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Items: 1 to 50 of 92

1.

Akacid medical formulation induces apoptosis in myeloid and lymphatic leukemic cell lines in vitro and in vivo.

Neuwirt H, Wabnig E, Feistritzer C, Eder IE, Salvador C, Puhr M, Culig Z, Massoner P, Tiefenthaler M, Steurer M, Konwalinka G.

PLoS One. 2015 Feb 13;10(2):e0117806. doi: 10.1371/journal.pone.0117806. eCollection 2015.

2.

Interferon-gamma-mediated pathways are induced in human CD34(+) haematopoietic stem cells.

Kurz K, Gluhcheva Y, Zvetkova E, Konwalinka G, Fuchs D.

Immunobiology. 2010 Jun;215(6):452-7. doi: 10.1016/j.imbio.2009.08.007. Epub 2009 Sep 17.

PMID:
19765856
3.

Naturally occurring CD4+ CD25+ regulatory T cells modulate the haematopoietic potential of human stem cells in vitro.

Salvador C, Steurer M, Tzankov A, Wolf AM, Gastl G, Konwalinka G, Wolf D.

Br J Haematol. 2008 Sep;142(5):845-7. doi: 10.1111/j.1365-2141.2008.07190.x. Epub 2008 Jul 8. No abstract available.

PMID:
18637805
4.

Sphingosine-1-phosphate receptor type-1 agonism impairs blood dendritic cell chemotaxis and skin dendritic cell migration to lymph nodes under inflammatory conditions.

Gollmann G, Neuwirt H, Tripp CH, Mueller H, Konwalinka G, Heufler C, Romani N, Tiefenthaler M.

Int Immunol. 2008 Jul;20(7):911-23. doi: 10.1093/intimm/dxn050. Epub 2008 May 20.

PMID:
18495625
5.
6.

Phagocytosis of human retinal pigment epithelial cells: evidence of a diurnal rhythm, involvement of the cytoskeleton and interference of antiviral drugs.

Irschick EU, Haas G, Geiger M, Singer W, Ritsch-Marte M, Konwalinka G, Frick M, Gottinger W, Huemer HP.

Ophthalmic Res. 2006;38(3):164-74. Epub 2006 Feb 13.

PMID:
16479143
7.

Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells.

Bacher N, Tiefenthaler M, Sturm S, Stuppner H, Ausserlechner MJ, Kofler R, Konwalinka G.

Br J Haematol. 2006 Mar;132(5):615-22.

PMID:
16445836
8.

The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells.

Müller H, Hofer S, Kaneider N, Neuwirt H, Mosheimer B, Mayer G, Konwalinka G, Heufler C, Tiefenthaler M.

Eur J Immunol. 2005 Feb;35(2):533-45.

9.

Measurement of intracellular versus extracellular prostate-specific antigen levels in peripheral macrophages: a new approach to noninvasive diagnosis of prostate cancer.

Herwig R, Pelzer A, Horninger W, Rehder P, Klocker H, Ramoner R, Pinggera GM, Gozzi C, Konwalinka G, Bartsch G.

Clin Prostate Cancer. 2004 Dec;3(3):184-8.

PMID:
15636686
10.

Therapeutic effects of gemcitabine on cutaneous manifestations in an Adamantiades-Behçet's disease-like mouse model.

Sohn S, Lutz M, Kwon HJ, Konwalinka G, Lee S, Schirmer M.

Exp Dermatol. 2004 Oct;13(10):630-4.

PMID:
15447723
11.

Ability of PSA-positive circulating macrophages to detect prostate cancer.

Herwig R, Horninger W, Rehder P, Klocker H, Ramoner R, Thurnher M, Pinggera GM, Gozzi C, Konwalinka G, Bartsch G.

Prostate. 2005 Feb 15;62(3):290-8.

PMID:
15389786
12.

Large-vessel arteritis and myelodysplastic syndrome: report of two cases.

Steurer M, Fritsche G, Tzankov A, Gotwald T, Sturm W, Konwalinka G, Gruber J.

Eur J Haematol. 2004 Aug;73(2):128-33.

PMID:
15245512
13.

Possible role of cytokine-induced tryptophan degradation in anaemia of inflammation.

