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Items: 1 to 50 of 291

1.

Engineered membrane protein antigens successfully induce antibodies against extracellular regions of claudin-5.

Hashimoto Y, Zhou W, Hamauchi K, Shirakura K, Doi T, Yagi K, Sawasaki T, Okada Y, Kondoh M, Takeda H.

Sci Rep. 2018 May 30;8(1):8383. doi: 10.1038/s41598-018-26560-9.

2.

The Clinical Innovation Network: a policy for promoting development of drugs and medical devices in Japan.

Matsushita S, Tachibana K, Kondoh M.

Drug Discov Today. 2018 May 24. pii: S1359-6446(18)30026-6. doi: 10.1016/j.drudis.2018.05.026. [Epub ahead of print]

PMID:
29803934
3.

Density-dependent interspecific interactions and the complexity-stability relationship.

Kawatsu K, Kondoh M.

Proc Biol Sci. 2018 May 30;285(1879). pii: 20180698. doi: 10.1098/rspb.2018.0698.

4.

Using food network unfolding to evaluate food-web complexity in terms of biodiversity: theory and applications.

Kato Y, Kondoh M, Ishikawa NF, Togashi H, Kohmatsu Y, Yoshimura M, Yoshimizu C, Haraguchi TF, Osada Y, Ohte N, Tokuchi N, Okuda N, Miki T, Tayasu I.

Ecol Lett. 2018 Jul;21(7):1065-1074. doi: 10.1111/ele.12973. Epub 2018 May 17.

PMID:
29774660
5.

Angubindin-1 opens the blood-brain barrier in vivo for delivery of antisense oligonucleotide to the central nervous system.

Zeniya S, Kuwahara H, Daizo K, Watari A, Kondoh M, Yoshida-Tanaka K, Kaburagi H, Asada K, Nagata T, Nagahama M, Yagi K, Yokota T.

J Control Release. 2018 Aug 10;283:126-134. doi: 10.1016/j.jconrel.2018.05.010. Epub 2018 May 17.

6.

Safety evaluation of a human chimeric monoclonal antibody that recognizes the extracellular loop domain of claudin-2.

Hashimoto Y, Hata T, Tada M, Iida M, Watari A, Okada Y, Doi T, Kuniyasu H, Yagi K, Kondoh M.

Eur J Pharm Sci. 2018 May 30;117:161-167. doi: 10.1016/j.ejps.2018.02.016. Epub 2018 Feb 13.

PMID:
29448044
7.

Impaired airway mucociliary function reduces antigen-specific IgA immune response to immunization with a claudin-4-targeting nasal vaccine in mice.

Suzuki H, Nagatake T, Nasu A, Lan H, Ikegami K, Setou M, Hamazaki Y, Kiyono H, Yagi K, Kondoh M, Kunisawa J.

Sci Rep. 2018 Feb 13;8(1):2904. doi: 10.1038/s41598-018-21120-7.

8.

Monoclonal antibodies against occludin completely prevented hepatitis C virus infection in a mouse model.

Shimizu Y, Shirasago Y, Kondoh M, Suzuki T, Wakita T, Hanada K, Yagi K, Fukasawa M.

J Virol. 2018 Feb 7. pii: JVI.02258-17. doi: 10.1128/JVI.02258-17. [Epub ahead of print]

PMID:
29437969
9.

Fluctuating interaction network and time-varying stability of a natural fish community.

Ushio M, Hsieh CH, Masuda R, Deyle ER, Ye H, Chang CW, Sugihara G, Kondoh M.

Nature. 2018 Feb 15;554(7692):360-363. doi: 10.1038/nature25504. Epub 2018 Feb 7.

PMID:
29414940
10.

Lignosulfonic acid attenuates NF-κB activation and intestinal epithelial barrier dysfunction induced by TNF-α/IFN-γ in Caco-2 cells.

Matsuhisa K, Watari A, Iwamoto K, Kondoh M, Yagi K.

J Nat Med. 2018 Mar;72(2):448-455. doi: 10.1007/s11418-017-1167-5. Epub 2017 Dec 23.

PMID:
29275476
11.

Identification of claudin-4 binder that attenuates tight junction barrier function by TR-FRET-based screening assay.

