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UVB drives different stages of epigenome alterations during progression of skin cancer.

Yang Y, Wu R, Sargsyan D, Yin R, Kuo HC, Yang I, Wang L, Cheng D, Wang C, Li S, Hudlikar R, Lu Y, Kong AN.

Cancer Lett. 2019 Feb 13. pii: S0304-3835(19)30082-5. doi: 10.1016/j.canlet.2019.02.010. [Epub ahead of print]


Screening of endogenous strong promoters for enhanced production of medium-chain-length polyhydroxyalkanoates in Pseudomonas mendocina NK-01.

Zhao F, Liu X, Kong A, Zhao Y, Fan X, Ma T, Gao W, Wang S, Yang C.

Sci Rep. 2019 Feb 12;9(1):1798. doi: 10.1038/s41598-019-39321-z.


Pre-diagnostic carbohydrate intake and treatment failure after radical prostatectomy for early-stage prostate cancer.

Kim K, Kong A, Flanigan RC, Quek ML, Hollowell CMP, Vidal PP, Branch J, Dean LA, Macias V, Kajadacsy-Balla AA, Fitzgibbon ML, Cintron D, Liu L, Freeman VL.

Cancer Causes Control. 2019 Feb 7. doi: 10.1007/s10552-019-1134-4. [Epub ahead of print]


Gender differences in the associations between insomnia and glycemic control in patients with type 2 diabetes: a cross-sectional study.

Ding C, Zhang J, Lau ESH, Luk AOY, So WY, Ma RCW, Choi KC, Chan JCN, Wing YK, Kong APS.

Sleep. 2019 Feb 4. doi: 10.1093/sleep/zsz014. [Epub ahead of print]


Hsp74/14-3-3σ Complex Mediates Centrosome Amplification by High Glucose, Insulin and Palmitic Acid.

Lu YC, Wang P, Wu QG, Zhang RK, Kong A, Li YF, Lee SC.

Proteomics. 2019 Jan 28:e1800197. doi: 10.1002/pmic.201800197. [Epub ahead of print]


Overcoming acquired resistance to HSP90 inhibition by targeting JAK-STAT signalling in triple-negative breast cancer.

Mumin NH, Drobnitzky N, Patel A, Lourenco LM, Cahill FF, Jiang Y, Kong A, Ryan AJ.

BMC Cancer. 2019 Jan 24;19(1):102. doi: 10.1186/s12885-019-5295-z.


Excess Burden of Mental Illness and Hospitalization in Young-Onset Type 2 Diabetes: A Population-Based Cohort Study.

Ke C, Lau E, Shah BR, Stukel TA, Ma RC, So WY, Kong AP, Chow E, Clarke P, Goggins W, Chan JCN, Luk A.

Ann Intern Med. 2019 Jan 15. doi: 10.7326/M18-1900. [Epub ahead of print]


A Pilot Study of the Effect of an Educational Web Application on Asthma Control and Medication Adherence.

Weinstein AG, Singh A, Laurenceau JP, Skoner DP, Maiolo J, Sharara R, Ma K, Cheema T, Butler E, Kong A, Thakkar P, Gentile DA.

J Allergy Clin Immunol Pract. 2019 Jan 11. pii: S2213-2198(19)30049-2. doi: 10.1016/j.jaip.2018.12.024. [Epub ahead of print]


Bio-inspired chitosan-heme-vitamin B12-derived Fe-Co bimetallic-doped mesoporous carbons for efficiently electro-activating oxygen.

Ma Z, Xu L, Liu L, Wang L, Zhang X, Kong A.

Dalton Trans. 2019 Feb 12;48(7):2338-2344. doi: 10.1039/c8dt04279a.


Evidence for the approach to the diagnostic evaluation of squamous cell carcinoma occult primary tumors of the head and neck.

Golusinski P, Di Maio P, Pehlivan B, Colley S, Nankivell P, Kong A, Hartley A, Mehanna H.

Oral Oncol. 2019 Jan;88:145-152. doi: 10.1016/j.oraloncology.2018.11.020. Epub 2018 Nov 30. Review.


Rural-Urban Differences in Baseline Dietary Intake and Physical Activity Levels of Adolescents.

