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Items: 27

1.

USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7.

Sapmaz A, Berlin I, Bos E, Wijdeven RH, Janssen H, Konietzny R, Akkermans JJ, Erson-Bensan AE, Koning RI, Kessler BM, Neefjes J, Ovaa H.

Nat Commun. 2019 Mar 29;10(1):1454. doi: 10.1038/s41467-019-09437-x.

2.

Deacetylation Inhibition Reverses PABPN1-Dependent Muscle Wasting.

Olie CS, Riaz M, Konietzny R, Charles PD, Pinto-Fernandez A, Kiełbasa SM, Aartsma-Rus A, Goeman JJ, Kessler BM, Raz V.

iScience. 2019 Feb 22;12:318-332. doi: 10.1016/j.isci.2019.01.024. Epub 2019 Jan 22.

3.

Human Platelet Protein Ubiquitylation and Changes following GPVI Activation.

Unsworth AJ, Bombik I, Pinto-Fernandez A, McGouran JF, Konietzny R, Zahedi RP, Watson SP, Kessler BM, Pears CJ.

Thromb Haemost. 2019 Jan;119(1):104-116. doi: 10.1055/s-0038-1676344. Epub 2018 Dec 31.

4.

An Activity-Based Probe Targeting Non-Catalytic, Highly Conserved Amino Acid Residues within Bromodomains.

D'Ascenzio M, Pugh KM, Konietzny R, Berridge G, Tallant C, Hashem S, Monteiro O, Thomas JR, Schirle M, Knapp S, Marsden B, Fedorov O, Bountra C, Kessler BM, Brennan PE.

Angew Chem Int Ed Engl. 2019 Jan 21;58(4):1007-1012. doi: 10.1002/anie.201807825. Epub 2018 Dec 27.

5.

The deubiquitylating enzyme UCHL3 regulates Ku80 retention at sites of DNA damage.

Nishi R, Wijnhoven PWG, Kimura Y, Matsui M, Konietzny R, Wu Q, Nakamura K, Blundell TL, Kessler BM.

Sci Rep. 2018 Dec 17;8(1):17891. doi: 10.1038/s41598-018-36235-0.

6.

Colorectal cancer liver metastatic growth depends on PAD4-driven citrullination of the extracellular matrix.

Yuzhalin AE, Gordon-Weeks AN, Tognoli ML, Jones K, Markelc B, Konietzny R, Fischer R, Muth A, O'Neill E, Thompson PR, Venables PJ, Kessler BM, Lim SY, Muschel RJ.

Nat Commun. 2018 Nov 14;9(1):4783. doi: 10.1038/s41467-018-07306-7.

7.

Quantitative Proteomics Identification of Seminal Fluid Proteins in Male Drosophila melanogaster.

Sepil I, Hopkins BR, Dean R, Thézénas ML, Charles PD, Konietzny R, Fischer R, Kessler BM, Wigby S.

Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S46-S58. doi: 10.1074/mcp.RA118.000831. Epub 2018 Oct 4.

8.

A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.

Zhang T, Wei G, Millard CJ, Fischer R, Konietzny R, Kessler BM, Schwabe JWR, Brockdorff N.

Nat Commun. 2018 Sep 18;9(1):3798. doi: 10.1038/s41467-018-06235-9.

9.

Publisher Correction: The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Leśniak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ.

Nat Chem Biol. 2018 Oct;14(10):988. doi: 10.1038/s41589-018-0104-6.

PMID:
29950663
10.

The Jumonji-C oxygenase JMJD7 catalyzes (3S)-lysyl hydroxylation of TRAFAC GTPases.

Markolovic S, Zhuang Q, Wilkins SE, Eaton CD, Abboud MI, Katz MJ, McNeil HE, Leśniak RK, Hall C, Struwe WB, Konietzny R, Davis S, Yang M, Ge W, Benesch JLP, Kessler BM, Ratcliffe PJ, Cockman ME, Fischer R, Wappner P, Chowdhury R, Coleman ML, Schofield CJ.

Nat Chem Biol. 2018 Jul;14(7):688-695. doi: 10.1038/s41589-018-0071-y. Epub 2018 Jun 18. Erratum in: Nat Chem Biol. 2018 Jun 27;:.

11.

FBXL19 recruits CDK-Mediator to CpG islands of developmental genes priming them for activation during lineage commitment.

Dimitrova E, Kondo T, Feldmann A, Nakayama M, Koseki Y, Konietzny R, Kessler BM, Koseki H, Klose RJ.

Elife. 2018 May 29;7. pii: e37084. doi: 10.7554/eLife.37084.

12.

Discovery of a Highly Selective Cell-Active Inhibitor of the Histone Lysine Demethylases KDM2/7.

Gerken PA, Wolstenhulme JR, Tumber A, Hatch SB, Zhang Y, Müller S, Chandler SA, Mair B, Li F, Nijman SMB, Konietzny R, Szommer T, Yapp C, Fedorov O, Benesch JLP, Vedadi M, Kessler BM, Kawamura A, Brennan PE, Smith MD.

Angew Chem Int Ed Engl. 2017 Dec 4;56(49):15555-15559. doi: 10.1002/anie.201706788. Epub 2017 Nov 7.

13.

Linker Histone H1.2 Directs Genome-wide Chromatin Association of the Retinoblastoma Tumor Suppressor Protein and Facilitates Its Function.