Watari A, Kodaka M, Matsuhisa K, Sakamoto Y, Hisaie K, Kawashita N, Takagi T, Yamagishi Y, Suzuki H, Tsujino H, Yagi K, Kondoh M.

Sci Rep. 2017 Nov 6;7(1):14514. doi: 10.1038/s41598-017-15108-y.

12.

Dodecylmaltoside Modulates Bicellular Tight Junction Contacts To Promote Enhanced Permeability.

Gradauer K, Iida M, Watari A, Kataoka M, Yamashita S, Kondoh M, Buckley ST.

Mol Pharm. 2017 Dec 4;14(12):4734-4740. doi: 10.1021/acs.molpharmaceut.7b00297. Epub 2017 Oct 27.

PMID:
28985076
13.

Development of a Quenchbody for the Detection and Imaging of the Cancer-Related Tight-Junction-Associated Membrane Protein Claudin.

Jeong HJ, Kawamura T, Iida M, Kawahigashi Y, Takigawa M, Ohmuro-Matsuyama Y, Chung CI, Dong J, Kondoh M, Ueda H.

Anal Chem. 2017 Oct 17;89(20):10783-10789. doi: 10.1021/acs.analchem.7b02047. Epub 2017 Oct 3.

PMID:
28972746
14.

Creation of a Claudin-2 Binder and Its Tight Junction-Modulating Activity in a Human Intestinal Model.

Takigawa M, Iida M, Nagase S, Suzuki H, Watari A, Tada M, Okada Y, Doi T, Fukasawa M, Yagi K, Kunisawa J, Kondoh M.

J Pharmacol Exp Ther. 2017 Dec;363(3):444-451. doi: 10.1124/jpet.117.242214. Epub 2017 Sep 19.

PMID:
28928120
15.

Claudin-5-Binders Enhance Permeation of Solutes across the Blood-Brain Barrier in a Mammalian Model.

Hashimoto Y, Shirakura K, Okada Y, Takeda H, Endo K, Tamura M, Watari A, Sadamura Y, Sawasaki T, Doi T, Yagi K, Kondoh M.

J Pharmacol Exp Ther. 2017 Nov;363(2):275-283. doi: 10.1124/jpet.117.243014. Epub 2017 Aug 17.

PMID:
28819070
16.

Environmental DNA enables detection of terrestrial mammals from forest pond water.

Ushio M, Fukuda H, Inoue T, Makoto K, Kishida O, Sato K, Murata K, Nikaido M, Sado T, Sato Y, Takeshita M, Iwasaki W, Yamanaka H, Kondoh M, Miya M.

Mol Ecol Resour. 2017 Nov;17(6):e63-e75. doi: 10.1111/1755-0998.12690. Epub 2017 Jun 11.

PMID:
28603873
17.

Angubindin-1, a novel paracellular absorption enhancer acting at the tricellular tight junction.

Krug SM, Hayaishi T, Iguchi D, Watari A, Takahashi A, Fromm M, Nagahama M, Takeda H, Okada Y, Sawasaki T, Doi T, Yagi K, Kondoh M.

J Control Release. 2017 Aug 28;260:1-11. doi: 10.1016/j.jconrel.2017.05.024. Epub 2017 May 18.

PMID:
28528740
18.

Integrated trophic position decreases in more diverse communities of stream food webs.

Ishikawa NF, Chikaraishi Y, Ohkouchi N, Murakami AR, Tayasu I, Togashi H, Okano JI, Sakai Y, Iwata T, Kondoh M, Okuda N.

Sci Rep. 2017 May 18;7(1):2130. doi: 10.1038/s41598-017-02155-8.

19.

Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer.

Hashimoto Y, Fukasawa M, Kuniyasu H, Yagi K, Kondoh M.

Ann N Y Acad Sci. 2017 Jun;1397(1):5-16. doi: 10.1111/nyas.13337. Epub 2017 Apr 17. Review.

PMID:
28415141
20.

Rebeccamycin Attenuates TNF-α-Induced Intestinal Epithelial Barrier Dysfunction by Inhibiting Myosin Light Chain Kinase Production.

Watari A, Sakamoto Y, Hisaie K, Iwamoto K, Fueta M, Yagi K, Kondoh M.

Cell Physiol Biochem. 2017;41(5):1924-1934. doi: 10.1159/000472367. Epub 2017 Apr 7.

21.

