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Items: 1 to 50 of 254

1.

Cell Type Purification by Single-Cell Transcriptome-Trained Sorting.

Baron CS, Barve A, Muraro MJ, van der Linden R, Dharmadhikari G, Lyubimova A, de Koning EJP, van Oudenaarden A.

Cell. 2019 Oct 3;179(2):527-542.e19. doi: 10.1016/j.cell.2019.08.006.

2.

YtrASa, a GntR-Family Transcription Factor, Represses Two Genetic Loci Encoding Membrane Proteins in Sulfolobus acidocaldarius.

Lemmens L, Tilleman L, De Koning E, Valegård K, Lindås AC, Van Nieuwerburgh F, Maes D, Peeters E.

Front Microbiol. 2019 Sep 10;10:2084. doi: 10.3389/fmicb.2019.02084. eCollection 2019.

3.

Genome-Wide Association Study on the Early Phase Insulin Response to a Liquid Mixed Meal: Results From the NEO Study.

Li-Gao R, Carlotti F, de Mutsert R, van Hylckama Vlieg A, de Koning EJP, Jukema JW, Rosendaal FR, Willems van Dijk K, Mook-Kanamori DO.

Diabetes. 2019 Sep 19. pii: db190378. doi: 10.2337/db19-0378. [Epub ahead of print]

PMID:
31537524
4.

Advances in β-cell replacement therapy for the treatment of type 1 diabetes.

Vantyghem MC, de Koning EJP, Pattou F, Rickels MR.

Lancet. 2019 Oct 5;394(10205):1274-1285. doi: 10.1016/S0140-6736(19)31334-0. Epub 2019 Sep 15. Review.

PMID:
31533905
5.

Individualised targets for insulin initiation in type 2 diabetes mellitus-the influence of physician and practice: a cross-sectional study in eight European countries.

Boels AM, Koning E, Vos RC, Khunti K, Rutten GE.

BMJ Open. 2019 Aug 26;9(8):e032040. doi: 10.1136/bmjopen-2019-032040.

6.

SUGAR-DIP trial: oral medication strategy versus insulin for diabetes in pregnancy, study protocol for a multicentre, open-label, non-inferiority, randomised controlled trial.

de Wit L, Rademaker D, Voormolen DN, Akerboom BMC, Kiewiet-Kemper RM, Soeters MR, Verwij-Didden MAL, Assouiki F, Schippers DH, Vermeulen MAR, Kuppens SMI, Oosterwerff MM, Zwart JJ, Diekman MJM, Vogelvang TE, Gallas PRJ, Galjaard S, Visser W, Horree N, Klooker TK, Laan R, Heijligenberg R, Huisjes AJM, van Bemmel T, van Meir CA, van den Beld AW, Hermes W, Vidarsdottir S, Veldhuis-Vlug AG, Dullemond RC, Jansen HJ, Sueters M, de Koning EJP, van Laar JOEH, Wouters-van Poppel P, Sanson-van Praag ME, van den Akker ES, Brouwer CB, Hermsen BB, Potter van Loon BJ, van der Heijden OWH, de Galan BE, van Leeuwen M, Wijbenga JAM, de Boer K, van Bon AC, van der Made FW, Eskes SA, Zandstra M, van Houtum WH, Braams-Lisman BAM, Daemen-Gubbels CRGM, Wouters MGAJ, IJzerman RG, Mensing van Charante NA, Zwertbroek R, Bosmans JE, Evers IM, Mol BW, de Valk HW, Groenendaal F, Naaktgeboren CA, Painter RC, deVries JH, Franx A, van Rijn BB.

BMJ Open. 2019 Aug 18;9(8):e029808. doi: 10.1136/bmjopen-2019-029808.

7.

Heterogeneity of human pancreatic islet isolation around Europe: results of a survey study.

Nano R, Kerr-Conte JA, Scholz H, Engelse M, Karlsson M, Saudek F, Bosco D, Antonioli B, Bertuzzi F, Johnson PRV, Ludwing B, Ling Z, De Paep DL, Keymeulen B, Pattou F, Berney T, Korsgren O, de Koning E, Piemonti L.

Transplantation. 2019 Jul 17. doi: 10.1097/TP.0000000000002777. [Epub ahead of print]

PMID:
31365472
8.

Vitamin D supplementation for the prevention of depression and poor physical function in older persons: the D-Vitaal study, a randomized clinical trial.

de Koning EJ, Lips P, Penninx BW, Elders PJ, Heijboer AC, den Heijer M, Bet PM, van Marwijk HW, van Schoor NM.