Weiss G, Schroecksnadel K, Mattle V, Winkler C, Konwalinka G, Fuchs D.

Eur J Haematol. 2004 Feb;72(2):130-4.

PMID:
14962250
14.

Changes of mitochondrial respiration, mitochondrial content and cell size after induction of apoptosis in leukemia cells.

Renner K, Amberger A, Konwalinka G, Kofler R, Gnaiger E.

Biochim Biophys Acta. 2003 Sep 23;1642(1-2):115-23.

15.

Apoptosis of CD34+ cells after incubation with sera of leukopenic patients with systemic lupus erythematosus.

Tiefenthaler M, Bacher N, Linert H, Mühlmann O, Hofer S, Sepp N, Amberger A, Geisen F, Obermoser G, Konwalinka G.

Lupus. 2003;12(6):471-8.

PMID:
12873050
16.

Delayed addition of deoxycytidine protects normal CD34+ cells against cytotoxicity of gemcitabine without compromising its activity against human leukemic cells.

Tiefenthaler M, Hohla F, Strasser-Wozak E, Bacher N, Mühlmann O, Wein W, Konwalinka G.

Stem Cells. 2003;21(3):266-71.

17.

In vitro studies on the immunosuppressive effect of 2',2'-difluorodeoxycytidine (dFdC) and its metabolite 2',2'-difluorodeoxyuridine (dFdU).

Tiefenthaler M, Hohla F, Irschick E, Strasser-Wozak E, Bacher N, Mühlmann O, Wein W, Konwalinka G.

Immunobiology. 2003;207(2):149-57.

PMID:
12675273
18.

Treatment of hairy cell leukemia with cladribine (2-chlorodeoxyadenosine) by subcutaneous bolus injection: a phase II study.

von Rohr A, Schmitz SF, Tichelli A, Hess U, Piguet D, Wernli M, Frickhofen N, Konwalinka G, Zulian G, Ghielmini M, Rufener B, Racine C, Fey MF, Cerny T, Betticher D, Tobler A; Swiss Group for Clinical Cancer Research (SAKK), Bern, Switzerland.

Ann Oncol. 2002 Oct;13(10):1641-9.

PMID:
12377655
19.

Increased lactate production follows loss of mitochondrial membrane potential during apoptosis of human leukaemia cells.

Tiefenthaler M, Amberger A, Bacher N, Hartmann BL, Margreiter R, Kofler R, Konwalinka G.

Br J Haematol. 2001 Sep;114(3):574-80.

PMID:
11552982
20.

Age dependent apoptosis and loss of rhabdosphincter cells.

Strasser H, Tiefenthaler M, Steinlechner M, Eder I, Bartsch G, Konwalinka G.

J Urol. 2000 Nov;164(5):1781-5.

PMID:
11025769
21.

New rearrangement pattern after treatment of hairy-cell leukemia with 2-chlorodeoxyadenosine.

Schirmer M, Haun M, Grünewald K, Geisen F, Hilbe W, Thaler J, Konwalinka G.

Acta Haematol. 2000;103(2):109-11.

PMID:
10838455
22.
23.

Cytotoxic activities of hypocretenolides from leontodon hispidus

Zidorn C, Stuppner H, Tiefenthaler M, Konwalinka G.

J Nat Prod. 1999 Nov;62(11):1594. No abstract available.

PMID:
10580925
24.

Gemcitabine--a novel immunosuppressive agent--prevents rejection in a rat cardiac transplantation model.

Margreiter R, Fischer M, Roberts K, Schmid T, Hittmair A, Schirmer M, Geisen F, Tiefenthaler M, Konwalinka G.

Transplantation. 1999 Oct 15;68(7):1051-3.

PMID:
10532549
25.

Cladribine treatment of a patient with hairy cell leukemia and concomitant multiple sclerosis.

Hilbe W, Berger T, Konwalinka G, Thaler J.

Acta Haematol. 1999;102(2):99-100.

PMID:
10529514
26.

Urinary incontinence in the elderly and age-dependent apoptosis of rhabdosphincter cells.

Strasser H, Tiefenthaler M, Steinlechner M, Bartsch G, Konwalinka G.

Lancet. 1999 Sep 11;354(9182):918-9.

PMID:
10489956
27.