Cellular internalization, transcellular transport, and cellular effects of silver nanoparticles in polarized Caco-2 cells following apical or basolateral exposure.

Imai S, Morishita Y, Hata T, Kondoh M, Yagi K, Gao JQ, Nagano K, Higashisaka K, Yoshioka Y, Tsutsumi Y.

Biochem Biophys Res Commun. 2017 Mar 11;484(3):543-549. doi: 10.1016/j.bbrc.2017.01.114. Epub 2017 Jan 24.

PMID:
28130106
22.

Environmental DNA metabarcoding reveals local fish communities in a species-rich coastal sea.

Yamamoto S, Masuda R, Sato Y, Sado T, Araki H, Kondoh M, Minamoto T, Miya M.

Sci Rep. 2017 Jan 12;7:40368. doi: 10.1038/srep40368.

23.

Conformational and Intermolecular Interaction Dynamics of Photolyase/Cryptochrome Proteins Monitored by the Time-Resolved Diffusion Technique.

Kondoh M, Terazima M.

Photochem Photobiol. 2017 Jan;93(1):15-25. doi: 10.1111/php.12681. Epub 2017 Jan 9. Review.

PMID:
27925276
24.

Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody.

Hashimoto Y, Kawahigashi Y, Hata T, Li X, Watari A, Tada M, Ishii-Watabe A, Okada Y, Doi T, Fukasawa M, Kuniyasu H, Yagi K, Kondoh M.

Pharmacol Res Perspect. 2016 Sep 27;4(5):e00266. eCollection 2016 Oct.

25.

Roles of the first-generation claudin binder, Clostridium perfringens enterotoxin, in the diagnosis and claudin-targeted treatment of epithelium-derived cancers.

Hashimoto Y, Yagi K, Kondoh M.

Pflugers Arch. 2017 Jan;469(1):45-53. doi: 10.1007/s00424-016-1878-6. Epub 2016 Sep 15. Review.

PMID:
27629072
26.

Current progress in a second-generation claudin binder, anti-claudin antibody, for clinical applications.

Hashimoto Y, Yagi K, Kondoh M.

Drug Discov Today. 2016 Oct;21(10):1711-1718. doi: 10.1016/j.drudis.2016.07.004. Epub 2016 Jul 12. Review.

PMID:
27422269
27.

Generation and characterization of a human-mouse chimeric antibody against the extracellular domain of claudin-1 for cancer therapy using a mouse model.

Hashimoto Y, Tada M, Iida M, Nagase S, Hata T, Watari A, Okada Y, Doi T, Fukasawa M, Yagi K, Kondoh M.

Biochem Biophys Res Commun. 2016 Aug 12;477(1):91-5. doi: 10.1016/j.bbrc.2016.06.025. Epub 2016 Jun 8.

PMID:
27286708
28.

Importance of Atomic Contacts in Vibrational Energy Flow in Proteins.

Kondoh M, Mizuno M, Mizutani Y.

J Phys Chem Lett. 2016 Jun 2;7(11):1950-4. doi: 10.1021/acs.jpclett.6b00785. Epub 2016 May 12.

PMID:
27164418
29.

Food-web complexity, meta-community complexity and community stability.

Mougi A, Kondoh M.

Sci Rep. 2016 Apr 13;6:24478. doi: 10.1038/srep24478.

30.

Correction: Environmental DNA as a 'Snapshot' of Fish Distribution: A Case Study of Japanese Jack Mackerel in Maizuru Bay, Sea of Japan.

Yamamoto S, Minami K, Fukaya K, Takahashi K, Sawada H, Murakami H, Tsuji S, Hashizume H, Kubonaga S, Horiuchi T, Hongo M, Nishida J, Okugawa Y, Fujiwara A, Fukuda M, Hidaka S, Suzuki KW, Miya M, Araki H, Yamanaka H, Maruyama A, Miyashita K, Masuda R, Minamoto T, Kondoh M.

PLoS One. 2016 Apr 4;11(4):e0153291. doi: 10.1371/journal.pone.0153291. eCollection 2016. No abstract available.

31.

Claudin-4 binder C-CPE 194 enhances effects of anticancer agents on pancreatic cancer cell lines via a MAPK pathway.

Kono T, Kondoh M, Kyuno D, Ito T, Kimura Y, Imamura M, Kohno T, Konno T, Furuhata T, Sawada N, Hirata K, Kojima T.