Am J Clin Nutr. 2019 Jul 24. pii: nqz141. doi: 10.1093/ajcn/nqz141. [Epub ahead of print]

PMID:
31340012
9.

Association between person and disease related factors and the planned diabetes care in people who receive person-centered type 2 diabetes care: An implementation study.

van Vugt HA, de Koning EJP, Rutten GEHM.

PLoS One. 2019 Jul 24;14(7):e0219702. doi: 10.1371/journal.pone.0219702. eCollection 2019.

10.

Glomerular Function and Structural Integrity Depend on Hyaluronan Synthesis by Glomerular Endothelium.

van den Berg BM, Wang G, Boels MGS, Avramut MC, Jansen E, Sol WMPJ, Lebrin F, Jan van Zonneveld A, de Koning EJP, Vink H, Gröne HJ, Carmeliet P, van der Vlag J, Rabelink TJ.

J Am Soc Nephrol. 2019 Oct;30(10):1886-1897. doi: 10.1681/ASN.2019020192. Epub 2019 Jul 15.

PMID:
31308073
11.

Factors that influence the intended intensity of diabetes care in a person-centred setting.

van Vugt HA, Heijmans MJWM, de Koning EJP, Rutten GEHM.

Diabet Med. 2019 Jul 6. doi: 10.1111/dme.14072. [Epub ahead of print]

PMID:
31278874
12.

Human pancreatic islet three-dimensional chromatin architecture provides insights into the genetics of type 2 diabetes.

Miguel-Escalada I, Bonàs-Guarch S, Cebola I, Ponsa-Cobas J, Mendieta-Esteban J, Atla G, Javierre BM, Rolando DMY, Farabella I, Morgan CC, García-Hurtado J, Beucher A, Morán I, Pasquali L, Ramos-Rodríguez M, Appel EVR, Linneberg A, Gjesing AP, Witte DR, Pedersen O, Grarup N, Ravassard P, Torrents D, Mercader JM, Piemonti L, Berney T, de Koning EJP, Kerr-Conte J, Pattou F, Fedko IO, Groop L, Prokopenko I, Hansen T, Marti-Renom MA, Fraser P, Ferrer J.

Nat Genet. 2019 Jul;51(7):1137-1148. doi: 10.1038/s41588-019-0457-0. Epub 2019 Jun 28.

13.

A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas.

van Gurp L, Muraro MJ, Dielen T, Seneby L, Dharmadhikari G, Gradwohl G, van Oudenaarden A, de Koning EJP.

Development. 2019 Jun 24;146(12). pii: dev173716. doi: 10.1242/dev.173716.

PMID:
31160419
14.

Effect of 6-Month Vitamin D Supplementation on Plasma Matrix Gla Protein in Older Adults.

van Ballegooijen AJ, Beulens JWJ, Schurgers LJ, de Koning EJ, Lips P, van Schoor NM, Vervloet MG.

Nutrients. 2019 Jan 22;11(2). pii: E231. doi: 10.3390/nu11020231.

15.

In Vivo Silencing of MicroRNA-132 Reduces Blood Glucose and Improves Insulin Secretion.

Bijkerk R, Esguerra JLS, Ellenbroek JH, Au YW, Hanegraaf MAJ, de Koning EJ, Eliasson L, van Zonneveld AJ.

Nucleic Acid Ther. 2019 Apr;29(2):67-72. doi: 10.1089/nat.2018.0763. Epub 2019 Jan 23.

PMID:
30672723
16.

Patient activation in individuals with type 2 diabetes mellitus: associated factors and the role of insulin.

van Vugt HA, Boels AM, de Weerdt I, de Koning EJ, Rutten GE.

Patient Prefer Adherence. 2018 Dec 28;13:73-81. doi: 10.2147/PPA.S188391. eCollection 2019.

17.

Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets.

Hadavi E, Leijten J, Engelse M, de Koning E, Jonkheijm P, Karperien M, van Apeldoorn A.

Tissue Eng Part C Methods. 2019 Feb;25(2):71-81. doi: 10.1089/ten.TEC.2018.0336.

PMID:
30632461
18.

Within-person pain variability and physical activity in older adults with osteoarthritis from six European countries.

Timmermans EJ, de Koning EJ, van Schoor NM, van der Pas S, Denkinger MD, Dennison EM, Maggi S, Pedersen NL, Otero Á, Peter R, Cooper C, Siviero P, Castell MV, Herbolsheimer F, Edwards M, Limongi F, Deeg DJH, Schaap LA.