Munro S, Hookway ES, Floderer M, Carr SM, Konietzny R, Kessler BM, Oppermann U, La Thangue NB.

Cell Rep. 2017 Jun 13;19(11):2193-2201. doi: 10.1016/j.celrep.2017.05.053.

14.

E3 Ligase cIAP2 Mediates Downregulation of MRE11 and Radiosensitization in Response to HDAC Inhibition in Bladder Cancer.

Nicholson J, Jevons SJ, Groselj B, Ellermann S, Konietzny R, Kerr M, Kessler BM, Kiltie AE.

Cancer Res. 2017 Jun 1;77(11):3027-3039. doi: 10.1158/0008-5472.CAN-16-3232. Epub 2017 Mar 31.

15.

miR-193a-3p interaction with HMGB1 downregulates human endothelial cell proliferation and migration.

Khoo CP, Roubelakis MG, Schrader JB, Tsaknakis G, Konietzny R, Kessler B, Harris AL, Watt SM.

Sci Rep. 2017 Mar 9;7:44137. doi: 10.1038/srep44137.

16.

Proteomic changes in response to crystal formation in Drosophila Malpighian tubules.

Chung VY, Konietzny R, Charles P, Kessler B, Fischer R, Turney BW.

Fly (Austin). 2016 Apr 2;10(2):91-100. doi: 10.1080/19336934.2016.1171947. Epub 2016 Apr 11.

17.

Structure of the Human Protein Kinase ZAK in Complex with Vemurafenib.

Mathea S, Abdul Azeez KR, Salah E, Tallant C, Wolfreys F, Konietzny R, Fischer R, Lou HJ, Brennan PE, Schnapp G, Pautsch A, Kessler BM, Turk BE, Knapp S.

ACS Chem Biol. 2016 Jun 17;11(6):1595-602. doi: 10.1021/acschembio.6b00043. Epub 2016 Mar 31.

18.

USP4 Auto-Deubiquitylation Promotes Homologous Recombination.

Wijnhoven P, Konietzny R, Blackford AN, Travers J, Kessler BM, Nishi R, Jackson SP.

Mol Cell. 2015 Nov 5;60(3):362-73. doi: 10.1016/j.molcel.2015.09.019. Epub 2015 Oct 8.

19.

Expanding the yeast protein arginine methylome.

Plank M, Fischer R, Geoghegan V, Charles PD, Konietzny R, Acuto O, Pears C, Schofield CJ, Kessler BM.

Proteomics. 2015 Sep;15(18):3232-43. doi: 10.1002/pmic.201500032. Epub 2015 Jul 2.

PMID:
26046779
20.

Detection of BK virus in urine from renal transplant subjects by mass spectrometry.

Konietzny R, Fischer R, Ternette N, Wright CA, Turney BW, Chakera A, Hughes D, Kessler BM, Pugh CW.

Clin Proteomics. 2012 Apr 26;9(1):4.

21.

Arginine methylation controls growth regulation by E2F-1.

Cho EC, Zheng S, Munro S, Liu G, Carr SM, Moehlenbrink J, Lu YC, Stimson L, Khan O, Konietzny R, McGouran J, Coutts AS, Kessler B, Kerr DJ, Thangue NB.

EMBO J. 2012 Apr 4;31(7):1785-97. doi: 10.1038/emboj.2012.17. Epub 2012 Feb 10.

22.

Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes.

Altun M, Kramer HB, Willems LI, McDermott JL, Leach CA, Goldenberg SJ, Kumar KG, Konietzny R, Fischer R, Kogan E, Mackeen MM, McGouran J, Khoronenkova SV, Parsons JL, Dianov GL, Nicholson B, Kessler BM.

Chem Biol. 2011 Nov 23;18(11):1401-12. doi: 10.1016/j.chembiol.2011.08.018.

23.

Oxygen-regulated expression of the erythropoietin gene in the human renal cell line REPC.

Frede S, Freitag P, Geuting L, Konietzny R, Fandrey J.

Blood. 2011 May 5;117(18):4905-14. doi: 10.1182/blood-2010-07-298083. Epub 2011 Mar 15. Retraction in: Blood. 2014 May 22;123(21):3365.

PMID:
21406725
24.

Functionalized copolyimide membranes for the separation of gaseous and liquid mixtures.

Schmeling N, Konietzny R, Sieffert D, Rölling P, Staudt C.

Beilstein J Org Chem. 2010 Aug 12;6:789-800. doi: 10.3762/bjoc.6.86.

25.

Nanoscopy of the cellular response to hypoxia by means of fluorescence resonance energy transfer (FRET) and new FRET software.

Wotzlaw C, Gneuss S, Konietzny R, Fandrey J.

PMC Biophys. 2010 Mar 5;3(1):5. doi: 10.1186/1757-5036-3-5.

26.

Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.

Konietzny R, König A, Wotzlaw C, Bernadini A, Berchner-Pfannschmidt U, Fandrey J.

Ann N Y Acad Sci. 2009 Oct;1177:74-81. doi: 10.1111/j.1749-6632.2009.05029.x.

PMID:
19845609
27.

Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation.

Brandt S, Blissenbach M, Grewe B, Konietzny R, Grunwald T, Uberla K.

PLoS Pathog. 2007 Apr;3(4):e54.

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