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Items: 1 to 50 of 84

1.

Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion.

Commander R, Wei C, Sharma A, Mouw JK, Burton LJ, Summerbell E, Mahboubi D, Peterson RJ, Konen J, Zhou W, Du Y, Fu H, Shanmugam M, Marcus AI.

Nat Commun. 2020 Mar 24;11(1):1533. doi: 10.1038/s41467-020-15219-7.

2.

The Good, the Bad and the Unknown of CD38 in the Metabolic Microenvironment and Immune Cell Functionality of Solid Tumors.

Konen JM, Fradette JJ, Gibbons DL.

Cells. 2019 Dec 24;9(1). pii: E52. doi: 10.3390/cells9010052. Review.

3.

Intraoperative Ultrasound Guidance With an Ultrasound-Visible Clip: A Practical and Cost-effective Option for Breast Cancer Localization.

Konen J, Murphy S, Berkman A, Ahern TP, Sowden M.

J Ultrasound Med. 2019 Nov 18. doi: 10.1002/jum.15172. [Epub ahead of print]

PMID:
31737930
4.

Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes.

Zoeller EL, Pedro B, Konen J, Dwivedi B, Rupji M, Sundararaman N, Wang L, Horton JR, Zhong C, Barwick BG, Cheng X, Martinez ED, Torres MP, Kowalski J, Marcus AI, Vertino PM.

J Cell Sci. 2019 Oct 9;132(19). pii: jcs231514. doi: 10.1242/jcs.231514.

PMID:
31515279
5.

Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy.

Soundararajan R, Fradette JJ, Konen JM, Moulder S, Zhang X, Gibbons DL, Varadarajan N, Wistuba II, Tripathy D, Bernatchez C, Byers LA, Chang JT, Contreras A, Lim B, Parra ER, Roarty EB, Wang J, Yang F, Barton M, Rosen JM, Mani SA.

Cancers (Basel). 2019 May 24;11(5). pii: E714. doi: 10.3390/cancers11050714. Review.

6.

Ntrk1 Promotes Resistance to PD-1 Checkpoint Blockade in Mesenchymal Kras/p53 Mutant Lung Cancer.

Konen JM, Rodriguez BL, Fradette JJ, Gibson L, Davis D, Minelli R, Peoples MD, Kovacs J, Carugo A, Bristow C, Heffernan T, Gibbons DL.

Cancers (Basel). 2019 Apr 2;11(4). pii: E462. doi: 10.3390/cancers11040462.

7.

The complex ecosystem in non small cell lung cancer invasion.

Haney S, Konen J, Marcus AI, Bazhenov M.

PLoS Comput Biol. 2018 May 24;14(5):e1006131. doi: 10.1371/journal.pcbi.1006131. eCollection 2018 May.

8.

TASI: A software tool for spatial-temporal quantification of tumor spheroid dynamics.

Hou Y, Konen J, Brat DJ, Marcus AI, Cooper LAD.

Sci Rep. 2018 May 8;8(1):7248. doi: 10.1038/s41598-018-25337-4.

9.

Vimentin Is Required for Lung Adenocarcinoma Metastasis via Heterotypic Tumor Cell-Cancer-Associated Fibroblast Interactions during Collective Invasion.

Richardson AM, Havel LS, Koyen AE, Konen JM, Shupe J, Wiles WG 4th, Martin WD, Grossniklaus HE, Sica G, Gilbert-Ross M, Marcus AI.

Clin Cancer Res. 2018 Jan 15;24(2):420-432. doi: 10.1158/1078-0432.CCR-17-1776. Epub 2017 Dec 5.

10.

Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion.

Konen J, Summerbell E, Dwivedi B, Galior K, Hou Y, Rusnak L, Chen A, Saltz J, Zhou W, Boise LH, Vertino P, Cooper L, Salaita K, Kowalski J, Marcus AI.

Nat Commun. 2017 May 12;8:15078. doi: 10.1038/ncomms15078.

11.

Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma.

Gilbert-Ross M, Konen J, Koo J, Shupe J, Robinson BS, Wiles WG 4th, Huang C, Martin WD, Behera M, Smith GH, Hill CE, Rossi MR, Sica GL, Rupji M, Chen Z, Kowalski J, Kasinski AL, Ramalingam SS, Fu H, Khuri FR, Zhou W, Marcus AI.

JCI Insight. 2017 Mar 9;2(5):e90487. doi: 10.1172/jci.insight.90487.

12.

Local alignment vectors reveal cancer cell-induced ECM fiber remodeling dynamics.

