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Items: 19

1.

The Beginning of Base Editing: An Interview with Alexis C. Komor and Nicole M. Gaudelli.

Davies K, Komor AC, Gaudelli NM.

CRISPR J. 2019 Apr;2:81-90. doi: 10.1089/crispr.2019.29050.kda. No abstract available.

PMID:
30998094
2.

Genome, Epigenome, and Transcriptome Editing via Chemical Modification of Nucleobases in Living Cells.

Ranzau BL, Komor AC.

Biochemistry. 2019 Feb 5;58(5):330-335. doi: 10.1021/acs.biochem.8b00958. Epub 2018 Dec 12.

PMID:
30500171
3.

Publisher Correction: Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR.

Nature. 2018 Jul;559(7714):E8. doi: 10.1038/s41586-018-0070-x.

PMID:
29720650
4.

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage.

Gaudelli NM, Komor AC, Rees HA, Packer MS, Badran AH, Bryson DI, Liu DR.

Nature. 2017 Nov 23;551(7681):464-471. doi: 10.1038/nature24644. Epub 2017 Oct 25. Erratum in: Nature. 2018 May 2;:.

5.

Editing the Genome Without Double-Stranded DNA Breaks.

Komor AC, Badran AH, Liu DR.

ACS Chem Biol. 2018 Feb 16;13(2):383-388. doi: 10.1021/acschembio.7b00710. Epub 2017 Oct 9. Review.

6.

Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity.

Komor AC, Zhao KT, Packer MS, Gaudelli NM, Waterbury AL, Koblan LW, Kim YB, Badran AH, Liu DR.

Sci Adv. 2017 Aug 30;3(8):eaao4774. doi: 10.1126/sciadv.aao4774. eCollection 2017 Aug.

7.

Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery.

Rees HA, Komor AC, Yeh WH, Caetano-Lopes J, Warman M, Edge ASB, Liu DR.

Nat Commun. 2017 Jun 6;8:15790. doi: 10.1038/ncomms15790.

8.

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

Komor AC, Badran AH, Liu DR.

Cell. 2017 Apr 20;169(3):559. doi: 10.1016/j.cell.2017.04.005. No abstract available.

9.

Increasing the genome-targeting scope and precision of base editing with engineered Cas9-cytidine deaminase fusions.

Kim YB, Komor AC, Levy JM, Packer MS, Zhao KT, Liu DR.

Nat Biotechnol. 2017 Apr;35(4):371-376. doi: 10.1038/nbt.3803. Epub 2017 Feb 13.

10.

CRISPR-Based Technologies for the Manipulation of Eukaryotic Genomes.

Komor AC, Badran AH, Liu DR.

Cell. 2017 Jan 12;168(1-2):20-36. doi: 10.1016/j.cell.2016.10.044. Epub 2016 Nov 17. Review. Erratum in: Cell. 2017 Apr 20;169(3):559.

11.

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage.

Komor AC, Kim YB, Packer MS, Zuris JA, Liu DR.

Nature. 2016 May 19;533(7603):420-4. doi: 10.1038/nature17946. Epub 2016 Apr 20.

12.

Targeted Chemotherapy with Metal Complexes.

Weidmann AG, Komor AC, Barton JK.

Comments Mod Chem A Comments Inorg Chem. 2014 May;34(3-4):114-123.

13.

An unusual ligand coordination gives rise to a new family of rhodium metalloinsertors with improved selectivity and potency.

Komor AC, Barton JK.

J Am Chem Soc. 2014 Oct 8;136(40):14160-72. doi: 10.1021/ja5072064. Epub 2014 Sep 25.

14.

An inducible, isogenic cancer cell line system for targeting the state of mismatch repair deficiency.

Bailis JM, Gordon ML, Gurgel JL, Komor AC, Barton JK, Kirsch IR.

PLoS One. 2013 Oct 29;8(10):e78726. doi: 10.1371/journal.pone.0078726. eCollection 2013.

15.

Biological effects of simple changes in functionality on rhodium metalloinsertors.

Weidmann AG, Komor AC, Barton JK.

Philos Trans A Math Phys Eng Sci. 2013 Jun 17;371(1995):20120117. doi: 10.1098/rsta.2012.0117. Print 2013 Jul 28.

16.

The path for metal complexes to a DNA target.

Komor AC, Barton JK.

Chem Commun (Camb). 2013 May 7;49(35):3617-30. doi: 10.1039/c3cc00177f. Review.

17.

Cell-selective biological activity of rhodium metalloinsertors correlates with subcellular localization.

Komor AC, Schneider CJ, Weidmann AG, Barton JK.

J Am Chem Soc. 2012 Nov 21;134(46):19223-33. doi: 10.1021/ja3090687. Epub 2012 Nov 8. Erratum in: J Am Chem Soc. 2013 Feb 20;135(7):2863.

18.

Selective cytotoxicity of rhodium metalloinsertors in mismatch repair-deficient cells.

Ernst RJ, Komor AC, Barton JK.

Biochemistry. 2011 Dec 20;50(50):10919-28. doi: 10.1021/bi2015822. Epub 2011 Nov 21.

19.

A hydrogen-bond facilitated cycle for oxygen reduction by an acid- and base-compatible iron platform.

Soo HS, Komor AC, Iavarone AT, Chang CJ.

Inorg Chem. 2009 Nov 2;48(21):10024-35. doi: 10.1021/ic9006668.

PMID:
19780564

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