Euler R, Jimenez EY, Sanders S, Kuhlemeier A, Van Horn ML, Cohen D, Gonzales-Pacheco D, Kong AS.

Prev Chronic Dis. 2019 Jan 3;16:E01. doi: 10.5888/pcd16.180200.


Early-life exposure to endocrine disrupting chemicals associates with childhood obesity.

Yang C, Lee HK, Kong APS, Lim LL, Cai Z, Chung ACK.

Ann Pediatr Endocrinol Metab. 2018 Dec;23(4):182-195. doi: 10.6065/apem.2018.23.4.182. Epub 2018 Dec 31.


Effects of Once-Weekly Exenatide on Clinical Outcomes in Patients With Preexisting Cardiovascular Disease.

Mentz RJ, Thompson VP, Aguilar D, Choi J, Gustavson SM, Iqbal N, Kong AP, Öhman P, Sattar N, Scott RS, Wong YW, Holman RR, Hernandez AF.

Circulation. 2018 Nov 27;138(22):2576-2578. doi: 10.1161/CIRCULATIONAHA.118.036811. No abstract available.


DeltaMass: Automated Detection and Visualization of Mass Shifts in Proteomic Open-Search Results.

Avtonomov DM, Kong A, Nesvizhskii AI.

J Proteome Res. 2019 Feb 1;18(2):715-720. doi: 10.1021/acs.jproteome.8b00728. Epub 2018 Dec 17.


Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle.

Ji W, Wang L, He S, Yan L, Li T, Wang J, Kong AT, Yu S, Zhang Y.

PLoS One. 2018 Dec 4;13(12):e0208474. doi: 10.1371/journal.pone.0208474. eCollection 2018.


Paris Saponin II inhibits colorectal carcinogenesis by regulating mitochondrial fission and NF-κB pathway.

Chen M, Ye K, Zhang B, Xin Q, Li P, Kong AN, Wen X, Yang J.

Pharmacol Res. 2019 Jan;139:273-285. doi: 10.1016/j.phrs.2018.11.029. Epub 2018 Nov 22.


Association between educational level and cardiovascular disease and all-cause mortality in patients with type 2 diabetes: a prospective study in the Joint Asia Diabetes Evaluation Program.

Wu H, Lau ES, Kong AP, Ma RC, Ozaki R, Cheung KK, Chow E, Tsang CC, Lau KP, Hui EM, So WY, Gasevic D, Wild SH, Chan JC, Luk A.

Clin Epidemiol. 2018 Oct 25;10:1561-1571. doi: 10.2147/CLEP.S177437. eCollection 2018.


Radiotherapy plus cisplatin or cetuximab in low-risk human papillomavirus-positive oropharyngeal cancer (De-ESCALaTE HPV): an open-label randomised controlled phase 3 trial.

Mehanna H, Robinson M, Hartley A, Kong A, Foran B, Fulton-Lieuw T, Dalby M, Mistry P, Sen M, O'Toole L, Al Booz H, Dyker K, Moleron R, Whitaker S, Brennan S, Cook A, Griffin M, Aynsley E, Rolles M, De Winton E, Chan A, Srinivasan D, Nixon I, Grumett J, Leemans CR, Buter J, Henderson J, Harrington K, McConkey C, Gray A, Dunn J; De-ESCALaTE HPV Trial Group.

Lancet. 2019 Jan 5;393(10166):51-60. doi: 10.1016/S0140-6736(18)32752-1. Epub 2018 Nov 15.


Rheumatoid Arthritis-Interstitial Lung Disease in the United States: Prevalence, Incidence, and Healthcare Costs and Mortality.

Raimundo K, Solomon JJ, Olson AL, Kong AM, Cole AL, Fischer A, Swigris JJ.

J Rheumatol. 2018 Nov 15. pii: jrheum.171315. doi: 10.3899/jrheum.171315. [Epub ahead of print] Erratum in: J Rheumatol. 2019 Feb;46(2):218.


Progression of diabetic kidney disease and trajectory of kidney function decline in Chinese patients with Type 2 diabetes.