Lee B, Konen J, Wilkinson S, Marcus AI, Jiang Y.

Sci Rep. 2017 Jan 3;7:39498. doi: 10.1038/srep39498.

13.

LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion.

Konen J, Wilkinson S, Lee B, Fu H, Zhou W, Jiang Y, Marcus AI.

Mol Biol Cell. 2016 Apr 1;27(7):1069-84. doi: 10.1091/mbc.E15-08-0569. Epub 2016 Feb 10.

14.

Clinical predictors of accurate prehospital stroke recognition.

Oostema JA, Konen J, Chassee T, Nasiri M, Reeves MJ.

Stroke. 2015 Jun;46(6):1513-7. doi: 10.1161/STROKEAHA.115.008650. Epub 2015 Apr 28.

PMID:
25922507
15.

The ubiquitin-conjugating enzyme (E2) Ube2w ubiquitinates the N terminus of substrates.

Scaglione KM, Basrur V, Ashraf NS, Konen JR, Elenitoba-Johnson KS, Todi SV, Paulson HL.

J Biol Chem. 2013 Jun 28;288(26):18784-8. doi: 10.1074/jbc.C113.477596. Epub 2013 May 21.

16.

Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex.

Bakulski KM, Dolinoy DC, Sartor MA, Paulson HL, Konen JR, Lieberman AP, Albin RL, Hu H, Rozek LS.

J Alzheimers Dis. 2012;29(3):571-88. doi: 10.3233/JAD-2012-111223.

17.

The state of diabetes in North Carolina.

Konen J, Page J.

N C Med J. 2011 Sep-Oct;72(5):373-8. Review.

PMID:
22416514
18.

Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP.

Scaglione KM, Zavodszky E, Todi SV, Patury S, Xu P, Rodríguez-Lebrón E, Fischer S, Konen J, Djarmati A, Peng J, Gestwicki JE, Paulson HL.

Mol Cell. 2011 Aug 19;43(4):599-612. doi: 10.1016/j.molcel.2011.05.036.

19.

Cardiovascular and mortality risk prediction and stratification using urinary albumin excretion in older adults ages 68-102: the Cardiovascular Health Study.

Cao JJ, Biggs ML, Barzilay J, Konen J, Psaty BM, Kuller L, Bleyer AJ, Olson J, Wexler J, Summerson J, Cushman M.

Atherosclerosis. 2008 Apr;197(2):806-13. Epub 2007 Sep 17.

PMID:
17875308
20.

Heart disease deaths among firefighters.

Raymond LW, Barringer TA, Konen JC.

N Engl J Med. 2007 Jun 14;356(24):2535-6; author reply 2536-7. No abstract available.

PMID:
17575582
21.

Improving diabetes care among low-income North Carolinians: Project IDEAL.

Bell RA, Camacho F, Duren-Winfield VT, Bonds DE, Anderson RT, Konen JC, Goff DC Jr.

N C Med J. 2005 Mar-Apr;66(2):96-102.

PMID:
15952458
22.

Stress testing in the medical evaluation for hazardous materials duty: results and consequences in three groups of candidates.

Raymond LW, Barringer TA, Konen JC.

J Occup Environ Med. 2005 May;47(5):493-502.

PMID:
15891528
23.
24.

Why are we surprised by our failures? The bewildering complexity of diabetes care.

Konen JC.

N C Med J. 2003 Mar-Apr;64(2):80-2. No abstract available.

PMID:
12774737
26.

The effects of continuous 5-HT(3) receptor antagonist administration on the subsequent behavioral response to cocaine.

King GR, Pinto G, Konen J, Castro G, Tran S, Hilburn C.

Eur J Pharmacol. 2002 Aug 9;449(3):253-9.

PMID:
12167467
27.

The effects of continuous cocaine duration on the induction of behavioral tolerance and dopamine autoreceptor function.

King GR, Pinto G, Konen J, Hillburn C, Tran S, Love W, Cayse R, Castro G.

Eur J Pharmacol. 2002 Jun 20;446(1-3):111-8.

PMID:
12098592
28.

Cigarette smoking and erectile dysfunction.

Spangler JG, Summerson JH, Bell R, Konen JC.

J Fam Pract. 2002 Jan;51(1):81. No abstract available.

PMID:
11927070
29.

The state of community medicine training in family practice residency programs.

Plescia M, Konen JC, Lincourt A.

Fam Med. 2002 Mar;34(3):177-82.

PMID:
11922532
30.

Quality of diabetes care among low-income patients in North Carolina.

