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Items: 1 to 50 of 150

1.

Effectiveness of pre-entry active tuberculosis and post-entry latent tuberculosis screening in new entrants to the UK: a retrospective, population-based cohort study.

Berrocal-Almanza LC, Harris R, Lalor MK, Muzyamba MC, Were J, O'Connell AM, Mirza A, Kon OM, Lalvani A, Zenner D.

Lancet Infect Dis. 2019 Aug 27. pii: S1473-3099(19)30260-9. doi: 10.1016/S1473-3099(19)30260-9. [Epub ahead of print]

PMID:
31471131
2.

Patterns of systemic and local inflammation in patients with asthma hospitalised with influenza.

Jha A, Dunning J, Tunstall T, Thwaites RS, Hoang LT; MOSAIC Investigators, Kon OM, Zambon MC, Hansel TT, Openshaw PJ.

Eur Respir J. 2019 Aug 7. pii: 1900949. doi: 10.1183/13993003.00949-2019. [Epub ahead of print]

PMID:
31391224
3.

Developing a pathway for the diagnosis and management of ocular tuberculosis. The pan-LOndon Ocular tuberculosis Pathway-LOOP.

Petrushkin H, Sethi C, Potter J, Martin L, Russell G, White V, Ajamil-Rodanes S, Brown M, Breen R, Lipman M, Cropley I, McDermott R, Roche A, Booth H, Milburn J, Darmalingam M, Lee R, Pavesio C, Stanford M, Kon OM, Bothamley G.

Eye (Lond). 2019 Aug 6. doi: 10.1038/s41433-019-0543-7. [Epub ahead of print] Review. No abstract available.

PMID:
31388132
4.

Fluoroquinolones and isoniazid resistant TB: implications for the 2018 WHO guidance.

Stagg HR, Bothamley GH, Davidson JA, Kunst H, Lalor MK, Lipman MC, Loutet MG, Lozewicz S, Mohiyuddin T, Abbara A, Alexander E, Booth H, Creer DD, Harris RJ, Kon OM, Loebinger MR, McHugh TD, Milburn HJ, Palchaudhuri P, Phillips PPJ, Schmok E, Taylor L, Abubakar I; London INH-R TB study group.

Eur Respir J. 2019 Aug 22. pii: 1900982. doi: 10.1183/13993003.00982-2019. [Epub ahead of print]

PMID:
31371444
5.

Interferon gamma release assays for Diagnostic Evaluation of Active tuberculosis (IDEA): test accuracy study and economic evaluation.

Takwoingi Y, Whitworth H, Rees-Roberts M, Badhan A, Partlett C, Green N, Boakye A, Lambie H, Marongiu L, Jit M, White P, Deeks JJ, Kon OM, Lalvani A.

Health Technol Assess. 2019 May;23(23):1-152. doi: 10.3310/hta23230.

6.

Engaging with civil society to improve access to LTBI screening for new migrants in England: a qualitative study.

Berrocal-Almanza LC, Botticello J, Piotrowski H, Karnani N, Kon OM, Lalvani A, Zenner D.

Int J Tuberc Lung Dis. 2019 May 1;23(5):563-570. doi: 10.5588/ijtld.18.0230.

PMID:
31097064
7.

An update on multidrug-resistant tuberculosis .

Park M, Satta G, Kon OM.

Clin Med (Lond). 2019 Mar;19(2):135-139. doi: 10.7861/clinmedicine.19-2-135.

8.

Clinical utility of existing and second-generation interferon-γ release assays for diagnostic evaluation of tuberculosis: an observational cohort study.

Whitworth HS, Badhan A, Boakye AA, Takwoingi Y, Rees-Roberts M, Partlett C, Lambie H, Innes J, Cooke G, Lipman M, Conlon C, Macallan D, Chua F, Post FA, Wiselka M, Woltmann G, Deeks JJ, Kon OM, Lalvani A; Interferon-γ Release Assays for Diagnostic Evaluation of Active Tuberculosis study group.

Lancet Infect Dis. 2019 Feb;19(2):193-202. doi: 10.1016/S1473-3099(18)30613-3. Epub 2019 Jan 14. Erratum in: Lancet Infect Dis. 2019 Feb;19(2):e39. Lancet Infect Dis. 2019 Mar;19(3):e64.

