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Modified Isolation Selective Cerebral Perfusion Technique for Intracardiac Disease with Mobile Atheroma.

Miura S, Wada T, Konno M, Iba Y, Maruyama R, Hatta E, Yamada A, Kurimoto Y.

Ann Vasc Dis. 2019 Jun 25;12(2):222-224. doi: 10.3400/


A Hydrogen Peroxide Activatable Gemcitabine Prodrug for the Selective Treatment of Pancreatic Ductal Adenocarcinoma.

Matsushita K, Okuda T, Mori S, Konno M, Eguchi H, Asai A, Koseki J, Iwagami Y, Yamada D, Akita H, Asaoka T, Noda T, Kawamoto K, Gotoh K, Kobayashi S, Kasahara Y, Morihiro K, Satoh T, Doki Y, Mori M, Ishii H, Obika S.

ChemMedChem. 2019 Jun 17. doi: 10.1002/cmdc.201900324. [Epub ahead of print]


Characterization of the human E2F4 promoter region and its response to 12-O-tetradecanoylphorbol-13-acetate.

Hamada H, Goto Y, Arakawa J, Murayama E, Ogawa Y, Konno M, Oyama T, Asai M, Sato A, Tanuma SI, Uchiumi F.

J Biochem. 2019 Jun 14. pii: mvz047. doi: 10.1093/jb/mvz047. [Epub ahead of print]


Reduction in HPV 16/18 prevalence among young women following HPV vaccine introduction in a highly vaccinated district, Japan, 2008-2017.

Karube A, Saito F, Nakamura E, Shitara A, Ono N, Konno M, Tamura D, Nagao D.

J Rural Med. 2019 May;14(1):48-57. doi: 10.2185/jrm.2986. Epub 2019 May 30.


Significant Epitranscriptomes in Heterogeneous Cancer.

Konno M, Taniguchi M, Ishii H.

Cancer Sci. 2019 Jun 11. doi: 10.1111/cas.14095. [Epub ahead of print]


A Coordinated Wheeled Gas Pipeline Robot Chain System Based on Visible Light Relay Communication and Illuminance Assessment.

Zhao W, Kamezaki M, Yoshida K, Yamaguchi K, Konno M, Onuki A, Sugano S.

Sensors (Basel). 2019 May 20;19(10). pii: E2322. doi: 10.3390/s19102322.


Thoracic Endovascular Aortic Repair on Zone 2 Landing for Type B Aortic Dissection.

Miura S, Kurimoto Y, Maruyama R, Wada T, Konno M, Iba Y, Hatta E, Yamada A.

Ann Vasc Surg. 2019 May 8. pii: S0890-5096(19)30272-9. doi: 10.1016/j.avsg.2019.02.017. [Epub ahead of print]


Engineered Functional Recovery of Microbial Rhodopsin without Retinal-Binding Lysine.

Yamauchi Y, Konno M, Yamada D, Yura K, Inoue K, Béjà O, Kandori H.

Photochem Photobiol. 2019 May 8. doi: 10.1111/php.13114. [Epub ahead of print]


Role of mycorrhizal associations in tree spatial distribution patterns based on size class in an old-growth forest.

Sasaki T, Konno M, Hasegawa Y, Imaji A, Terabaru M, Nakamura R, Ohira N, Matsukura K, Seiwa K.

Oecologia. 2019 Apr;189(4):971-980. doi: 10.1007/s00442-019-04376-2. Epub 2019 Mar 27.


Direct Analysis of Incorporation of an Anticancer Drug into DNA at Single-Molecule Resolution.

Ohshiro T, Komoto Y, Konno M, Koseki J, Asai A, Ishii H, Taniguchi M.

Sci Rep. 2019 Mar 7;9(1):3886. doi: 10.1038/s41598-019-40504-x.


Enhanced infectivity of strains of Helicobacter pylori isolated from children compared with parental strains.

Zaman C, Osaki T, Furuta Y, Hojo F, Yonezawa H, Konno M, Kurata S, Hanawa T, Kamiya S.

J Med Microbiol. 2019 Apr;68(4):633-641. doi: 10.1099/jmm.0.000918. Epub 2019 Feb 26.


Mitochondrial pyruvate carrier 1 expression controls cancer epithelial-mesenchymal transition and radioresistance.

Takaoka Y, Konno M, Koseki J, Colvin H, Asai A, Tamari K, Satoh T, Mori M, Doki Y, Ogawa K, Ishii H.