BMC Musculoskelet Disord. 2019 Jan 5;20(1):12. doi: 10.1186/s12891-018-2392-0.

19.

Bioluminescent reporter assay for monitoring ER stress in human beta cells.

Kracht MJL, de Koning EJP, Hoeben RC, Roep BO, Zaldumbide A.

Sci Rep. 2018 Dec 10;8(1):17738. doi: 10.1038/s41598-018-36142-4.

20.

Associated auto-immune disease in type 1 diabetes patients: a systematic review and meta-analysis.

Nederstigt C, Uitbeijerse BS, Janssen LGM, Corssmit EPM, de Koning EJP, Dekkers OM.

Eur J Endocrinol. 2019 Feb 1;180(2):135-144. doi: 10.1530/EJE-18-0515.

PMID:
30508413
21.

Hypothermic Oxygenated Machine Perfusion of the Human Donor Pancreas.

Leemkuil M, Lier G, Engelse MA, Ploeg RJ, de Koning EJP, 't Hart NA, Krikke C, Leuvenink HGD.

Transplant Direct. 2018 Sep 7;4(10):e388. doi: 10.1097/TXD.0000000000000829. eCollection 2018 Oct.

22.

Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults

Elstgeest LEM, de Koning EJ, Brouwer IA, van Schoor NM, Penninx BWJH, Visser M.

Eur J Endocrinol. 2018 Oct 1;179(4):239-249. doi: 10.1530/EJE-18-0187.

PMID:
30299894
23.

Artificial Pancreas or Novel Beta-Cell Replacement Therapies: a Race for Optimal Glycemic Control?

Nijhoff MF, de Koning EJP.

Curr Diab Rep. 2018 Sep 24;18(11):110. doi: 10.1007/s11892-018-1073-6. Review.

24.

RVCL-S and CADASIL display distinct impaired vascular function.

de Boer I, Stam AH, Buntinx L, Zielman R, van der Steen I, van den Maagdenberg AMJM, de Koning EJP, Ferrari MD, de Hoon JN, Terwindt GM.

Neurology. 2018 Sep 4;91(10):e956-e963. doi: 10.1212/WNL.0000000000006119. Epub 2018 Aug 3.

PMID:
30076273
25.

Change in serum 25-hydroxyvitamin D and parallel change in depressive symptoms in Dutch older adults.

Elstgeest LEM, de Koning EJ, Brouwer IA, van Schoor NM, Penninx BWJH, Visser M.

Eur J Endocrinol. 2018 Jul 27. pii: EJE-18-0187. doi: 10.1530/EJE-18-0187. [Epub ahead of print]

PMID:
30054306
26.

Vegf-A mRNA transfection as a novel approach to improve mouse and human islet graft revascularisation.

Staels W, Verdonck Y, Heremans Y, Leuckx G, De Groef S, Heirman C, de Koning E, Gysemans C, Thielemans K, Baeyens L, Heimberg H, De Leu N.

Diabetologia. 2018 Aug;61(8):1804-1810. doi: 10.1007/s00125-018-4646-7. Epub 2018 May 22.

PMID:
29789879
27.

Vitamin D Status and Depressive Symptoms in Older Adults: A Role for Physical Functioning?

de Koning EJ, Elstgeest LEM, Comijs HC, Lips P, Rijnhart JJM, van Marwijk HWJ, Beekman ATF, Visser M, Penninx BWJH, van Schoor NM.

Am J Geriatr Psychiatry. 2018 Nov;26(11):1131-1143. doi: 10.1016/j.jagp.2018.03.004. Epub 2018 Mar 12.

PMID:
29628322
28.

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential.

Loomans CJM, Williams Giuliani N, Balak J, Ringnalda F, van Gurp L, Huch M, Boj SF, Sato T, Kester L, de Sousa Lopes SMC, Roost MS, Bonner-Weir S, Engelse MA, Rabelink TJ, Heimberg H, Vries RGJ, van Oudenaarden A, Carlotti F, Clevers H, de Koning EJP.

Stem Cell Reports. 2018 Mar 13;10(3):712-724. doi: 10.1016/j.stemcr.2018.02.005.

29.

Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transplantation. 2018 Sep;102(9):1479-1486. doi: 10.1097/TP.0000000000002158. Review.

30.

Defining outcomes for beta cell replacement therapy: a work in progress.