Cytotoxic activities of hypocretenolides from Leontodon hispidus.

Zidorn C, Stuppner H, Tiefenthaler M, Konwalinka G.

J Nat Prod. 1999 Jul;62(7):984-7. Erratum in: J Nat Prod 1999 Nov;62(11):1594.

PMID:
10425121
28.

Lack of cross-resistance with gemcitabine and cytarabine in cladribine-resistant HL60 cells with elevated 5'-nucleotidase activity.

Schirmer M, Stegmann AP, Geisen F, Konwalinka G.

Exp Hematol. 1998 Dec;26(13):1223-8.

PMID:
9845378
29.

Interleukin 1beta mediates the modulatory effects of monocytes on LNCaP human prostate cancer cells.

Culig Z, Hobisch A, Herold M, Hittmair A, Thurnher M, Eder IE, Cronauer MV, Rieser C, Ramoner R, Bartsch G, Klocker H, Konwalinka G.

Br J Cancer. 1998 Oct;78(8):1004-11.

30.

Interferon-alpha for the treatment of elderly patients with chronic myeloid leukaemia.

Hilbe W, Apfelbeck U, Fridrik M, Bernhart M, Niessner H, Abbrederis K, Michlmayr G, Pont J, Linkesch W, Hausmaninger H, Arneitz K, Baldinger C, Duba C, Eisterer W, Greil R, Konwalinka G, Niederwieser D, Gastl G, Thaler J.

Leuk Res. 1998 Oct;22(10):881-6.

PMID:
9766747
31.

Antitumor effect of the nucleoside analogs 2-chlorodeoxyadenosine and 2',2'-difluorodeoxycytidine on human hepatoma HepG2 cells.

Graziadei I, Kelly T, Schirmer M, Geisen FH, Vogel W, Konwalinka G.

J Hepatol. 1998 Mar;28(3):504-9.

PMID:
9551690
32.

2-Chlorodeoxyadenosine (cladribine) in combination with low-dose cyclosporin prevents rejection after allogeneic heart and liver transplantation in the rat.

Schmid T, Hechenleitner P, Mark W, Fischer M, Roberts K, Geisen F, Klima G, Dietze O, Konwalinka G, Margreiter R.

Eur Surg Res. 1998;30(1):61-8.

PMID:
9493696
33.

A comparison of the antiproliferative properties of recombinant human IFN-alpha 2 and IFN-omega in human bone marrow culture.

Tiefenthaler M, Geisen F, Schirmer M, Konwalinka G.

J Interferon Cytokine Res. 1997 Jun;17(6):327-9.

PMID:
9197999
34.

Non-Hodgkin lymphoma with exclusive involvement of the heart and the gastrointestinal tract.

Zelger BG, Zelger BW, Konwalinka G, Mikuz G, Fend F.

Virchows Arch. 1997 May;430(5):427-30.

PMID:
9174633
35.

The safety profile of low-dose cladribine in refractory rheumatoid arthritis. A pilot trial.

Schirmer M, Mur E, Pfeiffer KP, Thaler J, Konwalinka G.

Scand J Rheumatol. 1997;26(5):376-9.

PMID:
9385350
36.

T cells and natural killer cells after treatment of hairy cell leukaemia with 2-chlorodeoxyadenosine.

Schirmer M, Hilbe W, Geisen F, Thaler J, Konwalinka G.

Acta Haematol. 1997;97(3):180-3.

PMID:
9066714
37.

Interferon-alpha-2C and LD ara-C for the treatment of patients with CML: results of the Austrian multi-center phase II study.

Thaler J, Hilbe W, Apfelbeck U, Linkesch W, Sill H, Seewann H, Pont J, Bernhart M, Stöger M, Niessner H, Abbrederis K, Geissler D, Hausmaninger H, Lin W, Ludwig H, Lang A, Duba C, Fluckinger T, Greil R, Grünewald K, Konwalinka G, Niederwieser D, Fridrik M.

Leuk Res. 1997 Jan;21(1):75-80.

PMID:
9029189
38.

Local application of antimycotics in mucormycosis cerebri: a case report.

Mohsenipour I, Schirmer M, Frank R, Geisen F, Semenitz E, zur Nedden D, Konwalinka G.

