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Items: 36

1.

Safety and efficacy of nintedanib in idiopathic pulmonary fibrosis: A real-life observational study in Greece.

Tzouvelekis A, Karampitsakos T, Kontou M, Granitsas A, Malliou I, Anagnostopoulos A, Ntolios P, Tzilas V, Bouros E, Steiropoulos P, Chrysikos S, Dimakou K, Koulouris N, Bouros D.

Pulm Pharmacol Ther. 2018 Apr;49:61-66. doi: 10.1016/j.pupt.2018.01.006. Epub 2018 Jan 31.

PMID:
29366978
2.

Proteomic Analysis of Human Angiogenin Interactions Reveals Cytoplasmic PCNA as a Putative Binding Partner.

Chatzileontiadou DSM, Samiotaki M, Alexopoulou AN, Cotsiki M, Panayotou G, Stamatiadi M, Balatsos NAA, Leonidas DD, Kontou M.

J Proteome Res. 2017 Oct 6;16(10):3606-3622. doi: 10.1021/acs.jproteome.7b00335. Epub 2017 Sep 8.

PMID:
28777577
3.

Studies on the essential intramolecular interaction between the A1 and A2 domains of von Willebrand factor.

Karoulia Z, Papadopoulos G, Nomikos M, Thanassoulas A, Papadopoulou TC, Nounesis G, Kontou M, Stathopoulos C, Leonidas DD.

Protein Pept Lett. 2013 Feb;20(2):231-40.

PMID:
22973838
4.

Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase.

Spanou C, Veskoukis AS, Kerasioti T, Kontou M, Angelis A, Aligiannis N, Skaltsounis AL, Kouretas D.

PLoS One. 2012;7(3):e32214. doi: 10.1371/journal.pone.0032214. Epub 2012 Mar 2.

5.

3'-axial CH2 OH substitution on glucopyranose does not increase glycogen phosphorylase inhibitory potency. QM/MM-PBSA calculations suggest why.

Manta S, Xipnitou A, Kiritsis C, Kantsadi AL, Hayes JM, Skamnaki VT, Lamprakis C, Kontou M, Zoumpoulakis P, Zographos SE, Leonidas DD, Komiotis D.

Chem Biol Drug Des. 2012 May;79(5):663-73. doi: 10.1111/j.1747-0285.2012.01349.x. Epub 2012 Mar 7.

PMID:
22296957
6.

The σ-hole phenomenon of halogen atoms forms the structural basis of the strong inhibitory potency of C5 halogen substituted glucopyranosyl nucleosides towards glycogen phosphorylase b.

Kantsadi AL, Hayes JM, Manta S, Skamnaki VT, Kiritsis C, Psarra AM, Koutsogiannis Z, Dimopoulou A, Theofanous S, Nikoleousakos N, Zoumpoulakis P, Kontou M, Papadopoulos G, Zographos SE, Komiotis D, Leonidas DD.

ChemMedChem. 2012 Apr;7(4):722-32. doi: 10.1002/cmdc.201100533. Epub 2012 Jan 20.

PMID:
22267166
7.

Quantification of nucleotide-activated sialic acids by a combination of reduction and fluorescent labeling.

Galuska SP, Geyer H, Weinhold B, Kontou M, Röhrich RC, Bernard U, Gerardy-Schahn R, Reutter W, Münster-Kühnel A, Geyer R.

Anal Chem. 2010 Jun 1;82(11):4591-8. doi: 10.1021/ac100627e.

PMID:
20429516
8.

N-Propionylmannosamine-induced over-expression and secretion of thioredoxin leads to neurite outgrowth of PC12 cells.

Horstkorte R, Reinke S, Bauer C, Reutter W, Kontou M.

Biochem Biophys Res Commun. 2010 May 7;395(3):296-300. doi: 10.1016/j.bbrc.2010.03.113. Epub 2010 Mar 21.

PMID:
20331970
9.

The C-terminal region of HPNAP activates neutrophils and promotes their adhesion to endothelial cells.

Kottakis F, Befani C, Asiminas A, Kontou M, Koliakos G, Choli-Papadopoulou T.

Helicobacter. 2009 Jun;14(3):177-9. doi: 10.1111/j.1523-5378.2009.00678.x.

PMID:
19702847
10.

Inhibitor design for ribonuclease A: the binding of two 5'-phosphate uridine analogues.

Tsirkone VG, Dossi K, Drakou C, Zographos SE, Kontou M, Leonidas DD.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Jul 1;65(Pt 7):671-7. doi: 10.1107/S1744309109021423. Epub 2009 Jun 27.

