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Items: 1 to 50 of 75

1.

Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo.

Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K, Fujita J.

Sci Signal. 2019 Mar 26;12(574). pii: eaao7232. doi: 10.1126/scisignal.aao7232.

PMID:
30914484
2.

Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation.

Takimoto A, Kokubu C, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y, Shukunami C.

Sci Rep. 2019 Mar 14;9(1):4605. doi: 10.1038/s41598-019-40810-4.

3.

Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation.

Yasuda K, Kitagawa Y, Kawakami R, Isaka Y, Watanabe H, Kondoh G, Kohwi-Shigematsu T, Sakaguchi S, Hirota K.

Nat Commun. 2019 Feb 1;10(1):549. doi: 10.1038/s41467-019-08404-w.

4.

Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis.

Hirota K, Hashimoto M, Ito Y, Matsuura M, Ito H, Tanaka M, Watanabe H, Kondoh G, Tanaka A, Yasuda K, Kopf M, Potocnik AJ, Stockinger B, Sakaguchi N, Sakaguchi S.

Immunity. 2018 Jun 19;48(6):1220-1232.e5. doi: 10.1016/j.immuni.2018.04.009. Epub 2018 May 22.

5.

Stem cell niche-specific Ebf3 maintains the bone marrow cavity.

Seike M, Omatsu Y, Watanabe H, Kondoh G, Nagasawa T.

Genes Dev. 2018 Mar 1;32(5-6):359-372. doi: 10.1101/gad.311068.117. Epub 2018 Mar 21.

6.

Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.

Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, Kuchimaru T, Sakamoto T, Watanabe H, Kondoh G, Kizaka-Kondoh S.

Oncotarget. 2018 Jan 29;9(13):11209-11226. doi: 10.18632/oncotarget.24359. eCollection 2018 Feb 16.

7.

PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.

Morita M, Sato T, Nomura M, Sakamoto Y, Inoue Y, Tanaka R, Ito S, Kurosawa K, Yamaguchi K, Sugiura Y, Takizaki H, Yamashita Y, Katakura R, Sato I, Kawai M, Okada Y, Watanabe H, Kondoh G, Matsumoto S, Kishimoto A, Obata M, Matsumoto M, Fukuhara T, Motohashi H, Suematsu M, Komatsu M, Nakayama KI, Watanabe T, Soga T, Shima H, Maemondo M, Tanuma N.

Cancer Cell. 2018 Mar 12;33(3):355-367.e7. doi: 10.1016/j.ccell.2018.02.004.

8.

Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes.

Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y.

Sci Rep. 2018 Feb 16;8(1):3155. doi: 10.1038/s41598-018-21194-3.

9.

Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors.

Ohashi M, Umemura Y, Koike N, Tsuchiya Y, Inada Y, Watanabe H, Tanaka T, Minami Y, Ukimura O, Miki T, Tajiri T, Kondoh G, Yamada Y, Yagita K.

Genes Cells. 2018 Feb;23(2):60-69. doi: 10.1111/gtc.12552. Epub 2017 Dec 22.

10.

Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.

Hara H, Miyata H, Das NR, Chida J, Yoshimochi T, Uchiyama K, Watanabe H, Kondoh G, Yokoyama T, Sakaguchi S.

J Virol. 2017 Dec 14;92(1). pii: e01368-17. doi: 10.1128/JVI.01368-17. Print 2018 Jan 1.

11.

PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.

Mochizuki AL, Katanaya A, Hayashi E, Hosokawa M, Moribe E, Motegi A, Ishiai M, Takata M, Kondoh G, Watanabe H, Nakatsuji N, Chuma S.

Mol Cell Biol. 2017 Nov 13;37(23). pii: e00117-17. doi: 10.1128/MCB.00117-17. Print 2017 Dec 1.

12.

Lethality of mice bearing a knockout of the Ngly1-gene is partially rescued by the additional deletion of the Engase gene.

Fujihira H, Masahara-Negishi Y, Tamura M, Huang C, Harada Y, Wakana S, Takakura D, Kawasaki N, Taniguchi N, Kondoh G, Yamashita T, Funakoshi Y, Suzuki T.

PLoS Genet. 2017 Apr 20;13(4):e1006696. doi: 10.1371/journal.pgen.1006696. eCollection 2017 Apr.

13.

Lipid raft dynamics linked to sperm competency for fertilization in mice.

Watanabe H, Takeda R, Hirota K, Kondoh G.