9.

Pleural tuberculosis: a key differential diagnosis for pleural thickening, even without obvious risk factors for tuberculosis in a low incidence setting.

Philip KEJ, Kon OM, Roddie M, Ross C.

BMJ Case Rep. 2018 Oct 27;2018. pii: bcr-2018-224992. doi: 10.1136/bcr-2018-224992.

PMID:
30368474
10.

Two interferon gamma release assays for predicting active tuberculosis: the UK PREDICT TB prognostic test study.

Abubakar I, Lalvani A, Southern J, Sitch A, Jackson C, Onyimadu O, Lipman M, Deeks JJ, Griffiths C, Bothamley G, Kon OM, Hayward A, Lord J, Drobniewski F.

Health Technol Assess. 2018 Oct;22(56):1-96. doi: 10.3310/hta22560.

11.

Prognostic value of interferon-γ release assays and tuberculin skin test in predicting the development of active tuberculosis (UK PREDICT TB): a prospective cohort study.

Abubakar I, Drobniewski F, Southern J, Sitch AJ, Jackson C, Lipman M, Deeks JJ, Griffiths C, Bothamley G, Lynn W, Burgess H, Mann B, Imran A, Sridhar S, Tsou CY, Nikolayevskyy V, Rees-Roberts M, Whitworth H, Kon OM, Haldar P, Kunst H, Anderson S, Hayward A, Watson JM, Milburn H, Lalvani A; PREDICT Study Team.

Lancet Infect Dis. 2018 Oct;18(10):1077-1087. doi: 10.1016/S1473-3099(18)30355-4. Epub 2018 Aug 30.

12.

The Collaborative Ocular Tuberculosis Study (COTS)-1: A Multinational Description of the Spectrum of Choroidal Involvement in 245 Patients with Tubercular Uveitis.

Agrawal R, Gunasekeran DV, Agarwal A, Carreño E, Aggarwal K, Gupta B, Raje D, Murthy SI, Westcott M, Chee SP, McCluskey P, Ling HS, Teoh S, Cimino L, Biswas J, Narain S, Agarwal M, Mahendradas P, Khairallah M, Jones N, Tugal-Tutkun I, Babu K, Basu S, Lee R, Al-Dhibi H, Bodaghi B, Invernizzi A, Goldstein DA, Herbort CP, Barisani-Asenbauer T, González-López JJ, Androudi S, Bansal R, Moharana B, Mahajan S, Esposti S, Tasiopoulou A, Nadarajah S, Agarwal M, Abraham S, Vala R, Lord J, Singh R, Sharma A, Sharma K, Zierhut M, Kon OM, Kempen J, Cunningham ET, Rousselot A, Nguyen QD, Pavesio C, Gupta V.

Ocul Immunol Inflamm. 2018 Aug 29:1-11. doi: 10.1080/09273948.2018.1489061. [Epub ahead of print]

PMID:
30156979
13.

Global Variations and Challenges With Tubercular Uveitis in the Collaborative Ocular Tuberculosis Study.

Agrawal R, Gunasekeran DV, Raje D, Agarwal A, Nguyen QD, Kon OM, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study Group.

Invest Ophthalmol Vis Sci. 2018 Aug 1;59(10):4162-4171. doi: 10.1167/iovs.18-24102.

14.

Mycobacterium chimaera infection following cardiac surgery in the United Kingdom: clinical features and outcome of the first 30 cases.

Scriven JE, Scobie A, Verlander NQ, Houston A, Collyns T, Cajic V, Kon OM, Mitchell T, Rahama O, Robinson A, Withama S, Wilson P, Maxwell D, Agranoff D, Davies E, Llewelyn M, Soo SS, Sahota A, Cooper MA, Hunter M, Tomlins J, Tiberi S, Kendall S, Dedicoat M, Alexander E, Fenech T, Zambon M, Lamagni T, Smith EG, Chand M.

Clin Microbiol Infect. 2018 Nov;24(11):1164-1170. doi: 10.1016/j.cmi.2018.04.027. Epub 2018 May 25.

