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Items: 1 to 50 of 89

1.

Plasma membrane architecture protects Candida albicans from killing by copper.

Douglas LM, Konopka JB.

PLoS Genet. 2019 Jan 11;15(1):e1007911. doi: 10.1371/journal.pgen.1007911. eCollection 2019 Jan.

2.

Genetic Analysis of NDT80 Family Transcription Factors in Candida albicans Using New CRISPR-Cas9 Approaches.

Min K, Biermann A, Hogan DA, Konopka JB.

mSphere. 2018 Nov 21;3(6). pii: e00545-18. doi: 10.1128/mSphere.00545-18.

3.

Phagocytes from Mice Lacking the Sts Phosphatases Have an Enhanced Antifungal Response to Candida albicans.

Frank D, Naseem S, Russo GL, Li C, Parashar K, Konopka JB, Carpino N.

MBio. 2018 Jul 17;9(4). pii: e00782-18. doi: 10.1128/mBio.00782-18.

4.

Erratum for Mor et al., "Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids".

Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, Sallans L, Desai PB, Wiederhold NP, Fothergill AW, Kirkpatrick WR, Patterson T, Wong LH, Sinha S, Giaever G, Nislow C, Flaherty P, Pan X, Cesar GV, de Melo Tavares P, Frases S, Miranda K, Rodrigues ML, Luberto C, Nimrichter L, Del Poeta M.

MBio. 2018 Mar 13;9(2). pii: e00188-18. doi: 10.1128/mBio.00188-18. No abstract available.

5.

MCC/Eisosomes Regulate Cell Wall Synthesis and Stress Responses in Fungi.

Foderaro JE, Douglas LM, Konopka JB.

J Fungi (Basel). 2017 Nov 3;3(4). pii: E61. doi: 10.3390/jof3040061. Review.

6.

Modulating Host Signaling Pathways to Promote Resistance to Infection by Candida albicans.

Carpino N, Naseem S, Frank DM, Konopka JB.

Front Cell Infect Microbiol. 2017 Nov 21;7:481. doi: 10.3389/fcimb.2017.00481. eCollection 2017. Review.

7.

N-Acetylglucosamine Metabolism Promotes Survival of Candida albicans in the Phagosome.

Vesely EM, Williams RB, Konopka JB, Lorenz MC.

mSphere. 2017 Sep 6;2(5). pii: e00357-17. doi: 10.1128/mSphere.00357-17. eCollection 2017 Sep-Oct.

8.

An N-acetylglucosamine transporter required for arbuscular mycorrhizal symbioses in rice and maize.

Nadal M, Sawers R, Naseem S, Bassin B, Kulicke C, Sharman A, An G, An K, Ahern KR, Romag A, Brutnell TP, Gutjahr C, Geldner N, Roux C, Martinoia E, Konopka JB, Paszkowski U.

Nat Plants. 2017 May 26;3:17073. doi: 10.1038/nplants.2017.73.

9.

Regulation of Hyphal Growth and N-Acetylglucosamine Catabolism by Two Transcription Factors in Candida albicans.

Naseem S, Min K, Spitzer D, Gardin J, Konopka JB.

Genetics. 2017 May;206(1):299-314. doi: 10.1534/genetics.117.201491. Epub 2017 Mar 27.

10.

cAMP-independent signal pathways stimulate hyphal morphogenesis in Candida albicans.

Parrino SM, Si H, Naseem S, Groudan K, Gardin J, Konopka JB.

Mol Microbiol. 2017 Mar;103(5):764-779. doi: 10.1111/mmi.13588. Epub 2016 Dec 19.

11.

Eisosomes promote the ability of Sur7 to regulate plasma membrane organization in Candida albicans.

Wang HX, Douglas LM, Veselá P, Rachel R, Malinsky J, Konopka JB.

Mol Biol Cell. 2016 May 15;27(10):1663-75. doi: 10.1091/mbc.E16-01-0065. Epub 2016 Mar 23.

12.

Plasma membrane organization promotes virulence of the human fungal pathogen Candida albicans.

Douglas LM, Konopka JB.

J Microbiol. 2016 Mar;54(3):178-91. doi: 10.1007/s12275-016-5621-y. Epub 2016 Feb 27. Review.

13.

Flavodoxin-Like Proteins Protect Candida albicans from Oxidative Stress and Promote Virulence.

Li L, Naseem S, Sharma S, Konopka JB.

PLoS Pathog. 2015 Sep 1;11(9):e1005147. doi: 10.1371/journal.ppat.1005147. eCollection 2015 Sep.

14.

N-acetylglucosamine Regulates Virulence Properties in Microbial Pathogens.

Naseem S, Konopka JB.

PLoS Pathog. 2015 Jul 30;11(7):e1004947. doi: 10.1371/journal.ppat.1004947. eCollection 2015 Jul. Review. No abstract available.

15.

Identification of a New Class of Antifungals Targeting the Synthesis of Fungal Sphingolipids.