Piemonti L, de Koning EJP, Berney T, Odorico JS, Markmann JF, Stock PG, Rickels MR.

Diabetologia. 2018 Jun;61(6):1273-1276. doi: 10.1007/s00125-018-4588-0. Epub 2018 Mar 6.

31.

Within-Person Pain Variability and Mental Health in Older Adults With Osteoarthritis: An Analysis Across 6 European Cohorts.

de Koning EJ, Timmermans EJ, van Schoor NM, Stubbs B, van den Kommer TN, Dennison EM, Limongi F, Castell MV, Edwards MH, Queipo R, Cooper C, Siviero P, van der Pas S, Pedersen NL, Sánchez-Martínez M, Deeg DJH, Denkinger MD; EPOSA Group.

J Pain. 2018 Jun;19(6):690-698. doi: 10.1016/j.jpain.2018.02.006. Epub 2018 Mar 2.

32.

[Transplantation of islets of Langerhans: procedure, indications and challenges].

Nijhoff MF, Huurman VAL, Dubbeld J, van Erkel AR, Rabelink TA, Engelse MA, de Koning EJP.

Ned Tijdschr Geneeskd. 2018;162:D2201. Dutch.

PMID:
29493470
33.

Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transpl Int. 2018 Apr;31(4):343-352. doi: 10.1111/tri.13138. Review.

34.

Implementation of a Structured Diabetes Consultation Model to Facilitate a Person-Centered Approach: Results From a Nationwide Dutch Study.

Rutten GEHM, van Vugt HA, de Weerdt I, de Koning E.

Diabetes Care. 2018 Apr;41(4):688-695. doi: 10.2337/dc17-1194. Epub 2018 Jan 23.

PMID:
29363538
35.

Associations of Abdominal Subcutaneous and Visceral Fat with Insulin Resistance and Secretion Differ Between Men and Women: The Netherlands Epidemiology of Obesity Study.

de Mutsert R, Gast K, Widya R, de Koning E, Jazet I, Lamb H, le Cessie S, de Roos A, Smit J, Rosendaal F, den Heijer M.

Metab Syndr Relat Disord. 2018 Feb;16(1):54-63. doi: 10.1089/met.2017.0128. Epub 2018 Jan 17.

PMID:
29338526
36.

MiR-184 expression is regulated by AMPK in pancreatic islets.

Martinez-Sanchez A, Nguyen-Tu MS, Cebola I, Yavari A, Marchetti P, Piemonti L, de Koning E, Shapiro AMJ, Johnson P, Sakamoto K, Smith DM, Leclerc I, Ashrafian H, Ferrer J, Rutter GA.

FASEB J. 2018 May;32(5):2587-2600. doi: 10.1096/fj.201701100R. Epub 2018 Jan 8.

37.

Islet cells share promoter hypomethylation independently of expression, but exhibit cell-type-specific methylation in enhancers.

Neiman D, Moss J, Hecht M, Magenheim J, Piyanzin S, Shapiro AMJ, de Koning EJP, Razin A, Cedar H, Shemer R, Dor Y.

Proc Natl Acad Sci U S A. 2017 Dec 19;114(51):13525-13530. doi: 10.1073/pnas.1713736114. Epub 2017 Dec 4.

38.

Interrelationship of the rs7903146 TCF7L2 gene variant with measures of glucose metabolism and adiposity: The NEO study.

Noordam R, Zwetsloot CPA, de Mutsert R, Mook-Kanamori DO, Lamb HJ, de Roos A, de Koning EJP, Rosendaal FR, Willems van Dijk K, van Heemst D.

Nutr Metab Cardiovasc Dis. 2018 Feb;28(2):150-157. doi: 10.1016/j.numecd.2017.10.012. Epub 2017 Oct 18.

PMID:
29174029
39.

Islet alloautotransplantation: Allogeneic pancreas transplantation followed by transplant pancreatectomy and islet transplantation.

Nijhoff MF, Dubbeld J, van Erkel AR, van der Boog PJM, Rabelink TJ, Engelse MA, de Koning EJP.

Am J Transplant. 2018 Apr;18(4):1016-1019. doi: 10.1111/ajt.14593. Epub 2017 Dec 18.

40.

Layered PEGDA hydrogel for islet of Langerhans encapsulation and improvement of vascularization.

Marchioli G, Zellner L, Oliveira C, Engelse M, Koning E, Mano J, Karperien, Apeldoorn AV, Moroni L.