15.

Diabetes mellitus and latent tuberculosis infection: baseline analysis of a large UK cohort.

Jackson C, Southern J, Lalvani A, Drobniewski F, Griffiths CJ, Lipman M, Bothamley GH, Deeks JJ, Imran A, Kon OM, Mpofu S, Nikolayevskyy V, Rees-Roberts M, Sitch A, Sridhar S, Tsou CY, Whitworth H, Abubakar I.

Thorax. 2019 Jan;74(1):91-94. doi: 10.1136/thoraxjnl-2017-211124. Epub 2018 May 15.

16.

Bronchial mucosal IFN-α/β and pattern recognition receptor expression in patients with experimental rhinovirus-induced asthma exacerbations.

Zhu J, Message SD, Mallia P, Kebadze T, Contoli M, Ward CK, Barnathan ES, Mascelli MA, Kon OM, Papi A, Stanciu LA, Edwards MR, Jeffery PK, Johnston SL.

J Allergy Clin Immunol. 2019 Jan;143(1):114-125.e4. doi: 10.1016/j.jaci.2018.04.003. Epub 2018 Apr 24.

17.

THE COLLABORATIVE OCULAR TUBERCULOSIS STUDY (COTS)-1: A Multinational Review of 251 Patients With Tubercular Retinal Vasculitis.

Gunasekeran DV, Agrawal R, Agarwal A, Carreño E, Raje D, Aggarwal K, Kon OM, Nguyen QD, Pavesio C, Gupta V; COTS-1 Study Group.

Retina. 2019 Aug;39(8):1623-1630. doi: 10.1097/IAE.0000000000002194.

PMID:
29697588
18.

Absorption of Nasal and Bronchial Fluids: Precision Sampling of the Human Respiratory Mucosa and Laboratory Processing of Samples.

Thwaites RS, Jarvis HC, Singh N, Jha A, Pritchard A, Fan H, Tunstall T, Nanan J, Nadel S, Kon OM, Openshaw PJ, Hansel TT.

J Vis Exp. 2018 Jan 21;(131). doi: 10.3791/56413.

19.

Role of airway glucose in bacterial infections in patients with chronic obstructive pulmonary disease.

Mallia P, Webber J, Gill SK, Trujillo-Torralbo MB, Calderazzo MA, Finney L, Bakhsoliani E, Farne H, Singanayagam A, Footitt J, Hewitt R, Kebadze T, Aniscenko J, Padmanaban V, Molyneaux PL, Adcock IM, Barnes PJ, Ito K, Elkin SL, Kon OM, Cookson WO, Moffat MF, Johnston SL, Tregoning JS.

J Allergy Clin Immunol. 2018 Sep;142(3):815-823.e6. doi: 10.1016/j.jaci.2017.10.017. Epub 2018 Jan 5.

20.

The Collaborative Ocular Tuberculosis Study (COTS)-1 Report 3: Polymerase Chain Reaction in the Diagnosis and Management of Tubercular Uveitis: Global Trends.

Agarwal A, Agrawal R, Gunasekaran DV, Raje D, Gupta B, Aggarwal K, Murthy SL, Westcott M, Chee SP, McCluskey P, Ling HS, Teoh S, Cimino L, Biswas J, Narain S, Agarwal M, Mahendradas P, Khairallah M, Jones N, Tugal-Tutkun I, Babu K, Basu S, Carreño E, Lee R, Al-Dhibi H, Bodaghi B, Invernizzi A, Goldstein DA, Herbort CP, Barisani-Asenbauer T, González-López JJ, Androudi S, Bansal R, Moharana B, Mahajan S, Esposti S, Tasiopoulou A, Nadarajah S, Agarwal M, Abraham S, Vala R, Singh R, Sharma A, Sharma K, Zierhut M, Kon OM, Cunningham E, Nguyen QD, Pavesio C, Gupta V.

Ocul Immunol Inflamm. 2019;27(3):465-473. doi: 10.1080/09273948.2017.1406529. Epub 2017 Dec 20.

21.

Mycobacterium tuberculosis and whole-genome sequencing: how close are we to unleashing its full potential?