Jiang G, Luk AOY, Tam CHT, Xie F, Carstensen B, Lau ESH, Lim CKP, Lee HM, Ng ACW, Ng MCY, Ozaki R, Kong APS, Chow CC, Yang X, Lan HY, Tsui SKW, Fan X, Szeto CC, So WY, Chan JCN, Ma RCW; Hong Kong Diabetes Register TRS Study Group.

Kidney Int. 2019 Jan;95(1):178-187. doi: 10.1016/j.kint.2018.08.026. Epub 2018 Nov 8.


Multiple transmissions of de novo mutations in families.

Jónsson H, Sulem P, Arnadottir GA, Pálsson G, Eggertsson HP, Kristmundsdottir S, Zink F, Kehr B, Hjorleifsson KE, Jensson BÖ, Jonsdottir I, Marelsson SE, Gudjonsson SA, Gylfason A, Jonasdottir A, Jonasdottir A, Stacey SN, Magnusson OT, Thorsteinsdottir U, Masson G, Kong A, Halldorsson BV, Helgason A, Gudbjartsson DF, Stefansson K.

Nat Genet. 2018 Dec;50(12):1674-1680. doi: 10.1038/s41588-018-0259-9. Epub 2018 Nov 5.


Transcriptomic Analysis of Histone Methyltransferase Setd7 Knockdown and Phenethyl Isothiocyanate in Human Prostate Cancer Cells.

Wang C, Sargsyan D, Zhang C, Wu R, Yang Y, Kong AN.

Anticancer Res. 2018 Nov;38(11):6069-6083. doi: 10.21873/anticanres.12957.


Motivational Interviewing to Treat Adolescents With Obesity: A Meta-analysis.

Vallabhan MK, Jimenez EY, Nash JL, Gonzales-Pacheco D, Coakley KE, Noe SR, DeBlieck CJ, Summers LC, Feldstein-Ewing SW, Kong AS.

Pediatrics. 2018 Nov;142(5). pii: e20180733. doi: 10.1542/peds.2018-0733. Epub 2018 Oct 22. Review.


Emerging roles for clinical pharmacometrics in cancer precision medicine.

Nair S, Kong AT.

Curr Pharmacol Rep. 2018 Jun;4(3):276-283. doi: 10.1007/s40495-018-0139-0. Epub 2018 Apr 20.


Background EEG features and prediction of cognitive outcomes in very preterm infants: A systematic review.

Kong AHT, Lai MM, Finnigan S, Ware RS, Boyd RN, Colditz PB.

Early Hum Dev. 2018 Dec;127:74-84. doi: 10.1016/j.earlhumdev.2018.09.015. Epub 2018 Oct 16. Review.


Personalized biomarker-based treatment strategy for patients with squamous cell carcinoma of the head and neck: EORTC position and approach.

Galot R, Le Tourneau C, Guigay J, Licitra L, Tinhofer I, Kong A, Caballero C, Fortpied C, Bogaerts J, Govaerts AS, Staelens D, Raveloarivahy T, Rodegher L, Laes JF, Saada-Bouzid E, Machiels JP.

Ann Oncol. 2018 Dec 1;29(12):2313-2327. doi: 10.1093/annonc/mdy452.


Sophora flavescens Containing-QYJD Formula Activates Nrf2 Anti-Oxidant Response, Blocks Cellular Transformation and Protects Against DSS-Induced Colitis in Mouse Model.

Fang R, Wu R, Zuo Q, Yin R, Zhang C, Wang C, Guo Y, Yang AY, Li W, Lin L, Kong AN.

Am J Chin Med. 2018 Oct 4:1-15. doi: 10.1142/S0192415X18500829. [Epub ahead of print]


Interactive effects of testosterone and the androgen receptor CAG repeat length polymorphism on cardiovascular-renal events and mortality in men with diabetes.

Wong PW, Lee HM, Lau ESH, Lim C, Ma RCW, Kong APS, Chan JCN, Luk AOY.

Diabetes Metab Res Rev. 2019 Jan;35(1):e3081. doi: 10.1002/dmrr.3081. Epub 2018 Oct 23.


Management of the axilla after neo-adjuvant chemotherapy for breast cancer: Sentinel node biopsy and radiotherapy considerations.

Currey A, Patten CR, Bergom C, Wilson JF, Kong AL.

