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Items: 1 to 50 of 127

1.

Single-molecule FRET reveals proofreading complexes in the large fragment of Bacillus stearothermophilus DNA polymerase I.

Christian TV, Konigsberg WH.

AIMS Biophys. 2018;5(2):144-154. doi: 10.3934/biophy.2018.2.144. Epub 2018 May 10.

2.

The effect of different divalent cations on the kinetics and fidelity of Bacillus stearothermophilus DNA polymerase.

Vashishtha AK, Konigsberg WH.

AIMS Biophys. 2018;5(2):125-143. doi: 10.3934/biophy.2018.2.125. Epub 2018 Apr 25.

3.

Different Divalent Cations Alter the Kinetics and Fidelity of DNA Polymerases.

Vashishtha AK, Wang J, Konigsberg WH.

J Biol Chem. 2016 Sep 30;291(40):20869-20875. Epub 2016 Jul 26. Review.

4.

Effect of Different Divalent Cations on the Kinetics and Fidelity of RB69 DNA Polymerase.

Vashishtha AK, Konigsberg WH.

Biochemistry. 2016 May 10;55(18):2661-70. doi: 10.1021/acs.biochem.5b01350. Epub 2016 Apr 28.

5.

RB69 DNA polymerase structure, kinetics, and fidelity.

Xia S, Konigsberg WH.

Biochemistry. 2014 May 6;53(17):2752-67. doi: 10.1021/bi4014215. Epub 2014 Apr 23. Review.

6.

Mispairs with Watson-Crick base-pair geometry observed in ternary complexes of an RB69 DNA polymerase variant.

Xia S, Konigsberg WH.

Protein Sci. 2014 Apr;23(4):508-13. doi: 10.1002/pro.2434.

7.

Alteration in the cavity size adjacent to the active site of RB69 DNA polymerase changes its conformational dynamics.

Xia S, Wood M, Bradley MJ, De La Cruz EM, Konigsberg WH.

Nucleic Acids Res. 2013 Oct;41(19):9077-89. doi: 10.1093/nar/gkt674. Epub 2013 Aug 5.

8.

DNA mismatch synthesis complexes provide insights into base selectivity of a B family DNA polymerase.

Xia S, Wang J, Konigsberg WH.

J Am Chem Soc. 2013 Jan 9;135(1):193-202. doi: 10.1021/ja3079048. Epub 2012 Dec 21.

9.

Structural and mechanistic insights into guanylylation of RNA-splicing ligase RtcB joining RNA between 3'-terminal phosphate and 5'-OH.

Englert M, Xia S, Okada C, Nakamura A, Tanavde V, Yao M, Eom SH, Konigsberg WH, Söll D, Wang J.

Proc Natl Acad Sci U S A. 2012 Sep 18;109(38):15235-40. Epub 2012 Sep 4.

10.

Contribution of partial charge interactions and base stacking to the efficiency of primer extension at and beyond abasic sites in DNA.

Xia S, Vashishtha A, Bulkley D, Eom SH, Wang J, Konigsberg WH.

Biochemistry. 2012 Jun 19;51(24):4922-31. doi: 10.1021/bi300296q. Epub 2012 Jun 7.

11.
12.

Probing minor groove hydrogen bonding interactions between RB69 DNA polymerase and DNA.

Xia S, Christian TD, Wang J, Konigsberg WH.

Biochemistry. 2012 May 29;51(21):4343-53. doi: 10.1021/bi300416z. Epub 2012 May 17.

13.

Structural basis for differential insertion kinetics of dNMPs opposite a difluorotoluene nucleotide residue.

Xia S, Eom SH, Konigsberg WH, Wang J.

Biochemistry. 2012 Feb 21;51(7):1476-85. doi: 10.1021/bi2016487. Epub 2012 Feb 8.

14.

Bidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymerase.

Xia S, Eom SH, Konigsberg WH, Wang J.

Protein Sci. 2012 Mar;21(3):447-51. doi: 10.1002/pro.2026. Epub 2012 Jan 31.

15.

Structural insights into complete metal ion coordination from ternary complexes of B family RB69 DNA polymerase.

Xia S, Wang M, Blaha G, Konigsberg WH, Wang J.

Biochemistry. 2011 Oct 25;50(42):9114-24. doi: 10.1021/bi201260h. Epub 2011 Sep 29.

16.

Hydrogen-bonding capability of a templating difluorotoluene nucleotide residue in an RB69 DNA polymerase ternary complex.

Xia S, Konigsberg WH, Wang J.

