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Items: 1 to 50 of 760

1.

The Role of Macrophages in the Biological Reaction to Wear Debris from Artificial Joints.

Nich C, Takakubo Y, Pajarinen J, Gallo J, Konttinen YT, Takagi M, Goodman SB.

J Long Term Eff Med Implants. 2016;26(4):303-309. doi: 10.1615/JLongTermEffMedImplants.2017011287.

PMID:
29199615
2.

Differentially Expressed in Chondrocytes 2 (DEC2) Increases the Expression of IL-1β and Is Abundantly Present in Synovial Membrane in Rheumatoid Arthritis.

Olkkonen J, Kouri VP, Hynninen J, Konttinen YT, Mandelin J.

PLoS One. 2015 Dec 28;10(12):e0145279. doi: 10.1371/journal.pone.0145279. eCollection 2015.

3.

Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis.

Barreto G, Soininen A, Ylinen P, Sandelin J, Konttinen YT, Nordström DC, Eklund KK.

Arthritis Res Ther. 2015 Dec 24;17:379. doi: 10.1186/s13075-015-0902-0.

4.

Establishment of Green Fluorescent Protein and Firefly Luciferase Expressing Mouse Primary Macrophages for In Vivo Bioluminescence Imaging.

Pajarinen J, Lin TH, Sato T, Loi F, Yao Z, Konttinen YT, Goodman SB.

PLoS One. 2015 Nov 10;10(11):e0142736. doi: 10.1371/journal.pone.0142736. eCollection 2015.

5.

Effects of S53P4 bioactive glass on osteoblastic cell and biomaterial surface interaction.

Pérez-Tanoira R, Kinnari TJ, Hyyrynen T, Soininen A, Pietola L, Tiainen VM, Konttinen YT, Aarnisalo AA.

J Mater Sci Mater Med. 2015 Oct;26(10):246. doi: 10.1007/s10856-015-5568-2. Epub 2015 Sep 28.

PMID:
26411442
6.

Effect of S53P4 bone substitute on staphylococcal adhesion and biofilm formation on other implant materials in normal and hypoxic conditions.

Pérez-Tanoira R, García-Pedrazuela M, Hyyrynen T, Soininen A, Aarnisalo A, Nieminen MT, Tiainen VM, Konttinen YT, Kinnari TJ.

J Mater Sci Mater Med. 2015 Sep;26(9):239. doi: 10.1007/s10856-015-5569-1. Epub 2015 Sep 24.

PMID:
26403279
7.

Diminished salivary epidermal growth factor secretion: a link between Sjögren's syndrome and autoimmune gastritis?

Koskenpato K, Ainola M, Przybyla B, Kouri VP, Virkki L, Koskenpato J, Ristimäki A, Konttinen YT.

Scand J Rheumatol. 2016;45(2):118-21. doi: 10.3109/03009742.2015.1072243. Epub 2015 Sep 23.

PMID:
26399281
8.

Inflammatory Mediators in Autoimmunity and Systemic Autoimmune Diseases.

Nakken B, Nagy G, Huszthy PC, Fossum E, Konttinen Y, Szodoray P.

Mediators Inflamm. 2015;2015:878712. doi: 10.1155/2015/878712. Epub 2015 Aug 5. No abstract available.

9.

Osteogenic differentiation of mesenchymal stromal cells in two-dimensional and three-dimensional cultures without animal serum.

Castrén E, Sillat T, Oja S, Noro A, Laitinen A, Konttinen YT, Lehenkari P, Hukkanen M, Korhonen M.

Stem Cell Res Ther. 2015 Sep 7;6:167. doi: 10.1186/s13287-015-0162-6.

10.

A bioactive hybrid three-dimensional tissue-engineering construct for cartilage repair.

Ainola M, Tomaszewski W, Ostrowska B, Wesolowska E, Wagner HD, Swieszkowski W, Sillat T, Peltola E, Konttinen YT.

J Biomater Appl. 2016 Jan;30(6):873-85. doi: 10.1177/0885328215604069. Epub 2015 Sep 4.

PMID:
26341661
11.

Distinctive expression pattern of interleukin-17 cytokine family members in colorectal cancer.

Al-Samadi A, Moossavi S, Salem A, Sotoudeh M, Tuovinen SM, Konttinen YT, Salo T, Bishehsari F.

Tumour Biol. 2016 Feb;37(2):1609-15. doi: 10.1007/s13277-015-3941-x. Epub 2015 Aug 25.

PMID:
26304506
12.

Selected Aspects in the Pathogenesis of Autoimmune Diseases.

Nagy G, Huszthy PC, Fossum E, Konttinen Y, Nakken B, Szodoray P.

Mediators Inflamm. 2015;2015:351732. doi: 10.1155/2015/351732. Epub 2015 Aug 2. Review.