Genes Cells. 2017 May;22(5):493-500. doi: 10.1111/gtc.12491. Epub 2017 Apr 20.

14.

Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system.

Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C.

Sci Rep. 2017 Mar 22;7:45010. doi: 10.1038/srep45010.

15.

Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.

Das NR, Miyata H, Hara H, Uchiyama K, Chida J, Yano M, Watanabe H, Kondoh G, Sakaguchi S.

Arch Virol. 2017 Jul;162(7):1867-1876. doi: 10.1007/s00705-017-3295-3. Epub 2017 Mar 2.

PMID:
28255815
16.

Disruption of MeCP2 attenuates circadian rhythm in CRISPR/Cas9-based Rett syndrome model mouse.

Tsuchiya Y, Minami Y, Umemura Y, Watanabe H, Ono D, Nakamura W, Takahashi T, Honma S, Kondoh G, Matsuishi T, Yagita K.

Genes Cells. 2015 Dec;20(12):992-1005. doi: 10.1111/gtc.12305. Epub 2015 Oct 12.

17.

Generation of Helios reporter mice and an evaluation of the suppressive capacity of Helios(+) regulatory T cells in vitro.

Sugita K, Hanakawa S, Honda T, Kondoh G, Miyachi Y, Kabashima K, Nomura T.

Exp Dermatol. 2015 Jul;24(7):554-6. doi: 10.1111/exd.12711. Epub 2015 May 4.

18.

Lipocalin 2 binds to membrane phosphatidylethanolamine to induce lipid raft movement in a PKA-dependent manner and modulates sperm maturation.

Watanabe H, Takeo T, Tojo H, Sakoh K, Berger T, Nakagata N, Mak TW, Kondoh G.

Development. 2014 May;141(10):2157-64. doi: 10.1242/dev.105148.

19.

Female-specific rectal carcinogenesis in cyclin D1b transgenic mice.

Kim CJ, Tambe Y, Mukaisho K, Sugihara H, Isono T, Sonoda H, Shimizu T, Kondoh G, Inoue H.

Carcinogenesis. 2014 Jan;35(1):227-36. doi: 10.1093/carcin/bgt293. Epub 2013 Aug 23.

PMID:
23975835
20.

An in vitro ES cell-based clock recapitulation assay model identifies CK2α as an endogenous clock regulator.

Umemura Y, Yoshida J, Wada M, Tsuchiya Y, Minami Y, Watanabe H, Kondoh G, Takeda J, Inokawa H, Horie K, Yagita K.

PLoS One. 2013 Jun 28;8(6):e67241. doi: 10.1371/journal.pone.0067241. Print 2013.

21.

Expression of TEX101, regulated by ACE, is essential for the production of fertile mouse spermatozoa.

Fujihara Y, Tokuhiro K, Muro Y, Kondoh G, Araki Y, Ikawa M, Okabe M.

Proc Natl Acad Sci U S A. 2013 May 14;110(20):8111-6. doi: 10.1073/pnas.1222166110. Epub 2013 Apr 30.

22.

Mammalian carboxylesterase (CES) releases GPI-anchored proteins from the cell surface upon lipid raft fluidization.

Orihashi K, Tojo H, Okawa K, Tashima Y, Morita T, Kondoh G.

Biol Chem. 2012 Mar;393(3):169-76. doi: 10.1515/hsz-2011-0269.

PMID:
22718632
23.

The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation.

Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K.

J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28. doi: 10.1242/jcs.089748.

24.

Jmjd5, an H3K36me2 histone demethylase, modulates embryonic cell proliferation through the regulation of Cdkn1a expression.

Ishimura A, Minehata K, Terashima M, Kondoh G, Hara T, Suzuki T.

Development. 2012 Feb;139(4):749-59. doi: 10.1242/dev.074138. Epub 2012 Jan 12.

25.

Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging.

Kadonosono T, Kuchimaru T, Yamada S, Takahashi Y, Murakami A, Tani T, Watanabe H, Tanaka T, Hirota K, Inoue M, Tsukamoto T, Toyoda T, Urano K, Machida K, Eto T, Ogura T, Tsutsumi H, Ito M, Hiraoka M, Kondoh G, Kizaka-Kondoh S.

PLoS One. 2011;6(11):e26640. doi: 10.1371/journal.pone.0026640. Epub 2011 Nov 10.

26.

