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Items: 1 to 50 of 173

1.

Evidence that NLRC4 inflammasome mediates apoptotic and pyroptotic microglial death following ischemic stroke.

Poh L, Kang SW, Baik SH, Ng GYQ, She DT, Balaganapathy P, Dheen ST, Magnus T, Gelderblom M, Sobey CG, Koo EH, Fann DY, Arumugam TV.

Brain Behav Immun. 2018 Sep 5. pii: S0889-1591(18)30544-0. doi: 10.1016/j.bbi.2018.09.001. [Epub ahead of print]

PMID:
30195027
2.

Tauopathy-associated PERK alleles are functional hypomorphs that increase neuronal vulnerability to ER stress.

Yuan SH, Hiramatsu N, Liu Q, Sun XV, Lenh D, Chan P, Chiang K, Koo EH, Kao AW, Litvan I, Lin JH.

Hum Mol Genet. 2018 Nov 15;27(22):3951-3963. doi: 10.1093/hmg/ddy297.

PMID:
30137327
3.

Outcomes of conventional phacoemulsification versus femtosecond laser-assisted cataract surgery in eyes with Fuchs endothelial corneal dystrophy.

Zhu DC, Shah P, Feuer WJ, Shi W, Koo EH.

J Cataract Refract Surg. 2018 May;44(5):534-540. doi: 10.1016/j.jcrs.2018.03.023.

PMID:
29773458
4.

APP upregulation contributes to retinal ganglion cell degeneration via JNK3.

Liu C, Zhang CW, Zhou Y, Wong WQ, Lee LC, Ong WY, Yoon SO, Hong W, Fu XY, Soong TW, Koo EH, Stanton LW, Lim KL, Xiao ZC, Dawe GS.

Cell Death Differ. 2018 Mar;25(4):661-676. doi: 10.1038/s41418-017-0005-3. Epub 2017 Dec 13.

5.

Short Aβ peptides attenuate Aβ42 toxicity in vivo.

Moore BD, Martin J, de Mena L, Sanchez J, Cruz PE, Ceballos-Diaz C, Ladd TB, Ran Y, Levites Y, Kukar TL, Kurian JJ, McKenna R, Koo EH, Borchelt DR, Janus C, Rincon-Limas D, Fernandez-Funez P, Golde TE.

J Exp Med. 2018 Jan 2;215(1):283-301. doi: 10.1084/jem.20170600. Epub 2017 Dec 5.

6.

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR 3rd.

Cell Rep. 2017 Nov 28;21(9):2614-2627. doi: 10.1016/j.celrep.2017.11.009.

7.

Effects of temperature and fluid media on the scroll width size of the Descemet's membrane endothelial keratoplasty (DMEK) donor graft.

Koo EH, Eghrari AO, Meshkin RS, Shi W, Feuer WJ, DeMarco KG, Kurz AC.

Clin Ophthalmol. 2017 Sep 1;11:1611-1615. doi: 10.2147/OPTH.S143427. eCollection 2017.

8.

Dimerization leads to changes in APP (amyloid precursor protein) trafficking mediated by LRP1 and SorLA.

Eggert S, Gonzalez AC, Thomas C, Schilling S, Schwarz SM, Tischer C, Adam V, Strecker P, Schmidt V, Willnow TE, Hermey G, Pietrzik CU, Koo EH, Kins S.

Cell Mol Life Sci. 2018 Jan;75(2):301-322. doi: 10.1007/s00018-017-2625-7. Epub 2017 Aug 10.

PMID:
28799085
9.
10.

APLP1 Is a Synaptic Cell Adhesion Molecule, Supporting Maintenance of Dendritic Spines and Basal Synaptic Transmission.

Schilling S, Mehr A, Ludewig S, Stephan J, Zimmermann M, August A, Strecker P, Korte M, Koo EH, Müller UC, Kins S, Eggert S.

J Neurosci. 2017 May 24;37(21):5345-5365. doi: 10.1523/JNEUROSCI.1875-16.2017. Epub 2017 Apr 27.

11.

Cataracts induced by neodymium-yttrium-aluminium-garnet laser lysis of vitreous floaters.

Koo EH, Haddock LJ, Bhardwaj N, Fortun JA.