J Mater Sci Mater Med. 2017 Nov 18;28(12):195. doi: 10.1007/s10856-017-6004-6.

41.

Impaired contrast sensitivity at low spatial frequency in cannabis users with early onset.

Lalanne L, Ferrand-Devouge E, Kirchherr S, Rauch L, Koning E, Speeg C, Laprevote V, Giersch A.

Eur Neuropsychopharmacol. 2017 Dec;27(12):1289-1297. doi: 10.1016/j.euroneuro.2017.09.006. Epub 2017 Oct 12.

PMID:
29031837
42.

DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells.

Roost MS, Slieker RC, Bialecka M, van Iperen L, Gomes Fernandes MM, He N, Suchiman HED, Szuhai K, Carlotti F, de Koning EJP, Mummery CL, Heijmans BT, Chuva de Sousa Lopes SM.

Nat Commun. 2017 Oct 13;8(1):908. doi: 10.1038/s41467-017-01077-3.

43.

Pancreas Transplantation With Grafts From Donors Deceased After Circulatory Death: 5 Years Single-Center Experience.

Kopp WH, Lam HD, Schaapherder AFM, Huurman VAL, van der Boog PJM, de Koning EJP, de Fijter JW, Baranski AG, Braat AE.

Transplantation. 2018 Feb;102(2):333-339. doi: 10.1097/TP.0000000000001940.

PMID:
28885491
44.

Pancreatic islet macroencapsulation using microwell porous membranes.

Skrzypek K, Groot Nibbelink M, van Lente J, Buitinga M, Engelse MA, de Koning EJP, Karperien M, van Apeldoorn A, Stamatialis D.

Sci Rep. 2017 Aug 23;7(1):9186. doi: 10.1038/s41598-017-09647-7.

45.

Magnetic resonance imaging may predict deep remission in patients with perianal fistulizing Crohn's disease.

Thomassin L, Armengol-Debeir L, Charpentier C, Bridoux V, Koning E, Savoye G, Savoye-Collet C.

World J Gastroenterol. 2017 Jun 21;23(23):4285-4292. doi: 10.3748/wjg.v23.i23.4285.

46.

The relationship between serum 25(OH)D levels and anxiety symptoms in older persons: Results from the Longitudinal Aging Study Amsterdam.

de Koning EJ, Verweij L, Lips P, Beekman ATF, Comijs HC, van Schoor NM.

J Psychosom Res. 2017 Jun;97:90-95. doi: 10.1016/j.jpsychores.2017.04.005. Epub 2017 Apr 20.

PMID:
28606505
47.

In-Culture Cross-Linking of Bacterial Cells Reveals Large-Scale Dynamic Protein-Protein Interactions at the Peptide Level.

de Jong L, de Koning EA, Roseboom W, Buncherd H, Wanner MJ, Dapic I, Jansen PJ, van Maarseveen JH, Corthals GL, Lewis PJ, Hamoen LW, de Koster CG.

J Proteome Res. 2017 Jul 7;16(7):2457-2471. doi: 10.1021/acs.jproteome.7b00068. Epub 2017 May 26.

48.

Association of fasting triglyceride concentration and postprandial triglyceride response with the carotid intima-media thickness in the middle aged: The Netherlands Epidemiology of Obesity study.

Christen T, de Mutsert R, Gast KB, Rensen PCN, de Koning E, Rosendaal FR, Trompet S, Jukema JW.

J Clin Lipidol. 2017 Mar - Apr;11(2):377-385.e1. doi: 10.1016/j.jacl.2016.12.016. Epub 2017 Jan 23.

PMID:
28502494
49.

Micro-fabricated scaffolds lead to efficient remission of diabetes in mice.

Buitinga M, Assen F, Hanegraaf M, Wieringa P, Hilderink J, Moroni L, Truckenmüller R, van Blitterswijk C, Römer GW, Carlotti F, de Koning E, Karperien M, van Apeldoorn A.

Biomaterials. 2017 Aug;135:10-22. doi: 10.1016/j.biomaterials.2017.03.031. Epub 2017 Mar 27.

PMID:
28478326
50.

Pancreatic α-cell mass in obesity.

Ellenbroek JH, Töns HAM, Hanegraaf MAJ, Rabelink TJ, Engelse MA, Carlotti F, de Koning EJP.

Diabetes Obes Metab. 2017 Dec;19(12):1810-1813. doi: 10.1111/dom.12997. Epub 2017 Jul 13.

PMID:
28474364

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