Mor V, Rella A, Farnoud AM, Singh A, Munshi M, Bryan A, Naseem S, Konopka JB, Ojima I, Bullesbach E, Ashbaugh A, Linke MJ, Cushion M, Collins M, Ananthula HK, Sallans L, Desai PB, Wiederhold NP, Fothergill AW, Kirkpatrick WR, Patterson T, Wong LH, Sinha S, Giaever G, Nislow C, Flaherty P, Pan X, Cesar GV, de Melo Tavares P, Frases S, Miranda K, Rodrigues ML, Luberto C, Nimrichter L, Del Poeta M.

MBio. 2015 Jun 23;6(3):e00647. doi: 10.1128/mBio.00647-15. Erratum in: MBio. 2018 Mar 13;9(2):.

16.

Raft-like membrane domains in pathogenic microorganisms.

Farnoud AM, Toledo AM, Konopka JB, Del Poeta M, London E.

Curr Top Membr. 2015;75:233-68. doi: 10.1016/bs.ctm.2015.03.005. Epub 2015 Apr 11. Review.

17.

The mitochondrial protein Mcu1 plays important roles in carbon source utilization, filamentation, and virulence in Candida albicans.

Guan G, Wang H, Liang W, Cao C, Tao L, Naseem S, Konopka JB, Wang Y, Huang G.

Fungal Genet Biol. 2015 Aug;81:150-9. doi: 10.1016/j.fgb.2015.01.006. Epub 2015 Jan 24.

PMID:
25626172
18.

Hyphal growth in Candida albicans does not require induction of hyphal-specific gene expression.

Naseem S, Araya E, Konopka JB.

Mol Biol Cell. 2015 Mar 15;26(6):1174-87. doi: 10.1091/mbc.E14-08-1312. Epub 2015 Jan 21.

19.

Protection from systemic Candida albicans infection by inactivation of the Sts phosphatases.

Naseem S, Frank D, Konopka JB, Carpino N.

Infect Immun. 2015 Feb;83(2):637-45. doi: 10.1128/IAI.02789-14. Epub 2014 Nov 24.

20.

Fungal membrane organization: the eisosome concept.

Douglas LM, Konopka JB.

Annu Rev Microbiol. 2014;68:377-93. doi: 10.1146/annurev-micro-091313-103507. Epub 2014 Jun 18. Review.

PMID:
25002088
21.

The MARVEL domain protein Nce102 regulates actin organization and invasive growth of Candida albicans.

Douglas LM, Wang HX, Konopka JB.

MBio. 2013 Nov 26;4(6):e00723-13. doi: 10.1128/mBio.00723-13.

22.

Distinct roles of cell wall biogenesis in yeast morphogenesis as revealed by multivariate analysis of high-dimensional morphometric data.

Okada H, Ohnuki S, Roncero C, Konopka JB, Ohya Y.

Mol Biol Cell. 2014 Jan;25(2):222-33. doi: 10.1091/mbc.E13-07-0396. Epub 2013 Nov 20.

23.

N-acetylglucosamine (GlcNAc) triggers a rapid, temperature-responsive morphogenetic program in thermally dimorphic fungi.

Gilmore SA, Naseem S, Konopka JB, Sil A.

PLoS Genet. 2013;9(9):e1003799. doi: 10.1371/journal.pgen.1003799. Epub 2013 Sep 19.

24.

Clathrin- and Arp2/3-independent endocytosis in the fungal pathogen Candida albicans.

Epp E, Nazarova E, Regan H, Douglas LM, Konopka JB, Vogel J, Whiteway M.

MBio. 2013 Aug 27;4(5):e00476-13. doi: 10.1128/mBio.00476-13.

25.

N-acetylglucosamine (GlcNAc) functions in cell signaling.

Konopka JB.

Scientifica (Cairo). 2012 Jan 1;2012. pii: 489208. Epub 2012 Oct 23.

26.
27.

Novel roles for GlcNAc in cell signaling.

Naseem S, Parrino SM, Buenten DM, Konopka JB.

Commun Integr Biol. 2012 Mar 1;5(2):156-9. doi: 10.4161/cib.19034.

28.

Membrane Compartment Occupied by Can1 (MCC) and Eisosome Subdomains of the Fungal Plasma Membrane.

Douglas LM, Wang HX, Li L, Konopka JB.

Membranes (Basel). 2011 Dec 1;1(4):394-411. doi: 10.3390/membranes1040394.

29.

Sur7 promotes plasma membrane organization and is needed for resistance to stressful conditions and to the invasive growth and virulence of Candida albicans.

Douglas LM, Wang HX, Keppler-Ross S, Dean N, Konopka JB.

MBio. 2011 Dec 27;3(1). pii: e00254-11. doi: 10.1128/mBio.00254-11. Print 2012.

30.

N-acetylglucosamine (GlcNAc) induction of hyphal morphogenesis and transcriptional responses in Candida albicans are not dependent on its metabolism.