J Neurol Neurosurg Psychiatry. 1996 Nov;61(5):521-2.

39.

2-Chlorodeoxyadenosine (2-CdA) in chronic lymphocytic leukemia refractory to fludarabine?

Schirmer M, Michlmayr G, Geisen F, Konwalinka G.

Leukemia. 1996 Jul;10(7):1253-4. No abstract available.

PMID:
8684013
40.

2',2'-Difluorodeoxycytidine (gemcitabine) induces apoptosis in myeloma cell lines resistant to steroids and 2-chlorodeoxyadenosine (2-CdA).

Gruber J, Geisen F, Sgonc R, Egle A, Villunger A, Boeck G, Konwalinka G, Greil R.

Stem Cells. 1996 May;14(3):351-62.

41.

Inhibitory effects of the nucleoside analogue gemcitabine on prostatic carcinoma cells.

Cronauer MV, Klocker H, Talasz H, Geisen FH, Hobisch A, Radmayr C, Böck G, Culig Z, Schirmer M, Reissigl A, Bartsch G, Konwalinka G.

Prostate. 1996 Mar;28(3):172-81.

PMID:
8628720
42.

Growth-inhibitory effect of 2-CdA on myeloid CFU-GM progenitors in normal human long-term bone marrow cultures and its compensation by G-CSF or IL-3.

Petzer AL, Geisen FH, Bilgeri R, Zilian U, Haun M, Herold M, Braunsteiner H, Konwalinka G.

Exp Hematol. 1995 Jun;23(6):529-34.

PMID:
7539380
43.

Minimal residual disease in hairy-cell leukemia after treatment with 2-chlorodeoxyadenosine.

Konwalinka G, Schirmer M, Hilbe W, Fend F, Geisen F, Knoblechner A, Petzer A, Thaler J.

Blood Cells Mol Dis. 1995;21(2):142-51.

PMID:
8846043
44.

Normal granulocyte function but impaired monocyte function in a patient with aplastic anemia.

Zabernigg A, Hilbe W, Reinisch N, Eisterer W, Thaler J, Spötl L, Konwalinka G.

Acta Haematol. 1995;94(2):109-11.

PMID:
7484011
45.

Prevention with glucocorticoids of extrapancreatic tumour-hypoglycaemia as a result of increased 'big' insulin-like growth factor II.

Föger B, Zapf J, Lechleitner M, Konwalinka G, Patsch JR.

J Intern Med. 1994 Dec;236(6):692-3. No abstract available.

PMID:
7989907
46.

Evidence that 2-chlorodeoxyadenosine in combination with cyclosporine prevents rejection after allogeneic small bowel transplantation.

Oberhuber G, Schmid T, Thaler W, Kaltenbacher A, Schirmer M, Liliemark J, Herbst P, Geisen F, Margreiter R, Konwalinka G.

Transplantation. 1994 Sep 27;58(6):743-5. No abstract available.

PMID:
7940703
47.

The immunosuppressive substance 2-chloro-2-deoxyadenosine modulates lipoprotein metabolism in a murine macrophage cell line (P388 cells).

Lechleitner M, Auer B, Zilian U, Hoppichler F, Schirmer M, Föger B, Geisen F, Patsch JR, Konwalinka G.

Lipids. 1994 Sep;29(9):627-33.

PMID:
7815897
48.

Proliferating dendritic cell progenitors in human blood.

Romani N, Gruner S, Brang D, Kämpgen E, Lenz A, Trockenbacher B, Konwalinka G, Fritsch PO, Steinman RM, Schuler G.

J Exp Med. 1994 Jul 1;180(1):83-93.

49.

Fulminant hepatitis C virus infection.

Schirmer M, Vogel W, Thaler J, Grünewald K, Umlauft F, Geisen F, Zilian U, Konwalinka G.

Lancet. 1994 Jun 4;343(8910):1433. No abstract available.

PMID:
7910911
50.

2-Chlorodeoxyadenosine in combination with cyclosporine prevents rejection after allogeneic small bowel transplantation.

Schmid T, Oberhuber G, Thaler W, Kaltenbacher A, Herbst P, Margreiter R, Konwalinka G.

Transplant Proc. 1994 Jun;26(3):1614. No abstract available.

PMID:
7913269

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