Br J Ophthalmol. 2017 Jun;101(6):709-711. doi: 10.1136/bjophthalmol-2016-309005. Epub 2016 Aug 29.

PMID:
27574177
12.

The Utility of Brief Cognitive Tests for Patients With Type 2 Diabetes Mellitus: A Systematic Review.

Dong Y, Kua ZJ, Khoo EY, Koo EH, Merchant RA.

J Am Med Dir Assoc. 2016 Oct 1;17(10):889-95. doi: 10.1016/j.jamda.2016.06.010. Epub 2016 Jul 25. Review.

PMID:
27461866
13.

Deficiency in either COX-1 or COX-2 genes does not affect amyloid beta protein burden in amyloid precursor protein transgenic mice.

Park SA, Chevallier N, Tejwani K, Hung MM, Maruyama H, Golde TE, Koo EH.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):286-292. doi: 10.1016/j.bbrc.2016.07.015. Epub 2016 Jul 15.

PMID:
27425247
14.

Diagnostic performances of M-protein tests according to the clinical presentations of kidney disease.

Koo EH, Shin JH, Jang HR, Park HD, Kwon GY, Huh W, Kim DJ, Kim YG, Oh HY, Lee JE.

Eur J Intern Med. 2016 Sep;33:88-92. doi: 10.1016/j.ejim.2016.06.028. Epub 2016 Jul 12.

PMID:
27421913
15.

Renal artery stenosis presenting with nephrotic-range proteinuria: a case report.

Hwang S, Ham JS, Hwang KB, Jeong SH, Ha SH, Koo EH, Kwon GY, Do YS, Jang HR.

Kidney Res Clin Pract. 2016 Jun;35(2):119-22. doi: 10.1016/j.krcp.2015.08.006. Epub 2015 Sep 2.

16.

γ-Secretase Modulators and APH1 Isoforms Modulate γ-Secretase Cleavage but Not Position of ε-Cleavage of the Amyloid Precursor Protein (APP).

Lessard CB, Cottrell BA, Maruyama H, Suresh S, Golde TE, Koo EH.

PLoS One. 2015 Dec 17;10(12):e0144758. doi: 10.1371/journal.pone.0144758. eCollection 2015.

17.

Inter-Dependent Mechanisms Behind Cognitive Dysfunction, Vascular Biology and Alzheimer's Dementia in Down Syndrome: Multi-Faceted Roles of APP.

Nizetic D, Chen CL, Hong W, Koo EH.

Front Behav Neurosci. 2015 Dec 1;9:299. doi: 10.3389/fnbeh.2015.00299. eCollection 2015.

18.

Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway.

Das U, Wang L, Ganguly A, Saikia JM, Wagner SL, Koo EH, Roy S.

Nat Neurosci. 2016 Jan;19(1):55-64. doi: 10.1038/nn.4188. Epub 2015 Dec 7.

19.

The impact of slow graft function on graft outcome is comparable to delayed graft function in deceased donor kidney transplantation.

Shin JH, Koo EH, Ha SH, Park JH, Jang HR, Lee JE, Park JB, Kim SJ, Jung SH, Kim YG, Kim DJ, Oh HY, Huh W.

Int Urol Nephrol. 2016 Mar;48(3):431-9. doi: 10.1007/s11255-015-1163-1. Epub 2015 Nov 18.

PMID:
26581566
20.

New tricks from an old dog: Another synaptotoxic fragment from APP.

Tyan SH, Koo EH.

Cell Res. 2015 Nov;25(11):1185-6. doi: 10.1038/cr.2015.125. Epub 2015 Oct 27.

21.

The impact of early and late acute rejection on graft survival in renal transplantation.

Koo EH, Jang HR, Lee JE, Park JB, Kim SJ, Kim DJ, Kim YG, Oh HY, Huh W.

Kidney Res Clin Pract. 2015 Sep;34(3):160-4. doi: 10.1016/j.krcp.2015.06.003. Epub 2015 Jul 26.

22.

Modulation of Aβ42 in vivo by γ-secretase modulator in primates and humans.

Ling IF, Golde TE, Galasko DR, Koo EH.

Alzheimers Res Ther. 2015 Aug 5;7(1):55. doi: 10.1186/s13195-015-0137-y. eCollection 2015.