Mouse sperm undergo GPI-anchored protein release associated with lipid raft reorganization and acrosome reaction to acquire fertility.

Watanabe H, Kondoh G.

J Cell Sci. 2011 Aug 1;124(Pt 15):2573-81. doi: 10.1242/jcs.086967. Epub 2011 Jul 12.

27.

Tudor domain containing 7 (Tdrd7) is essential for dynamic ribonucleoprotein (RNP) remodeling of chromatoid bodies during spermatogenesis.

Tanaka T, Hosokawa M, Vagin VV, Reuter M, Hayashi E, Mochizuki AL, Kitamura K, Yamanaka H, Kondoh G, Okawa K, Kuramochi-Miyagawa S, Nakano T, Sachidanandam R, Hannon GJ, Pillai RS, Nakatsuji N, Chuma S.

Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10579-84. doi: 10.1073/pnas.1015447108. Epub 2011 Jun 13.

28.

The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche.

Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, Nagasawa T.

Immunity. 2010 Sep 24;33(3):387-99. doi: 10.1016/j.immuni.2010.08.017.

29.

The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline.

Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S.

Dev Cell. 2009 Dec;17(6):775-87. doi: 10.1016/j.devcel.2009.10.012.

30.

Dynamic clustering and dispersion of lipid rafts contribute to fusion competence of myogenic cells.

Mukai A, Kurisaki T, Sato SB, Kobayashi T, Kondoh G, Hashimoto N.

Exp Cell Res. 2009 Oct 15;315(17):3052-63. doi: 10.1016/j.yexcr.2009.07.010. Epub 2009 Jul 14.

PMID:
19615358
31.

Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development.

Watanabe Y, Inoue K, Okuyama-Yamamoto A, Nakai N, Nakatani J, Nibu K, Sato N, Iiboshi Y, Yusa K, Kondoh G, Takeda J, Terashima T, Takumi T.

J Comp Neurol. 2009 Aug 10;515(5):565-84. doi: 10.1002/cne.22074.

PMID:
19479999
32.

Testicular Angiotensin-converting enzyme with different glycan modification: characterization on glycosylphosphatidylinositol-anchored protein releasing and dipeptidase activities.

Kondoh G, Watanabe H, Tashima Y, Maeda Y, Kinoshita T.

J Biochem. 2009 Jan;145(1):115-21. doi: 10.1093/jb/mvn148. Epub 2008 Nov 4.

PMID:
18984627
33.

Dipeptidase-inactivated tACE action in vivo: selective inhibition of sperm-zona pellucida binding in the mouse.

Deguchi E, Tani T, Watanabe H, Yamada S, Kondoh G.

Biol Reprod. 2007 Nov;77(5):794-802. Epub 2007 Jul 18.

PMID:
17634445
34.

Sleeping beauty transposon-based phenotypic analysis of mice: lack of Arpc3 results in defective trophoblast outgrowth.

Yae K, Keng VW, Koike M, Yusa K, Kouno M, Uno Y, Kondoh G, Gotow T, Uchiyama Y, Horie K, Takeda J.

Mol Cell Biol. 2006 Aug;26(16):6185-96.

35.

In vivo imaging and differential localization of lipid-modified GFP-variant fusions in embryonic stem cells and mice.

Rhee JM, Pirity MK, Lackan CS, Long JZ, Kondoh G, Takeda J, Hadjantonakis AK.

Genesis. 2006 Apr;44(4):202-18.

36.

Retraction: Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice.

Komazawa N, Matsuda M, Kondoh G, Mizunoya W, Iwaki M, Takagi T, Sumikawa Y, Inoue K, Suzuki A, Mak TW, Nakano T, Fushiki T, Takeda J, Shimomura I.

Nat Med. 2005 Jun;11(6):690. No abstract available.

PMID:
15937475
37.

Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization.

Kondoh G, Tojo H, Nakatani Y, Komazawa N, Murata C, Yamagata K, Maeda Y, Kinoshita T, Okabe M, Taguchi R, Takeda J.

Nat Med. 2005 Feb;11(2):160-6. Epub 2005 Jan 23.

PMID:
15665832
38.

p38alpha mitogen-activated protein kinase plays a critical role in cardiomyocyte survival but not in cardiac hypertrophic growth in response to pressure overload.