13.

Autoinflammation Around AES Total Ankle Replacement Implants.

Koivu H, Takakubo Y, Mackiewicz Z, Al-Samadi A, Soininen A, Peled N, Kukis M, Trokovic N, Konttinen YT.

Foot Ankle Int. 2015 Dec;36(12):1455-62. doi: 10.1177/1071100715596608. Epub 2015 Jul 28.

PMID:
26219907
14.

Epithelial Cell Apoptosis in Recurrent Aphthous Ulcers.

Al-Samadi A, Drozd A, Salem A, Hietanen J, Häyrinen-Immonen R, Konttinen YT.

J Dent Res. 2015 Jul;94(7):928-35. doi: 10.1177/0022034515581012. Epub 2015 Apr 10.

PMID:
25861801
15.

The cost-effectiveness of biologics for the treatment of rheumatoid arthritis: a systematic review.

Joensuu JT, Huoponen S, Aaltonen KJ, Konttinen YT, Nordström D, Blom M.

PLoS One. 2015 Mar 17;10(3):e0119683. doi: 10.1371/journal.pone.0119683. eCollection 2015. Review.

16.

Activation of histamine H3 receptor decreased cytoplasmic Ca(2+) imaging during electrical stimulation in the skeletal myotubes.

Chen Y, Paavola J, Stegajev V, Stark H, Chazot PL, Wen JG, Konttinen YT.

Eur J Pharmacol. 2015 May 5;754:173-8. doi: 10.1016/j.ejphar.2015.02.035. Epub 2015 Mar 3.

PMID:
25746421
17.

Human beta-defensin-3 producing cells in septic implant loosening.

Levón J, Al-Samadi A, Mackiewicz Z, Coer A, Trebse R, Waris E, Konttinen YT.

J Mater Sci Mater Med. 2015 Feb;26(2):98. doi: 10.1007/s10856-015-5440-4. Epub 2015 Feb 6.

PMID:
25655501
18.

Rates of serious infections and malignancies among patients with rheumatoid arthritis receiving either tumor necrosis factor inhibitor or rituximab therapy.

Aaltonen KJ, Joensuu JT, Virkki L, Sokka T, Aronen P, Relas H, Valleala H, Rantalaiho V, Pirilä L, Puolakka K, Uusitalo T, Blom M, Konttinen YT, Nordström D.

J Rheumatol. 2015 Mar;42(3):372-8. doi: 10.3899/jrheum.140853. Epub 2015 Jan 15.

PMID:
25593230
19.

Identification of histamine receptor subtypes in skeletal myogenesis.

Chen Y, Stegaev V, Kouri VP, Sillat T, Chazot PL, Stark H, Wen JG, Konttinen YT.

Mol Med Rep. 2015 Apr;11(4):2624-30. doi: 10.3892/mmr.2014.3073. Epub 2014 Dec 10.

20.

Identification of Sjögren's syndrome oral fluid biomarker candidates following high-abundance protein depletion.

Deutsch O, Krief G, Konttinen YT, Zaks B, Wong DT, Aframian DJ, Palmon A.

Rheumatology (Oxford). 2015 May;54(5):884-90. doi: 10.1093/rheumatology/keu405. Epub 2014 Oct 21.

PMID:
25339641
21.

Valsalva leak point pressure-associated Q-tip angle and simple female stress urinary incontinence symptoms.

Chen Y, Wen JG, Shen H, Lv YT, Wang Y, Wang QW, Konttinen YT.

Int Urol Nephrol. 2014 Nov;46(11):2103-8. doi: 10.1007/s11255-014-0772-4. Epub 2014 Oct 15.

PMID:
25315465
22.

Activation of histamine H4 receptor inhibits TNFα/IMD-0354-induced apoptosis in human salivary NS-SV-AC cells.

Stegajev V, Kouri VP, Salem A, Rozov S, Stark H, Nordström DC, Konttinen YT.

Apoptosis. 2014 Dec;19(12):1702-11. doi: 10.1007/s10495-014-1036-6.

PMID:
25239604
23.

Histamine H4 receptor in oral lichen planus.

Salem A, Al-Samadi A, Stegajev V, Stark H, Häyrinen-Immonen R, Ainola M, Hietanen J, Konttinen YT.

Oral Dis. 2015 Apr;21(3):378-85. doi: 10.1111/odi.12290. Epub 2014 Oct 8.

PMID:
25207698
24.

Sjögren's syndome and extragonadal sex steroid formation: a clue to a better disease control?

Konttinen YT, Stegajev V, Al-Samadi A, Porola P, Hietanen J, Ainola M.

J Steroid Biochem Mol Biol. 2015 Jan;145:237-44. doi: 10.1016/j.jsbmb.2014.08.014. Epub 2014 Aug 23. Review.

