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Items: 9


d-chiro-Inositol Ribophostin: A Highly Potent Agonist of d-myo-Inositol 1,4,5-Trisphosphate Receptors: Synthesis and Biological Activities.

Mills SJ, Rossi AM, Konieczny V, Bakowski D, Taylor CW, Potter BVL.

J Med Chem. 2020 Mar 26;63(6):3238-3251. doi: 10.1021/acs.jmedchem.9b01986. Epub 2020 Mar 10.


A synthetic diphosphoinositol phosphate analogue of inositol trisphosphate.

Riley AM, Unterlass J, Konieczny V, Taylor CW, Helleday T, Potter BVL.

Medchemcomm. 2018 Jul 1;9(7):1105-1113. doi: 10.1039/C8MD00149A. Epub 2018 Jun 4.


A Method for the Acute and Rapid Degradation of Endogenous Proteins.

Clift D, McEwan WA, Labzin LI, Konieczny V, Mogessie B, James LC, Schuh M.

Cell. 2017 Dec 14;171(7):1692-1706.e18. doi: 10.1016/j.cell.2017.10.033. Epub 2017 Nov 16.


Cyclic AMP Recruits a Discrete Intracellular Ca2+ Store by Unmasking Hypersensitive IP3 Receptors.

Konieczny V, Tovey SC, Mataragka S, Prole DL, Taylor CW.

Cell Rep. 2017 Jan 17;18(3):711-722. doi: 10.1016/j.celrep.2016.12.058.


Mutant IP3 receptors attenuate store-operated Ca2+ entry by destabilizing STIM-Orai interactions in Drosophila neurons.

Chakraborty S, Deb BK, Chorna T, Konieczny V, Taylor CW, Hasan G.

J Cell Sci. 2016 Oct 15;129(20):3903-3910. Epub 2016 Sep 2.


IP3 receptors: Take four IP3 to open.

Taylor CW, Konieczny V.

Sci Signal. 2016 Apr 5;9(422):pe1. doi: 10.1126/scisignal.aaf6029.


Synthesis of inositol phosphate-based competitive antagonists of inositol 1,4,5-trisphosphate receptors.

Konieczny V, Stefanakis JG, Sitsanidis ED, Ioannidou NA, Papadopoulos NV, Fylaktakidou KC, Taylor CW, Koumbis AE.

Org Biomol Chem. 2016 Feb 28;14(8):2504-14. doi: 10.1039/c5ob02623g.


Triazolophostins: a library of novel and potent agonists of IP3 receptors.

Vibhute AM, Konieczny V, Taylor CW, Sureshan KM.

Org Biomol Chem. 2015 Jun 28;13(24):6698-710. doi: 10.1039/c5ob00440c.


Spatial organization of intracellular Ca2+ signals.

Konieczny V, Keebler MV, Taylor CW.

Semin Cell Dev Biol. 2012 Apr;23(2):172-80. doi: 10.1016/j.semcdb.2011.09.006. Epub 2011 Sep 13. Review.

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