Breast J. 2018 Nov;24(6):902-910. doi: 10.1111/tbj.13116. Epub 2018 Sep 25. Review.


Author Correction: The rate of meiotic gene conversion varies by sex and age.

Halldorsson BV, Hardarson MT, Kehr B, Styrkarsdottir U, Gylfason A, Thorleifsson G, Zink F, Jonasdottir A, Jonasdottir A, Sulem P, Masson G, Thorsteinsdottir U, Helgason A, Kong A, Gudbjartsson DF, Stefansson K.

Nat Genet. 2018 Nov;50(11):1616. doi: 10.1038/s41588-018-0228-3.


The association of socioeconomic status with receipt of neoadjuvant chemotherapy.

Neuner JM, Kong A, Blaes A, Riley D, Chrischilles E, Smallwood A, Lizarraga I, Schroeder M.

Breast Cancer Res Treat. 2018 Sep 19. doi: 10.1007/s10549-018-4954-0. [Epub ahead of print]


Nrf2 deletion results in impaired performance in memory tasks and hyperactivity in mature and aged mice.

Gergues MM, Moiseyenko A, Saad SZ, Kong AN, Wagner GC.

Brain Res. 2018 Dec 15;1701:103-111. doi: 10.1016/j.brainres.2018.08.033. Epub 2018 Sep 5.


A proof-of-concept study to evaluate the efficacy and safety of BTI320 on post-prandial hyperglycaemia in Chinese subjects with pre-diabetes.

Luk AOY, Zee BCY, Chong M, Ozaki R, Rausch CW, Chan MHM, Ma RCW, Kong APS, Chow FCC, Chan JCN.

BMC Endocr Disord. 2018 Aug 31;18(1):59. doi: 10.1186/s12902-018-0288-5.


Electroactive Cu-P-Coupled Moieties Doped in Hierarchically Porous Carbon as Efficient Catalysts for the Oxygen-Reduction Reaction.

Ni Y, Qiao Y, Kong F, Li R, Zhang C, Kong A, Shan Y.

Chem Asian J. 2018 Nov 2;13(21):3314-3320. doi: 10.1002/asia.201801091. Epub 2018 Oct 17.


The dietary flavone luteolin epigenetically activates the Nrf2 pathway and blocks cell transformation in human colorectal cancer HCT116 cells.

Zuo Q, Wu R, Xiao X, Yang C, Yang Y, Wang C, Lin L, Kong AN.

J Cell Biochem. 2018 Nov;119(11):9573-9582. doi: 10.1002/jcb.27275. Epub 2018 Aug 20.


The Expanding Role of Radiosurgery for Brain Metastases.

O'Beirn M, Benghiat H, Meade S, Heyes G, Sawlani V, Kong A, Hartley A, Sanghera P.

Medicines (Basel). 2018 Aug 14;5(3). pii: E90. doi: 10.3390/medicines5030090. Review.


Relatedness disequilibrium regression estimates heritability without environmental bias.

Young AI, Frigge ML, Gudbjartsson DF, Thorleifsson G, Bjornsdottir G, Sulem P, Masson G, Thorsteinsdottir U, Stefansson K, Kong A.

Nat Genet. 2018 Sep;50(9):1304-1310. doi: 10.1038/s41588-018-0178-9. Epub 2018 Aug 13.


Guidance on the management of familial hypercholesterolaemia in Hong Kong: an expert panel consensus viewpoin.

Tomlinson B, Chan JC, Chan WB, Chen WW, Chow FC, Li SK, Kong AP, Ma RC, Siu DC, Tan KC, Wong LK, Yeung VT, But BW, Cheung PT, Fu CC, Tung JY, Wong WC, Yau HC.

Hong Kong Med J. 2018 Aug;24(4):408-415. doi: 10.12809/hkmj187215.


National risk factors for blunt cardiac injury: Hemopneumothorax is the strongest predictor.

Grigorian A, Milliken J, Livingston JK, Spencer D, Gabriel V, Schubl SD, Kong A, Barrios C, Joe V, Nahmias J.

Am J Surg. 2018 Jul 25. pii: S0002-9610(18)30301-5. doi: 10.1016/j.amjsurg.2018.07.043. [Epub ahead of print]


Disparities in retail marketing for menthol cigarettes in the United States, 2015.