Pharmacol Res Perspect. 2015 Dec 20;3(6):e00196. doi: 10.1002/prp2.196. eCollection 2015 Dec.

32.

Environmental DNA as a 'Snapshot' of Fish Distribution: A Case Study of Japanese Jack Mackerel in Maizuru Bay, Sea of Japan.

Yamamoto S, Minami K, Fukaya K, Takahashi K, Sawada H, Murakami H, Tsuji S, Hashizume H, Kubonaga S, Horiuchi T, Hongo M, Nishida J, Okugawa Y, Fujiwara A, Fukuda M, Hidaka S, Suzuki KW, Miya M, Araki H, Yamanaka H, Maruyama A, Miyashita K, Masuda R, Minamoto T, Kondoh M.

PLoS One. 2016 Mar 2;11(3):e0149786. doi: 10.1371/journal.pone.0149786. eCollection 2016. Erratum in: PLoS One. 2016;11(4):e0153291.

33.

Occludin-Knockout Human Hepatic Huh7.5.1-8-Derived Cells Are Completely Resistant to Hepatitis C Virus Infection.

Shirasago Y, Shimizu Y, Tanida I, Suzuki T, Suzuki R, Sugiyama K, Wakita T, Hanada K, Yagi K, Kondoh M, Fukasawa M.

Biol Pharm Bull. 2016 May 1;39(5):839-48. doi: 10.1248/bpb.b15-01023. Epub 2016 Feb 17.

34.

Checkpoint Kinase 1 Activation Enhances Intestinal Epithelial Barrier Function via Regulation of Claudin-5 Expression.

Watari A, Hasegawa M, Yagi K, Kondoh M.

PLoS One. 2016 Jan 4;11(1):e0145631. doi: 10.1371/journal.pone.0145631. eCollection 2016.

35.

MiFish, a set of universal PCR primers for metabarcoding environmental DNA from fishes: detection of more than 230 subtropical marine species.

Miya M, Sato Y, Fukunaga T, Sado T, Poulsen JY, Sato K, Minamoto T, Yamamoto S, Yamanaka H, Araki H, Kondoh M, Iwasaki W.

R Soc Open Sci. 2015 Jul 22;2(7):150088. doi: 10.1098/rsos.150088. eCollection 2015 Jul.

36.

Renoprotective effect of long acting thioredoxin by modulating oxidative stress and macrophage migration inhibitory factor against rhabdomyolysis-associated acute kidney injury.

Nishida K, Watanabe H, Ogaki S, Kodama A, Tanaka R, Imafuku T, Ishima Y, Chuang VT, Toyoda M, Kondoh M, Wu Q, Fukagawa M, Otagiri M, Maruyama T.

Sci Rep. 2015 Sep 28;5:14471. doi: 10.1038/srep14471.

37.

Pro-chemotherapeutic effects of antibody against extracellular domain of claudin-4 in bladder cancer.

Kuwada M, Chihara Y, Luo Y, Li X, Nishiguchi Y, Fujiwara R, Sasaki T, Fujii K, Ohmori H, Fujimoto K, Kondoh M, Kuniyasu H.

Cancer Lett. 2015 Dec 1;369(1):212-21. doi: 10.1016/j.canlet.2015.08.019. Epub 2015 Sep 2.

PMID:
26342407
38.

Claudin-1 Binder Enhances Epidermal Permeability in a Human Keratinocyte Model.

Nakajima M, Nagase S, Iida M, Takeda S, Yamashita M, Watari A, Shirasago Y, Fukasawa M, Takeda H, Sawasaki T, Yagi K, Kondoh M.

J Pharmacol Exp Ther. 2015 Sep;354(3):440-7. doi: 10.1124/jpet.115.225391. Epub 2015 Jul 2.

39.

Claudin-binder C-CPE mutants enhance permeability of insulin across human nasal epithelial cells.

Kojima T, Kondoh M, Keira T, Takano KI, Kakuki T, Kaneko Y, Miyata R, Nomura K, Obata K, Kohno T, Konno T, Sawada N, Himi T.

Drug Deliv. 2016 Oct;23(8):2703-2710. Epub 2015 Jun 2.

PMID:
26036653
40.