Cancer Sci. 2019 Apr;110(4):1331-1339. doi: 10.1111/cas.13980.


Design, synthesis and biological evaluation of low molecular weight CXCR4 ligands.

Sakyiamah MM, Kobayakawa T, Fujino M, Konno M, Narumi T, Tanaka T, Nomura W, Yamamoto N, Murakami T, Tamamura H.

Bioorg Med Chem. 2019 Mar 15;27(6):1130-1138. doi: 10.1016/j.bmc.2019.02.013. Epub 2019 Feb 6.


AI for medical use.

Konno M, Ishii H.

Oncotarget. 2019 Jan 4;10(2):86-87. doi: 10.18632/oncotarget.26556. eCollection 2019 Jan 4. No abstract available.


Preoperative cerebral and renal oxygen saturation and clinical outcomes in pediatric patients with congenital heart disease.

Saito J, Takekawa D, Kawaguchi J, Suganuma T, Konno M, Noguchi S, Tokita T, Hashiba E, Hirota K.

J Clin Monit Comput. 2019 Jan 21. doi: 10.1007/s10877-019-00260-9. [Epub ahead of print]


A Computed Tomographic Assessment of Tracheostomy Tube Placement in Patients with Chronic Neurological Disorders: The Prevention of Tracheoarterial Fistula.

Tateyama M, Konno M, Takano R, Chida K, Rikimaru H, Chida K.

Intern Med. 2019 May 1;58(9):1251-1256. doi: 10.2169/internalmedicine.1158-18. Epub 2019 Jan 10.


Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2.

Asai A, Koseki J, Konno M, Nishimura T, Gotoh N, Satoh T, Doki Y, Mori M, Ishii H.

Heliyon. 2018 Dec 17;4(12):e01021. doi: 10.1016/j.heliyon.2018.e01021. eCollection 2018 Dec.


Polyamine flux suppresses histone lysine demethylases and enhances ID1 expression in cancer stem cells.

Tamari K, Konno M, Asai A, Koseki J, Hayashi K, Kawamoto K, Murai N, Matsufuji S, Isohashi F, Satoh T, Goto N, Tanaka S, Doki Y, Mori M, Ogawa K, Ishii H.

Cell Death Discov. 2018 Nov 13;4:104. doi: 10.1038/s41420-018-0117-7. eCollection 2018.


Pharmacology of Parsabiv® (etelcalcetide, ONO-5163/AMG 416), a novel allosteric modulator of the calcium-sensing receptor, for secondary hyperparathyroidism in hemodialysis patients.

Harada K, Fujioka A, Konno M, Inoue A, Yamada H, Hirota Y.

Eur J Pharmacol. 2019 Jan 5;842:139-145. doi: 10.1016/j.ejphar.2018.10.021. Epub 2018 Oct 19.


A Convolutional Neural Network Uses Microscopic Images to Differentiate between Mouse and Human Cell Lines and Their Radioresistant Clones.

Toratani M, Konno M, Asai A, Koseki J, Kawamoto K, Tamari K, Li Z, Sakai D, Kudo T, Satoh T, Sato K, Motooka D, Okuzaki D, Doki Y, Mori M, Ogawa K, Ishii H.

Cancer Res. 2018 Dec 1;78(23):6703-6707. doi: 10.1158/0008-5472.CAN-18-0653. Epub 2018 Sep 25.


Carbon ion beam radioresistant rodent cells are sensitized to trifluorothymidine exposure.

Baek SJ, Sato K, Nishida N, Koseki J, Hayashi K, Kawamoto K, Konno M, Doki Y, Mori M, Ogawa K, Ishii H.

Oncol Lett. 2018 Sep;16(3):3389-3393. doi: 10.3892/ol.2018.9004. Epub 2018 Jun 21.


Cell-free culture conditioned medium elicits pancreatic β cell lineage-specific epigenetic reprogramming in mice.

Kawamoto K, Ohashi T, Konno M, Nishida N, Koseki J, Matsui H, Sakai D, Kudo T, Eguchi H, Satoh T, Doki Y, Mori M, Ishii H.

Oncol Lett. 2018 Sep;16(3):3255-3259. doi: 10.3892/ol.2018.9008. Epub 2018 Jun 21.