11.

Beyond glycosylation: sialic acid precursors act as signaling molecules and are involved in cellular control of differentiation of PC12 cells.

Kontou M, Weidemann W, Bork K, Horstkorte R.

Biol Chem. 2009 Jul;390(7):575-9. doi: 10.1515/BC.2009.058. Review.

PMID:
19361277
12.

Metabolism of galactose in the brain and liver of rats and its conversion into glutamate and other amino acids.

Roser M, Josic D, Kontou M, Mosetter K, Maurer P, Reutter W.

J Neural Transm (Vienna). 2009 Feb;116(2):131-9. doi: 10.1007/s00702-008-0166-9. Epub 2008 Dec 17.

PMID:
19089315
13.

Impaired synthesis of heme oxygenase-1 in Fanconi anemia cells can be rescued by transfection of Fanconi wild-type cDNA.

Kontou M, Hirsch-Kauffmann M, Schweiger M.

Biol Chem. 2008 Oct;389(10):1327-32. doi: 10.1515/BC.2008.151.

PMID:
18713020
14.

Case-mix adjustment approach to benchmarking prevalence rates of nosocomial infection in hospitals in Cyprus and Greece.

Kritsotakis EI, Dimitriadis I, Roumbelaki M, Vounou E, Kontou M, Papakyriakou P, Koliou-Mazeri M, Varthalitis I, Vrouchos G, Troulakis G, Gikas A.

Infect Control Hosp Epidemiol. 2008 Aug;29(8):685-92. doi: 10.1086/588704.

PMID:
18643744
15.

The key enzyme of sialic acid biosynthesis (GNE) promotes neurite outgrowth of PC12 cells.

Kontou M, Weidemann W, Bauer C, Reutter W, Horstkorte R.

Neuroreport. 2008 Aug 6;19(12):1239-42. doi: 10.1097/WNR.0b013e32830b368a.

PMID:
18628673
16.

Sialic acid metabolism is involved in the regulation of gene expression during neuronal differentiation of PC12 cells.

Kontou M, Bauer C, Reutter W, Horstkorte R.

Glycoconj J. 2008 Apr;25(3):237-44. doi: 10.1007/s10719-008-9104-1. Epub 2008 Jan 29.

PMID:
18228138
17.

Experimental approaches to interfere with the polysialylation of the neural cell adhesion molecule in vitro and in vivo.

Bork K, Gagiannis D, Orthmann A, Weidemann W, Kontou M, Reutter W, Horstkorte R.

J Neurochem. 2007 Nov;103 Suppl 1:65-71. Review.

18.

Molecular cloning and biochemical characterization of VIM-12, a novel hybrid VIM-1/VIM-2 metallo-beta-lactamase from a Klebsiella pneumoniae clinical isolate, reveal atypical substrate specificity.

Kontou M, Pournaras S, Kristo I, Ikonomidis A, Maniatis AN, Stathopoulos C.

Biochemistry. 2007 Nov 13;46(45):13170-8. Epub 2007 Oct 18.

PMID:
17944487
19.

Structural determinants of tissue tropism and in vivo pathogenicity for the parvovirus minute virus of mice.

Kontou M, Govindasamy L, Nam HJ, Bryant N, Llamas-Saiz AL, Foces-Foces C, Hernando E, Rubio MP, McKenna R, Almendral JM, Agbandje-McKenna M.

J Virol. 2005 Sep;79(17):10931-43.

20.

First cluster of vancomycin-resistant Enterococcus faecalis isolates in Cyprus.

Daikos GL, Triantafyllopoulou P, Syriopoulou V, Bakatzouni-Pieridou D, Kontou M, Theodoulou M, Tofas P, Petrikkos G.

Clin Microbiol Infect. 2005 Mar;11(3):232-4.

21.

Multicentre surveillance of antibiotic resistance in nosocomial Staphylococcus aureus in Cyprus.

Gourni M, Kontou M, Hadjipanayiotou C, Protopapa P.

East Mediterr Health J. 2001 Jul-Sep;7(4-5):744-9.

22.

Thioredoxin, a regulator of gene expression.

Kontou M, Will RD, Adelfalk C, Wittig R, Poustka A, Hirsch-Kauffmann M, Schweiger M.

Oncogene. 2004 Mar 18;23(12):2146-52.

PMID:
14730345
23.

Suboptimal action of NF-kappaB in Fanconi anemia cells results from low levels of thioredoxin.