Bell RA, Camacho F, Goonan K, Duren-Winfield V, Anderson RT, Konen JC, Goff DC Jr.

Am J Prev Med. 2001 Aug;21(2):124-31.

PMID:
11457632
31.

Smoking status and psychosocial variables in type 1 diabetes mellitus.

Spangler JG, Summerso JH, Bell RA, Konen JC.

Addict Behav. 2001 Jan-Feb;26(1):21-9.

PMID:
11196290
32.

Smoking, hypertension, and erectile dysfunction.

Spangler JG, Summerson JH, Bell RA, Konen JC.

J Fam Pract. 2001 Jan;50(1):73. No abstract available.

PMID:
11195487
33.

Prevalence and nature of orofacial and dental problems in family medicine.

Lockhart PB, Mason DK, Konen JC, Kent ML, Gibson J.

Arch Fam Med. 2000 Nov-Dec;9(10):1009-12.

PMID:
11115200
34.

Racial differences in symptoms and complications in adults with type 2 diabetes mellitus.

Konen JC, Summerson JH, Bell RA, Curtis LG.

Ethn Health. 1999 Feb-May;4(1-2):39-49.

PMID:
10887461
36.

Project IDEAL. Improving Diabetes Education, Access to care and Living. A plan to reduce the burden of diabetes in North Carolina.

Duren-Winfield VT, Bell RA, Anderson RT, Frank JH, Konen JC, Goff DC Jr.

N C Med J. 2000 Jan-Feb;61(1):420-2. No abstract available.

PMID:
10647264
37.

Abnormal urinary protein excretion in African Americans with type 2 diabetes mellitus.

Konen JC, Summerson JH, Bell RA.

Ethn Dis. 1999 Winter;9(1):3-9.

PMID:
10355470
38.

Health education to increase screening for cervical cancer among Lumbee Indian women in North Carolina.

Dignan MB, Michielutte R, Wells HB, Sharp P, Blinson K, Case LD, Bell R, Konen J, Davis S, McQuellon RP.

Health Educ Res. 1998 Dec;13(4):545-56.

PMID:
10345905
39.

Association of gender with symptoms and complications in type II diabetes mellitus.

Summerson JH, Spangler JG, Bell RA, Shelton BJ, Konen JC.

Womens Health Issues. 1999 May-Jun;9(3):176-82.

PMID:
10340023
40.

Body fat, fat distribution, and psychosocial factors among patients with Type 2 diabetes mellitus.

Bell RA, Summerson JH, Spangler JG, Konen JC.

Behav Med. 1998 Fall;24(3):138-43.

PMID:
9850808
41.

Hyperinsulinemia in hypertension: associations with race, abdominal obesity, and hyperlipidemia.

Spangler JG, Bell RA, Summerson JH, Konen JC.

Arch Fam Med. 1998 Jan-Feb;7(1):53-6.

PMID:
9443700
42.

Correlates of abnormal urinary albumin excretion rates among primary care patients with essential hypertension.

Spangler JG, Bell RA, Summerson JH, Konen JC.

J Am Board Fam Pract. 1997 May-Jun;10(3):180-4.

PMID:
9159655
43.

Women's cardiovascular health.

Sharp PC, Konen JC.

Prim Care. 1997 Mar;24(1):1-14. Review.

PMID:
9016726
44.

Whose life is it anyway?

Konen JC.

Arch Fam Med. 1997 Jan-Feb;6(1):77-8. No abstract available.

PMID:
9003177
45.

Sleep history is neglected diagnostic information. Challenges for primary care physicians.

Haponik EF, Frye AW, Richards B, Wymer A, Hinds A, Pearce K, McCall V, Konen J.

J Gen Intern Med. 1996 Dec;11(12):759-61.

PMID:
9016425
46.

Effectiveness of health education to increase screening for cervical cancer among eastern-band Cherokee Indian women in North Carolina.

Dignan M, Michielutte R, Blinson K, Wells HB, Case LD, Sharp P, Davis S, Konen J, McQuellon RP.

J Natl Cancer Inst. 1996 Nov 20;88(22):1670-6.

PMID:
8931612
47.
48.

Four factors of clinical decision making: a teaching model.

Leist JC, Konen JC.

Acad Med. 1996 Jun;71(6):644-6.

PMID:
9125921
49.
50.

Symptoms and complications of adult diabetic patients in a family practice.

Konen JC, Curtis LG, Summerson JH.

Arch Fam Med. 1996 Mar;5(3):135-45.

PMID:
8620254

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