Satta G, Lipman M, Smith GP, Arnold C, Kon OM, McHugh TD.

Clin Microbiol Infect. 2018 Jun;24(6):604-609. doi: 10.1016/j.cmi.2017.10.030. Epub 2017 Nov 3. Review.

22.

Clinical Features and Outcomes of Patients With Tubercular Uveitis Treated With Antitubercular Therapy in the Collaborative Ocular Tuberculosis Study (COTS)-1.

Agrawal R, Gunasekeran DV, Grant R, Agarwal A, Kon OM, Nguyen QD, Pavesio C, Gupta V; Collaborative Ocular Tuberculosis Study (COTS)–1 Study Group.

JAMA Ophthalmol. 2017 Dec 1;135(12):1318-1327. doi: 10.1001/jamaophthalmol.2017.4485.

23.

Innate activation of human primary epithelial cells broadens the host response to Mycobacterium tuberculosis in the airways.

Reuschl AK, Edwards MR, Parker R, Connell DW, Hoang L, Halliday A, Jarvis H, Siddiqui N, Wright C, Bremang S, Newton SM, Beverley P, Shattock RJ, Kon OM, Lalvani A.

PLoS Pathog. 2017 Sep 1;13(9):e1006577. doi: 10.1371/journal.ppat.1006577. eCollection 2017 Sep.

24.

Rhinovirus induction of fractalkine (CX3CL1) in airway and peripheral blood mononuclear cells in asthma.

Upton N, Jackson DJ, Nikonova AA, Hingley-Wilson S, Khaitov M, Del Rosario A, Traub S, Trujillo-Torralbo MB, Habibi M, Elkin SL, Kon OM, Edwards MR, Mallia P, Footitt J, Macintyre J, Stanciu LA, Johnston SL, Sykes A.

PLoS One. 2017 Aug 31;12(8):e0183864. doi: 10.1371/journal.pone.0183864. eCollection 2017.

25.

Post-tuberculous fibrosing mediastinitis: a review of the literature.

Wu Z, Jarvis H, Howard LS, Wright C, Kon OM.

BMJ Open Respir Res. 2017 May 8;4(1):e000174. doi: 10.1136/bmjresp-2016-000174. eCollection 2017. Review.

26.

Adverse Effects and Choice between the Injectable Agents Amikacin and Capreomycin in Multidrug-Resistant Tuberculosis.

Arnold A, Cooke GS, Kon OM, Dedicoat M, Lipman M, Loyse A, Chis Ster I, Harrison TS.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02586-16. doi: 10.1128/AAC.02586-16. Print 2017 Sep.

27.

A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13).

Hansel TT, Tunstall T, Trujillo-Torralbo MB, Shamji B, Del-Rosario A, Dhariwal J, Kirk PDW, Stumpf MPH, Koopmann J, Telcian A, Aniscenko J, Gogsadze L, Bakhsoliani E, Stanciu L, Bartlett N, Edwards M, Walton R, Mallia P, Hunt TM, Hunt TL, Hunt DG, Westwick J, Edwards M, Kon OM, Jackson DJ, Johnston SL.

EBioMedicine. 2017 May;19:128-138. doi: 10.1016/j.ebiom.2017.03.033. Epub 2017 Mar 28.

28.

Drug-induced liver injury from antituberculous treatment: a retrospective study from a large TB centre in the UK.

Abbara A, Chitty S, Roe JK, Ghani R, Collin SM, Ritchie A, Kon OM, Dzvova J, Davidson H, Edwards TE, Hateley C, Routledge M, Buckley J, Davidson RN, John L.

BMC Infect Dis. 2017 Mar 24;17(1):231. doi: 10.1186/s12879-017-2330-z.

29.

Stratification of Latent Mycobacterium tuberculosis Infection by Cellular Immune Profiling.

Halliday A, Whitworth H, Kottoor SH, Niazi U, Menzies S, Kunst H, Bremang S, Badhan A, Beverley P, Kon OM, Lalvani A.

J Infect Dis. 2017 May 1;215(9):1480-1487. doi: 10.1093/infdis/jix107.

30.

Evaluation of prediagnosis emergency department presentations in patients with active tuberculosis: the role of chest radiography, risk factors and symptoms.