Kontou M, Adelfalk C, Hirsch-Kauffmann M, Schweiger M.

Biol Chem. 2003 Oct-Nov;384(10-11):1501-7.

PMID:
14669993
24.

Physical and functional interaction of the Werner syndrome protein with poly-ADP ribosyl transferase.

Adelfalk C, Kontou M, Hirsch-Kauffmann M, Schweiger M.

FEBS Lett. 2003 Nov 6;554(1-2):55-8.

25.

The cellular control enzyme polyADP ribosyl transferase is eliminated in cultured Fanconi anemia fibroblasts at confluency.

Ramirez MH, Adelfalk C, Kontou M, Hirsch-Kauffmann M, Schweiger M.

Biol Chem. 2003 Jan;384(1):169-74.

PMID:
12674511
26.

Overexpressed thioredoxin compensates Fanconi anemia related chromosomal instability.

Kontou M, Adelfalk C, Ramirez MH, Ruppitsch W, Hirsch-Kauffmann M, Schweiger M.

Oncogene. 2002 Apr 4;21(15):2406-12.

27.

Colorectal polyp detection with virtual colonoscopy (computed tomographic colonography); the reliability of the method.

Xynopoulos D, Stasinopoulou M, Dimitroulopoulos D, Tsamakides K, Arhavlis E, Kontou M, Tavernaraki A, Paraskevas E.

Hepatogastroenterology. 2002 Jan-Feb;49(43):124-7.

PMID:
11941935
28.

Crystal structure of Fab198, an efficient protector of the acetylcholine receptor against myasthenogenic antibodies.

Poulas K, Eliopoulos E, Vatzaki E, Navaza J, Kontou M, Oikonomakos N, Acharya KR, Tzartos SJ.

Eur J Biochem. 2001 Jul;268(13):3685-93.

29.

Primary melanoma of the oesophagus treated endoscopically. A case report.

Xinopoulos D, Archavlis EM, Kontou M, Tsamakidis K, Dimitroulopoulos D, Soutos D, Paraskevas EM.

Dig Liver Dis. 2001 Apr;33(3):254-7.

PMID:
11407671
30.

A novel arginine vasopressin-neurophysin II mutation causes autosomal dominant neurohypophyseal diabetes insipidus and morphologic pituitary changes.

Skordis N, Patsalis PC, Hettinger JA, Kontou M, Herakleous E, Krishnamani MR, Phillips JA 3rd.

Horm Res. 2000;53(5):239-45.

PMID:
11150885
31.

The crystal structure of the Fab fragment of a rat monoclonal antibody against the main immunogenic region of the human muscle acetylcholine receptor.

Kontou M, Leonidas DD, Vatzaki EH, Tsantili P, Mamalaki A, Oikonomakos NG, Acharya KR, Tzartos SJ.

Eur J Biochem. 2000 Apr;267(8):2389-97.

33.

N-acetyl-beta-D-glucopyranosylamine: a potent T-state inhibitor of glycogen phosphorylase. A comparison with alpha-D-glucose.

Oikonomakos NG, Kontou M, Zographos SE, Watson KA, Johnson LN, Bichard CJ, Fleet GW, Acharya KR.

Protein Sci. 1995 Dec;4(12):2469-77.

34.

Glucose analogue inhibitors of glycogen phosphorylase: from crystallographic analysis to drug prediction using GRID force-field and GOLPE variable selection.

Watson KA, Mitchell EP, Johnson LN, Cruciani G, Son JC, Bichard CJ, Fleet GW, Oikonomakos NG, Kontou M, Zographos SE.

Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):458-72.

PMID:
15299833
35.

The design of potential antidiabetic drugs: experimental investigation of a number of beta-D-glucose analogue inhibitors of glycogen phosphorylase.

Oikonomakos NG, Kontou M, Zographos SE, Tsitoura HS, Johnson LN, Watson KA, Mitchell EP, Fleet GW, Son JC, Bichard CJ, et al.

Eur J Drug Metab Pharmacokinet. 1994 Jul-Sep;19(3):185-92.

PMID:
7867660
36.

Design of inhibitors of glycogen phosphorylase: a study of alpha- and beta-C-glucosides and 1-thio-beta-D-glucose compounds.

Watson KA, Mitchell EP, Johnson LN, Son JC, Bichard CJ, Orchard MG, Fleet GW, Oikonomakos NG, Leonidas DD, Kontou M, et al.

Biochemistry. 1994 May 17;33(19):5745-58.

PMID:
8180201

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