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Items: 16

1.

Imidazo[2,1-b]thiazole guanylhydrazones as RSK2 inhibitors.

Andreani A, Granaiola M, Leoni A, Locatelli A, Morigi R, Rambaldi M, Varoli L, Lannigan D, Smith J, Scudiero D, Kondapaka S, Shoemaker RH.

Eur J Med Chem. 2011 Sep;46(9):4311-23. doi: 10.1016/j.ejmech.2011.07.001. Epub 2011 Jul 8.

PMID:
21794960
2.

Cellular inhibition of checkpoint kinase 2 (Chk2) and potentiation of camptothecins and radiation by the novel Chk2 inhibitor PV1019 [7-nitro-1H-indole-2-carboxylic acid {4-[1-(guanidinohydrazone)-ethyl]-phenyl}-amide].

Jobson AG, Lountos GT, Lorenzi PL, Llamas J, Connelly J, Cerna D, Tropea JE, Onda A, Zoppoli G, Kondapaka S, Zhang G, Caplen NJ, Cardellina JH 2nd, Yoo SS, Monks A, Self C, Waugh DS, Shoemaker RH, Pommier Y.

J Pharmacol Exp Ther. 2009 Dec;331(3):816-26. doi: 10.1124/jpet.109.154997. Epub 2009 Sep 9.

3.

Gene expression-signature of belinostat in cell lines is specific for histone deacetylase inhibitor treatment, with a corresponding signature in xenografts.

Monks A, Hose CD, Pezzoli P, Kondapaka S, Vansant G, Petersen KD, Sehested M, Monforte J, Shoemaker RH.

Anticancer Drugs. 2009 Sep;20(8):682-92. doi: 10.1097/CAD.0b013e32832e14e1.

PMID:
19606018
4.

Identification of a Bis-guanylhydrazone [4,4'-Diacetyldiphenylurea-bis(guanylhydrazone); NSC 109555] as a novel chemotype for inhibition of Chk2 kinase.

Jobson AG, Cardellina JH 2nd, Scudiero D, Kondapaka S, Zhang H, Kim H, Shoemaker R, Pommier Y.

Mol Pharmacol. 2007 Oct;72(4):876-84. Epub 2007 Jul 6. Erratum in: Mol Pharmacol. 2008 Oct;74(4):1170.

PMID:
17616632
5.
6.

7-hydroxystaurosporine (UCN-01) inhibition of Akt Thr308 but not Ser473 phosphorylation: a basis for decreased insulin-stimulated glucose transport.

Kondapaka SB, Zarnowski M, Yver DR, Sausville EA, Cushman SW.

Clin Cancer Res. 2004 Nov 1;10(21):7192-8.

7.

Female sex steroid hormones and pregnancy regulate receptors for calcitonin gene-related peptide in rat mesenteric arteries, but not in aorta.

Yallampalli C, Kondapaka SB, Lanlua P, Wimalawansa SJ, Gangula PR.

Biol Reprod. 2004 Apr;70(4):1055-62. Epub 2003 Dec 10.

PMID:
14668209
8.

Perifosine, a novel alkylphospholipid, inhibits protein kinase B activation.

Kondapaka SB, Singh SS, Dasmahapatra GP, Sausville EA, Roy KK.

Mol Cancer Ther. 2003 Nov;2(11):1093-103.

9.

Evidence for the existence of a new receptor for CGRP, which is not CRLR.

Chauhan M, Thota CS, Kondapaka S, Wimalawansa S, Yallampalli C.

Peptides. 2003 Jan;24(1):65-71.

PMID:
12576086
10.

Expression and regulation of calcitonin gene-related Peptide receptor in rat placentas.

Dong YL, Vegiraju S, Gangula PR, Kondapaka SB, Wimalawansa SJ, Yallampalli C.

Biol Reprod. 2002 Oct;67(4):1321-6. Erratum in: Biol Reprod. 2002 Dec;67(6):1996..

PMID:
12297551
11.

Calcitonin gene-related peptide in pregnancy and its emerging receptor heterogeneity.

Yallampalli C, Chauhan M, Thota CS, Kondapaka S, Wimalawansa SJ.

Trends Endocrinol Metab. 2002 Aug;13(6):263-9. Review.

PMID:
12128288
12.

Regulation of calcitonin gene-related peptide receptors in the rat uterus during pregnancy and labor and by progesterone.

Yallampalli C, Gangula PR, Kondapaka S, Fang L, Wimalawansa S.

Biol Reprod. 1999 Oct;61(4):1023-30.

PMID:
10491640
13.

Involvement of calcitonin gene-related peptide in the modulation of human myometrial contractility during pregnancy.

Dong YL, Fang L, Kondapaka S, Gangula PR, Wimalawansa SJ, Yallampalli C.

J Clin Invest. 1999 Sep;104(5):559-65.

14.

Mitogen-activated protein kinase (MAPK) regulates the expression of progelatinase B (MMP-9) in breast epithelial cells.

Reddy KB, Krueger JS, Kondapaka SB, Diglio CA.

Int J Cancer. 1999 Jul 19;82(2):268-73.

15.

Heregulin regulates cytoskeletal reorganization and cell migration through the p21-activated kinase-1 via phosphatidylinositol-3 kinase.

Adam L, Vadlamudi R, Kondapaka SB, Chernoff J, Mendelsohn J, Kumar R.

J Biol Chem. 1998 Oct 23;273(43):28238-46.

16.

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