Appleton SC, Connell DW, Singanayagam A, Bradley P, Pan D, Sanderson F, Cleaver B, Rahman A, Kon OM.

BMJ Open Respir Res. 2017 Jan 17;4(1):e000154. doi: 10.1136/bmjresp-2016-000154. eCollection 2017.

31.

Proteomic Analysis of Kveim Reagent Identifies Targets of Cellular Immunity in Sarcoidosis.

Eberhardt C, Thillai M, Parker R, Siddiqui N, Potiphar L, Goldin R, Timms JF, Wells AU, Kon OM, Wickremasinghe M, Mitchell D, Weeks ME, Lalvani A.

PLoS One. 2017 Jan 23;12(1):e0170285. doi: 10.1371/journal.pone.0170285. eCollection 2017.

32.

Drug resistant TB: UK multicentre study (DRUMS): Treatment, management and outcomes in London and West Midlands 2008-2014.

Arnold A, Cooke GS, Kon OM, Dedicoat M, Lipman M, Loyse A, Butcher PD, Ster IC, Harrison TS.

J Infect. 2017 Mar;74(3):260-271. doi: 10.1016/j.jinf.2016.12.005. Epub 2016 Dec 18.

33.

Evaluation of serum inflammatory biomarkers as predictors of treatment outcome in pulmonary tuberculosis.

Singanayagam A, Manalan K, Connell DW, Chalmers JD, Sridhar S, Ritchie AI, Lalvani A, Wickremasinghe M, Kon OM.

Int J Tuberc Lung Dis. 2016 Dec;20(12):1653-1660.

34.

Factors which influence treatment initiation for pulmonary non-tuberculous mycobacterium infection in HIV negative patients; a multicentre observational study.

Rawson TM, Abbara A, Kranzer K, Ritchie A, Milburn J, Brown T, Adeboyeku D, Buckley J, Davidson RN, Berry M, Kon OM, John L.

Respir Med. 2016 Nov;120:101-108. doi: 10.1016/j.rmed.2016.10.001. Epub 2016 Oct 6.

35.

Tuberculosis or sarcoidosis: Opposite ends of the same disease spectrum?

Agrawal R, Kee AR, Ang L, Tun Hang Y, Gupta V, Kon OM, Mitchell D, Zierhut M, Pavesio C.

Tuberculosis (Edinb). 2016 May;98:21-6. doi: 10.1016/j.tube.2016.01.003. Epub 2016 Jan 18. Review.

PMID:
27156614
36.

Anti-tubercular therapy for intraocular tuberculosis: A systematic review and meta-analysis.

Kee AR, Gonzalez-Lopez JJ, Al-Hity A, Gupta B, Lee CS, Gunasekeran DV, Jayabalan N, Grant R, Kon OM, Gupta V, Westcott M, Pavesio C, Agrawal R.

Surv Ophthalmol. 2016 Sep-Oct;61(5):628-53. doi: 10.1016/j.survophthal.2016.03.001. Epub 2016 Mar 10. Review.

37.

Trapped without a diagnosis: Tumour necrosis factor receptor-associated periodic syndrome (TRAPS).

Kirresh A, Everitt A, Kon OM, DasGupta R, Pickering MC, Lachmann HJ.

Pract Neurol. 2016 Aug;16(4):304-7. doi: 10.1136/practneurol-2015-001342. Epub 2016 Mar 10.

PMID:
26965498
38.

Erratum: RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.

Jozwik A, Habibi MS, Paras A, Zhu J, Guvenel A, Dhariwal J, Almond M, Wong EH, Sykes A, Maybeno M, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C.

Nat Commun. 2016 Mar 9;7:11011. doi: 10.1038/ncomms11011. No abstract available.

39.

Why should we continue to do acute general takes?

Kon OM, Oldfield WG.

Future Hosp J. 2016 Feb;3(1):68-69. doi: 10.7861/futurehosp.3-1-68.

40.

PD-1 Expression and Cytokine Secretion Profiles of Mycobacterium tuberculosis-Specific CD4+ T-Cell Subsets; Potential Correlates of Containment in HIV-TB Co-Infection.