23.

Cholestenoic acid, an endogenous cholesterol metabolite, is a potent γ-secretase modulator.

Jung JI, Price AR, Ladd TB, Ran Y, Park HJ, Ceballos-Diaz C, Smithson LA, Hochhaus G, Tang Y, Akula R, Ba S, Koo EH, Shapiro G, Felsenstein KM, Golde TE.

Mol Neurodegener. 2015 Jul 14;10:29. doi: 10.1186/s13024-015-0021-z.

24.

Rarity of the Alzheimer disease-protective APP A673T variant in the United States.

Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, Tschanz JT, Munger RG, Corcoran CD, Rogaeva E; Alzheimer's Disease Genetics Consortium, Lin CF, Dombroski BA, Cantwell LB, Partch A, Valladares O, Hakonarson H, St George-Hyslop P, Green RC, Goate AM, Foroud TM, Carney RM, Larson EB, Behrens TW, Kauwe JS, Haines JL, Farrer LA, Pericak-Vance MA, Mayeux R, Schellenberg GD; National Institute on Aging-Late-Onset Alzheimer’s Disease (NIA-LOAD) Family Study, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barmada M, Barnes LL, Beach TG, Becker JT, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buxbaum JD, Cairns NJ, Cao C, Carlson CS, Carroll SL, Chui HC, Clark DG, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Demirci FY, Dick M, Dickson DW, Duara R, Ertekin-Taner N, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Graff-Radford NR, Growdon JH, Hamilton RL, Hamilton-Nelson KL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Jun G, Kamboh MI, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lopez OL, Lunetta KL, Lyketsos CG, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam WM, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Murrell JR, Olichney JM, Parisi JE, Perry W, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L.

JAMA Neurol. 2015 Feb;72(2):209-16. doi: 10.1001/jamaneurol.2014.2157.

25.

Independent relationship between amyloid precursor protein (APP) dimerization and γ-secretase processivity.

Jung JI, Premraj S, Cruz PE, Ladd TB, Kwak Y, Koo EH, Felsenstein KM, Golde TE, Ran Y.

PLoS One. 2014 Oct 28;9(10):e111553. doi: 10.1371/journal.pone.0111553. eCollection 2014.

26.

The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes.

Nhan HS, Chiang K, Koo EH.

Acta Neuropathol. 2015 Jan;129(1):1-19. doi: 10.1007/s00401-014-1347-2. Epub 2014 Oct 7. Review.

27.

Effect of potent γ-secretase modulator in human neurons derived from multiple presenilin 1-induced pluripotent stem cell mutant carriers.

Liu Q, Waltz S, Woodruff G, Ouyang J, Israel MA, Herrera C, Sarsoza F, Tanzi RE, Koo EH, Ringman JM, Goldstein LS, Wagner SL, Yuan SH.

JAMA Neurol. 2014 Dec;71(12):1481-9. doi: 10.1001/jamaneurol.2014.2482.

28.

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.

Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, Baldwin CT, Jarvik GP, Crane PK, Rogaeva E, Barmada MM, Demirci FY, Cruchaga C, Kramer PL, Ertekin-Taner N, Hardy J, Graff-Radford NR, Green RC, Larson EB, St George-Hyslop PH, Buxbaum JD, Evans DA, Schneider JA, Lunetta KL, Kamboh MI, Saykin AJ, Reiman EM, De Jager PL, Bennett DA, Morris JC, Montine TJ, Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Martin ER, Haines JL, Mayeux RP, Farrer LA, Schellenberg GD, Pericak-Vance MA; Alzheimer Disease Genetics Consortium, Albert MS, Albin RL, Apostolova LG, Arnold SE, Barber R, Barnes LL, Beach TG, Becker JT, Beekly D, Bigio EH, Bowen JD, Boxer A, Burke JR, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carrasquillo MM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cribbs DH, Crocco EA, DeCarli C, DeKosky ST, Dick M, Dickson DW, Duara R, Faber KM, Fallon KB, Farlow MR, Ferris S, Frosch MP, Galasko DR, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Glass JD, Growdon JH, Hamilton RL, Harrell LE, Head E, Honig LS, Hulette CM, Hyman BT, Jicha GA, Jin LW, Karydas A, Kaye JA, Kim R, Koo EH, Kowall NW, Kramer JH, LaFerla FM, Lah JJ, Leverenz JB, Levey AI, Li G, Lieberman AP, Lin CF, Lopez OL, Lyketsos CG, Mack WJ, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Murrell JR, Olichney JM, Pankratz VS, Parisi JE, Paulson HL, Peskind E, Petersen RC, Pierce A, Poon WW, Potter H, Quinn JF, Raj A, Raskind M, Reisberg B, Ringman JM, Roberson ED, Rosen HJ, Rosenberg RN, Sano M, Schneider LS, Seeley WW, Smith AG, Sonnen JA, Spina S, Stern RA, Tanzi RE, Thornton-Wells TA, Trojanowski JQ, Troncoso JC, Valladares O, Van Deerlin VM, Van Eldik LJ, Vardarajan BN, Vinters HV, Vonsattel JP, Weintraub S, Welsh-Bohmer KA, Williamson J, Wishnek S, Woltjer RL, Wright CB, Younkin SG, Yu CE, Yu L.