PMID:
25158020
25.

Modulation of mouse macrophage polarization in vitro using IL-4 delivery by osmotic pumps.

Pajarinen J, Tamaki Y, Antonios JK, Lin TH, Sato T, Yao Z, Takagi M, Konttinen YT, Goodman SB.

J Biomed Mater Res A. 2015 Apr;103(4):1339-45. doi: 10.1002/jbm.a.35278. Epub 2014 Jul 22.

26.

Characterization of macrophage polarizing cytokines in the aseptic loosening of total hip replacements.

Jämsen E, Kouri VP, Olkkonen J, Cör A, Goodman SB, Konttinen YT, Pajarinen J.

J Orthop Res. 2014 Sep;32(9):1241-6. doi: 10.1002/jor.22658. Epub 2014 Jun 5.

27.

Increased beta 2 defensin in recurrent aphthous ulcer.

Al-Samadi A, Salem A, Ainola M, Hietanen J, Häyrinen-Immonen R, Konttinen YT.

Oral Dis. 2015 Apr;21(3):292-8. doi: 10.1111/odi.12262. Epub 2014 Jun 25.

PMID:
24854020
28.

Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner.

Sipilä K, Haag S, Denessiouk K, Käpylä J, Peters EC, Denesyuk A, Hansen U, Konttinen Y, Johnson MS, Holmdahl R, Heino J.

FASEB J. 2014 Aug;28(8):3758-68. doi: 10.1096/fj.13-247767. Epub 2014 May 13.

PMID:
24823363
29.

Label-free imaging of adipogenesis by coherent anti-stokes Raman scattering microscopy.

Isomäki A, Sillat T, Ainola M, Liljeström M, Konttinen YT, Hukkanen M.

Methods Mol Biol. 2014;1142:189-201. doi: 10.1007/978-1-4939-0404-4_16.

PMID:
24706284
30.

Sample processing, protocol, and statistical analysis of the time-of-flight secondary ion mass spectrometry (ToF-SIMS) of protein, cell, and tissue samples.

Barreto G, Soininen A, Sillat T, Konttinen YT, Kaivosoja E.

Methods Mol Biol. 2014;1142:177-88. doi: 10.1007/978-1-4939-0404-4_15.

PMID:
24706283
31.

Cell-tissue interactions in osteoarthritic human hip joint articular cartilage.

Huttu MR, Puhakka J, Mäkelä JT, Takakubo Y, Tiitu V, Saarakkala S, Konttinen YT, Kiviranta I, Korhonen RK.

Connect Tissue Res. 2014 Aug;55(4):282-91. doi: 10.3109/03008207.2014.912645. Epub 2014 Apr 30.

PMID:
24702070
32.

Expression of cathepsin K in periodontitis and in gingival fibroblasts.

Beklen A, Al-Samadi A, Konttinen YT.

Oral Dis. 2015 Mar;21(2):163-9. doi: 10.1111/odi.12230. Epub 2014 Mar 24.

PMID:
24661326
33.

Osteoarthritic cartilage lesions in the bovine patellar groove: a macroscopic, histological and immunohistological analysis.

Heinola T, Sukura A, Virkki LM, Sillat T, Lekszycki T, Konttinen YT.

Vet J. 2014 Apr;200(1):88-95. doi: 10.1016/j.tvjl.2014.01.026. Epub 2014 Feb 7.

PMID:
24581814
34.

Osteogenic differentiation on DLC-PDMS-h surface.

Soininen A, Kaivosoja E, Sillat T, Virtanen S, Konttinen YT, Tiainen VM.

J Biomed Mater Res B Appl Biomater. 2014 Oct;102(7):1462-72. doi: 10.1002/jbm.b.33125. Epub 2014 Feb 27.

PMID:
24574187
35.

Contributions of human tissue analysis to understanding the mechanisms of loosening and osteolysis in total hip replacement.

Gallo J, Vaculova J, Goodman SB, Konttinen YT, Thyssen JP.

Acta Biomater. 2014 Jun;10(6):2354-66. doi: 10.1016/j.actbio.2014.02.003. Epub 2014 Feb 10. Review.

36.

Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement.

Goodman SB, Gibon E, Pajarinen J, Lin TH, Keeney M, Ren PG, Nich C, Yao Z, Egashira K, Yang F, Konttinen YT.

J R Soc Interface. 2014 Jan 29;11(93):20130962. doi: 10.1098/rsif.2013.0962. Print 2014 Apr 6. Review.

37.

BMP-2 induces ATF4 phosphorylation in chondrocytes through a COX-2/PGE2 dependent signaling pathway.

Li TF, Yukata K, Yin G, Sheu T, Maruyama T, Jonason JH, Hsu W, Zhang X, Xiao G, Konttinen YT, Chen D, O'Keefe RJ.