Naseem S, Gunasekera A, Araya E, Konopka JB.

J Biol Chem. 2011 Aug 19;286(33):28671-80. doi: 10.1074/jbc.M111.249854. Epub 2011 Jun 23.

31.

The Candida albicans Sur7 protein is needed for proper synthesis of the fibrillar component of the cell wall that confers strength.

Wang HX, Douglas LM, Aimanianda V, Latgé JP, Konopka JB.

Eukaryot Cell. 2011 Jan;10(1):72-80. doi: 10.1128/EC.00167-10. Epub 2010 Nov 29.

32.

Strategies for isolating constitutively active and dominant-negative pheromone receptor mutants in yeast.

Dosil M, Konopka JB.

Methods Enzymol. 2010;485:329-48. doi: 10.1016/B978-0-12-381296-4.00019-1.

33.

Recognition of yeast by murine macrophages requires mannan but not glucan.

Keppler-Ross S, Douglas L, Konopka JB, Dean N.

Eukaryot Cell. 2010 Nov;9(11):1776-87. doi: 10.1128/EC.00156-10. Epub 2010 Sep 10.

34.

Identification of GIG1, a GlcNAc-induced gene in Candida albicans needed for normal sensitivity to the chitin synthase inhibitor nikkomycin Z.

Gunasekera A, Alvarez FJ, Douglas LM, Wang HX, Rosebrock AP, Konopka JB.

Eukaryot Cell. 2010 Oct;9(10):1476-83. doi: 10.1128/EC.00178-10. Epub 2010 Jul 30.

35.

A photostable green fluorescent protein variant for analysis of protein localization in Candida albicans.

Zhang C, Konopka JB.

Eukaryot Cell. 2010 Jan;9(1):224-6. doi: 10.1128/EC.00327-09. Epub 2009 Nov 13.

37.

BAR domain proteins Rvs161 and Rvs167 contribute to Candida albicans endocytosis, morphogenesis, and virulence.

Douglas LM, Martin SW, Konopka JB.

Infect Immun. 2009 Sep;77(9):4150-60. doi: 10.1128/IAI.00683-09. Epub 2009 Jul 13.

38.

Identification of amino acids at two dimer interface regions of the alpha-factor receptor (Ste2).

Wang HX, Konopka JB.

Biochemistry. 2009 Aug 4;48(30):7132-9. doi: 10.1021/bi900424h.

PMID:
19588927
39.

The Sur7 protein regulates plasma membrane organization and prevents intracellular cell wall growth in Candida albicans.

Alvarez FJ, Douglas LM, Rosebrock A, Konopka JB.

Mol Biol Cell. 2008 Dec;19(12):5214-25. doi: 10.1091/mbc.E08-05-0479. Epub 2008 Sep 17.

40.

Saccharomyces cerevisiae Afr1 protein is a protein phosphatase 1/Glc7-targeting subunit that regulates the septin cytoskeleton during mating.

Bharucha JP, Larson JR, Konopka JB, Tatchell K.

Eukaryot Cell. 2008 Aug;7(8):1246-55. doi: 10.1128/EC.00024-08. Epub 2008 Jun 13.

41.
42.

Sterol-rich plasma membrane domains in fungi.

Alvarez FJ, Douglas LM, Konopka JB.

Eukaryot Cell. 2007 May;6(5):755-63. Epub 2007 Mar 16. Review. No abstract available.

43.

Functional expression of mammalian receptors and membrane channels in different cells.

Eifler N, Duckely M, Sumanovski LT, Egan TM, Oksche A, Konopka JB, Lüthi A, Engel A, Werten PJ.

J Struct Biol. 2007 Aug;159(2):179-93. Epub 2007 Feb 3.

PMID:
17368047
44.

Identification of an N-acetylglucosamine transporter that mediates hyphal induction in Candida albicans.

Alvarez FJ, Konopka JB.

Mol Biol Cell. 2007 Mar;18(3):965-75. Epub 2006 Dec 27.

46.

DEP-domain-mediated regulation of GPCR signaling responses.

Ballon DR, Flanary PL, Gladue DP, Konopka JB, Dohlman HG, Thorner J.

Cell. 2006 Sep 22;126(6):1079-93.

47.

Septin function in yeast model systems and pathogenic fungi.

Douglas LM, Alvarez FJ, McCreary C, Konopka JB.

Eukaryot Cell. 2005 Sep;4(9):1503-12. Review. No abstract available.

48.
49.

Comparison of class A and D G protein-coupled receptors: common features in structure and activation.

Eilers M, Hornak V, Smith SO, Konopka JB.

Biochemistry. 2005 Jun 28;44(25):8959-75.

50.

Successful expression of a functional yeast G-protein-coupled receptor (Ste2) in mammalian cells.

Yin D, Gavi S, Shumay E, Duell K, Konopka JB, Malbon CC, Wang HY.

Biochem Biophys Res Commun. 2005 Apr 1;329(1):281-7.

PMID:
15721304

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