JAMA Neurol. 2014 Nov;71(11):1394-404. doi: 10.1001/jamaneurol.2014.1491. Erratum in: JAMA Neurol. 2014 Nov;71(11):1457.

29.

Complex relationships between substrate sequence and sensitivity to alterations in γ-secretase processivity induced by γ-secretase modulators.

Jung JI, Ran Y, Cruz PE, Rosario AM, Ladd TB, Kukar TL, Koo EH, Felsenstein KM, Golde TE.

Biochemistry. 2014 Apr 1;53(12):1947-57. doi: 10.1021/bi401521t. Epub 2014 Mar 20.

30.

Specific disruption of hippocampal mossy fiber synapses in a mouse model of familial Alzheimer's disease.

Wilke SA, Raam T, Antonios JK, Bushong EA, Koo EH, Ellisman MH, Ghosh A.

PLoS One. 2014 Jan 13;9(1):e84349. doi: 10.1371/journal.pone.0084349. eCollection 2014.

31.

Emerging therapeutics for Alzheimer's disease.

Chiang K, Koo EH.

Annu Rev Pharmacol Toxicol. 2014;54:381-405. doi: 10.1146/annurev-pharmtox-011613-135932. Review.

PMID:
24392696
32.

The--YENPTY--domain of the amyloid precursor protein: much more than just endocytosis?

Nhan HS, Koo EH.

Bioessays. 2013 Oct;35(10):844. doi: 10.1002/bies.201300120. No abstract available.

PMID:
24078548
33.

Early BDNF treatment ameliorates cell loss in the entorhinal cortex of APP transgenic mice.

Nagahara AH, Mateling M, Kovacs I, Wang L, Eggert S, Rockenstein E, Koo EH, Masliah E, Tuszynski MH.

J Neurosci. 2013 Sep 25;33(39):15596-602. doi: 10.1523/JNEUROSCI.5195-12.2013.

34.

Activity-induced convergence of APP and BACE-1 in acidic microdomains via an endocytosis-dependent pathway.

Das U, Scott DA, Ganguly A, Koo EH, Tang Y, Roy S.

Neuron. 2013 Aug 7;79(3):447-60. doi: 10.1016/j.neuron.2013.05.035.

35.

γ-Secretase inhibitors and modulators.

Golde TE, Koo EH, Felsenstein KM, Osborne BA, Miele L.

Biochim Biophys Acta. 2013 Dec;1828(12):2898-907. doi: 10.1016/j.bbamem.2013.06.005. Epub 2013 Jun 17. Review.

36.

Steroids as γ-secretase modulators.

Jung JI, Ladd TB, Kukar T, Price AR, Moore BD, Koo EH, Golde TE, Felsenstein KM.

FASEB J. 2013 Sep;27(9):3775-85. doi: 10.1096/fj.12-225649. Epub 2013 May 28.

37.

Prevalence of cognitive impairment in Chinese: epidemiology of dementia in Singapore study.

Hilal S, Ikram MK, Saini M, Tan CS, Catindig JA, Dong YH, Lim LB, Ting EY, Koo EH, Cheung CY, Qiu A, Wong TY, Chen CL, Venketasubramanian N.

