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Items: 18

1.

JUN dependency in distinct early and late BRAF inhibition adaptation states of melanoma.

Titz B, Lomova A, Le A, Hugo W, Kong X, Ten Hoeve J, Friedman M, Shi H, Moriceau G, Song C, Hong A, Atefi M, Li R, Komisopoulou E, Ribas A, Lo RS, Graeber TG.

Cell Discov. 2016 Sep 6;2:16028. doi: 10.1038/celldisc.2016.28. eCollection 2016.

2.

Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors.

Anderson JL, Titz B, Akiyama R, Komisopoulou E, Park A, Tap WD, Graeber TG, Denny CT.

Mol Cancer Res. 2014 Dec;12(12):1740-54. doi: 10.1158/1541-7786.MCR-14-0159. Epub 2014 Aug 4.

3.

Adenovirus E4ORF1-induced MYC activation promotes host cell anabolic glucose metabolism and virus replication.

Thai M, Graham NA, Braas D, Nehil M, Komisopoulou E, Kurdistani SK, McCormick F, Graeber TG, Christofk HR.

Cell Metab. 2014 Apr 1;19(4):694-701. doi: 10.1016/j.cmet.2014.03.009.

4.

Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin.

Zimman A, Titz B, Komisopoulou E, Biswas S, Graeber TG, Podrez EA.

PLoS One. 2014 Jan 6;9(1):e84488. doi: 10.1371/journal.pone.0084488. eCollection 2014.

5.

Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity.

Kidani Y, Elsaesser H, Hock MB, Vergnes L, Williams KJ, Argus JP, Marbois BN, Komisopoulou E, Wilson EB, Osborne TF, Graeber TG, Reue K, Brooks DG, Bensinger SJ.

Nat Immunol. 2013 May;14(5):489-99. doi: 10.1038/ni.2570. Epub 2013 Apr 7.

6.

An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells.

Rohle D, Popovici-Muller J, Palaskas N, Turcan S, Grommes C, Campos C, Tsoi J, Clark O, Oldrini B, Komisopoulou E, Kunii K, Pedraza A, Schalm S, Silverman L, Miller A, Wang F, Yang H, Chen Y, Kernytsky A, Rosenblum MK, Liu W, Biller SA, Su SM, Brennan CW, Chan TA, Graeber TG, Yen KE, Mellinghoff IK.

Science. 2013 May 3;340(6132):626-30. doi: 10.1126/science.1236062. Epub 2013 Apr 4.

7.

Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses.

Teles RM, Graeber TG, Krutzik SR, Montoya D, Schenk M, Lee DJ, Komisopoulou E, Kelly-Scumpia K, Chun R, Iyer SS, Sarno EN, Rea TH, Hewison M, Adams JS, Popper SJ, Relman DA, Stenger S, Bloom BR, Cheng G, Modlin RL.

Science. 2013 Mar 22;339(6126):1448-53. doi: 10.1126/science.1233665. Epub 2013 Feb 28.

8.

An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity.

Williams KJ, Argus JP, Zhu Y, Wilks MQ, Marbois BN, York AG, Kidani Y, Pourzia AL, Akhavan D, Lisiero DN, Komisopoulou E, Henkin AH, Soto H, Chamberlain BT, Vergnes L, Jung ME, Torres JZ, Liau LM, Christofk HR, Prins RM, Mischel PS, Reue K, Graeber TG, Bensinger SJ.

Cancer Res. 2013 May 1;73(9):2850-62. doi: 10.1158/0008-5472.CAN-13-0382-T. Epub 2013 Feb 25.

9.

Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death.

Graham NA, Tahmasian M, Kohli B, Komisopoulou E, Zhu M, Vivanco I, Teitell MA, Wu H, Ribas A, Lo RS, Mellinghoff IK, Mischel PS, Graeber TG.

Mol Syst Biol. 2012 Jun 26;8:589. doi: 10.1038/msb.2012.20.

10.

NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy.

Schenk M, Krutzik SR, Sieling PA, Lee DJ, Teles RM, Ochoa MT, Komisopoulou E, Sarno EN, Rea TH, Graeber TG, Kim S, Cheng G, Modlin RL.

Nat Med. 2012 Mar 25;18(4):555-63. doi: 10.1038/nm.2650.

11.

Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression.

Drake JM, Graham NA, Stoyanova T, Sedghi A, Goldstein AS, Cai H, Smith DA, Zhang H, Komisopoulou E, Huang J, Graeber TG, Witte ON.

Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1643-8. doi: 10.1073/pnas.1120985109. Epub 2012 Jan 17.

12.

MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy.

Liu PT, Wheelwright M, Teles R, Komisopoulou E, Edfeldt K, Ferguson B, Mehta MD, Vazirnia A, Rea TH, Sarno EN, Graeber TG, Modlin RL.

Nat Med. 2012 Jan 29;18(2):267-73. doi: 10.1038/nm.2584.

13.

18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers.

Palaskas N, Larson SM, Schultz N, Komisopoulou E, Wong J, Rohle D, Campos C, Yannuzzi N, Osborne JR, Linkov I, Kastenhuber ER, Taschereau R, Plaisier SB, Tran C, Heguy A, Wu H, Sander C, Phelps ME, Brennan C, Port E, Huse JT, Graeber TG, Mellinghoff IK.

Cancer Res. 2011 Aug 1;71(15):5164-74. doi: 10.1158/0008-5472.CAN-10-4633. Epub 2011 Jun 6.

14.

Global phosphoproteomics reveals crosstalk between Bcr-Abl and negative feedback mechanisms controlling Src signaling.

Rubbi L, Titz B, Brown L, Galvan E, Komisopoulou E, Chen SS, Low T, Tahmasian M, Skaggs B, Müschen M, Pellegrini M, Graeber TG.

Sci Signal. 2011 Mar 29;4(166):ra18. doi: 10.1126/scisignal.2001314.

15.

The proximal signaling network of the BCR-ABL1 oncogene shows a modular organization.

Titz B, Low T, Komisopoulou E, Chen SS, Rubbi L, Graeber TG.

Oncogene. 2010 Nov 4;29(44):5895-910. doi: 10.1038/onc.2010.331. Epub 2010 Aug 9.

16.

Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis.

Zimman A, Chen SS, Komisopoulou E, Titz B, Martínez-Pinna R, Kafi A, Berliner JA, Graeber TG.

J Proteome Res. 2010 Jun 4;9(6):2812-24. doi: 10.1021/pr901194x.

17.

Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants.

Skaggs BJ, Gorre ME, Ryvkin A, Burgess MR, Xie Y, Han Y, Komisopoulou E, Brown LM, Loo JA, Landaw EM, Sawyers CL, Graeber TG.

Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19466-71. Epub 2006 Dec 12.

18.

A method of image registration for small animal, multi-modality imaging.

Chow PL, Stout DB, Komisopoulou E, Chatziioannou AF.

Phys Med Biol. 2006 Jan 21;51(2):379-90. Epub 2006 Jan 4.

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