Mills SD, Henriksen L, Golden SD, Kurtzman R, Kong AY, Queen TL, Ribisl KM.

Health Place. 2018 Sep;53:62-70. doi: 10.1016/j.healthplace.2018.06.011. Epub 2018 Jul 26.


An engineered Pseudomonas putida can simultaneously degrade organophosphates, pyrethroids and carbamates.

Gong T, Xu X, Dang Y, Kong A, Wu Y, Liang P, Wang S, Yu H, Xu P, Yang C.

Sci Total Environ. 2018 Jul 1;628-629:1258-1265. doi: 10.1016/j.scitotenv.2018.02.143. Epub 2018 Feb 20.


Chronic co-exposure to low levels of brominated flame retardants and heavy metals induces reproductive toxicity in zebrafish.

Chen J, Ma X, Tian L, Kong A, Wang N, Huang C, Yang D.

Toxicol Ind Health. 2018 Sep;34(9):631-639. doi: 10.1177/0748233718779478. Epub 2018 Jul 13.


Diet quality is inversely associated with obesity in Chinese adults with type 2 diabetes.

Cheung LTF, Chan RSM, Ko GTC, Lau ESH, Chow FCC, Kong APS.

Nutr J. 2018 Jul 3;17(1):63. doi: 10.1186/s12937-018-0374-6.


Sudomotor dysfunction independently predicts incident cardiovascular-renal events and all-cause death in type 2 diabetes: the Joint Asia Diabetes Evaluation register.

Lim LL, Fu AWC, Lau ESH, Ozaki R, Cheung KKT, Ma RCW, Luk AOY, Chan JCN, Kong APS.

Nephrol Dial Transplant. 2018 Jun 22. doi: 10.1093/ndt/gfy154. [Epub ahead of print]


Respiratory Syncytial Virus Hospitalizations among U.S. Preterm Infants Compared with Term Infants Before and After the 2014 American Academy of Pediatrics Guidance on Immunoprophylaxis: 2012-2016.

Goldstein M, Krilov LR, Fergie J, McLaurin KK, Wade SW, Diakun D, Lenhart GM, Bloomfield A, Kong AM.

Am J Perinatol. 2018 Dec;35(14):1433-1442. doi: 10.1055/s-0038-1660466. Epub 2018 Jun 19.


Depressive Symptoms, Co-Morbidities, and Glycemic Control in Hong Kong Chinese Elderly Patients With Type 2 Diabetes Mellitus.

Fung ACH, Tse G, Cheng HL, Lau ESH, Luk A, Ozaki R, So TTY, Wong RYM, Tsoh J, Chow E, Wing YK, Chan JCN, Kong APS.

Front Endocrinol (Lausanne). 2018 May 29;9:261. doi: 10.3389/fendo.2018.00261. eCollection 2018.


Pharmacokinetics and Pharmacodynamics of Curcumin in regulating anti-inflammatory and epigenetic gene expression.

Boyanapalli SSS, Huang Y, Su Z, Cheng D, Zhang C, Guo Y, Rao R, Androulakis IP, Kong AN.

Biopharm Drug Dispos. 2018 Jun;39(6):289-297. doi: 10.1002/bdd.2136.


The relationship between patient and tumor characteristics, patterns of breast cancer care, and 5-year survival among elderly women with incident breast cancer.

Kong AL, Nattinger AB, McGinley E, Pezzin LE.

Breast Cancer Res Treat. 2018 Sep;171(2):477-488. doi: 10.1007/s10549-018-4837-4. Epub 2018 Jun 5.


Aspects of Multicomponent Integrated Care Promote Sustained Improvement in Surrogate Clinical Outcomes: A Systematic Review and Meta-analysis.

Lim LL, Lau ESH, Kong APS, Davies MJ, Levitt NS, Eliasson B, Aguilar-Salinas CA, Ning G, Seino Y, So WY, McGill M, Ogle GD, Orchard TJ, Clarke P, Holman RR, Gregg EW, Gagliardino JJ, Chan JCN.

Diabetes Care. 2018 Jun;41(6):1312-1320. doi: 10.2337/dc17-2010. Review.


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