J Am Chem Soc. 2011 Jul 6;133(26):10003-5. doi: 10.1021/ja2021735. Epub 2011 Jun 15.

17.

Insights into base selectivity from the 1.8 Å resolution structure of an RB69 DNA polymerase ternary complex.

Wang M, Xia S, Blaha G, Steitz TA, Konigsberg WH, Wang J.

Biochemistry. 2011 Feb 1;50(4):581-90. doi: 10.1021/bi101192f. Epub 2010 Dec 30.

18.

Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP and dGMP to be inserted opposite Guanidinohydantoin .

Beckman J, Wang M, Blaha G, Wang J, Konigsberg WH.

Biochemistry. 2010 Oct 5;49(39):8554-63. doi: 10.1021/bi100913v. Epub 2010 Sep 9.

19.

Substitution of Ala for Tyr567 in RB69 DNA polymerase allows dAMP to be inserted opposite 7,8-dihydro-8-oxoguanine .

Beckman J, Wang M, Blaha G, Wang J, Konigsberg WH.

Biochemistry. 2010 May 18;49(19):4116-25. doi: 10.1021/bi100102s.

20.

Single-molecule and ensemble fluorescence assays for a functionally important conformational change in T7 DNA polymerase.

Luo G, Wang M, Konigsberg WH, Xie XS.

Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12610-5. Epub 2007 Jul 18.

21.

Formation of tissue factor-factor VIIa-factor Xa complex promotes cellular signaling and migration of human breast cancer cells.

Jiang X, Bailly MA, Panetti TS, Cappello M, Konigsberg WH, Bromberg ME.

J Thromb Haemost. 2004 Jan;2(1):93-101.

22.

Dissecting the fidelity of bacteriophage RB69 DNA polymerase: site-specific modulation of fidelity by polymerase accessory proteins.

Bebenek A, Carver GT, Dressman HK, Kadyrov FA, Haseman JK, Petrov V, Konigsberg WH, Karam JD, Drake JW.

Genetics. 2002 Nov;162(3):1003-18.

23.

Role of protease-activated receptor 1 in tumor metastasis promoted by tissue factor.

Bromberg ME, Bailly MA, Konigsberg WH.

Thromb Haemost. 2001 Nov;86(5):1210-4.

PMID:
11816709
24.
25.

Interacting fidelity defects in the replicative DNA polymerase of bacteriophage RB69.

Bebenek A, Dressman HK, Carver GT, Ng S, Petrov V, Yang G, Konigsberg WH, Karam JD, Drake JW.

J Biol Chem. 2001 Mar 30;276(13):10387-97. Epub 2000 Dec 22.

26.

DNA polymerase of the T4-related bacteriophages.

Karam JD, Konigsberg WH.

Prog Nucleic Acid Res Mol Biol. 2000;64:65-96. Review.

PMID:
10697407
27.

Role of tissue factor in metastasis: functions of the cytoplasmic and extracellular domains of the molecule.

Bromberg ME, Sundaram R, Homer RJ, Garen A, Konigsberg WH.

Thromb Haemost. 1999 Jul;82(1):88-92.

PMID:
10456459
28.

Steady-state kinetic characterization of RB69 DNA polymerase mutants that affect dNTP incorporation.

Yang G, Lin T, Karam J, Konigsberg WH.

Biochemistry. 1999 Jun 22;38(25):8094-101.

PMID:
10387055
29.

Ancylostoma caninum anticoagulant peptide blocks metastasis in vivo and inhibits factor Xa binding to melanoma cells in vitro.

Donnelly KM, Bromberg ME, Milstone A, Madison McNiff JM, Terwilliger G, Konigsberg WH, Cappello M.

Thromb Haemost. 1998 May;79(5):1041-7.

PMID:
9609244
30.

Residues at the carboxy terminus of T4 DNA polymerase are important determinants for interaction with the polymerase accessory proteins.

Goodrich LD, Lin TC, Spicer EK, Jones C, Konigsberg WH.

Biochemistry. 1997 Aug 26;36(34):10474-81.

PMID:
9265627
31.

Crystal structure of a pol alpha family replication DNA polymerase from bacteriophage RB69.

Wang J, Sattar AK, Wang CC, Karam JD, Konigsberg WH, Steitz TA.

Cell. 1997 Jun 27;89(7):1087-99.

32.

Functional consequences and exonuclease kinetic parameters of point mutations in bacteriophage T4 DNA polymerase.

Abdus Sattar AK, Lin TC, Jones C, Konigsberg WH.