Osteoarthritis Cartilage. 2014 Mar;22(3):481-9. doi: 10.1016/j.joca.2013.12.020. Epub 2014 Jan 11.

38.

Back-side wear in HexLoc cups clinico-radiological, immunohistopathological, finite element, and retrieval analysis studies.

Kawaji H, Koistinen A, Korhonen R, Lappalainen R, Lohman M, Soininen A, Gomez Barrena E, Konttinen YT, Ylinen P, Tallroth K.

J Long Term Eff Med Implants. 2014;24(4):319-31.

PMID:
25747033
39.

Innate immunity sensors participating in pathophysiology of joint diseases: a brief overview.

Gallo J, Raska M, Konttinen YT, Nich C, Goodman SB.

J Long Term Eff Med Implants. 2014;24(4):297-317.

40.

Innate immune reactions in septic and aseptic osteolysis around hip implants.

Pajarinen J, Jamsen E, Konttinen YT, Goodman SB.

J Long Term Eff Med Implants. 2014;24(4):283-96.

41.

Macrophage polarization and activation in response to implant debris: influence by "particle disease" and "ion disease".

Konttinen YT, Pajarinen J, Takakubo Y, Gallo J, Nich C, Takagi M, Goodman SB.

J Long Term Eff Med Implants. 2014;24(4):267-81.

42.

Joint replacement surgery and the innate immune system.

Goodman SB, Konttinen YT, Takagi M.

J Long Term Eff Med Implants. 2014;24(4):253-7.

43.

Role of innate immune sensors, TLRs, and NALP3 in rheumatoid arthritis and osteoarthritis.

Takakubo Y, Barreto G, Konttinen YT, Oki H, Takagi M.

J Long Term Eff Med Implants. 2014;24(4):243-51.

PMID:
25747027
44.

Toll-like receptors in human chondrocytes and osteoarthritic cartilage.

Sillat T, Barreto G, Clarijs P, Soininen A, Ainola M, Pajarinen J, Korhonen M, Konttinen YT, Sakalyte R, Hukkanen M, Ylinen P, Nordström DC.

Acta Orthop. 2013 Dec;84(6):585-92. doi: 10.3109/17453674.2013.854666. Epub 2013 Nov 18.

45.

Neutrophils produce interleukin-17B in rheumatoid synovial tissue.

Kouri VP, Olkkonen J, Ainola M, Li TF, Björkman L, Konttinen YT, Mandelin J.

Rheumatology (Oxford). 2014 Jan;53(1):39-47. doi: 10.1093/rheumatology/ket309. Epub 2013 Sep 19.

PMID:
24056520
46.

Laminin production and basement membrane deposition by mesenchymal stem cells upon adipogenic differentiation.

Noro A, Sillat T, Virtanen I, Ingerpuu S, Bäck N, Konttinen YT, Korhonen M.

J Histochem Cytochem. 2013 Oct;61(10):719-30. doi: 10.1369/0022155413502055. Epub 2013 Jul 30.

47.

No evidence of long-term benefits of arthroscopicacromioplasty in the treatment of shoulder impingement syndrome: Five-year results of a randomised controlled trial.

Ketola S, Lehtinen J, Rousi T, Nissinen M, Huhtala H, Konttinen YT, Arnala I.

Bone Joint Res. 2013 Jul 1;2(7):132-9. doi: 10.1302/2046-3758.27.2000163. Print 2013.

48.

IL-17C and its receptor IL-17RA/IL-17RE identify human oral epithelial cell as an inflammatory cell in recurrent aphthous ulcer.

Al-Samadi A, Kouri VP, Salem A, Ainola M, Kaivosoja E, Barreto G, Konttinen YT, Hietanen J, Häyrinen-Immonen R.

J Oral Pathol Med. 2014 Feb;43(2):117-24. doi: 10.1111/jop.12095. Epub 2013 Jul 3.

PMID:
23834281
49.

The response of macrophages to titanium particles is determined by macrophage polarization.

Pajarinen J, Kouri VP, Jämsen E, Li TF, Mandelin J, Konttinen YT.

Acta Biomater. 2013 Nov;9(11):9229-40. doi: 10.1016/j.actbio.2013.06.027. Epub 2013 Jul 1.

PMID:
23827094
50.

Histamine transport and metabolism are deranged in salivary glands in Sjogren's syndrome.

Stegaev V, Nies AT, Porola P, Mieliauskaite D, Sánchez-Jiménez F, Urdiales JL, Sillat T, Schwelberger HG, Chazot PL, Katebe M, Mackiewicz Z, Konttinen YT, Nordström DC.

Rheumatology (Oxford). 2013 Sep;52(9):1599-608. doi: 10.1093/rheumatology/ket188. Epub 2013 May 24.

PMID:
23709238

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