Pollock KM, Montamat-Sicotte DJ, Grass L, Cooke GS, Kapembwa MS, Kon OM, Sampson RD, Taylor GP, Lalvani A.

PLoS One. 2016 Jan 12;11(1):e0146905. doi: 10.1371/journal.pone.0146905. eCollection 2016.

41.

RSV-specific airway resident memory CD8+ T cells and differential disease severity after experimental human infection.

Jozwik A, Habibi MS, Paras A, Zhu J, Guvenel A, Dhariwal J, Almond M, Wong EHC, Sykes A, Maybeno M, Del Rosario J, Trujillo-Torralbo MB, Mallia P, Sidney J, Peters B, Kon OM, Sette A, Johnston SL, Openshaw PJ, Chiu C.

Nat Commun. 2015 Dec 21;6:10224. doi: 10.1038/ncomms10224. Erratum in: Nat Commun. 2016;7:11011.

42.

Differences in antigen-specific CD4+ responses to opportunistic infections in HIV infection.

Pollock KM, Montamat-Sicotte DJ, Cooke GS, Kapembwa MS, Kon OM, Grass L, Sampson RD, Taylor GP, Lalvani A.

Immun Inflamm Dis. 2015 Sep;3(3):141-53. doi: 10.1002/iid3.50. Epub 2015 Apr 29.

43.

Vitamin D deficiency and TB disease phenotype.

Pareek M, Innes J, Sridhar S, Grass L, Connell D, Woltmann G, Wiselka M, Martineau AR, Kon OM, Dedicoat M, Lalvani A.

Thorax. 2015 Dec;70(12):1171-80. doi: 10.1136/thoraxjnl-2014-206617. Epub 2015 Sep 23.

44.

Nasal Lipopolysaccharide Challenge and Cytokine Measurement Reflects Innate Mucosal Immune Responsiveness.

Dhariwal J, Kitson J, Jones RE, Nicholson G, Tunstall T, Walton RP, Francombe G, Gilbert J, Tan AJ, Murdoch R, Kon OM, Openshaw PJ, Hansel TT.

PLoS One. 2015 Sep 14;10(9):e0135363. doi: 10.1371/journal.pone.0135363. eCollection 2015.

45.

Viral hepatitis prevalence in patients with active and latent tuberculosis.

Nooredinvand HA, Connell DW, Asgheddi M, Abdullah M, O'Donoghue M, Campbell L, Wickremasinghe MI, Lalvani A, Kon OM, Khan SA.

World J Gastroenterol. 2015 Aug 7;21(29):8920-6. doi: 10.3748/wjg.v21.i29.8920.

46.

Author's reply to Clifford and colleagues.

Kon OM.

BMJ. 2015 Apr 28;350:h2229. doi: 10.1136/bmj.h2229. No abstract available.

PMID:
25922202
47.

Risk factors for the misdiagnosis of tuberculosis in the UK, 2001-2011.

Pedrazzoli D, Abubakar I, Potts H, Hunter PR, Kruijshaar ME, Kon OM, Southern J.

Eur Respir J. 2015 Aug;46(2):564-7. doi: 10.1183/09031936.00227914. Epub 2015 Apr 16. No abstract available.

48.

Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD.

Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo MB, Telcian AG, Del Rosario A, Chang C, Peh HY, Kebadze T, Aniscenko J, Stanciu L, Essilfie-Quaye S, Ito K, Barnes PJ, Elkin SL, Kon OM, Wong WS, Adcock IM, Johnston SL.

Chest. 2016 Jan;149(1):62-73. doi: 10.1378/chest.14-2637. Epub 2016 Jan 6.

49.

Screening tests for tuberculosis before starting biological therapy.

Hewitt RJ, Francis M, Singanayagam A, Kon OM.

BMJ. 2015 Mar 5;350:h1060. doi: 10.1136/bmj.h1060. No abstract available.

PMID:
25742884
50.

The national TB strategy: jointly taking responsibility for TB control?

Kon OM, Ormerod LP.

Thorax. 2015 Mar;70(3):211-2. doi: 10.1136/thoraxjnl-2015-206808. Epub 2015 Feb 3. No abstract available.

PMID:
25650102

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