. Review.

31.

Antireward, compulsivity, and addiction: seminal contributions of Dr. Athina Markou to motivational dysregulation in addiction.

Koob GF.

Psychopharmacology (Berl). 2017 May;234(9-10):1315-1332. doi: 10.1007/s00213-016-4484-6. Epub 2017 Jan 3. Review.

PMID:
28050629
32.

Genetic and Pharmacologic Manipulation of TLR4 Has Minimal Impact on Ethanol Consumption in Rodents.

Harris RA, Bajo M, Bell RL, Blednov YA, Varodayan FP, Truitt JM, de Guglielmo G, Lasek AW, Logrip ML, Vendruscolo LF, Roberts AJ, Roberts E, George O, Mayfield J, Billiar TR, Hackam DJ, Mayfield RD, Koob GF, Roberto M, Homanics GE.

J Neurosci. 2017 Feb 1;37(5):1139-1155. doi: 10.1523/JNEUROSCI.2002-16.2016. Epub 2016 Dec 16.

33.

Pathological Overeating: Emerging Evidence for a Compulsivity Construct.

Moore CF, Sabino V, Koob GF, Cottone P.

Neuropsychopharmacology. 2017 Jun;42(7):1375-1389. doi: 10.1038/npp.2016.269. Epub 2016 Dec 6. Review.

34.

High-Frequency Stimulation of the Subthalamic Nucleus Blocks Compulsive-Like Re-Escalation of Heroin Taking in Rats.

Wade CL, Kallupi M, Hernandez DO, Breysse E, de Guglielmo G, Crawford E, Koob GF, Schweitzer P, Baunez C, George O.

Neuropsychopharmacology. 2017 Aug;42(9):1850-1859. doi: 10.1038/npp.2016.270. Epub 2016 Dec 5.

35.

Reply to: Neuroclinical Assessment of Addiction Needs to Incorporate Decision-Making Measures and Ecological Validity.

Kwako LE, Momenan R, Litten RZ, Koob GF, Goldman D.

Biol Psychiatry. 2017 Apr 1;81(7):e55. doi: 10.1016/j.biopsych.2016.08.029. Epub 2016 Aug 30. No abstract available.

PMID:
27776735
36.

A Phase 2, Double-Blind, Placebo-Controlled Randomized Trial Assessing the Efficacy of ABT-436, a Novel V1b Receptor Antagonist, for Alcohol Dependence.

Ryan ML, Falk DE, Fertig JB, Rendenbach-Mueller B, Katz DA, Tracy KA, Strain EC, Dunn KE, Kampman K, Mahoney E, Ciraulo DA, Sickles-Colaneri L, Ait-Daoud N, Johnson BA, Ransom J, Scott C, Koob GF, Litten RZ.

Neuropsychopharmacology. 2017 Apr;42(5):1012-1023. doi: 10.1038/npp.2016.214. Epub 2016 Sep 23.

37.

Recruitment of a Neuronal Ensemble in the Central Nucleus of the Amygdala Is Required for Alcohol Dependence.

de Guglielmo G, Crawford E, Kim S, Vendruscolo LF, Hope BT, Brennan M, Cole M, Koob GF, George O.

J Neurosci. 2016 Sep 7;36(36):9446-53. doi: 10.1523/JNEUROSCI.1395-16.2016.

38.

Hypocretin Neurotransmission Within the Central Amygdala Mediates Escalated Cocaine Self-administration and Stress-Induced Reinstatement in Rats.

Schmeichel BE, Herman MA, Roberto M, Koob GF.

Biol Psychiatry. 2017 Apr 1;81(7):606-615. doi: 10.1016/j.biopsych.2016.06.010. Epub 2016 Jun 16.

39.

Corticotropin-Releasing Factor From Rodents to Primates: Translational Hope Expresses Itself, Pun Intended.

Koob GF.

Biol Psychiatry. 2016 Sep 1;80(5):340-2. doi: 10.1016/j.biopsych.2016.06.015. No abstract available.