Poly(ethylene glycol)-poly(lysine) block copolymer-ubenimex conjugate targets aminopeptidase N and exerts an antitumor effect in hepatocellular carcinoma stem cells.

Toshiyama R, Konno M, Eguchi H, Takemoto H, Noda T, Asai A, Koseki J, Haraguchi N, Ueda Y, Matsushita K, Asukai K, Ohashi T, Iwagami Y, Yamada D, Sakai D, Asaoka T, Kudo T, Kawamoto K, Gotoh K, Kobayashi S, Satoh T, Doki Y, Nishiyama N, Mori M, Ishii H.

Oncogene. 2019 Jan;38(2):244-260. doi: 10.1038/s41388-018-0406-x. Epub 2018 Aug 8.


Simple Radiometric Determination of Strontium-90 in Seawater Using Measurement of Yttrium-90 Decay Time Following Iron-Barium Co-precipitation.

Konno M, Takagai Y.

Anal Sci. 2018 Nov 10;34(11):1277-1283. doi: 10.2116/analsci.18P145. Epub 2018 Jul 20.


c-Met affects gemcitabine resistance during carcinogenesis in a mouse model of pancreatic cancer.

Noguchi K, Konno M, Eguchi H, Kawamoto K, Mukai R, Nishida N, Koseki J, Wada H, Akita H, Satoh T, Marubashi S, Nagano H, Doki Y, Mori M, Ishii H.

Oncol Lett. 2018 Aug;16(2):1892-1898. doi: 10.3892/ol.2018.8793. Epub 2018 May 24.


The mitochondrial one-carbon metabolic pathway is associated with patient survival in pancreatic cancer.

Noguchi K, Konno M, Koseki J, Nishida N, Kawamoto K, Yamada D, Asaoka T, Noda T, Wada H, Gotoh K, Sakai D, Kudo T, Satoh T, Eguchi H, Doki Y, Mori M, Ishii H.

Oncol Lett. 2018 Aug;16(2):1827-1834. doi: 10.3892/ol.2018.8795. Epub 2018 May 24.


A distinct abundant group of microbial rhodopsins discovered using functional metagenomics.

Pushkarev A, Inoue K, Larom S, Flores-Uribe J, Singh M, Konno M, Tomida S, Ito S, Nakamura R, Tsunoda SP, Philosof A, Sharon I, Yutin N, Koonin EV, Kandori H, Béjà O.

Nature. 2018 Jun;558(7711):595-599. doi: 10.1038/s41586-018-0225-9. Epub 2018 Jun 20.


Oligomeric states of microbial rhodopsins determined by high-speed atomic force microscopy and circular dichroic spectroscopy.

Shibata M, Inoue K, Ikeda K, Konno M, Singh M, Kataoka C, Abe-Yoshizumi R, Kandori H, Uchihashi T.

Sci Rep. 2018 May 29;8(1):8262. doi: 10.1038/s41598-018-26606-y.


Fetal hepatocyte-derived culture medium elicits adipocyte differentiation to bile duct cell lineages in a mouse model.

Ogawa H, Konno M, Kawamoto K, Nishida N, Koseki J, Mizushima T, Satoh T, Eguchi H, Doki Y, Mori M, Ishii H.

Biomed Rep. 2018 May;8(5):497-499. doi: 10.3892/br.2018.1080. Epub 2018 Mar 21.


Association of iron metabolic enzyme hepcidin expression levels with the prognosis of patients with pancreatic cancer.

Toshiyama R, Konno M, Eguchi H, Asai A, Noda T, Koseki J, Asukai K, Ohashi T, Matsushita K, Iwagami Y, Yamada D, Asaoka T, Wada H, Kawamoto K, Gotoh K, Kudo T, Satoh T, Doki Y, Mori M, Ishii H.

Oncol Lett. 2018 May;15(5):8125-8133. doi: 10.3892/ol.2018.8357. Epub 2018 Mar 26.


Accuracy of digital models generated by conventional impression/plaster-model methods and intraoral scanning.

Tomita Y, Uechi J, Konno M, Sasamoto S, Iijima M, Mizoguchi I.

Dent Mater J. 2018 Jul 29;37(4):628-633. doi: 10.4012/dmj.2017-208. Epub 2018 Apr 17.


Clinical effectiveness of four neuraminidase inhibitors (oseltamivir, zanamivir, laninamivir, and peramivir) for children with influenza A and B in the 2014-2015 to 2016-2017 influenza seasons in Japan.