Biochemistry. 1996 Dec 24;35(51):16621-9.

PMID:
8987997
33.

Activation of factor X by factor VIIa complexed with human-mouse tissue factor chimeras requires human exon 3.

Fang CH, Lin TC, Guha A, Nemerson Y, Konigsberg WH.

Thromb Haemost. 1996 Sep;76(3):361-8.

PMID:
8883271
34.
35.

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor.

Banner DW, D'Arcy A, Chène C, Winkler FK, Guha A, Konigsberg WH, Nemerson Y, Kirchhofer D.

Nature. 1996 Mar 7;380(6569):41-6.

PMID:
8598903
36.

Tissue factor promotes melanoma metastasis by a pathway independent of blood coagulation.

Bromberg ME, Konigsberg WH, Madison JF, Pawashe A, Garen A.

Proc Natl Acad Sci U S A. 1995 Aug 29;92(18):8205-9.

37.

Activation of blood coagulation factor VIIa with cleaved tissue factor extracellular domain and crystallization of the active complex.

Kirchhofer D, Guha A, Nemerson Y, Konigsberg WH, Vilbois F, Chène C, Banner DW, D'Arcy A.

Proteins. 1995 Aug;22(4):419-25.

PMID:
7479715
38.

Crystal structure of a replication fork single-stranded DNA binding protein (T4 gp32) complexed to DNA.

Shamoo Y, Friedman AM, Parsons MR, Konigsberg WH, Steitz TA.

Nature. 1995 Jul 27;376(6538):362-6. Erratum in: Nature 1995 Aug 17;376(6541):616.

PMID:
7630406
39.

Limited proteolysis of DNA polymerases as probe of functional domains.

Konigsberg WH.

Methods Enzymol. 1995;262:331-46.

PMID:
8594359
40.
41.

Procoagulant activity in cancer cells is dependent on tissue factor expression.

Hu T, Bach RR, Horton R, Konigsberg WH, Todd MB.

Oncol Res. 1994;6(7):321-7.

PMID:
7865907
42.

Synthesis of tissue factor messenger RNA and procoagulant activity in breast cancer cells in response to serum stimulation.

Hu T, Bach RR, Horton R, Konigsberg WH, Todd MB.

Thromb Res. 1993 Oct 15;72(2):155-68.

PMID:
8303653
43.

Translational repression by the bacteriophage T4 gene 32 protein involves specific recognition of an RNA pseudoknot structure.

Shamoo Y, Tam A, Konigsberg WH, Williams KR.

J Mol Biol. 1993 Jul 5;232(1):89-104.

PMID:
8331672
44.

Tissue factor and its extracellular soluble domain: the relationship between intermolecular association with factor VIIa and enzymatic activity of the complex.

Waxman E, Ross JB, Laue TM, Guha A, Thiruvikraman SV, Lin TC, Konigsberg WH, Nemerson Y.

Biochemistry. 1992 Apr 28;31(16):3998-4003.

PMID:
1567850
45.

A retrovirus-like zinc domain is essential for translational repression of bacteriophage T4 gene 32.

Shamoo Y, Webster KR, Williams KR, Konigsberg WH.

J Biol Chem. 1991 May 5;266(13):7967-70.

46.

DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.

Reha-Krantz LJ, Stocki S, Nonay RL, Dimayuga E, Goodrich LD, Konigsberg WH, Spicer EK.

Proc Natl Acad Sci U S A. 1991 Mar 15;88(6):2417-21.

47.

Identification of amino acid residues at interface of protein-nucleic acid complexes by photochemical cross-linking.

Williams KR, Konigsberg WH.

Methods Enzymol. 1991;208:516-39. No abstract available.

PMID:
1779846
48.

Photoaffinity labeling of the Klenow fragment with 8-azido-dATP.

Rush J, Konigsberg WH.

J Biol Chem. 1990 Mar 25;265(9):4821-7.

49.

Tissue factor gene expression in acute myeloblastic leukemia.

Bauer KA, Conway EM, Bach R, Konigsberg WH, Griffin JD, Demetri G.

Thromb Res. 1989 Nov 1;56(3):425-30.

PMID:
2617479
50.

Site-specific mutagenesis of T4 gene 32: the role of tyrosine residues in protein-nucleic acid interactions.

Shamoo Y, Ghosaini LR, Keating KM, Williams KR, Sturtevant JM, Konigsberg WH.

Biochemistry. 1989 Sep 5;28(18):7409-17.

PMID:
2684276

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