40.

Sex, strain, and estrous cycle influences on alcohol drinking in rats.

Priddy BM, Carmack SA, Thomas LC, Vendruscolo JC, Koob GF, Vendruscolo LF.

Pharmacol Biochem Behav. 2017 Jan;152:61-67. doi: 10.1016/j.pbb.2016.08.001. Epub 2016 Aug 4.

41.

Systemic Delivery of a Brain-Penetrant TrkB Antagonist Reduces Cocaine Self-Administration and Normalizes TrkB Signaling in the Nucleus Accumbens and Prefrontal Cortex.

Verheij MM, Vendruscolo LF, Caffino L, Giannotti G, Cazorla M, Fumagalli F, Riva MA, Homberg JR, Koob GF, Contet C.

J Neurosci. 2016 Aug 3;36(31):8149-59. doi: 10.1523/JNEUROSCI.2711-14.2016.

42.

Neurobiology of addiction: a neurocircuitry analysis.

Koob GF, Volkow ND.

Lancet Psychiatry. 2016 Aug;3(8):760-73. doi: 10.1016/S2215-0366(16)00104-8. Review.

43.

The Dark Side of Addiction: The Horsley Gantt to Joseph Brady Connection.

Koob GF.

J Nerv Ment Dis. 2017 Apr;205(4):270-272. doi: 10.1097/NMD.0000000000000551.

44.

Basic science: Bedrock of progress.

Collins FS, Anderson JM, Austin CP, Battey JF, Birnbaum LS, Briggs JP, Clayton JA, Cuthbert B, Eisinger RW, Fauci AS, Gallin JI, Gibbons GH, Glass RI, Gottesman MM, Gray PA, Green ED, Greider FB, Hodes R, Hudson KL, Humphreys B, Katz SI, Koob GF, Koroshetz WJ, Lauer MS, Lorsch JR, Lowy DR, McGowan JJ, Murray DM, Nakamura R, Norris A, Perez-Stable EJ, Pettigrew RI, Riley WT, Rodgers GP, Sieving PA, Somerman MJ, Spong CY, Tabak LA, Volkow ND, Wilder EL.

Science. 2016 Mar 25;351(6280):1405. doi: 10.1126/science.351.6280.1405-a. No abstract available.

45.

11β-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse.

Sanna PP, Kawamura T, Chen J, Koob GF, Roberts AJ, Vendruscolo LF, Repunte-Canonigo V.

Transl Psychiatry. 2016 Mar 15;6:e760. doi: 10.1038/tp.2016.13.

46.

Neurobiologic Advances from the Brain Disease Model of Addiction.

Volkow ND, Koob GF, McLellan AT.

N Engl J Med. 2016 Jan 28;374(4):363-71. doi: 10.1056/NEJMra1511480. Review. No abstract available.

47.

Sex Differences in Animal Models: Focus on Addiction.

Becker JB, Koob GF.

Pharmacol Rev. 2016 Apr;68(2):242-63. doi: 10.1124/pr.115.011163. Review.

48.

Addictions Neuroclinical Assessment: A Neuroscience-Based Framework for Addictive Disorders.

Kwako LE, Momenan R, Litten RZ, Koob GF, Goldman D.

Biol Psychiatry. 2016 Aug 1;80(3):179-89. doi: 10.1016/j.biopsych.2015.10.024. Epub 2015 Nov 17. Review.

49.

Dynorphin, Dysphoria, and Dependence: the Stress of Addiction.

Chavkin C, Koob GF.

Neuropsychopharmacology. 2016 Jan;41(1):373-4. doi: 10.1038/npp.2015.258. Review. No abstract available.

50.

Existing and Future Drugs for the Treatment of the Dark Side of Addiction.

Koob GF, Mason BJ.

Annu Rev Pharmacol Toxicol. 2016;56:299-322. doi: 10.1146/annurev-pharmtox-010715-103143. Epub 2015 Oct 22. Review.

PMID:
26514207

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