Ishiguro N, Koseki N, Kaiho M, Ariga T, Kikuta H, Oba K, Togashi T, Morita K, Inagawa A, Okamura A, Yamazaki S, Shida S, Konno M, Kawamura N, Ishizaka A, Takada K, Tsubakihara K, Nagano N, Shibata M, Furuyama H, Matsuzono Y, Koike A, Murashita M, Hatae Y, Arioka H, Yamanaka T, Watanabe T, Tabata Y, Kumita Y, Hazama K, Akutsu Y, Aoyagi H, Tobise C, Azuma K, Yasoshima K, Sawada Y, Uetsuji K, Tsuchida A, Tsuchiyama A, Yasuda K, Odagawa Y, Yoshioka M.

J Infect Chemother. 2018 Jun;24(6):449-457. doi: 10.1016/j.jiac.2018.01.013. Epub 2018 Feb 24.


Oncogene c-Myc promotes epitranscriptome m6A reader YTHDF1 expression in colorectal cancer.

Nishizawa Y, Konno M, Asai A, Koseki J, Kawamoto K, Miyoshi N, Takahashi H, Nishida N, Haraguchi N, Sakai D, Kudo T, Hata T, Matsuda C, Mizushima T, Satoh T, Doki Y, Mori M, Ishii H.

Oncotarget. 2017 Dec 21;9(7):7476-7486. doi: 10.18632/oncotarget.23554. eCollection 2018 Jan 26.


Euglena gracilis Z and its carbohydrate storage substance relieve arthritis symptoms by modulating Th17 immunity.

Suzuki K, Nakashima A, Igarashi M, Saito K, Konno M, Yamazaki N, Takimoto H.

PLoS One. 2018 Feb 1;13(2):e0191462. doi: 10.1371/journal.pone.0191462. eCollection 2018.


Hypoxia stimulates the cytoplasmic localization of oncogenic long noncoding RNA LINC00152 in colorectal cancer.

Nishizawa Y, Konno M, Asai A, Koseki J, Kawamoto K, Miyoshi N, Takahashi H, Nishida N, Haraguchi N, Sakai D, Kudo T, Hata T, Matsuda C, Mizushima T, Satoh T, Doki Y, Mori M, Ishii H.

Int J Oncol. 2018 Feb;52(2):453-460. doi: 10.3892/ijo.2017.4218. Epub 2017 Dec 7.


The epitranscriptome m6A writer METTL3 promotes chemo- and radioresistance in pancreatic cancer cells.

Taketo K, Konno M, Asai A, Koseki J, Toratani M, Satoh T, Doki Y, Mori M, Ishii H, Ogawa K.

Int J Oncol. 2018 Feb;52(2):621-629. doi: 10.3892/ijo.2017.4219. Epub 2017 Dec 7.


Computational trans-omics approach characterised methylomic and transcriptomic involvements and identified novel therapeutic targets for chemoresistance in gastrointestinal cancer stem cells.

Konno M, Matsui H, Koseki J, Asai A, Kano Y, Kawamoto K, Nishida N, Sakai D, Kudo T, Satoh T, Doki Y, Mori M, Ishii H.

Sci Rep. 2018 Jan 17;8(1):899. doi: 10.1038/s41598-018-19284-3.


Enzymes of the one-carbon folate metabolism as anticancer targets predicted by survival rate analysis.

Koseki J, Konno M, Asai A, Colvin H, Kawamoto K, Nishida N, Sakai D, Kudo T, Satoh T, Doki Y, Mori M, Ishii H.

Sci Rep. 2018 Jan 10;8(1):303. doi: 10.1038/s41598-017-18456-x.


Mitochondrial pyruvate carrier modulates the epithelial-mesenchymal transition in cholangiocarcinoma.

Ohashi T, Eguchi H, Kawamoto K, Konno M, Asai A, Colvin H, Ueda Y, Takaoka H, Iwagami Y, Yamada D, Asaoka T, Noda T, Wada H, Gotoh K, Kobayashi S, Koseki J, Satoh T, Ogawa K, Doki Y, Mori M, Ishii H.

Oncol Rep. 2018 Mar;39(3):1276-1282. doi: 10.3892/or.2017.6172. Epub 2017 Dec 20.


Psychological and psychiatric symptoms of terminally ill patients with cancer and their family caregivers in the home-care setting: A nation-wide survey from the perspective of bereaved family members in Japan.