J Neurol Neurosurg Psychiatry. 2013 Jun;84(6):686-92. doi: 10.1136/jnnp-2012-304080. Epub 2013 Feb 5.

PMID:
23385846
38.

Asp664 cleavage of amyloid precursor protein induces tau phosphorylation by decreasing protein phosphatase 2A activity.

Park SS, Jung HJ, Kim YJ, Park TK, Kim C, Choi H, Mook-Jung IH, Koo EH, Park SA.

J Neurochem. 2012 Dec;123(5):856-65. doi: 10.1111/jnc.12032. Epub 2012 Oct 25.

39.

Amyloid precursor protein (APP) regulates synaptic structure and function.

Tyan SH, Shih AY, Walsh JJ, Maruyama H, Sarsoza F, Ku L, Eggert S, Hof PR, Koo EH, Dickstein DL.

Mol Cell Neurosci. 2012 Aug;51(1-2):43-52. doi: 10.1016/j.mcn.2012.07.009. Epub 2012 Aug 3.

40.

Acute recurrent pericarditis accompanied by graves' disease.

Koo EH, Kim SM, Park SM, Park JW, Kim EK, Lee GY, Chang SA, Lee SC, Choe YH.

Korean Circ J. 2012 Jun;42(6):419-22. doi: 10.4070/kcj.2012.42.6.419. Epub 2012 Jun 28.

41.

Novel late-onset Alzheimer disease loci variants associate with brain gene expression.

Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, Lincoln S, Bisceglio G, Georgescu C, Schultz D, Rakhshan F, Kolbert CP, Jen J, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD, Petersen RC, Graff-Radford NR, Dickson DW, Younkin SG, Ertekin-Taner N; Alzheimer's Disease Genetics Consortium (ADGC), Apostolova LG, Arnold SE, Baldwin CT, Barber R, Barmada MM, Beach T, Beecham GW, Beekly D, Bennett DA, Bigio EH, Bird TD, Blacker D, Boeve BF, Bowen JD, Boxer A, Burke JR, Buros J, Buxbaum JD, Cairns NJ, Cantwell LB, Cao C, Carlson CS, Carney RM, Carroll SL, Chui HC, Clark DG, Corneveaux J, Cotman CW, Crane PK, Cruchaga C, Cummings JL, De Jager PL, DeCarli C, DeKosky ST, Demirci FY, Diaz-Arrastia R, Dick M, Dombroski BA, Duara R, Ellis WD, Evans D, Faber KM, Fallon KB, Farlow MR, Ferris S, Foroud TM, Frosch M, Galasko DR, Gallins PJ, Ganguli M, Gearing M, Geschwind DH, Ghetti B, Gilbert JR, Gilman S, Giordani B, Glass JD, Goate AM, Green RC, Growdon JH, Hakonarson H, Hamilton RL, Hardy J, Harrell LE, Head E, Honig LS, Huentelman MJ, Hulette CM, Hyman BT, Jarvik GP, Jicha GA, Jin LW, Jun G, Kamboh MI, Karlawish J, Karydas A, Kauwe JS, Kaye JA, Kennedy N, Kim R, Koo EH, Kowall NW, Kramer P, Kukull WA, Lah JJ, Larson EB, Levey AI, Lieberman AP, Lopez OL, Lunetta KL, Mack WJ, Marson DC, Martin ER, Martiniuk F, Mash DC, Masliah E, McCormick WC, McCurry SM, McDavid AN, McKee AC, Mesulam M, Miller BL, Miller CA, Miller JW, Montine TJ, Morris JC, Myers AJ, Naj AC, Nowotny P, Parisi JE, Perl DP, Peskind E, Poon WW, Potter H, Quinn JF, Raj A, Rajbhandary RA, Raskind M, Reiman EM, Reisberg B, Reitz C, Ringman JM, Roberson ED, Rogaeva E, Rosenberg RN, Sano M, Saykin AJ, Schneider JA, Schneider LS, Seeley W, Shelanski ML, Slifer MA, Smith CD, Sonnen JA, Spina S, St George-Hyslop P, Stern RA, Tanzi RE, Trojanowski JQ, Troncoso JC, Tsuang DW, Van Deerlin VM, Vardarajan BN, Vinters HV, Vonsattel JP, Wang LS, Weintraub S, Welsh-Bohmer KA, Williamson J, Woltjer RL.