C-Terminal Clostridium perfringens Enterotoxin-Mediated Antigen Delivery for Nasal Pneumococcal Vaccine.

Suzuki H, Watari A, Hashimoto E, Yonemitsu M, Kiyono H, Yagi K, Kondoh M, Kunisawa J.

PLoS One. 2015 May 27;10(5):e0126352. doi: 10.1371/journal.pone.0126352. eCollection 2015.

41.

Anti-HCV effect of Lentinula edodes mycelia solid culture extracts and low-molecular-weight lignin.

Matsuhisa K, Yamane S, Okamoto T, Watari A, Kondoh M, Matsuura Y, Yagi K.

Biochem Biophys Res Commun. 2015 Jun 19;462(1):52-7. doi: 10.1016/j.bbrc.2015.04.104. Epub 2015 Apr 29.

PMID:
25935479
42.

Use of cell-based screening to identify small-molecule compounds that modulate claudin-4 expression.

Watari A, Hashegawa M, Muangman T, Yagi K, Kondoh M.

Biotechnol Lett. 2015 Jun;37(6):1177-85. doi: 10.1007/s10529-015-1791-7. Epub 2015 Feb 21.

PMID:
25700824
43.

Monoclonal antibodies against extracellular domains of claudin-1 block hepatitis C virus infection in a mouse model.

Fukasawa M, Nagase S, Shirasago Y, Iida M, Yamashita M, Endo K, Yagi K, Suzuki T, Wakita T, Hanada K, Kuniyasu H, Kondoh M.

J Virol. 2015 May;89(9):4866-79. doi: 10.1128/JVI.03676-14. Epub 2015 Feb 11.

44.

Discovery of anti-claudin-1 antibodies as candidate therapeutics against hepatitis C virus.

Yamashita M, Iida M, Tada M, Shirasago Y, Fukasawa M, Nagase S, Watari A, Ishii-Watabe A, Yagi K, Kondoh M.

J Pharmacol Exp Ther. 2015 Apr;353(1):112-8. doi: 10.1124/jpet.114.217653. Epub 2015 Jan 27.

45.

Homoharringtonine increases intestinal epithelial permeability by modulating specific claudin isoforms in Caco-2 cell monolayers.

Watari A, Hashegawa M, Yagi K, Kondoh M.

Eur J Pharm Biopharm. 2015 Jan;89:232-8. doi: 10.1016/j.ejpb.2014.12.012. Epub 2014 Dec 13.

PMID:
25513955
46.

The release rate of environmental DNA from juvenile and adult fish.

Maruyama A, Nakamura K, Yamanaka H, Kondoh M, Minamoto T.

PLoS One. 2014 Dec 5;9(12):e114639. doi: 10.1371/journal.pone.0114639. eCollection 2014. Erratum in: PLoS One. 2015;10(3):e0118727.

47.

Development of an anti-claudin-3 and -4 bispecific monoclonal antibody for cancer diagnosis and therapy.

Li X, Iida M, Tada M, Watari A, Kawahigashi Y, Kimura Y, Yamashita T, Ishii-Watabe A, Uno T, Fukasawa M, Kuniyasu H, Yagi K, Kondoh M.

J Pharmacol Exp Ther. 2014 Oct;351(1):206-13. doi: 10.1124/jpet.114.216911. Epub 2014 Aug 12.

48.

Beneficial effects of heat-treated Enterococcus faecalis FK-23 on high-fat diet-induced hepatic steatosis in mice.

Kondoh M, Shimada T, Fukada K, Morita M, Katada K, Higashimura Y, Mizushima K, Okamori M, Naito Y, Yoshikawa T.

Br J Nutr. 2014 Sep 28;112(6):868-75. doi: 10.1017/S0007114514001792. Epub 2014 Aug 4.

PMID:
25089585
49.

Stability of competition-antagonism-mutualism hybrid community and the role of community network structure.

Mougi A, Kondoh M.

J Theor Biol. 2014 Nov 7;360:54-58. doi: 10.1016/j.jtbi.2014.06.030. Epub 2014 Jul 5.

PMID:
25008419
50.

Liquid-sheet jets for terahertz spectroscopy.

Kondoh M, Tsubouchi M.

Opt Express. 2014 Jun 16;22(12):14135-47. doi: 10.1364/OE.22.014135.

PMID:
24977512

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