Kobayakawa M, Ogawa A, Konno M, Kurata A, Hamano J, Morita T, Kizawa Y, Tsuneto S, Shima Y, Aoyama M, Miyashita M.

J Psychosom Res. 2017 Dec;103:127-132. doi: 10.1016/j.jpsychores.2017.10.012. Epub 2017 Oct 23.


Discovery of Peripheral κ-Opioid Receptor Agonists as Novel Analgesics.

Suzuki S, Sugawara Y, Inada H, Tsuji R, Inoue A, Tanimura R, Shimozono R, Konno M, Ohyama T, Higashi E, Sakai C, Kawai K.

Chem Pharm Bull (Tokyo). 2017;65(11):1085-1088. doi: 10.1248/cpb.c17-00555.


Oral administration of Euglena gracilis Z and its carbohydrate storage substance provides survival protection against influenza virus infection in mice.

Nakashima A, Suzuki K, Asayama Y, Konno M, Saito K, Yamazaki N, Takimoto H.

Biochem Biophys Res Commun. 2017 Dec 9;494(1-2):379-383. doi: 10.1016/j.bbrc.2017.09.167. Epub 2017 Sep 30.


MicroRNA profiles involved in trifluridine resistance.

Tsunekuni K, Konno M, Asai A, Koseki J, Kobunai T, Takechi T, Doki Y, Mori M, Ishii H.

Oncotarget. 2017 May 23;8(32):53017-53027. doi: 10.18632/oncotarget.18078. eCollection 2017 Aug 8.


Engineering Tumour Cell-Binding Synthetic Polymers with Sensing Dense Transporters Associated with Aberrant Glutamine Metabolism.

Yamada N, Honda Y, Takemoto H, Nomoto T, Matsui M, Tomoda K, Konno M, Ishii H, Mori M, Nishiyama N.

Sci Rep. 2017 Jul 20;7(1):6077. doi: 10.1038/s41598-017-06438-y.


Relationships Between Gum Chewing and Stroop Test: A Pilot Study.

Kawakami Y, Takeda T, Konno M, Suzuki Y, Kawano Y, Ozawa T, Kondo Y, Sakatani K.

Adv Exp Med Biol. 2017;977:221-226. doi: 10.1007/978-3-319-55231-6_30.


PFC Blood Oxygenation Changes in Four Different Cognitive Tasks.

Takeda T, Kawakami Y, Konno M, Matsuda Y, Nishino M, Suzuki Y, Kawano Y, Nakajima K, Ozawa T, Kondo Y, Sakatani K.

Adv Exp Med Biol. 2017;977:199-204. doi: 10.1007/978-3-319-55231-6_27.


Molecular properties of a DTD channelrhodopsin from Guillardia theta.

Yamauchi Y, Konno M, Ito S, Tsunoda SP, Inoue K, Kandori H.

Biophys Physicobiol. 2017 May 20;14:57-66. doi: 10.2142/biophysico.14.0_57. eCollection 2017.


Micro-RNA-130a-3p Regulates Gemcitabine Resistance via PPARG in Cholangiocarcinoma.

Asukai K, Kawamoto K, Eguchi H, Konno M, Asai A, Iwagami Y, Yamada D, Asaoka T, Noda T, Wada H, Gotoh K, Nishida N, Satoh T, Doki Y, Mori M, Ishii H.

Ann Surg Oncol. 2017 Aug;24(8):2344-2352. doi: 10.1245/s10434-017-5871-x. Epub 2017 May 30.


A Case of Adult Metastatic Rhabdomyosarcoma of the Prostate Cured by Long-Term Chemotherapy with Local Radiation.

Konno M, Mitsuzuka K, Yamada S, Yamashita S, Kaiho Y, Ito A, Watanabe M, Arai Y.

Urol Int. 2019;102(1):118-121. doi: 10.1159/000473861. Epub 2017 Apr 21.


Loss of tumour-specific ATM protein expression is an independent prognostic factor in early resected NSCLC.

Petersen LF, Klimowicz AC, Otsuka S, Elegbede AA, Petrillo SK, Williamson T, Williamson CT, Konno M, Lees-Miller SP, Hao D, Morris D, Magliocco AM, Bebb DG.

Oncotarget. 2017 Jun 13;8(24):38326-38336. doi: 10.18632/oncotarget.16215.

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