Nishida K, Yamaguchi O, Hirotani S, Hikoso S, Higuchi Y, Watanabe T, Takeda T, Osuka S, Morita T, Kondoh G, Uno Y, Kashiwase K, Taniike M, Nakai A, Matsumura Y, Miyazaki J, Sudo T, Hongo K, Kusakari Y, Kurihara S, Chien KR, Takeda J, Hori M, Otsu K.

Mol Cell Biol. 2004 Dec;24(24):10611-20.

39.

Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice.

Komazawa N, Matsuda M, Kondoh G, Mizunoya W, Iwaki M, Takagi T, Sumikawa Y, Inoue K, Suzuki A, Mak TW, Nakano T, Fushiki T, Takeda J, Shimomura I.

Nat Med. 2004 Nov;10(11):1208-15. Epub 2004 Oct 17. Retraction in: Komazawa N, Matsuda M, Kondoh G, Mizunoya W, Iwaki M, Takagi T, Sumikawa Y, Inoue K, Suzuki A, Mak TW, Nakano T, Fushiki T, Takeda J, Shimomura I. Nat Med. 2005 Jun;11(6):690.

PMID:
15489860
40.

Ahnak/Desmoyokin is dispensable for proliferation, differentiation, and maintenance of integrity in mouse epidermis.

Kouno M, Kondoh G, Horie K, Komazawa N, Ishii N, Takahashi Y, Takeda J, Hashimoto T.

J Invest Dermatol. 2004 Oct;123(4):700-7.

41.

Tumorigenesis facilitated by Pten deficiency in the skin: evidence of p53-Pten complex formation on the initiation phase.

Komazawa N, Suzuki A, Sano S, Horie K, Matsuura N, Mak TW, Nakano T, Takeda J, Kondoh G.

Cancer Sci. 2004 Aug;95(8):639-43. Retraction in: Tsuruo T. Cancer Sci. 2005 Jun;96(6):377.

42.

Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene.

Yusa K, Horie K, Kondoh G, Kouno M, Maeda Y, Kinoshita T, Takeda J.

Nature. 2004 Jun 24;429(6994):896-9.

43.

Characterization of Sleeping Beauty transposition and its application to genetic screening in mice.

Horie K, Yusa K, Yae K, Odajima J, Fischer SE, Keng VW, Hayakawa T, Mizuno S, Kondoh G, Ijiri T, Matsuda Y, Plasterk RH, Takeda J.

Mol Cell Biol. 2003 Dec;23(24):9189-207.

44.

Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function.

Takagi S, Tojo H, Tomita S, Sano S, Itami S, Hara M, Inoue S, Horie K, Kondoh G, Hosokawa K, Gonzalez FJ, Takeda J.

J Clin Invest. 2003 Nov;112(9):1372-82.

45.

Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins.

Alfieri JA, Martin AD, Takeda J, Kondoh G, Myles DG, Primakoff P.

J Cell Sci. 2003 Jun 1;116(Pt 11):2149-55. Epub 2003 Apr 8.

46.

In vivo cooperation between Bcl-xL and the phosphoinositide 3-kinase-Akt signaling pathway for the protection of epidermal keratinocytes from apoptosis.

Umeda J, Sano S, Kogawa K, Motoyama N, Yoshikawa K, Itami S, Kondoh G, Watanabe T, Takeda J.

FASEB J. 2003 Apr;17(6):610-20.

PMID:
12665473
48.

Targeted disruption of LIG-1 gene results in psoriasiform epidermal hyperplasia.

Suzuki Y, Miura H, Tanemura A, Kobayashi K, Kondoh G, Sano S, Ozawa K, Inui S, Nakata A, Takagi T, Tohyama M, Yoshikawa K, Itami S.

FEBS Lett. 2002 Jun 19;521(1-3):67-71.

49.

Rapid compensation for glycosylphosphatidylinositol anchor deficient keratinocytes after birth: visualization of glycosylphosphatidylinositol-anchored proteins in situ.

Gao XH, Kondoh G, Tarutani M, Hara M, Inoue S, Nakanishi T, Okabe M, Yamaguchi Y, Yoshikawa K, Itami S, Takeda J.

J Invest Dermatol. 2002 Jun;118(6):998-1002.

50.

Efficient biallelic mutagenesis with Cre/loxP-mediated inter-chromosomal recombination.

Koike H, Horie K, Fukuyama H, Kondoh G, Nagata S, Takeda J.

EMBO Rep. 2002 May;3(5):433-7. Epub 2002 Apr 18.

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