Neurology. 2012 Jul 17;79(3):221-8. doi: 10.1212/WNL.0b013e3182605801. Epub 2012 Jun 20.

42.

A case of hypereosinophilic syndrome presenting with multiorgan infarctions associated with disseminated intravascular coagulation.

Park SM, Park JW, Kim SM, Koo EH, Lee JY, Lee CS, Choi DC, Lee BJ.

Allergy Asthma Immunol Res. 2012 May;4(3):161-4. doi: 10.4168/aair.2012.4.3.161. Epub 2011 Dec 28.

43.

Recurrent ventricular tachycardia in malignant metastatic pheochromocytoma.

Park JW, Park SJ, Hur KY, Kim JH, Choi YL, Park SM, Kim SM, Koo EH, Kim JS.

Circulation. 2012 Mar 13;125(10):e435-8. doi: 10.1161/CIRCULATIONAHA.111.089607. No abstract available.

PMID:
22412096
44.

Pivotal role of the RanBP9-cofilin pathway in Aβ-induced apoptosis and neurodegeneration.

Woo JA, Jung AR, Lakshmana MK, Bedrossian A, Lim Y, Bu JH, Park SA, Koo EH, Mook-Jung I, Kang DE.

Cell Death Differ. 2012 Sep;19(9):1413-23. doi: 10.1038/cdd.2012.14. Epub 2012 Feb 24.

45.

Deletion of the amyloid precursor-like protein 2 (APLP2) does not affect hippocampal neuron morphology or function.

Midthune B, Tyan SH, Walsh JJ, Sarsoza F, Eggert S, Hof PR, Dickstein DL, Koo EH.

Mol Cell Neurosci. 2012 Apr;49(4):448-55. doi: 10.1016/j.mcn.2012.02.001. Epub 2012 Feb 13.

46.

Early and selective impairments in axonal transport kinetics of synaptic cargoes induced by soluble amyloid β-protein oligomers.

Tang Y, Scott DA, Das U, Edland SD, Radomski K, Koo EH, Roy S.

Traffic. 2012 May;13(5):681-93. doi: 10.1111/j.1600-0854.2012.01340.x. Epub 2012 Feb 27.

47.

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain.

Lakshmana MK, Hayes CD, Bennett SP, Bianchi E, Reddy KM, Koo EH, Kang DE.

FASEB J. 2012 May;26(5):2072-83. doi: 10.1096/fj.11-196709. Epub 2012 Jan 31. Erratum in: FASEB J. 2015 Mar;29(3):1124.

48.

Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.

Israel MA, Yuan SH, Bardy C, Reyna SM, Mu Y, Herrera C, Hefferan MP, Van Gorp S, Nazor KL, Boscolo FS, Carson CT, Laurent LC, Marsala M, Gage FH, Remes AM, Koo EH, Goldstein LS.

Nature. 2012 Jan 25;482(7384):216-20. doi: 10.1038/nature10821.

49.

Substrate sequence influences γ-secretase modulator activity, role of the transmembrane domain of the amyloid precursor protein.

Sagi SA, Lessard CB, Winden KD, Maruyama H, Koo JC, Weggen S, Kukar TL, Golde TE, Koo EH.

J Biol Chem. 2011 Nov 18;286(46):39794-803. doi: 10.1074/jbc.M111.277228. Epub 2011 Aug 25.

50.

Lysine 624 of the amyloid precursor protein (APP) is a critical determinant of amyloid β peptide length: support for a sequential model of γ-secretase intramembrane proteolysis and regulation by the amyloid β precursor protein (APP) juxtamembrane region.

Kukar TL, Ladd TB, Robertson P, Pintchovski SA, Moore B, Bann MA, Ren Z, Jansen-West K, Malphrus K, Eggert S, Maruyama H, Cottrell BA, Das P, Basi GS, Koo EH, Golde TE.

J Biol Chem. 2011 Nov 18;286(46):39804-12. doi: 10.1074/jbc.M111.274696. Epub 2011 Aug 25.

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